Objective To prospectively evaluate functional magnetic resonance(MR) imaging and magnetoencephalography(MEG ),as compared with direct electrical cortical stimulation(DECS ),for identification of the primary motor ***...
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Objective To prospectively evaluate functional magnetic resonance(MR) imaging and magnetoencephalography(MEG ),as compared with direct electrical cortical stimulation(DECS ),for identification of the primary motor *** 8 patinents with tumors of different aetiology in or around motor cortex were *** was performed using a T2 weighted gradient echo BOLD sequence at 1.5T MR scanner,MEG study was performed using a whole - head Omega 151 - channel gradiometer *** the functional studies,the patients were asked to perform a unilateral finger tapping motor *** and MEG localizations were compared with the results of intraoperative electrical cortical *** The MEG localization results agreed with the intraoperative electrical cortical stimulation results in 8 *** fMRI localization results agreed with the intraoperative electrical cortical stimulation results in 3 *** all 5 patients with a false localization,3 patients showed neighbouring results of fMRI and MEG,2 patients showed discordance between fMRI and *** Although fMRI could show the activations of primary motor cortex,supplementary motor cortex,premotor area and other motor - related areas,MEG seemed to be superior for locating the primary motor cortex.
The effects of electromagnetic fields(EMFs) emitted by mobile phones on humans central nervous system(CNS) have been the subject of a large number of experimental studies in recent years. However,those results showed ...
The effects of electromagnetic fields(EMFs) emitted by mobile phones on humans central nervous system(CNS) have been the subject of a large number of experimental studies in recent years. However,those results showed were *** present study investigated the effects of 900MHz EMF on behavioral and histopathology changes of brain of adult Spraque - Dawley(SD) *** group was housed in our animal room during the exposure *** group was placed in the exposure box but not exposed to EMF(power density:0mw/cm,2 h/day for consecutive 28 days).EMF group rats were exposed to 900 MHz EMF(power density:1 mw/cm,2 h/day for consecutive 28 days) in an exposure *** of those rats were subjected to behavioral tests by Morris water maze or histologically change in SVZ(subventricular zone ) and SGZ(subgranular zone) of *** the BrdU cells in SVZand SGZ were *** showed that the latency of place navigation was significantly increased(P<0.05) at timepoints of Oh,24h, 48h and 72h after exposure,the times through platform and the time in target area were obviously decreased (P<0.05 ) in spatial probe test in EMF group rats compared with those in sham group *** structural changes of hippocampus after exposure including celluer edema,vessel stenosis and neurons loss. Apoptotic cells in hippocampus was significant increased in the exposure group(P<0.05 ).The number of BrdU cells were significantly decreased in timepoints of 7d after exposure both in SVZ and SGZ regions(P<0.05) of the EMF group;Timeoint of 3d also decreased in SVZ region(P<0.05) in comparison to sham *** results indicated that chronic exposure to 900 MHz EMF(power density:1 mw/cm ) may induce morphological structural changes of cells in the rat SVZ and hippocapus and resulted in learning and memory deficits.
The goal of this study was to investigate the role of phosphatase and tensin homolog deleted on chromosome ten(PTEN) in early brain injury after subarachnoid hemorrhage(SAH).The standard intravascular perforation mode...
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The goal of this study was to investigate the role of phosphatase and tensin homolog deleted on chromosome ten(PTEN) in early brain injury after subarachnoid hemorrhage(SAH).The standard intravascular perforation model was used to produce experimental SAH in Sprague Dawley ***
Inflammation response have been implicated in the pathogenesis of early brain injury after subarachnoid hemorrhage(SAH).Recently,adinosine A3R has attracted attention for its ability to modulate inflammation. In this ...
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Inflammation response have been implicated in the pathogenesis of early brain injury after subarachnoid hemorrhage(SAH).Recently,adinosine A3R has attracted attention for its ability to modulate inflammation. In this study,we investigate whether SAH can induce the activation of astrocyte and microglia and the change
Malignant glioma is the most common and fatal tumor in central nervous system,with the poor prognosis even with the advanced *** new prognostic factors and molecular targets may contribute to the understanding of mali...
Malignant glioma is the most common and fatal tumor in central nervous system,with the poor prognosis even with the advanced *** new prognostic factors and molecular targets may contribute to the understanding of malignance progression and patient ***,we investigated the neurotensin(Nts) expression in a series of 116 patients with gliomas of different histology grades and primary cultured glioma initiating cells(GICs).The correlation between Nts expression and the prognosis was *** effect of NTS expression on GICs proliferation was also *** found that NTS expression was detected in 70.9%of malignant gliomas and was significantly(P=0.015) related with a poor *** analysis indicated that NTS expression(P=0.007) was independent predictors of poor ***,the results revealed that Nts was mainly expressed by GICs,not by differentiated glioma *** of NTS expression resulted in a significant reduction of GICs *** study indicated that the expression of Nts positively correlated with the histology grades of malignances and could be identified as a prognostic marker in patients with *** which are highly expressed in GICs promoted the proliferation of GICs in an autocrine fashion and might be a potential target to restrict self - renewal of GICs.
The use of mobile phone as a most usual radiation emissivesource is so widespread in recent *** biological effects effects of EMFs,particularly on the central nervous system（CNS） have been the subject of a large num...
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The use of mobile phone as a most usual radiation emissivesource is so widespread in recent *** biological effects effects of EMFs,particularly on the central nervous system（CNS） have been the subject of a large number of experimental ***,whether or not these effects are harmful,still remains still controversial.20 - Hydroxyecdysone,which is found in the rhizomes,roots and the stems of many plants,is an ecdysteroid hormone that regulates molting in *** this present study,we investigated the effects of 900 MHz EMF on neural stem cells of Spraque - Dawley（SD） neonatal rat hippocampus in ***,we explored the neuroprtective effects of 20 - Hydroxyecdysone against EMF *** group cells were placed on the exposure platform but not exposed to EMF（power density:0mw/cm,2 h/day for 6 days or consecutive 12h） during the exposure *** groups were exposed to 900 MHz EMF（power density:1 mw/cm or 3 mw/cm,2 h/day for 6 days or consecutive 12h）. For every group,a matching group that was pre - treated with 16mg/L 20 - Hydroxyecdysone before EMF exposure was *** results showed that compared with sham exposure group（Omw/cm）,the ratio of apoptosis and of exposure groups cells were significantly increased（P<0.01 ）,and on condition of intermittent exposure（2h/d,for 6 days）,there were significant differences between the two exposure groups（ P<0.05）,with higher ratio in the 3mw/cm exposure *** exposure groups,in comparison to no-treatment exposure groups,the ratio of apoptosis of pre - treatment exposure groups with 20 - Hydroxyecdysone were obviously decreased（P<0.05）.Futhermore,the cloning efficiency and proliferation of NSCs were significantly reduced in exposure groups（P<0.05 ） and these effects of EMFs were significantly alleviated by 20 - Hydroxyecdysone（P<0.05 ）.Our results indicated that exposure to 900 MHz EMF may induce the apoptosis of neonatal rat hippocampal neural stem cells in vitro in the power -dependent manner.
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