脑肿瘤相关癫痫(BTRE)是脑肿瘤患者常见的并发症,影响生活质量和预后。BTRE的机制涉及神经递质失衡、肿瘤微环境改变和离子通道异常。目前的治疗包括药物、手术、放疗和化疗,但耐药性癫痫和复发仍是挑战。本文总结了BTRE的病理生理机制、诊断评估方法和现有治疗策略。Brain tumor-associated epilepsy (BTRE) is a common complication in patients with brain tumors, affecting their quality of life and prognosis. The mechanism of BTRE involves neurotransmitter imbalance, changes in tumor microenvironment, and abnormal ion channels. The current treatments include medication, surgery, radiation therapy, and chemotherapy, but drug-resistant epilepsy and recurrence remain challenges. This article summarizes the pathophysiological mechanisms, diagnostic evaluation methods, and existing treatment strategies of BTRE.
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