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Quantitative Evaluation of Clinical Efficacy of Laser Thermotherapy for Port-Wine Stains Through Reflectance Spectra Measurements and an Inverse Radiation Algorithm

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Zhongguo Jiguang/Chinese Journal of Lasers 2025年第9期52卷

作者： Li, Dong Li, Xiaoyang Zhang, Pengfei Chen, Bin Ying, Zhaoxia State Key Laboratory of Multiphase Flow in Power Engineering Xi’an Jiaotong University Shaanxi Xi’an710049 China Shaanxi Provincial Institute for Skin Disease and STD Control Shaanxi Xi’an710003 China

Objective Port-wine stains (PWS) are congenital vascular malformations caused by the abnormal dilation of capillaries and venules in the skin. Affecting 0.3%‒0.5% of newborns, PWS typically manifest as pinkish patches on the face and neck that darken and thicken over time, significantly impacting patients’physical and mental well-being. Pulsed dye laser (PDL) therapy, based on selective photothermolysis, is the gold standard for PWS treatment. By targeting hemoglobin in abnormal blood vessels with specific wavelengths, PDL induces thermal damage to the vasculature while sparing surrounding tissues. However, due to variability in skin types, lesion depths, and laser parameters, clinical outcomes often depend on subjective evaluations and physician experience. These limitations underscore the urgent need for objective, quantitative, and noninvasive methods to assess skin structure and monitor treatment efficacy. This study integrates reflectance spectroscopy with an inverse Monte Carlo radiation method to quantify changes in key skin parameters before and after laser treatment. By measuring and reconstructing parameters such as epidermal thickness, melanin volume fraction, blood volume fraction, and blood oxygen saturation, this study establishes a robust framework for evaluating treatment outcomes and optimizing laser parameters. Additionally, it investigates differences in treatment responses between pediatric and adult patients, providing critical insights for personalized therapeutic strategies. Methods Eleven patients with PWS underwent pulsed dye laser (PDL) therapy at a wavelength of 595 nm, with an energy density of 8 J/cm2 and a fixed spot diameter of 7 mm. Reflectance spectra of the skin were measured before and after treatment using an HR400 CG-UV-NIR spectrometer (Fig. 1.. To enhance efficacy, a double-irradiation strategy was employed, in which the second laser exposure followed the first after five minutes. For spectral analysis, an inverse Monte Carlo r

关键词： Hemoglobin oxygen saturation

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Assisting effect of Al_(2)O_(3) on MnO_(x) for NO catalytic oxidation

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Green Energy & Environment 2021年第6期6卷 903-909页

作者： Denghui Wang Hui Li Qi Yao Shien Hui Yanqing Niu State Key Laboratory of Multiphase Flow in Power Engineering School of Energy and Power EngineeringXi'an Jiaotong UniversityXi'an710049China

Various Mn-based catalysts for NO oxidation were prepared using MnO_(x)as active compound,while Ti O_(2)and Al_(2)O_(3)were adopted as catalyst *** performance of the catalysts was tested to study the effect of support on Mn-based catalyst *** of the catalysts followed as Mn_(0.4)/Al>Mn_(0.2)/Al>Mn_(0.4)/Ti>Mn_(0.2)/Ti>MnO_(x)>Al_(2)O_(3)on the whole,indicating the synergism of MnO_(x)and Al_(2)O_(3)for NO catalytic *** were analyzed according to characterization *** oxygen on catalyst rather than lattice oxygen was detected as the active oxidizer for NO *** catalyst support,Al_(2)O_(3)provided more sites to carry surface adsorbed oxygen than TiO_(2),resulting in the presence of more active oxygen on Mn O_(x)/Al_(2)O_(3)than on MnO_(x)/TiO_(2).Moreover,MnO_(x)/Al_(2)O_(3)possessed high surface area and pore volume,which greatly benefited the adsorption of NO on catalyst and further favored the oxidation of NO by active *** these advantages helped Mn_(0.4)/Al exhibited the best catalytic efficiency.

关键词： NO catalytic oxidation MnO_(x)/Al_(2)O_(3) NO_(2) Active oxygen

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Simulation study on mineral transformation behaviors and ash fusion characteristics during high-alkali coal combustion under deep peaking conditions

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Fuel 2025年 399卷

作者： Liu, Jiamiao Ma, Guowei Du, Yongbo Wang, Chang'an Zhao, Yonggang Wu, Wanzhu Shi, Longping Zhao, Lin Che, Defu State Key Laboratory of Multiphase Flow in Power Engineering School of Energy and Power Engineering Xi'an Jiaotong University Xi'an710049 China National Energy Group Science and Technology Research Institute Co. Ltd. Nanjing210046 China Company Xi'an710076 China Huayuan Power Plant National Energy Group Hami Coal Power Co. Ltd. Hami839000 China

The safe and efficient combustion of high-alkali coal under deep peaking conditions remains a critical research focus. Boiler operating parameters under such conditions frequently fluctuate, markedly though incompletely understood in their influence on fouling and slagging, necessitating further investigation. Here, mineral transformation and ash fusion characteristics during high-alkali coal combustion in the main combustion zone were simulated through thermodynamic equilibrium calculations, addressing its fouling issues under deep peaking conditions. Variable loads were decomposed into distinct factors for analysis due to challenges of direct simulation. Additionally, the plasma ashing method was employed to prepare ash samples. High-alkali coals with distinct properties exhibit significant variations in mineral distribution, elemental evolution, ash fusion temperature, and viscosity. Abundant fayalite (Fe2SiO4) was observed in Hongshaquan (HSQ) coal, forming stable mineral phases with other components. In Shaerhu (SEH) coal, sodium primarily exists in the gaseous phase at high temperatures, significantly contributing to fouling. Meanwhile, Jiangjunmiao (JJM) and Wucaiwan (WCW) coals demonstrate limited mineral phases but higher ash fusion temperatures, with over 30 % of iron in the gaseous phase. The mineral transformation and ash fusion behaviors in various local combustion atmospheres follow consistent trends. The formations of gaseous sodium hydroxide (NaOH(g)) and sodium oxide in the slag phase (Na2O(slag)) are promoted with weakening reducing atmospheres, while total gaseous sodium content decreases. The slag phases of calcium, magnesium, and iron increase, accompanied by a decline in ash viscosity. However, unburned carbon inversely influences mineral transformation and ash fusion characteristics compared to excess air coefficients. This research provides theoretical support for overcoming the key technical challenges associated with high-alkali coal combus

关键词： Iron analysis

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Predicting Self-Diffusion Coefficients of Light Gases in Supercritical Carbon Dioxide: A Molecular Dynamics Method

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The Journal of Supercritical Fluids 2025年

作者： Tongjia Zhang Bowei Zhang Jie Zhang Xiaoran Rong Hui Jin State Key Laboratory of Multiphase Flow in Power Engineering Xi’an Jiaotong University Xi’an Shaanxi 710049 PR China

The methanation of CO 2 and supercritical CO 2 (scCO 2 ) fracturing represent effective approaches for CO 2 utilization and greenhouse effect mitigation. In these process, light gases like H 2 , O 2 , CO, CH 4 are commonly involved. However, limited studies have focused on the diffusion behavior of these gases in scCO 2 under high-pressure conditions, as well as a shortage of self-diffusion coefficient data and prediction equations specifically designed for scCO 2 solvents. To address this gap, molecular dynamics (MD) simulations were employed to compute the self-diffusion coefficients of several light gases in scCO 2 across a wide temperature range (31. K–71. K) and at high pressures (75.994 bar, 1.1.325 bar and 1.6.656 bar) under infinitely dilute conditions. The effects of temperature, density, viscosity, molecular mass, and solute–solvent interaction energy on the self-diffusion behavior were systematically analyzed. Two empirical equations (a Speedy–Angell-type power-law equation and a newly developed equation incorporating temperature, density, and viscosity) were refitted based on simulation data. The overall relative errors are 4.52% and 4.44%, respectively, indicating an improved accuracy compared to conventional experimental and MD-based empirical equations.

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Acoustic Wave Prediction in flowing Steam-Water Two-Phase Mixture

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Journal of Thermal Science 1994年第3期3卷 147-154页

作者： Xu Jinliang Chen Tingkuan (state {1. laboratory of multiphase flow in power engineering, Xi’an Jiaotong University, Xi’an 71.049,China) 1. State Key Laboratory of Multiphase Flow in Power Engineering Xi’an Jiaotong University 710049 Xi’an China

The transient two-fluid model has been used to develop a general relation for acoustic waves. The analysis is valid in principle over the whole void fraction region. flow pattern transitions from one flow regime to the other are assumed to occur at certain void fractions. Different correlations are used to calculate the interfacial area and interfacial drag force per unit mixture volume for bubbly flow,slug flow and annular flow respectively. The Vapour-liquid interphase heat flux is derived from the one dimensional Fourier heat conduction equation to evaluate the interphase evaporation or condensatior *** on the present theory, a program has been carried out. Calculations are performed for pressure from 0.07 MPa to 1..0 MPa, void fractions from 0.0 to 1.0. The predicted sound speeds are compare with some experimental data for low pressures, good agreement has been achieved between sound speed predictions and experimental data.

关键词： two-phase flow perturbation wave sound speed

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Characterizations of gas-liquid interface distribution and slug evolution in a vertical pipe

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Petroleum Science 2023年第5期20卷 3157-3171页

作者： Hai-Yang Yu Qiang Xu Ye-Qi Cao Bo Huang Han-Xuan Wang Lie-Jin Guo State Key Laboratory of Multiphase Flow in Power Engineering Xi'an Jiaotong UniversityXi’an710049ShaanxiChina

Large vertical pipes are key structures connecting subsea wells to offshore ***,existing studies mainly focus on small vertical *** a vertical acrylic pipe with 80 mm inner diameter and 1. m height,a high-speed camera was used to visually research the influences of pipe diameters,liquid properties and inlet effect on air-water co-{1. *** {1. regime maps of vertical pipes(diameters are in the range of 50e1.9 mm)were compared and the critical gas velocity of the transition boundary from bubble to slug {1. tended to increase with the increase of diameters at D≥80 ***-flux models were established in different {1. regimes and liquid properties have a significant effect on drift coefficients of bubble {1. and slug {1.(void fraction a≤0.4).The influence of inlet turbulent effect on the gas-liquid interface distribution gradually weakened and disappeared from the pipe base to 85D,where the {1. was fully *** frequency has a trend of increase first and then decrease with the gas Weber numbers increasing at low liquid superficial velocities(J_(L)≤0.31.m/s).And on the basis of this law,a new slug frequency correlation was *** was found that there was an exponential relationship between the ratio of lengths of Taylor bubble to slug and the void fraction.

关键词： Void fraction flow regime Drift coefficien Slug frequency Taylor bubble length

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Cyclone separation in a supercritical water circulating fluidized bed reactor for coallbiomass gasification： Structural design and numerical analysis

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Particuology 2018年第4期16卷 55-67页

作者： Guoxing Li Youjun Lu State Key Laboratory of Multiphase Flow in Power Engineering Xi'an Jiaotong University Xi'an Shaanxi 710049 China

A new concept of a supercritical water （SCW） circulating fiuidized bed reactor is proposed to produce hydrogen from coal/biomass gasification. The cyclone is a key component of the reactor system, in this paper, cyclones with a single circular inlet （SCI） or a double circular inlet （DCI） were designed to adapt to the supercritical conditions. We evaluated the separation performance of the two cyclones using numerical simulations. A three-dimensional Reynolds stress model was used to simulate the turbulent {1. of the fluid, and a stochastic Lagrangian model was used to simulate the particle motion. The {1. fields of both cyclones were three-dimensionally unsteady and similar to those of traditional gas-solid cyclones. Secondary circulation phenomena were discovered and their influence on particle separation was estimated. Analyzing the distribution of the turbulence kinetic energy revealed that the most intensive turbulence existed in the zone near the vortex finder while the {1. in the central part was relatively stable. The particle concentration distribution was non-uniform because of centrifugal forces. The distribution area can be divided into three parts according to the motion of the particles. In addition, the separation efficiency of both cyclones increased with the inlet SCaN velocity. Because of its perturbance {1., the DCI separator had higher separation efficiency than the SCI separator under comparable simulations. However, this was at the expense of a higher pressure drop across the cyclone.

关键词： CycloneStructural design Supercritical water-solid flow Separation performance Circulating fluidized bed Computational fluid dynamics

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Numerical simulation of bubble behavior in a quasi-2D fluidized bed using a bubble-based EMMS model

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Particuology 2019年第5期17卷 40-54页

作者： Hao Wang Youjun Lu State Key Laboratory of Multiphase Flow in Power Engineering Xi’an Jiaotong University Xi'an 710049 Shaanxi China

Bubbles formed during chemical processes in fluidized beds govern the bed hydrodynamics and opera-tional efficiency, thereby having a significant impact on their design and scale-up. In this study, a two-fluid model was used to simulate the bubble behavior in a quasi-two-dimensional fluidized bed within the bubble-based energy minimization multiscale (EMMS) approach. We performed experiments to verify the model and proposed a correlation of the heterogeneous index for various parameters to calculate the coefficient of drag for the bubble-based EMMS model. Moreover, the simulation results obtained from the homogeneous drag models and EMMS bubbling model were compared with experimental data and empirical correlations. The simulation results of the EMMS approach showed good agreement with the experimental data in the distribution of the vertical bubble velocity with chord length. Compared with the results from the homogeneous models, the distributions of vertical velocity and diameter of the bubbles predicted by the EMMS-bubbling model were in better agreement with empirical correlations. Moreover, the frequency distributions of bubble properties including bubble diameter, aspect ratio, and shape factor for different gas-inlet velocities were obtained.

关键词： Energy minimization multi-scale approach Heterogeneous index Fluidized bed Bubble

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Investigation on a Supercritical Water Gasification System with CO_(2)as Transporting Medium

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Journal of Thermal Science 2023年第4期32卷 1614-1625页

作者： WANG Weizuo LU Bingru SHI Jinwen ZHAO Qiuyang JIN Hui State Key Laboratory of Multiphase Flow in Power Engineering(SKLMF) Xi’an Jiaotong UniversityXi’an710049China

As a benign energy vector,hydrogen has been discussed for a long *** water gasification was one of good ways to produce ***,supercritical water gasification system with H_(2)O transporting was energy consuming in the process of heating due to the high specific heat of H_(2)O.A new supercritical water gasification system was established in this paper with supercritical CO_(2)as medium *** plastics were used as the sample transported by CO_(2).Production yields,energy flow and exergy flow of the system were collected and the influence of temperature,pressure,gasification concentration and transporting concentration was *** flow of H_(2)O input into the reactor was 1.00 kg/*** typical condition was as follow:temperature 923.1. K,pressure 23 MPa,and the mass ratio of water,sample and transporting medium was 1.0:9:*** of H_(2),CH4,CO and CO_(2)at this condition was 8.1.kg/h,39.6 kg/h,6.6 kg/h and 1.7.5 kg/h,*** system with H_(2)O transporting was used to compare with the supercritical CO_(2)transporting system and proved that system with CO_(2)transporting could reduce the loss of both energy and exergy while the reduce of each gas production yield was less than 0.1.mol/mol.

关键词： phenolic plastics supercritical water gasification CO_(2)-transporting system energy and exergy flow

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Study on the Enhancement Effect of Dielectric Barrier Discharge on the Premixed Methane/Oxygen/Helium Flame Velocity

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Plasma Science and Technology 2015年第12期17卷 1019-1026页

作者：穆海宝喻琳李平汤成龙王金华张冠军 State Key Laboratory of Electrical Insulation and Power Equipment School of Electrical EngineeringXi'an Jiaotong University State key Laboratory of Multiphase Flow in Power Engineering Xi'an Jiaotong University

Recently,plasma-assisted combustion has become a potentially applicable technology in many combustion *** this paper,a dielectric barrier discharge（DBD） plasma generator is designed to explore the effect of plasma on the CH4 oxidation process,and several properties of combustion are ***,in the presence or absence of plasma discharge,physical appearance of the flame is examined and ***,the flame propagation velocity is calculated by the flame front extracted from the imaging data with the Bunsen burner ***,the main molecular components and their intensity variation in the flame and the plasma zones are identified with an emission spectrograph to analyze the effect of active species on the combustion *** also discuss the possible kinetic regime of plasma-assisted *** results imply that plasma discharge applied to the premixed CH_4/O_2/He mixture significantly raises the flame speed with equivalence ratios ranging from 0.85 to 1.1.,with the flame speed improved by 1.%to 35%.It can be seen that plasma can improve methane oxidation efficiency in the premixed fuel/oxidizer,especially at a low equivalence ratio.

关键词： combustion flame Oxygen equivalence appearance Velocity scenarios burning camera hydrocarbon

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