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Understanding ADC variation by fat content effect using a dual-function MRI phantom

European Radiology Experimental 2024年第1期8卷 19页

作者： Liu, Yi-Jui Tsai, Tung-Sheng Li, Ya-Hui Peng, Jo-Hua Chang, Hing-Chiu Peng, Hsu-Hsia Lee, Ying-Chieh Lee, Tung-Yang Liou, Chang-Hsien Lin, Tz-Feng Chew, Fatt-Yang Chou, Ruey-Hwang Juan, Chun-Jung Department of Automatic Control Engineering Feng Chia University Taichung Taiwan Ph.D. Program in Electrical and Communication Engineering Feng Chia University Taichung Taiwan Department of Medical Imaging China Medical University Hsinchu Hospital 199 Sec. 1 Xinglong Rd. Hsinchu County Zhubei City 302 Taiwan Department of Biomedical Engineering and Environmental Sciences National Tsing Hua University Hsinchu Taiwan Department of Biomedical Engineering Chinese University of Hong Kong Hong Kong Master’s Program of Biomedical Informatics and Biomedical Engineering Feng Chia University Taichung Taiwan Cheng Ching Hospital Taichung Taiwan Institute of Nuclear Engineering and Science National Tsing Hua University Hsinchu Taiwan Department of Fiber and Composite Materials Feng Chia University Taichung Taiwan Department of Medical Imaging China Medical University Hospital Taichung Taiwan Department of Radiology School of Medicine China Medical University Taichung Taiwan Graduate Institute of Biomedical Sciences China Medical University Taichung 406 Taiwan Center for Molecular Medicine China Medical University Hospital Taichung Taiwan Department of Medical Laboratory and Biotechnology Asia University Taichung Taiwan

Background: A dual-function phantom designed to quantify the apparent diffusion coefficient (ADC) in different fat contents (FCs) and glass bead densities (GBDs) to simulate the human tissues has not been documented yet. We propose a dual-function phantom to quantify the FC and to measure the ADC at different FCs and different GBDs. Methods: A fat-containing diffusion phantom comprised by 30 glass-bead-containing fat-water emulsions consisting of six different FCs (0, 10, 20, 30, 40, and 50%) multiplied by five different GBDs (0, 0.1, 0.25, 0.5, and 1.0 g/50 mL). The FC and ADC were measured by the “iterative decomposition of water and fat with echo asymmetry and least squares estimation-IQ,” IDEAL-IQ, and single-shot echo-planar diffusion-weighted imaging, SS-EP-DWI, sequences, respectively. Linear regression analysis was used to evaluate the relationship among the fat fraction (FF) measured by IDEAL-IQ, GBD, and ADC. Results: The ADC was significantly, negatively, and linearly associated with the FF (the linear slope ranged from -0.005 to -0.017, R² = 0.925 to 0.986, all p < 0.001). The slope of the linear relationship between the ADC and the FF, however, varied among different GBDs (the higher the GBD, the lower the slope). ADCs among emulsions across different GBDs and FFs were overlapped. Emulsions with low GBDs plus high FFs shared a same lower ADC range with those with median or high GBDs plus median or lower FFs. Conclusions: A novel dual-function phantom simulating the human tissues allowed to quantify the influence of FC and GBD on ADC. Relevance statement: The study developed an innovative dual-function MRI phantom to explore the impact of FC on ADC variation that can affect clinical results. The results revealed the superimposed effect on FF and GBD density on ADC measurements. Key points: • A dual-function phantom made of glass bead density (GBD) and fat fraction (FF) emulsion has been developed. • Apparent diffusion coefficient (ADC) values

关键词： Adipose tissue Diffusion magnetic resonance imaging Phantoms (imaging) Quality assurance (healthcare) Quality control

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A New Strategic Air Pollution Risk Assessment by Considering the Influence of Wind Regimes

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SSRN 2022年

作者： Santos Silva, Jéssica Caroline dos Potgieter-Vermaak, Sanja Westrupp Medeiros, Sandra Helena da Silva, Luiz Vitor Ferreira, Danielli Ventura Moreira, Camila Ariele Bufato de Souza Zorzenão, Priscila Caroline Pauliquevis, Theotonio Godoi, Ana Flávia Locateli de Souza, Rodrigo Augusto Ferreira Yamamoto, Carlos Itsuo Moreton Godoi, Ricardo Henrique Postgraduate Program in Water Resources and Environmental Engineering Federal University of Paraná Paraná Curitiba Brazil Ecology & Environment Research Centre Department of Natural Science Manchester Metropolitan University ManchesterM1 5GD United Kingdom Molecular Science Institute University of the Witwatersrand Johannesburg South Africa Department of Environmental and Sanitary Engineering University of the Region of Joinville Santa Catarina Joinville Brazil Department of Environmental Engineering Federal University of Paraná Paraná Curitiba Brazil Department of Chemical Engineering Federal University of Paraná Paraná Curitiba Brazil Department of Environmental Sciences Federal University of São Paulo Diadema São Paulo Brazil School of Technology Amazonas State University Amazonas Manaus Brazil

For regulatory purposes, air pollution has been reduced to management of air quality control regions (AQCR), by inventorying pollution sources and identifying the receptors significantly affected. However, beyond being source-dependent, particulate matter can be physically and chemically altered by factors and elements of climate during transport, as they act as local environmental constraints, indirectly modulating the adverse effects of particles on the environment and human health. This case study, at an industrial site in a Brazilian coastal city – Joinville, combines different methodologies to integrate atmospheric dynamics in a strategic risk assessment approach whereby the influence of different wind regimes on environmental and health risks of exposure to PM2.5-bound components, are analysed. Although Joinville AQCR has been prone to stagnation/recirculation events, distinctly different horizontal wind circulation patterns indicate two airsheds within the region. The two sampling sites mirrored these two conditions and as a result we report different PM2.5 mass concentrations, chemical profiles, geo-accumulation, and ecological and human health risks. In addition, feedback mechanisms between the airsheds seem to aggravate the air quality and its effects even under good ventilation conditions. Recognizably, the risks associated with Co, Pb, Ni, Mn, and Zn loadings were extremely high for the environment as well as being the main contributors to elevated non-carcinogenic risks. Meanwhile, higher carcinogenic risks occurred during stagnation/recirculation conditions, with Cr as the major threat. These results highlight the importance of integrating local airshed characteristics into the risk assessment of PM2.5-bound components since they can aggravate air pollution leading to different risks at a granular scale. This new approach to risk assessment can be employed in any city's longer-term development plan since it provides public authorities with a strategic

关键词： Heavy metals

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Dynamic ¹³C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin (vol 23, 100855, 2020)

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Iscience 2020年第12期23卷 100855页

作者： Quek, Lake-Ee Krycer, James R. Ohno, Satoshi Yugi, Katsuyuki Fazakerley, Daniel J. Scalzo, Richard Elkington, Sarah D. Dai, Ziwei Hirayama, Akiyoshi Ikeda, Satsuki Shoji, Futaba Suzuki, Kumi Locasale, Jason W. Soga, Tomoyoshi James, David E. Kuroda, Shinya Charles Perkins Centre The University of Sydney Sydney NSW 2006 Australia School of Mathematics and Statistics The University of Sydney Sydney NSW 2006 Australia Sydney Medical School The University of Sydney Sydney NSW 2006 Australia Department of Biological Sciences Graduate School of Science University of Tokyo Hongo 7-3-1 Bunkyo-ku Tokyo 113-0033 Japan School of Life and Environmental Sciences The University of Sydney Sydney NSW 2006 Australia Institute for Advanced Biosciences Keio University Tsuruoka Yamagata 997-0052 Japan YCI Laboratory for Trans-Omics Young Chief Investigator Program RIKEN Center for Integrative Medical Sciences 1-7-22 Suehiro-cho Tsurumi-ku Yokohama Kanagawa 230-0045 Japan Faculty of Engineering and Information Technologies The University of Sydney Sydney NSW 2006 Australia Department of Pharmacology and Cancer Biology Duke University School of Medicine Duke University Durham NC 27710 USA AMED-CREST AMED 1-7-1 Otemachi Chiyoda-Ku Tokyo 100-0004 Japan Department of Computational Biology and Medical Sciences Graduate School of Frontier Sciences University of Tokyo 5-1-5 Kashiwanoha Kashiwa Chiba 277-8562 Japan CREST Japan Science and Technology Agency Bunkyo-ku Tokyo 113-0033 Japan

Cellular metabolism is dynamic, but quantifying non-steady metabolic fluxes by stable isotope tracers presents unique computational challenges. Here, we developed an efficient 13 C-tracer dynamic metabolic flux analysis (13C-DMFA) framework for modeling central carbon fluxes that vary over time. We used B-splines to generalize the flux parameterization system and to improve the stability of the optimization algorithm. As proof of concept, we investigated how 3T3-L1 cultured adipocytes acutely metabolize glucose in response to insulin. Insulin rapidly stimulates glucose uptake, but intracellular pathways responded with differing speeds and magnitudes. Fluxes in lower glycolysis increased faster than those in upper glycolysis. Glycolysis fluxes rose disproportionally larger and faster than the tricarboxylic acid cycle, with lactate a primary glucose end product. The uncovered array of flux dynamics suggests that glucose catabolism is additionally regulated beyond uptake to help shunt glucose into appropriate pathways. This work demonstrates the value of using dynamic intracellular fluxes to understand metabolic function and pathway regulation.

关键词： Biological sciences Flux Data Metabolomics Metabolic Flux Analysis

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Remediation of an oil-contaminated experimental freshwater wetland: II. Habitat recovery and toxicity reduction

Remediation of an oil-contaminated experimental freshwater w...

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2005 International Oil Spill Conference, IOSC 2005

作者： Lee, Kenneth Doe, Kenneth G. Lee, Lucila E. J. Suidan, Makram T. Venosa, Albert D. Fisheries and Oceans Canada Maurice Lamontagne Institute P.O. Box 1000 Mont-Joli Que. G5H 3Z4 Canada Environmental Science Center Environment Canada P.O. Box 23005 Moncton NB E1A 6S8 Canada Department of Biology Wilfrid Laurier University Waterloo Ont. N2L 3C5 Canada Department of Civil and Environmental Engineering University of Cincinnati 701 ERC Building P.O. Box 210071 Cincinnati OH 45221-0071 National Risk Management Research Laboratory Oil Spill Program U.S. Environmental Protection Agency 26 W. Martin Luther King Drive Cincinnati OH 45268

A controlled oil spill experiment to determine natural recovery rates and the efficacy of potential remediation strategies in wetland ecosystems was initiated in June 1999 at a site on the St. Lawrence River, Canada dominated by Scirpus pungens. A weathered light crude oil (Mesa) was applied on 16 plots (5 m × 4 m) at the rate of 12 L per plot. Treatment of the plots included: natural attenuation (no treatment), nutrient amendment with granular ammonium nitrate and super triple phosphate, a similar treatment with plants continuously cut back (to evaluate the influence of plant growth on remediation), and a nutrient amendment treatment with sodium nitrate instead of ammonium nitrate. To elucidate the effect of nutrient amendments alone, four unoiled plots were fertilized with ammonium nitrate and triple super phosphate. Sediment samples were routinely recovered for chemical and toxicological analysis over a 21-week period that effectively covered the natural growth season of the plants. Significant changes in biological measures of habitat were observed. S. pungens, the dominant plant species, was tolerant to the oil, and its growth was significantly enhanced above that of the unoiled control by the addition of nutrients. Other biotest organisms (bacteria, Vibrio sp.;invertebrates, Daphnia, Hyalella, and Viviparus sp.) provided additional evidence of both enhanced recovery and potential detrimental effects. GC-MS analysis could not resolve significant changes in the composition of the residual oil as a result of experimental treatments. This discrepancy in the detection of treatment efficacy between the chemical and biological methods may be due to induced tolerance to the contaminant hydrocarbons, changes in the bioavailability of the residual oil associated with stimulated plant growth, and detrimental effects of the type and quantity of bioremediation agents used.

关键词： Wetlands

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The role of input imaging combination and ADC threshold on segmentation of acute ischemic stroke lesion using U-Net

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European Radiology 2023年第9期33卷 6157-6167页

作者： Li, Ya-Hui Lin, Shao-Chieh Chung, Hsiao-Wen Chang, Chia-Ching Peng, Hsu-Hsia Huang, Teng-Yi Shen, Wu-Chung Tsai, Chon-Haw Lo, Yu-Chien Lee, Tung-Yang Juan, Cheng-Hsuan Juan, Cheng-En Chang, Hing-Chiu Liu, Yi-Jui Juan, Chun-Jung Graduate Institute of Biomedical Electronics and Bioinformatics National Taiwan University Taipei Taiwan Department of Medical Imaging China Medical University Hsinchu Hospital No. 199 Sec. 1 Xinglong Rd. Zhubei City Hsinchu County 302 Hsinchu Taiwan Ph.D. Program in Electrical and Communication Engineering Feng Chia University Taichung Taiwan Department of Electrical Engineering National Taiwan University Taipei Taiwan Department of Management Science National Yang Ming Chiao Tung University Hsinchu Taiwan Department of Biomedical Engineering and Environmental Sciences National Tsing Hua University Hsinchu Taiwan Department of Electrical Engineering National Taiwan University of Science and Technology Taipei Taiwan Department of Radiology School of Medicine College of Medicine China Medical University Taichung Taiwan Department of Medical Imaging Medical University Hospital Taichung Taiwan Department of Neurology China Medical University Hospital Taichung Taiwan Cheng Ching Hospital Taichung Taiwan Master’s Program of Biomedical Informatics and Biomedical Engineering Feng Chia University Taichung Taiwan Department of Automatic Control Engineering Feng Chia University No. 100 Wenhwa Rd. Seatwen Taichung 40724 Taiwan Department of Biomedical Engineering The Chinese University of Hong Kong ERB1112 11/F William M.W. Mong Engineering Building N.T Shatin Hong Kong Multi-Scale Medical Robotics Center The Chinese University of Hong Kong N.T Shatin Hong Kong Department of Biomedical Engineering National Defense Medical Center Taipei Taiwan Department of Computer Science and Information Engineering National Taiwan University Taipei Taiwan

Background: To evaluate the effect of the weighting of input imaging combo and ADC threshold on the performance of the U-Net and to find an optimized input imaging combo and ADC threshold in segmenting acute ischemic stroke (AIS) lesion. Methods: This study retrospectively enrolled a total of 212 patients having AIS. Four combos, including ADC-ADC-ADC (AAA), DWI-ADC-ADC (DAA), DWI-DWI-ADC (DDA), and DWI-DWI-DWI (DDD), were used as input images, respectively. Three ADC thresholds including 0.6, 0.8 and 1.8 × 10^–3 mm²/s were applied. Dice similarity coefficient (DSC) was used to evaluate the segmentation performance of U-Nets. Nonparametric Kruskal–Wallis test with Tukey–Kramer post-hoc tests were used for comparison. A p <.05 was considered statistically significant. Results: The DSC significantly varied among different combos of images and different ADC thresholds. Hybrid U-Nets outperformed uniform U-Nets at ADC thresholds of 0.6 × 10^–3 mm²/s and 0.8 × 10^–3 mm²/s (p <.001). The U-Net with imaging combo of DDD had segmentation performance similar to hybrid U-Nets at an ADC threshold of 1.8 × 10^–3 mm²/s (p =.062 to 1). The U-Net using the imaging combo of DAA at the ADC threshold of 0.6 × 10^–3 mm²/s achieved the highest DSC in the segmentation of AIS lesion. Conclusions: The segmentation performance of U-Net for AIS varies among the input imaging combos and ADC thresholds. The U-Net is optimized by choosing the imaging combo of DAA at an ADC threshold of 0.6 × 10^–3 mm²/s in segmentating AIS lesion with highest DSC. Key Points: • Segmentation performance of U-Net for AIS differs among input imaging combos. • Segmentation performance of U-Net for AIS differs among ADC thresholds. • U-Net is optimized using DAA with ADC = 0.6 × 10^–3mm²/s. © 2023, The Author(s), under exclusive licence to European Society of Radiology.

关键词： Deep Learning Diffusion Magnetic Resonance Imaging Ischemic Stroke Neural Networks, Computer Retrospective Study

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"what We Breathe Impacts Our Health: Improving Understanding of the Link between Air Pollution and Health"

"what We Breathe Impacts Our Health: Improving Understanding...

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作者： West, J. Jason Cohen, Aaron Dentener, Frank Brunekreef, Bert Zhu, Tong Armstrong, Ben Bell, Michelle L. Brauer, Michael Carmichael, Gregory Costa, Dan L. Dockery, Douglas W. Kleeman, Michael Krzyzanowski, Michal Künzli, Nino Liousse, Catherine Lung, Shih-Chun Candice Martin, Randall V. Pöschl, Ulrich Pope, C. Arden Roberts, James M. Russell, Armistead G. Wiedinmyer, Christine Environmental Sciences and Engineering University of North Carolina at Chapel Hill Chapel HillNC27599 United States Health Effects Institute BostonMA02110 United States European Commission Joint Research Centre Institute for Environment and Sustainability IspraI. 21027 Italy Institute for Risk Assessment Sciences Universiteit Utrecht Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Utrecht3584 CJ Netherlands State Key Lab for Environmental Simulation and Pollution Control College of Environmental Science and Engineering Peking University Beijing100871 China Social and Environmental Health Research London School of Hygiene and Tropical Medicine LondonWC1E 7HT United Kingdom School of Forestry and Environmental Studies Yale University New HavenCT06511 United States School of Population and Public Health University of British Columbia VancouverBCV6T 1Z3 Canada Chemical and Biochemical Engineering University of Iowa Iowa CityIA52242 United States Air Climate and Energy Research Program Office of Research and Development Environmental Protection Agency DurhamNC27705 United States Harvard T. H. Chan School of Public Health BostonMA02115 United States Civil and Environmental Engineering University of California at Davis DavisCA95616 United States Environmental Research Group King's College London LondonSE1 9NH United Kingdom Epidemiology and Public Health Swiss Tropical and Public Health Institute Basel Switzerland University of Basel Basel Switzerland Laboratoire d' Aérologie CNRS-Université de Toulouse Toulouse31400 France Research Center for Environmental Changes Academia Sinica Taipei Taiwan Physics and Atmospheric Science Dalhousie University HalifaxNSB3H 4R2 Canada Harvard-Smithsonian Center for Astrophysics CambridgeMA02138 United States Multiphase Chemistry Department Max Planck Institute for Chemistry Mainz55128 Germany Economics Brigham Young University ProvoUT84602 United States Ea

Air pollution contributes to the premature deaths of millions of people each year around the world, and air quality problems are growing in many developing nations. While past policy efforts have succeeded in reducing particulate matter and trace gases in North America and Europe, adverse health effects are found at even these lower levels of air pollution. Future policy actions will benefit from improved understanding of the interactions and health effects of different chemical species and source categories. Achieving this new understanding requires air pollution scientists and engineers to work increasingly closely with health scientists. In particular, research is needed to better understand the chemical and physical properties of complex air pollutant mixtures, and to use new observations provided by satellites, advanced in situ measurement techniques, and distributed micro monitoring networks, coupled with models, to better characterize air pollution exposure for epidemiological and toxicological research, and to better quantify the effects of specific source sectors and mitigation strategies. © 2016 American Chemical Society.

关键词： Health

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Z-scheme S, B co-doped g-C3N4 nanotube@MnO2 heterojunction with visible-light-responsive for enhanced photodegradation of diclofenac by peroxymonosulfate activation

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Chemical engineering Journal 2023年 452卷

作者： Dung Nguyen, Manh Binh Nguyen, Thanh Hai Tran, Linh Giang Nguyen, Thuy Fatimah, Is Prasetyo Kuncoro, Eko Doong, Ruey-An Department of Biomedical Engineering and Environmental Sciences National Tsing Hua University Hsinchu30013 Taiwan Institute of Aquatic Science and Technology National Kaohsiung University of Science and Technology Kaohsiung City81157 Taiwan Center of Crop Research for Adaptation to Climate Change Thai Nguyen University of Agriculture and Forestry Quyet Thang Ward Thai Nguyen City Viet Nam Department of Chemistry Faculty of Mathematics and Natural Science Universitas Islam Indonesia Kampus Terpadu UII J1. Kaliurang Km 14 Sleman Yogyakarta Indonesia Environmental Engineering Program Faculty of Science and Technology University of Airlangga Surabaya60115 Indonesia Institute of Analytical and Environmental Sciences National Tsing Hua University 101 Sec. 2 Kuang Fu Road Hsinchu30013 Taiwan

In this study, the manganese dioxide (MnO2) nanosheets were successfully embedded onto boron and sulfur co-doped g-C3N4 (CNBS) nanotubes to construct the flower-like core–shell CNBS@MnO2 heterojunction with Z-scheme structure for the enhanced photodegradation of diclofenac (DCF) in the presence of peroxymonosulfate (PMS) and 460-nm visible light. The CNBS@MnO2 provides large specific surface area and reduced interfacial resistance for rapid electron transport. Moreover, the redox cycling of Mn species effectively activates PMS to produce sulfate radicals for DCF photodegradation. The PMS-based photodegradation of DCF over CNBS@MnO2 displays the excellent photodegradation performance after 15 min of irradiation, and the efficiency is highly dependent on initial pH, ion species, and concentrations of PMS and DCF. The CNBS@MnO2 also shows its excellent stability and reusability over ten cycles. Besides, h+, O2●− and SO4●− are the dominantly reactive species for the enhanced degradation of DCF over Z-scheme CNBS@MnO2 heterojunction. The possible reaction mechanism as well as the degradation pathway of DCF over CNBS@MnO2 in the presence of PMS is also proposed. Results clearly highlight the superior photoactivity of Z-scheme CNBS@MnO2 toward micropollutant degradation by PMS activation, which can open an avenue to fabricate the g-C3N4 nanotube@metal oxide structure as an effective activator for water and wastewater purification. © 2022 Elsevier B.V.

关键词： Heterojunctions

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Cyclodextrin-Modified Layered Double Hydroxide Thin-Film Nanocomposite Desalination Membrane for Boron Removal

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SSRN 2023年

作者： Ee, Liang Ying Zhao, Qipeng Gao, Jie Lim, Chit Kai Xue, Kai Chin, Sze Yuet Li, Sam Fong Yau Chung, Tai-Shung Chen, Shing Bor Department of Chemical and Biomolecular Engineering College of Design and Engineering National University of Singapore 4 Engineering Drive 4 Singapore117585 Singapore Department of Chemistry College of Humanities and Sciences National University of Singapore 3 Science Drive 3 Singapore117543 Singapore Chemical Engineering Program Physical Science and Engineering Division King Abdullah University of Science and Technology Thuwal23955-6900 Saudi Arabia Centre of High Field NMR Spectroscopy and Imaging School of Physical and Mathematical Sciences College of Science Nanyang Technological University 21 Nanyang Link Singapore637371 Singapore NUS Environmental Research Institute National University of Singapore T-Lab Building 5A Engineering Drive 1 Singapore117411 Singapore Graduate Institute of Applied Science and Technology National Taiwan University of Science and Technology Taipei106335 Taiwan

The elimination of small and potentially toxic boron species in water is always a significant challenge for conventional membrane technologies. In this study, facile intercalation and functionalization of β-cyclodextrin (CD) onto layered double hydroxides (LDHs) have resulted in the formation of accessible hydroxyl functional groups and anions that exhibit strong sorption with boron. Through meticulous molecular design and optimization, the modified LDH possessing the maximum boron adsorption capacity of 96.1 mg g-1 was employed to fabricate a polyamide-based thin-film nanocomposite (TFN) membrane with a loading of 0.10 wt.%. This resultant membrane displayed a high salt rejection and water permeance of 99.4 % and 2.68 LMH bar-1 for brackish water, respectively, which can be attributed to the increased interlayer spacing of 1.67 nm and the thinner selective layer. The innovative TFN membrane also achieved a high boron rejection of 82.3 % against brackish water containing 2,000 mg L-1 NaCl and 15 mg L-1 B at pH 8. This pioneering study provides valuable insights into the design of brackish water reverse osmosis (BWRO) membranes, through the synergistic use of macrocyclic molecules and inorganic layered nanomaterials, that could potentially revolutionize water reuse and boron removal applications. © 2023, The Authors. All rights reserved.

关键词： Sodium chloride

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Back-arc basin closure at the East Asian margin during Permo-Triassic boundary: Evidence from geochemistry and U-Pb zircon data of sedimentary breccia from Maizuru Terrane, Southwest Japan

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Geosystems and Geoenvironment 2022年第3期1卷

作者： Ngombi Mavoungou, Larissa Das, Kaushik Kawaguchi, Kenta Hayasaka, Yasutaka Shibata, Tomoyuki Earth and Planetary Systems Science Program Graduate School of Advanced Science and Engineering Hiroshima University 1-3-1 Kagamiyama Higashi-Hiroshima Hiroshima 739-8526 Japan Hiroshima Institute of Plate Convergence Region Research 1-3-1 Kagamiyama Higashi-Hiroshima Hiroshima 739-8526 Japan Department of Earth and Environmental Sciences Jeonbuk National University 567 Baekje-daero Deokjin-gu Jeonju Jeollabuk-do 54896 South Korea

The paleo Maizuru back-arc basin, which was located at the East Asian continental margin opened in Early Permian times and closed during the Permo-Triassic (P-T) boundary. The back-arc basin sediments are exposed in the present-day Maizuru Terrane located in Southwest Japan and hold the key to understand the tectonic evolution of both this back-arc basin and that of the East Asian continental margin. The opening of the Maizuru back-arc basin was accompanied by the deposition of a massive black mudstone-dominated formation, presently recognized as the Maizuru Group. The closure of the back-arc basin which was accompanied by the deposition of coarse-grained materials such as the Tonoshiki breccia made up of differently-sized extremely angular clasts implies that the P-T boundary was a tectonically active period in the Maizuru Terrane. Petrographical and geochemical studies revealed that Tonoshiki breccia can be divided into two main types, a first type mainly made up of mafic to intermediate rock clast fragments (Type I) and a second type mostly consisting of felsic rock clast materials (Type II). Both types commonly contain massive black mudstone clasts that were derived from the underlying Maizuru Group. The U-Pb detrital zircon geochronology of those two types of breccia suggests that they were deposited during two phases of the tectonic activity-induced debris flow that occurred at ca. 259 Ma and ca. 251 Ma for the first and second type, respectively. Type I was sourced from the Southern zone, whereas Type II was sourced mostly from the Northern zone of the Maizuru Terrane. This switch of provenance testifies to the intense tectonic activity that reigned during the P-T boundary. The closure of the Maizuru back-arc basin was induced by the subduction of the basement crust of the basin under the East-Asian continent during the P-T boundary. © 2022 The Authors

关键词： Back-arc basin closure Geochemistry Maizuru Terrane Permo-Triassic boundary Tonoshiki breccia U-Pb zircon age

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Interaction between Nanofibrillated Cellulose (Nfc) and Portland Cement Mortars Subjected to Alkali-Aggregate Reaction (Aar)

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SSRN 2024年

作者： Farias, Marcelo Miranda Pereira, Eduardo de Melo Carvalho, Benjamim Goncalves, Jose de Medeiros, Marcelo Henrique Farias Graduate Program in Materials Science and Engineering State University of Ponta Grossa Avenida Carlos Cavalcanti 4748 Uvaranas Ponta GrossaCEP: 84030-900 Brazil Department of Civil and Environmental Engineering The University of Alberta EdmontonABT6G 1H9 Canada Department of Civil Construction – Polytechnical Center Paraná CuritibaCEP: 81.530-000 Brazil

HIGHLIGHTS• NFC can increase the compressive strength of cement pastes by up to 59%.• NFC degrades in the pore solution of mortars after 60 days of curing;• NFC degradation reduces the tensile strength of cement pastes and mortars;• NFC can mitigate the effects of alkali-aggregate reaction in mortars;• NFC fibers act as a "stress reserve" in expansive mechanisms caused by AAR. © 2024, The Authors. All rights reserved.

关键词： Mortar

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