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HCVMultiscaleDyn: A simulator for the multiscale model of hepatitis C virus dynamics

AIP Conference Proceedings 2018年第1期1978卷

作者： Alexander Churkin Vladimir Reinharz Harel Dahari Danny Barash 1Department of Software Engineering Shamoon College of Engineering Beer-Sheva Israel 2Department of Computer Science Ben-Gurion Universty Beer-Sheva Israel 3The Program for Experimental and Theoretical Modeling Division of Hepatology Department of Medicine Loyola University Medical Center Maywood Illinois USA

Multiscale mathematical models that incorporate both intracellular and extracellular hepatitis C virus (HCV) dynamics have been developed in recent years to study HCV-host dynamics and antivirals mode of action and efficacy. They were built upon the standard HCV dynamic model that keeps track of uninfected hepatocytes, HCV-infected hepatocytes, and free virus in blood (for each there is a differential equation), along with a fourth equation that considers the intracellular viral RNA (vRNA) dynamics in an infected cell. A multiscale model with vRNA dynamics consideration is substantially more difficult to solve and the governing differential equations are stiff. In one of the derived differential equations there is also an integral involving the vRNA that is more accurately computed by considering previous iterations, impeding the use of canned solvers. To solve this problem we have chosen to implement a stable and efficient numerical method that belongs to the family of adaptive stepsize methods and is implicit, the Rosenbrock method. We provide a user friendly simulator called HCVMultiscaleDyn with a Graphical User Interface that applies this method and is useful to simulate viral dynamics during antiviral treatment.

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Study of some network parameters for chalcogenide glasses at an average coordination number 2.4

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AIP Conference Proceedings 2018年第1期2050卷

作者： Rajan Sharma Ekta Sharma Pradeep K. Singh Pankaj Sharma 1Department of Physics & Materials Science Jaypee University of Information Technology Waknaghat Solan - 173234 India 2Computer Science & Engineering and Information Technology Jaypee University of Information Technology Waknaghat Solan - 173234 India

In the study of glassy network state interest among the experimenters and theorists is appraised in the analysis of structurally tangled state. Through a discussion of topological model, which are acquired to understand the atomic arrangement in the glass network we can recognise the technological relevance of chalcogenide glasses. Chalcogenide glasses relate to the (SnSe4)95-x (Bi2Te3)5+x (x = 0, 5, 15, 25, 35, 45 at %) alloy have been investigated for theoretical parameters. Based on average coordination number and the bond energies one should have estimated the average number of nearest neighbour of each type expected to embrace a given central atom. Using average coordination number the various network parameters viz. bond stretching constant (Nα), bond bending constant (Nβ), total number of constraint per atom (Nc), lone pair of electron (L), of the glass alloy have been examined theoretically. Lone pair electron (L) value are found to be constant throughout the compositions as L value comes out to be greater than 3 indicates that alloy can retain their vitreous *** total number of constraint per atom (Nc) were calculated in the light of most stable composition which shows the best conditions for the glass formation.

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Simple security proof of twin-field type quantum key distribution protocol

arXiv

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arXiv 2018年

作者： Curty, Marcos Azuma, Koji Lo, Hoi-Kwong Escuela de Ingeniería de Telecomunicación Dept. of Signal Theory and Communications University of Vigo VigoE-36310 Spain NTT Basic Research Laboratories NTT Corporation 3-1 Morinosato Wakamiya Atsugi Kanagawa243-0198 Japan NTT Research Center for Theoretical Quantum Physics NTT Corporation 3-1 Morinosato Wakamiya Atsugi Kanagawa243-0198 Japan Center for Quantum Information and Quantum Control Department of Electrical & Computer Engineering Department of Physics University of Toronto TorontoONM5S 3G4 Canada

Twin-field (TF) quantum key distribution (QKD) was conjectured to beat the private capacity of a point-to-point QKD link by using single-photon interference in a central measuring station. This remarkable conjecture has recently triggered an intense research activity to prove its security. Here, we introduce a TF-type QKD protocol which is conceptually simpler than the original proposal. It relies on local phase randomization, instead of global phase randomization, which significantly simplifies its security analysis and is arguably less demanding experimentally. We demonstrate that the secure key rate of our protocol has a square-root improvement over the point-to-point private capacity, as conjectured by the original TF-QKD scheme. Copyright © 2018, The Authors. All rights reserved.

关键词： Quantum cryptography

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High performance supercapacitor from activated carbon derived from waste orange skin

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AIP Conference Proceedings 2018年第1期1953卷

作者： Sultan Ahmed S. Hussain Ahsan Ahmed M. Rafat 1Department of Applied Sciences and Humanities Faculty of Engineering Jamia Millia Islamia New Delhi India 2Deptt. of Electrical Engineering Faculty of Engineering Jazan University Jazan KSA Saudi Arabia 3College of Computer and Information Sciences Majmaah University KSA Saudi Arabia

Activated carbon due to its inherent properties such as large surface area and low cost is most frequently used electrode material for supercapacitor. Activated carbon has been previously derived from various biomass such as coconut shell, coffee bean etc. Herein, we report the synthesis of activated carbon from waste orange skin. The material was synthesized employing chemical activation method and the success of synthesis was confirmed by its physical and electrochemical properties. The physical properties of the as-prepared sample were studied using the techniques of XRD, SEM, Raman spectroscopy and N2 adsorption/desorption analysis while its electrochemical properties were studied in two-electrode assembly using liquid electrolyte (consisting of 1 M solution of LiTFSI dispersed in ionic liquid EMITFSI) and employing the techniques of cyclic voltammetry, electrochemical impedance spectroscopy and galvanostatic charge- discharge. The synthesized sample of activated carbon exhibits high specific capacitance of 115 F g-1 at 10 mV s−1. Also, the activated carbon electrode shows the retention of ∼75% in initial capacitance value for more than 2000 initial cycles, indicating the as-prepared activated carbon can be profitably used as electrode material for energy storage devices.

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The application of ROV (remotely operated vehicle) of the microcontroller submarine as a tool to take sample of water and soil contaminated by waste

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AIP Conference Proceedings 2019年第1期2088卷

作者： Muhammad Syukron Nuralif Mardiyah Wahono Ahmad Rosikhin Zamah Sari 1Department of Computer Science Faculty of Engineering Universitas Muhammadiyah Malang Jalan Raya Tlogomas No. 246 Tlogomas Lowokwaru Tegalgondo Karangploso Malang Jawa Timur 65144 Indonesia 2Department of Agro technology Faculty of Agriculture and Animal Husbandry Universitas Muhammadiyah Malang Jalan Raya Tlogomas No. 246 Tlogomas Lowokwaru Tegalgondo Karangploso Malang Jawa Timur 65144 Indonesia 3Department of Physics Institut Teknologi Bandung Jl. Ganesha No.10 Lb. Siliwangi Coblong Kota Bandung Jawa Barat 40132 Indonesia

This paper describes ROV (Remotely Operated Vehicle) that can take sample of contaminated water and soil while the operator operates it on the shore or ship. User can operate ROV wirelessly. ROV is equipped with camera, robot hand, GPS, accelerometer, compass, and other devices. The ROV is aimed to help researchers to research contaminated water and soil that can be applied in and on the lake, river, and sea. The way it operates are syphoning water with mini pump and taking soil sample with robot hand. The result shows that all hardware and software can run well underwater. So that, ROV in this experiment can be used to take sample of contaminated water and soil in the place with maximum a depth of 1m. For the next experiment, this ROV will be tested in other place with a depth more than 1m. however, this ROV will continue to be refined to be maximally utilized.

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Persistence border collisions in a vibrating system excited by an unbalanced motor with a relay control

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AIP Conference Proceedings 2018年第1期1959卷

作者： Zhanybai T. Zhusubaliyev Viktor Avrutin Vasily G. Rubanov Dmitry A. Bushuev Dmitry V. Titov Olga O. Yanochkina 1Department of Computer Science Southwest State University 50 Years of October Str. 94 305040 Kursk Russia 2Institute for Systems Theory and Automatic Control University of Stuttgart Pfaffenwaldring 9 70550 Stuttgart Germany 3Department of Engineering Cybernetics Belgorod State Technological University Kostyukov Str. 46 308012 Belgorod Russia

The paper describes a new scenario for the transition to complex dynamics in a vibrating system with an unbalanced rotor and a relay feedback control. We show that the transition from a regular dynamics without switching events in the relay element to an irregular dynamics which takes place completely in the hysteresis region occurs via a cascade of persistence border collisions.

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control of Synchronization Regimes in Networks of Mobile Interacting Agents

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Physical Review Applied 2017年第5期7卷 054002-054002页

作者： Fernando Perez-Diaz Ruediger Zillmer Roderich Groß Department of Computer Science The University of Sheffield Sheffield S1 4DP United Kingdom Unilever R&D Port Sunlight CH63 3JW United Kingdom Department of Automatic Control and Systems Engineering The University of Sheffield Sheffield S1 3JD United Kingdom

We investigate synchronization in a population of mobile pulse-coupled agents with a view towards implementations in swarm-robotics systems and mobile sensor networks. Previous theoretical approaches dealt with range and nearest-neighbor interactions. In the latter case, a synchronization-hindering regime for intermediate agent mobility is found. We investigate the robustness of this intermediate regime under practical scenarios. We show that synchronization in the intermediate regime can be predicted by means of a suitable metric of the phase response curve. Furthermore, we study more-realistic K-nearest-neighbor and cone-of-vision interactions, showing that it is possible to control the extent of the synchronization-hindering region by appropriately tuning the size of the neighborhood. To assess the effect of noise, we analyze the propagation of perturbations over the network and draw an analogy between the response in the hindering regime and stable chaos. Our findings reveal the conditions for the control of clock or activity synchronization of agents with intermediate mobility. In addition, the emergence of the intermediate regime is validated experimentally using a swarm of physical robots interacting with cone-of-vision interactions.

关键词： Complex systems Swarming Synchronization Coupled oscillators Dynamical systems Evolving networks

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Quantum key distribution with setting-choice-independently correlated light sources

arXiv

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arXiv 2018年

作者： Mizutani, Akihiro Kato, Go Azuma, Koji Curty, Marcos Ikuta, Rikizo Yamamoto, Takashi Imoto, Nobuyuki Lo, Hoi-Kwong Tamaki, Kiyoshi Graduate School of Engineering Science Osaka University Toyonaka Osaka560-8531 Japan NTT Communication Science Laboratories NTT Corporation 3-1 Morinosato Wakamiya Atsugi-Shi Kanagawa243-0198 Japan NTT Research Center for Theoretical Quantum Physics NTT Corporation 3-1 Morinosato-Wakamiya Atsugi Kanagawa243-0198 Japan NTT Basic Research Laboratories NTT Corporation 3-1 Morinosato-Wakamiya Atsugi-Shi243-0198 Japan EI Telecomunicacion Department of Signal Theory and Communications University of Vigo VigoE-36310 Spain Center for Quantum Information and Quantum Control Department of Physics and Dept. of Electrical and Computer Engineering University of Toronto TorontoM5S 3G4 Canada Graduate School of Science and Engineering for Education University of Toyama Gofuku 3190 Toyama930-8555 Japan

Despite the enormous theoretical and experimental progress made so far in quantum key distribution (QKD), the security of most existing QKD implementations is not rigorously established yet. A critical obstacle is that almost all existing security proofs make ideal assumptions on the QKD devices. Problematically, such assumptions are hard to satisfy in the experiments, and therefore it is not obvious how to apply such security proofs to practical QKD systems. Fortunately, any imperfections and security-loopholes in the measurement devices can be perfectly closed by measurement-device-independent QKD (MDI-QKD), and thus we only need to consider how to secure the source devices. Among imperfections in the source devices, correlations between the sending pulses are one of the principal problems. In this paper, we consider a setting-choice-independent correlation (SCIC) framework in which the sending pulses can present arbitrary correlations but they are independent of the previous setting choices such as the bit, the basis and the intensity settings. Within the framework of SCIC, we consider the dominant uctuations of the sending states, such as the relative phases and the intensities, and provide a self-contained information theoretic security proof for the loss-tolerant QKD protocol in the finite-key regime. We demonstrate the feasibility of secure quantum communication within a reasonable number of pulses sent, and thus we are convinced that our work constitutes a crucial step toward guaranteeing implementation security of QKD. Copyright © 2018, The Authors. All rights reserved.

关键词： Quantum cryptography

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Geometrical mass-inertia model of dynamic surface forming

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AIP Conference Proceedings 2018年第1期2007卷

作者： K. L. Panchuk D. S. Korchagin I. V. Krysova 1Department of Engineering Geometry and CAD Faculty of Information Technologies and Computer Systems Omsk State Technical University Mira Ave. 11 Omsk 644050 Russia 2Design department Omsk Scientific Research Institute of Instrument Engineering Maslennikov St. 231 Omsk 644009 Russia

Dependence of the elements of inertia tensor on the area of cross-section bounded by a generatrix of a dynamic surface is determined. Their dependence on the area of dynamic parameters describing the flow of the working medium, such as flow rate, average flow velocity through cross section, the flow power in the cross section, etc., is determined as well. Studies have shown that the inertia tensor contains geometric information concerning the generatrix and can be used for shaping the channel surface in accordance with dynamic parameters of the working medium. A geometric model of dynamic surface formation based on the application of mass-inertia characteristics of its generatrixes is obtained. The conducted research allows to achieve the most optimal combination of regime (dynamic) characteristics of the working medium transported by the dynamic surface and the design characteristics of such surface.

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Optimization of printing techniques for electrochemical biosensors

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AIP Conference Proceedings 2017年第1期1808卷

作者： Ahmad Anwar Zainuddin Ahmad Fairuzabadi Mohd Mansor Rosminazuin Ab Rahim Anis Nurashikin Nordin 1Department of Electrical and Computer Engineering Kulliyyah of Engineering IIUM Kuala Lumpur Malaysia

Electrochemical biosensors show great promise for point-of-care applications due to their low cost, portability and compatibility with microfluidics. The miniature size of these sensors provides advantages in terms of sensitivity, specificity and allows them to be mass produced in arrays. The most reliable fabrication technique for these sensors is lithography followed by metal deposition using sputtering or chemical vapor deposition techniques. This technique which is usually done in the cleanroom requires expensive masking followed by deposition. Recently, cheaper printing techniques such as screen-printing and ink-jet printing have become popular due to its low cost, ease of fabrication and mask-less method. In this paper, two different printing techniques namely inkjet and screen printing are demonstrated for an electrochemical biosensor. For ink-jet printing technique, optimization of key printing parameters, such as pulse voltages, drop spacing and waveform setting, in-house temperature and cure annealing for obtaining the high quality droplets, are discussed. These factors are compared with screen-printing parameters such as mesh size, emulsion thickness, minimum spacing of lines and curing times. The reliability and reproducibility of the sensors are evaluated using scotch tape test, resistivity and profile-meter measurements. It was found that inkjet printing is superior because it is mask-less, has minimum resolution of 100 µm compared to 200 µm for screen printing and higher reproducibility rate of 90% compared to 78% for screen printing.

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