检索结果-内蒙古大学图书馆

Environmental Management 1977年第1期1卷 67-96页

作者： Frankenfeld, John W. Schulz, Wolfgang McMurty, George J. Petersen, Gary W. May, G. A. Hering, F. S. Schwartz, J. I. Heywood, J. B. Chigier, N. A. Grohse, E. W. Walker, J. D. Colwell, R. R. Petrakis, L. Pergament, H. S. Thorpe, R. D. Schoepf, Richard W. Krzyczkowski, Roman Henneman, Suzanne S. Hudson, Charles L. Putnam, Evelyn S. Thiesen, Donna J. Parks, G. A. McCarty, Perry L. Leckie, J. O. Schrumpf, Barry J. Simonson, G. H. Paine, D. P. Lawrence, R. D. Pyott, W. T. Leh, M. Elders, W. Combs, J. Caplen, T. Harrison, F. L. Wong, K. M. Heft., R. E. Charnell, Robert L. Lehmann, Edward J. Mallon, Lawrence G. Hatfield, Cecile Adams, Gerald H. Johanning, James Talvitie, Antti Noll, Kenneth E. Miller, Terry Smiarowski, Joseph F. Willis, Cleve E. Foster, John H. Schlesinger, Benjamin Daetz, Douglas Lear, Donald U. Smith, Mona F. Hundemann, Audrey S. Crockett, Pernell W. Werner, Kirk G. Carroll, Thomas E. Maase, David L. Genco, Joseph E. Ifeadi, Christopher N. Lowman, F. G. Christensen, S. W. Van Winkle, W. Mattice, J. S. Harrison, Elizabeth A. Barker, James C. Chesness, Jerry L. Smith, Ralph E. Shaheeen, Donald G. Raney, R. Keith Borton, T. Wezernak, C. T. Raney, R. K. Sherwani, Jabbor K. Moreau, David H. Eisenberg, Norman A. Lynch, Cornelius J. Breeding, Roger J. Johnson, J. D. Foster, K. E. Mouat, D. A. Clark, R. Hyden, John William Owen, Wilfred Bayfield, Neil G. Barrow, Graham C. Stolz, Stephanie B. Wienckowski, Louis A. Brown, Betram S. Keyfitz, Nathan Wilson, W. L. Newman, Peter W. G. Bammi, Deepak Bammi, Dalip Goddard, James E. Chisholm, Tony Walsh, Cliff Brennan, Geoffrey Thompson, K. S. Richardson, R. Jensen, Clayton E. Brown, Dail W. Mirabito, John A. Cowing, Thomas G. Binghamton, Suny Siehl, George H. Albrecht, O. W. Alexander, Ariel Barde, Jean -Philippe Darby, William P. McMichael, Francis Clay Dunlap, Robert W. Muckleston, Keith W. Frankenhoff, Charles A. Giulini, Lorenzo T. Wyatt, T. Black, Peter E. Keating, William Thomas Leonard, M. E. Fisher, E. L. Brunelle, M. F. Dickinson, J. E. Pethig, Rudiger Clapham Exxon Research & Engineering Co. Linden Government Research Lab Coast Guard Washington D.C. Department of Transportation Washington D.C. Office For Remote Sensing of Earth Resources. NASA Earth Resources Survey Program Pennsylvania State University Washington D.C. Department of the Navy Washington D.C. Cambridge. Dept. of Mechanical Engineering Massachusetts Inst. of Technology USA Huntsville. School of Graduate Studies and Research Alabama Univ. USA Dept. of Microbiology. Office of Naval Research Maryland Univ. Arlington Research and Development Co. Pittsburgh AeroChem Research Labs. Inc. Princeton Dept. of the Interior Office of Library Services. Bibliographic Series (Final) Washington D.C. Interplan Corp. Santa Barbara Urban Mass Transportation Adm. Washington D.C. Naval Underwater Systems Center Newport Calif. Mercury Project. National Science Found Stanford Univ Washington D.C. Div. of Advanced Environmental Research & Tech. USA Corvallis. NASA Earth Resources Survey Program Oregon State Univ. Washington D.C. Riverside. Inst. of Geophysics and Planetary Physics National Science Foundation California Univ. Washington D.C. Livermore Lawrence Livermore Lab. California Univ. USA Atlantic Oceanographic and Meteorological Labs. National Oceanic and Atmospheric Administration Miami National Technical Information Service Springfield Miami Univ. Coral Gables School of Law National Oceanic and Atmospheric Administration Rockville National Academy of Sciences Office of Sea Grant Washington D. C. School of Law National Oceanic and Atmospheric Administration Office of Sea Grant. Rockville Norman. Dept. of Civil Engineering and Environmental Science. Urban Mass Transportation Administration Oklahoma Univ. Washington D. C. Knoxville.Dept. of Civil Engineering. Federal Highway Administration Tennessee Univ. Washington D. C. Amherst.Water Resources Research Center. Office of Water Research and Technology Massachusetts Univ. Washington D. C. Calif. Dept. of Industria

来源：评论

学校读者我要写书评

暂无评论

RNA engineering for Public Health: Innovations in RNA-Based Diagnostics and Therapeutics

引用

chemical and Biomolecular engineering 1000年第1期12卷 263-286页

作者： Walter Thavarajah Laura M. Hertz David Z. Bushhouse Chloé M. Archuleta Julius B. Lucks 3Center for Water Research Northwestern University Evanston Illinois 60208 USA 2Center for Synthetic Biology Northwestern University Evanston Illinois 60208 USA 1Department of Chemical and Biological Engineering Northwestern University Evanston Illinois 60208 USA email: jblucks@northwestern.edu 4Interdisciplinary Biological Sciences Graduate Program Northwestern University Evanston Illinois 60208 USA 5Center for Engineering Sustainability and Resilience Northwestern University Evanston Illinois 60208 USA

RNA is essential for cellular function: From sensing intra- and extracellular signals to controlling gene expression, RNA mediates a diverse and expansive list of molecular processes. A long-standing goal of synthetic biology has been to develop RNA engineering principles that can be used to harness and reprogram these RNA-mediated processes to engineer biological systems to solve pressing global challenges. Recent advances in the field of RNA engineering are bringing this to fruition, enabling the creation of RNA-based tools to combat some of the most urgent public health crises. Specifically, new diagnostics using engineered RNAs are able to detect both pathogens and chemicals while generating an easily detectable fluorescent signal as an indicator. New classes of vaccines and therapeutics are also using engineered RNAs to target a wide range of genetic and pathogenic diseases. Here, we discuss the recent breakthroughs in RNA engineering enabling these innovations and examine how advances in RNA design promise to accelerate the impact of engineered RNA systems.

关键词： RNA public health synthetic biology diagnostic therapeutic CRISPR

来源：评论

学校读者我要写书评

暂无评论

CORROSION RESISTANCE OF ALUMINUM ALLOY 5083 IN MARINE ENVIRONMENTS

引用

Journal of the American Society for Naval Engineers 1961年第3期73卷 545-547页

作者： AILOR, W.H. LINDBERG, R.I. William H. Ailor has been a member of the Chemical Metallurgy Section of the Metallurgical Research Division Reynolds Metals Company for six years. Educated in chemistry and chemical engineering at the University of Tampa Florida and North Carolina State College. He is Task Force chairman of the ASTM B-3/V1 1957 20-Year Test Program for the atmospheric corrosion of metals secretary of ASTM Committee B-3 and is a member of the Electrochemical Society and the National Association of Corrosion Engineers. He formerly taught diesel engineering at North Carolina State College. He is a lieutenant commander in the Naval Reserve. During World War II he served as engineering officer afloat and later as commanding officer of USS PC 616 and USS Belet (APD-109). Recalled to service in the Korean conflict he served 17 months as executive officer of the USS Robinson (DD 562). He is in the active reserve and formerly was commanding officer of Surface Division 6–42 in Jacksonville Fla. Currently he is training officer of MSTS Co. 5-1 in Richmond Va. R. I. Lindberg is a corrosion engineer in the engineering services department of Reynolds Metals Company. Author of several papers on corrosion in marine environments Mr. Lindberg is a member of the National Association of Corrosion Engineers. Prior to joining Reynolds in 1959 Mr. Lindberg was director of corrosion research for A. M. Byers Co. Pittsbugh Pa. Mr. Lindberg graduated from the University of Cincinnati in 1939 with B. S. and Ch. E. degrees. He took post graduate work at Purdue University receiving a Master of Science degree in 1942.

来源：评论

学校读者我要写书评

暂无评论

Nature Versus Nurture: Developing Enzymes That Function Under Extreme Conditions

引用

chemical and Biomolecular engineering 1000年第1期3卷 77-102页

作者： Michael J. Liszka Melinda E. Clark Elizabeth Schneider Douglas S. Clark 1Department of Chemical and Biomolecular Engineering 2Energy Biosciences Institute 3UC Berkeley and UCSF Graduate Program in Bioengineering University of California Berkeley California 94720 email: mliszka@berkeley.edu melinda_clark@berkeley.edu ebeth@berkeley.edu clark@berkeley.edu

Many industrial processes used to produce chemicals and pharmaceuticals would benefit from enzymes that function under extreme conditions. Enzymes from extremophilic microorganisms have evolved to function in a variety of extreme environments, and bioprospecting for these microorganisms has led to the discovery of new enzymes with high tolerance to nonnatural conditions. However, bioprospecting is inherently limited by the diversity of enzymes evolved by nature. Protein engineering has also been successful in generating extremophilic enzymes by both rational mutagenesis and directed evolution, but screening for activity under extreme conditions can be difficult. This review examines the emerging synergy between bioprospecting and protein engineering in developing extremophilic enzymes. Specific topics include unnatural industrial conditions relevant to biocatalysis, biophysical properties of extremophilic enzymes, and industrially relevant extremophilic enzymes found either in nature or through protein engineering.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Microfluidic Strategies for Understanding the Mechanics of Cells and Cell-Mimetic Systems

引用

chemical and Biomolecular engineering 1000年第1期6卷 293-317页

作者： Joanna B. Dahl Jung-Ming G. Lin Susan J. Muller Sanjay Kumar 1Department of Chemical and Biomolecular Engineering 3UC Berkeley/UCSF Graduate Program in Bioengineering University of California Berkeley California 94720 email: skumar@berkeley.edu 2Department of Bioengineering

Microfluidic systems are attracting increasing interest for the high-throughput measurement of cellular biophysical properties and for the creation of engineered cellular microenvironments. Here we review recent applications of microfluidic technologies to the mechanics of living cells and synthetic cell-mimetic systems. We begin by discussing the use of microfluidic devices to dissect the mechanics of cellular mimics, such as capsules and vesicles. We then explore applications to circulating cells, including erythrocytes and other normal blood cells, and rare populations with potential disease diagnostic value, such as circulating tumor cells. We conclude by discussing how microfluidic devices have been used to investigate the mechanics, chemotaxis, and invasive migration of adherent cells. In these ways, microfluidic technologies represent an increasingly important toolbox for investigating cellular mechanics and motility at high throughput and in a format that lends itself to clinical translation.

关键词： particles droplets capsules vesicles migration chemotaxis

来源：评论

学校读者我要写书评

暂无评论

At Light Speed: Advances in Optogenetic Systems for Regulating Cell Signaling and Behavior

引用

chemical and Biomolecular engineering 1000年第1期8卷 13-39页

作者： Nicole A. Repina Alyssa Rosenbloom Abhirup Mukherjee David V. Schaffer Ravi S. Kane 2Graduate Program in Bioengineering University of California San Francisco and University of California Berkeley California 94720 email: nrepina@berkeley.edu 1Department of Bioengineering University of California Berkeley California 94720 email: alyssa.rosenbloom@berkeley.edu 3School of Chemical and Biomolecular Engineering Georgia Institute of Technology Atlanta Georgia 30332 email: abhimukh2015@gatech.edu ravi.kane@chbe.gatech.edu 4Department of Chemical and Biomolecular Engineering University of California Berkeley California 94720 email: schaffer@berkeley.edu 6Department of Molecular and Cell Biology University of California Berkeley California 94720 5Helen Wills Neuroscience Institute University of California Berkeley California 94720

Cells are bombarded by extrinsic signals that dynamically change in time and space. Such dynamic variations can exert profound effects on behaviors, including cellular signaling, organismal development, stem cell differentiation, normal tissue function, and disease processes such as cancer. Although classical genetic tools are well suited to introduce binary perturbations, new approaches have been necessary to investigate how dynamic signal variation may regulate cell behavior. This fundamental question is increasingly being addressed with optogenetics, a field focused on engineering and harnessing light-sensitive proteins to interface with cellular signaling pathways. Channelrhodopsins initially defined optogenetics; however, through recent use of light-responsive proteins with myriad spectral and functional properties, practical applications of optogenetics currently encompass cell signaling, subcellular localization, and gene regulation. Now, important questions regarding signal integration within branch points of signaling networks, asymmetric cell responses to spatially restricted signals, and effects of signal dosage versus duration can be addressed. This review summarizes emerging technologies and applications within the expanding field of optogenetics.

关键词：

来源：评论

学校读者我要写书评

暂无评论

THREE YEAR TIDEWATER CORROSION OF ALUMINUM ALLOYS

引用

Naval Engineers Journal 1964年第3期76卷 443-450页

作者： AILOR, WILLIAM H. REINHART, FRED M. William H. Ailor has been a member of the Chemical Metallurgy Section of the Metallurgical Research Division Reynolds Metals Company for nine years. He holds degrees in chemistry and chemical engineering from the University of Tampa Florida and North Carolina State. He is Task Force Chairman of an ASTM 20-Year Test Program for the atmospheric corrosion of metals secretary of ASTM Committee B-3 and is a member of the Electrochemical Society the National Association of Corrosion Engineers and the American Society of Naval Engineers. He formerly taught diesel engineering at North Carolina State. He is a Lieutenant Commander in the Naval Reserve. During World War II he served as engineering officer afloat and later as commanding officer of USS PC 616 and USS Belet (APD-109). Recalled to service in the Korean conflict he served 17 months as executive officer of the USS Robinson (DD 562). He is in the active reserve and formerly was commanding officer of Naval Reserve Surface Division 6–42 in Jacksonville Florida. Currently he is training officer of MSTS Co. 5-1 in Richmond Va. Fred M. Reinhart has been a Senior Project Scientist (Metallurgist) Materials Division Civil Engineering Department U. S. Naval Civil Engineering Laboratory Port Hueneme California since September 1962. From 1937 to 1962 he was chemist metallurgist supervisory physical metallurgist and supervisory aeronautical materials research engineer Metallurgy Division National Bureau of Standards. Mr. Reinhart has written many papers that have been published in the technical literature and is the author of one technical publication ASTM STP290 “Twenty-Year Atmospheric Corrosion Investigation of Zinc-Coated and Uncoated Wire and Wire Products. He is a member of ASM and was Chairman of the Washington Chapter 1951-52 a member of ASTM with membership on Committees A-5 A-10 and B-3 and was Chairman of Subcommittee XV of A-5 from 1952 to 1962 a member of NACE and was Chairman of the Editorial Review Subcommittee of the Publications Committee f

来源：评论

学校读者我要写书评

暂无评论

Engineered Ribosomes for Basic Science and Synthetic Biology

引用

chemical and Biomolecular engineering 1000年第1期9卷 311-340页

作者： Anne E. d'Aquino Do Soon Kim Michael C. Jewett 3Department of Chemical and Biological Engineering Northwestern University Evanston Illinois 60208 USA 2Center for Synthetic Biology Northwestern University Evanston Illinois 60208 USA 1Interdisciplinary Biological Sciences Graduate Program Northwestern University Evanston Illinois 60208 USA email: m-jewett@northwestern.edu

The ribosome is the cell's factory for protein synthesis. With protein synthesis rates of up to 20 amino acids per second and at an accuracy of 99.99%, the extraordinary catalytic capacity of the bacterial translation machinery has attracted extensive efforts to engineer, reconstruct, and repurpose it for biochemical studies and novel functions. Despite these efforts, the potential for harnessing the translation apparatus to manufacture bio-based products beyond natural limits remains underexploited, and fundamental constraints on the chemistry that the ribosome's RNA-based active site can carry out are unknown. This review aims to cover the past and present advances in ribosome design and engineering to understand the fundamental biology of the ribosome to facilitate the construction of synthetic manufacturing machines. The prospects for the development of engineered, or designer, ribosomes for novel polymer synthesis are reviewed, future challenges are considered, and promising advances in a variety of applications are discussed.

关键词： ribosome cell-free tethered ribosome engineering peptides translation

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：