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2nd TALENTA-International Conference on science and Technology, TALENTA-ICST 2020

作者： Irham, M.A. Muttaqien, F. Bisri, S.Z. Iskandar, F. Electronics Material Physics Research Group Faculty of Mathematics and Natural Sciences Institut Teknologi Bandung Jl. Ganesha 10 Bandung40132 Indonesia Instrumentation and Computational Physics Research Group Faculty of Mathematics and Natural Sciences Institut Teknologi Bandung Jl. Ganesha 10 Bandung40132 Indonesia Master Program in Computational Science Faculty of Mathematics and Natural Sciences Institut Teknologi Bandung Jl. Ganesha 10 Bandung40132 Indonesia RIKEN Center for Emergent Matter Science 2-1 Hirosawa Saitama Wako351-0198 Japan Research Center for Nanosciences and Nanotechnology Institut Teknologi Bandung Jl. Ganesha 10 Bandung 40132 Indonesia

Supercapacitor gains so much interest in recent years due to its capabilities to provide high power densities with high energy density possibilities. Several transition metal sulfides (TMS) give the best capacitance results nowadays, with Copper Sulfides (CuS) promising candidates on supercapacitor electrodes materials. Several approaches have been made to increase TMS-based supercapacitor performance, such as doping, surface functionalization, and nanostructuring. Even though several dopants already reported, other dopants have not yet explored. In this study, we study the nickel effect as dopant on the binding energy of electrolyte in the surface of CuS from first-principles viewpoints. In this study, we limit our investigation of surface interaction with electrolyte only for OH- ions. We prove that the binding energy of electrolyte is increased after introducing dopant in the surface of CuS, which could explain of dopant effect and background proof of future research in this field. © 2023 Institute of Physics Publishing. All rights reserved.

关键词： Copper compounds

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Effect of Ag38kDa recombinant protein antibodies of Mycobacterium tuberculosis and Rifampicin on CD4 and CD8 lymphocytes: Ex vivo study

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AIP Conference Proceedings 2023年第1期2634卷

作者： Dwi Yuni Nurhidayati Yuliati Yuliati Almira Fahrinda Tri Yudhani Mardining Raras Hidayat Sujuti Sumarno Reto Prawiro 1Department of Clinical Microbiology Faculty of Medicine University of Brawijaya 65145 Malang Indonesia 2Master Program in Biomedical Science Faculty of Medicine University of Brawijaya 65145 Malang Indonesia 3Department of Biochemistry and Molecular Biology Faculty of Medicine University of Brawijaya Malang 65145 Indonesia

Tuberculosis is a global epidemic, one of the top 10 causes of death in the world. One of the potent anti-tuberculosis drugs used in the treatment of tuberculosis is Rifampicin. Meanwhile, Ag38kDa recombinant protein contains 2 Mtb-specific B cell epitopes and is believed to be the most potent immunogen. The purpose of this study is to compare Rifampicin with recombinant protein antibody Ag38kDa and the combination of both in stimulating the response of T-lymphocytes by observing the percentage of CD4+ and CD8+ cells that can be a breakthrough for the treatment of active tuberculosis. This study involved several treatment groups, the antibody recombinant protein Ag38kDa group, the Rifampicin group, and the combination group. All treatment groups were compared with positive controls. All treatment groups were examined by flow cytometry, and SPSS statistics were adopted to calculate the results. The average percentage of CD4+ cells treated with Rifampicin increases compared to the control (0.00<0.05). For CD8+, there is a significant increase in all treatment groups compared to controls (0.00<0.05). The increase of CD4+ and CD8+ aid the bacteria eradication process that infects cells and inhibits the growth and spread of mycobacteria in tuberculosis.

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Image security development using 3D playfair cipher combination and bit shift

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AIP Conference Proceedings 2022年第1期2391卷

作者： Kiswara Agung Santoso Rika Ayu Sukmawati Agustina Pradjaningsih 1University of Jember Jl. Kalimantan No. 37 KampusTegal Boto Jember Indonesia 2Master Program of Mathematics Department Faculty of Science University of Jember Jl. Kalimantan No. 37 KampusTegal BotoJember Indonesia

Messaging in this modern era is growing really fast because it’s so easy to use. The more development of messaging, the easier it is for third parties to access the contents of the message. Cryptography is needed to learn about how a message remains safe. This research is to develop the security of a message in encoding an image using a combination of 30 Playfair Cipher and Bit Shift. The encryption and decryption process of 30 Playfair Cipher using a pair of three letters (trigram) is followed by shifting the bits up, right, down, and left in the image which is done several iterations repeatedly. The encryption process produces a different cipherimage with a visually plainimage. The decryption process successfully returns the cipherimage to plainimage. Combination of 30 Playfair Cipher and Bit Shift using histogram analysis, NPCR, UACI, and correlation coefficient to see the difference in calculation value between plainimage and cipherimage, and the result of the average values are 455743,6698; 99,51275%; 31,92532%; and 0,054784798. The results showed that the combination of 30 Playfair Cipher and Bit Shift can be used to secure a message.

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Water quality management for in-vitro test of recombinant vaccines on cantang grouper (Epinephelus sp.)

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AIP Conference Proceedings 2022年第1期2513卷

作者： Uun Yanuhar Diana Arfiati Muhammad Musa Choirul Huda Nur Sakinah Junirahma Nico Rahman Caesar 1Aquatic Resources Management Faculty of Fisheries and Marine Sciences University of Brawijaya Malang Jl. Veteran Malang – East Java Indonesia 65145 2Master Program of Aquaculture Faculty of Fisheries and Marine Science University of Brawijaya Jl. Veteran Malang 65145 Indonesia 3Doctoral program of Environmental Science Postgraduate Program University of Brawijaya Jl. Veteran Malang 65145 Indonesia

There is a close relationship between water quality conditions in the maintenance system and the health of cantang grouper (Epinephelus sp.). The main triggers of water quality are the following suboptimal levels were temperature, salinity, pH, and dissolved oxygen. Therefore, it is necessary to carry out water quality management in grouper rearing pond that is vaccinated to create controlled environmental conditions. The method used in this research is experimental. Water quality monitoring was carried out in all treatment tanks used for recombinant vaccines test, there were (A) Normal fish without treatment; (B) VNN-Infected fish; (C) Healthy fish with 33 µl vaccine treatment; (D) Healthy fish with 66 µl vaccine treatment; (E) Healthy fish with 112 µl vaccine treatment; (F) VNN-Infected fish with 33 µl vaccine treatment; (G) VNN-Infected fish with 66 µl vaccine treatment; and (H) VNN-Infected fish with 112 µl vaccine treatment; (I) Healthy fish with 33 µl vaccine treatment then infected with VNN; (J) Healthy fish treated with 66 µl vaccine then infected with VNN; (K) Healthy fish with 112 µl vaccine treatment then infected with VNN. Water quality control was carried out during the recombinant vaccine treatment process by adding an aerator for oxygen supply and heater to keep the temperature stable. The results of water quality temperature parameters were obtained in the range of 30-31°C, the salinity of 30 ppt, pH 7.5-7.8 and dissolved oxygen between 17.2-19.1 mg L-1. The water quality condition in grouper tanks with vaccine treatments was good and following the water quality standards that supports the life of cantang grouper. Water temperature has a major influence on the initiation and transmission of several fish diseases. The water quality in this study showed optimal values, thus supporting controlled water quality conditions during the recombinant vaccine treatment.

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Theoretical study on adsorption and reaction of polymeric formic acid on the Cu(111) surface

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Physical Review Materials 2021年第7期5卷 075801-075801页

作者： Septia Eka Marsha Putra Fahdzi Muttaqien Yuji Hamamoto Kouji Inagaki Akitoshi Shiotari Jun Yoshinobu Yoshitada Morikawa Ikutaro Hamada Department of Precision Engineering Graduate School of Engineering Osaka University 2-1 Yamada-oka Suita Osaka 565-0871 Japan Department of Engineering Physics Institut Teknologi Sumatera Jalan Terusan Ryacudu Way Hui Jati Agung South Lampung 35365 Indonesia Instrumentation and Computational Physics Research Group Faculty of Mathematics and Natural Sciences Institut Teknologi Bandung Jalan Ganesha 10 Bandung West Java 40132 Indonesia Master Program in Computational Science Faculty of Mathematics and Natural Sciences Institut Teknologi Bandung Jalan Ganesha 10 Bandung West Java 40132 Indonesia Elements Strategy Initiative for Catalysts and Batteries (ESICB) Kyoto University Goryo-Ohara Nishikyou-ku Katsura Kyoto 615-8245 Japan Department of Advanced Materials Science The University of Tokyo 5-1-5 Kashiwanoha Kashiwa Chiba 277-8561 Japan The Institute for Solid State Physics The University of Tokyo 5-1-5 Kashiwanoha Kashiwa Chiba 277-8581 Japan Research Center for Precision Engineering Graduate School of Engineering Osaka University 2-1 Yamada-oka Suita Osaka 565-0871 Japan

We investigate the polymeric adsorption of formic acid (HCOOH) on the Cu(111) surface by means of density functional theory. We present structural models for the polymeric form of HCOOH on Cu(111) and characterize their stability, electronic, and vibrational properties. Based on the energetics and dynamics, as well as simulated scanning tunneling microscopy and atomic force microscopy images, we propose that the α polymorph is likely to be formed on the Cu(111) surface and can explain the experimental findings. We also study the initial step of the catalytic dehydrogenation of HCOOH and find that the O-H bond dissociation at the edge of the polymer is facilitated, rather than that forming hydrogen bonding, agreeing well with the experiments.

关键词： Adsorption Chemical bonding Chemical kinetics, dynamics & catalysis Electronic structure Surface & interfacial phenomena Surfaces Density functional theory First-principles calculations

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The structure of barium M-hexaferrite (BaFe12-2xCoxNixO19) powders using co-precipitation methods

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AIP Conference Proceedings 2020年第1期2251卷

作者： Susilawati Aris Doyan Muhammad Taufik Wahyudi 1Physics Education FKIP University of Mataram Lombok West Nusa Tenggara Indonesia 2Master of Science Education Study Program University of Mataram West Nusa Tenggara Indonesia

Barium M-hexaferrite were synthesized with Co-Ni doping ions (BaFe12-2xCoNixO19) using the co-precipitation method, based on the natural iron sand of the Loang Balok beach, Sekarbela District, Mataram, Indonesia. The synthesis was carried out with variations in the concentration of doping ions (x = 0.0, 0.6, and 1.0). The characterization of the sample was completed using XRD, SEM-EDX, TEM. The XRD results showed that the sample had a hexagonal structure because it had a c / value of 2.3 to 2.6. In contrast, SEM-EDX showed that the sample size of BaFe12CoNiO19 had reached the range of nanoparticles from 41 nm to 151 nm which was evenly distributed, with a composition of Ba = 12.22%; Fe = 49.1%; Co = 8.78%; Ni = 4.76%; and O = 21.37%, and slight impurities Cl = 3.77%.

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SARS-CoV-2 infections in certain groups: A review from COVID-19 study cases

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AIP Conference Proceedings 2023年第1期2606卷

作者： Muhammad Mumtaz Adzdzakiy Isnaini Zakiyyah Asyifa Alvira Rifdah Sativa Ahmad Ridha Al Fiqri Anik Budhi Dharmayanthi Anggia Prasetyoputri Sugiyono Saputra 1Graduate Program of Bioscience Faculty of Mathematics and Natural Sciences Universitas Sebelas Maret Jl. Ir. Sutami 36A Surakarta Central Java Indonesia 57126 2Master Program in Biomedical Science Faculty of Medicine Universitas Indonesia Jl. Salemba Raya No. 6 Jakarta Indonesia 10430 3School of Life Science and Technology Bandung Institute of Technology Jl. Ganesa 10 Bandung West Java Indonesia 40132 4Research Center for Biology National Research and Innovation Agency (BRIN) Jl. Raya Jakarta Bogor Km 46 Bogor West Java Indonesia 16911 5Research Center for Biotechnology National Research and Innovation Agency (BRIN) Jl. Raya Jakarta Bogor Km 46 Bogor West Java Indonesia 16911

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused the current pandemic of COVID-19 and is highly infectious with relatively high mortality risk. In this study, we reviewed and summarized miscellaneous COVID-19 cases from vulnerable groups, including children and those with comorbidity, reinfections, coinfections and vaccinated individuals, and rapid transmission cases to understand if there are any specific SARS-CoV-2 variants that infect those groups. We concluded that there were no specific variants associated with higher rates of infection within certain groups, rather, they may tend to infect any groups with any immunity levels, regardless of geographical boundaries. A high prevalence of SARS-CoV-2 infection is mainly driven by the ability of viruses with genetic markers that have been associated with higher risks of transmission and immune escape in vulnerable groups. Disease severity is not only influenced by the virus, but also host conditions such as gender, age, comorbidity, and obesity. The likelihood of new emerging SARS-CoV-2 variants resulting from infections in vulnerable groups is high, thus monitoring viral genetic markers and mutations is crucial for outbreak preparedness.

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computational investigation of interaction between β-cyclodextrin and hydroxychloroquine

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AIP Conference Proceedings 2021年第1期2349卷

作者： Atthar L. Ivansyah 1Master Program in Computational Science Faculty of Mathematics and Natural Sciences Institut Teknologi Bandung Jalan Ganesha No. 10 Bandung West Java 40132 Indonesia 2Analytical Chemistry Research Group Department of Chemistry Faculty of Mathematics and Natural Sciences Institut Teknologi Bandung Jalan Ganesha No. 10 Bandung West Java 40132 Indonesia

There was an outbreak with symptoms similar to SARS caused by the SARS-CoV-2 virus in the People’s Republic of China at the end of 2019. The rapid spread of the virus, even in Indonesia, led to a pandemic status being given by the WHO. The use of current medications before a vaccine is identified and ready for help is one alternative to reducing COVID-19 patients. As a candidate for anti-COVID-19 drugs, Hydroxychloroquine has been extensively studied and has now reached the clinical trial stage. Hydroxychloroquine’s solubility in water, however, is so limited that it affects its low human body bioavailability. The development of a stable inclusion complex with β-cyclodextrin is one way to increase Hydroxychloroquine’s solubility in water. This research investigated the interaction between β-cyclodextrin and Hydroxychloroquine through molecular docking analysis and a semiempirical quantum process. The results of the semiempirical quantum method and the study of molecular docking suggest that β-cyclodextrin and Hydroxychloroquine are a stable inclusion complex. Hydroxychloroquine’s solubility in aqueous solution can also be increased by forming an inclusion complex with β-cyclodextrin.

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Theoretical investigation of interaction between hydroxypropyl-β-cyclodextrin and hydroxychloroquine

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AIP Conference Proceedings 2021年第1期2349卷

At the end of 2019, there was an outbreak with symptoms similar to SARS in the People’s Republic of China caused by the SARS-CoV-2 virus. The massive spread of the virus, including in Indonesia, caused the WHO to issue a pandemic status. One alternative to reducing COVID-19 patients is to use existing drugs until a vaccine is found and ready for use. Currently, hydroxychloroquine has been widely researched as a candidate for anti-COVID-19 medicines, which has now entered the clinical trial stage. However, the solubility of hydroxychloroquine in water is so small that it impacts its low bioavailability in the human body. One way to increase hydroxychloroquine’s solubility in water is through the formation of a stable inclusion complex with hydroxypropyl-β-cyclodextrin. In this research, a molecular docking study and semiempirical quantum method were conducted to investigate the interaction between hydroxypropyl-β-cyclodextrin and hydroxychloroquine. The molecular docking study results and semiempirical quantum method show that hydroxypropyl-β-cyclodextrin and hydroxychloroquine form stable inclusion complex. The solubility of hydroxychloroquine in aqueous solution can be enhanced by forming an inclusion complex with hydroxypropyl-β-cyclodextrin.

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How do you teach? Teachers’ perceptions on teaching biology and pedagogical content knowledge skills

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AIP Conference Proceedings 2019年第1期2194卷

作者： Murni Ramli Puguh Karyanto Siti Wulandari 1Department of Biology Education Faculty of Teacher Training and Education 2Master Program of Science Education Universitas Sebelas Maret Surakarta Indonesia

This research tested 35 high school biology teachers in Surakarta, Indonesia aims to check their perceptions about teaching biology, and analyzed their PCK profiles. Respondents were public and private schools’ teachers who voluntary agreed to join the survey. A multiple-choice test developed based on the indicators of PCK was used to explore teacher’s perceptions. The results showed that 77.14% of teachers preferred to use a kinesthetic teaching strategy, focus on measuring the lower and higher thinking skills (51.43%), and 80% teachers eager to train conceptual understanding and its application instead of preparation for the high stakes examination.

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