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Adaptive and iterative gene selection based on least squares support vector regression

Journal of Information and computational Science 2006年第3期3卷 443-451页

作者： Jiang, Jingqing Wu, Chunguo Song, Chuyi Liang, Yanchun Key Laboratory of Symbol Computation and Knowledge Engineering College of Computer Science and Technology Jilin University Changchun 130012 China College of Mathematics and Computer Science Inner Mongolia University for Nationalities Tongliao 028043 China Key Laboratory of Information Science and Engineering of Railway Ministry The Key Laboratory of Advanced Information Science and Network Technology of Beijing Beijing Jiaotong University Beijing 100044 China

Cancer classification and identification are major areas in medical research. DNA microarrays could provide useful information for cancer classification at the gene expression level. The number of genes in a microarray is always several thousands while the number of training samples always several dozens. In such case most of the machine learning models suffer from the overfitting and it is necessary to select a handful of most informative genes. An adaptive and iterative gene selection algorithm based on least squares support vector machines is proposed in this paper. The algorithm adopts sequential forward selection search scheme. The number of selected genes can be determined adaptively. The total number of genes processed by the proposed algorithm is smaller than that processed by other algorithms using support vector machines. Results of numerical experiments show that the proposed algorithm trains fast and achieves comparable performance on two well-known benchmark problems.

关键词： Genes

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IInfoGAN: Improved Information Maximizing Generative Adversarial Networks

IInfoGAN: Improved Information Maximizing Generative Adversa...

引用

International Conference on Mechanical, Control and Computer engineering (ICMCCE)

作者： Yan Wang Pujia Wang Boyang Sun Kai He Lan Huang School of Artificial Intelligence Jilin University Changchun China Key Laboratory of Symbol Computation and Knowledge Engineering College of Computer Science and Technology Jilin University Ministry of Education Changchun China

Generative Adversarial Networks (GANs) have achieved huge success in some unsupervised learning fields. There is no doubt that clustering takes a lot of weight in unsupervised algorithm. And in this paper, we raise the Improved Information Maximizing Generative Adversarial Networks (IInfoGAN) algorithm for learning discriminative classifiers from unlabeled data. The basis of our method is an math function that contains the Mutual Information (MI) and Cross Entropy of the observed examples and their predicted classification category distribution, thus enhancing the robustness of the classifier to adversarial generative models. Experiments show that the interpretable representation learned by IInfoGAN is competitive with the representation learned by existing unsupervised methods.

关键词： Training Time series analysis Clustering algorithms Predictive models Generative adversarial networks Prediction algorithms Entropy

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Hyperbolic node embedding for signed networks

arXiv

引用

arXiv 2019年

作者： Song, Wenzhuo Chen, Hongxu Liu, Xueyan Jiang, Hongzhe Wang, Shengsheng College of Computer Science and Technology Jilin University Changchun130012 China Key Laboratory of Symbolic Computation Knowledge Engineering of Ministry of Education Jilin University Changchun130012 China Advanced Analytics Institute School of Computer Science Faculty of Engineering and IT University of Technology Sydney NSW2007 Australia College of Mechanical and Electronic Engineering Nanjing Forestry University Nanjing210037 China

Signed network embedding methods aim to learn vector representations of nodes in signed networks. However, existing algorithms only managed to embed networks into low-dimensional Euclidean spaces whereas many intrinsic features of signed networks are reported more suitable for non-Euclidean spaces. For instance, previous works did not consider the hierarchical structures of networks, which is widely witnessed in real-world networks. In this work, we answer an open question that whether the hyperbolic space is a better choice to accommodate signed networks and learn embeddings that can preserve the corresponding special characteristics. We also propose a non-Euclidean signed network embedding method based on structural balance theory and Riemannian optimization, which embeds signed networks into a Poincar ball in a hyperbolic space. This space enables our approach to capture underlying hierarchy of nodes in signed networks because it can be seen as a continuous tree. We empirically compare our method against six Euclidean-based baselines in three tasks on seven real-world datasets, and the results show the effectiveness of our method. Copyright © 2019, The Authors. All rights reserved.

关键词： Geometry

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Approximated non-tensor pre-wavelets neural network based on compound training algorithm

引用

Journal of Information and computational Science 2005年第4期2卷 715-722页

作者： Li, Ying Deng, Zhidong Zou, Xi Key Laboratory of Intelligent Technology and Systems Department of Computer Science and Technology Tsinghua University Beijing 100084 China Key Laboratory of Symbol Computation and Knowledge Engineering College of Computer Science and Technology Jilin University Changchun 130021 China Institute of Mathematics Jilin University Changchun 130021 China

In this paper, we propose a new supervised compound learning algorithm for training our constructed approximated bivariate non-tensor product adaptive pre-wavelet neural network (APWNN). On the one hand, the linear weights of APWNN are trained by the self-adaptive learning rate method. On the other hand an extended Kalman filter method is used to update the nonlinear parameters such as dilation parameters and translation parameters. Additionally we demonstrate the efficiency of our proposed method through a concrete example of function approximation.

关键词： Neural networks

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Using spatial clustering in precision agriculture

引用

Harbin Gongye Daxue Xuebao/Journal of Harbin Institute of Technology 2005年第SUPPL. 4期37卷 31-34页

作者： Wang, Sheng-Sheng Liu, Da-You Liu, Jie Wang, Xin-Ying Key Laboratory of Symbolic Computing and Knowledge Engineering College of Computer Science and Technology Jilin University Changchun 130012 China

There are lots of data with multidimensional attributes and spatial position information in precision agriculture applications. Based on the high dimensional spatial clustering algorithm, the agriculture breed partition method is proposed and applied in Chinese national 863 project. The data mining algorithm is performed in this way: cluster the multidimensional attributes first, then cluster the spatial position information using the former attributes clustering results. Experiments show that the two-phases clustering method is prior to the traditional single-phase clustering method. According to the clustering results, one will decide the region belongs to what kind of soil, select the breeds and the field managements.

关键词： Data mining

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Distantly Supervised Relation Extraction via Recursive Hierarchy-Interactive Attention and Entity-Order Perception

arXiv

引用

arXiv 2021年

作者： Han, Ridong Peng, Tao Han, Jiayu Cui, Hai Liu, Lu College of Computer Science and Technology Jilin University Jilin Changchun130012 China College of Software Jilin University Jilin Changchun130012 China Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Jilin University Jilin Changchun130012 China Department of Linguistics University of Washington SeattleWA98195 United States

Wrong-labeling problem and long-tail relations severely affect the performance of distantly supervised relation extraction task. Many studies mitigate the effect of wrong-labeling through selective attention mechanism and handle long-tail relations by introducing relation hierarchies to share knowledge. However, almost all existing studies ignore the fact that, in a sentence, the appearance order of two entities contributes to the understanding of its semantics. Furthermore, they only utilize each relation level of relation hierarchies separately, but do not exploit the heuristic effect between relation levels, i.e., higher-level relations can give useful information to the lower ones. Based on the above, in this paper, we design a novel Recursive Hierarchy-Interactive Attention network (RHIA) to further handle long-tail relations, which models the heuristic effect between relation levels. From the top down, it passes relation-related information layer by layer, which is the most significant difference from existing models, and generates relation-augmented sentence representations for each relation level in a recursive structure. Besides, we introduce a newfangled training objective, called Entity-Order Perception (EOP), to make the sentence encoder retain more entity appearance information. Substantial experiments on the popular New York Times (NYT) dataset are conducted. Compared to prior baselines, our RHIA-EOP achieves state-of-the-art performance in terms of precision-recall (P-R) curves, AUC, Top-N precision and other evaluation metrics. Insightful analysis also demonstrates the necessity and effectiveness of each component of RHIA-EOP. © 2021, CC BY.

关键词： Semantics

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Document-level Relation Extraction with Relation Correlations

arXiv

引用

arXiv 2022年

作者： Han, Ridong Peng, Tao Wang, Benyou Liu, Lu Wan, Xiang College of Computer Science and Technology Jilin University China Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education China College of Software Jilin University China Shenzhen Research Institute of Big Data The Chinese University of Hong Kong Shenzhen China School of Data Science The Chinese University of Hong Kong Shenzhen China

Document-level relation extraction faces two overlooked challenges: long-tail problem and multi-label problem. Previous work focuses mainly on obtaining better contextual representations for entity pairs, hardly address the above challenges. In this paper, we analyze the co-occurrence correlation of relations, and introduce it into DocRE task for the first time. We argue that the correlations can not only transfer knowledge between data-rich relations and data-scarce ones to assist in the training of tailed relations, but also reflect semantic distance guiding the classifier to identify semantically close relations for multi-label entity pairs. Specifically, we use relation embedding as a medium, and propose two co-occurrence prediction sub-tasks from both coarse- and fine-grained perspectives to capture relation correlations. Finally, the learned correlation-aware embeddings are used to guide the extraction of relational facts. Substantial experiments on two popular DocRE datasets are conducted, and our method achieves superior results compared to baselines. Insightful analysis also demonstrates the potential of relation correlations to address the above challenges. Copyright © 2022, The Authors. All rights reserved.

关键词： Extraction

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Method for Preoperative Prediction of Microvascular Invasion of Hepatocellular Carcinoma

Method for Preoperative Prediction of Microvascular Invasion...

引用

IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

作者： Chen Zhao Tian Bai Tongjia Chu Feng Wei Fa Zhang College of Computer Science and Technology Jilin University Changchun China Key Laboratory of Symbolic Computation and Knowledge Engineering Ministry of Education Jilin University Changchun China Hepatobiliary and Pancreas Department General Surgery Center First Hospital of Jilin University Changchun China School of Medical Technology Beijing Institute of Technology Beijing China

ISBN: (数字)9781665468190

ISBN: (纸本)9781665468206

Microvascular invasion (MVI) in hepatocellular carcinoma (HCC) is of great guiding significance for the formulating treatment strategies and accessing the prognosis before the surgery. However, in traditional medicine, the gold standard for the diagnosis of MVI is obtained by examining pathological images which can only be obtained by sampling and sectioning tumors after surgery. At this time, MVI results have lost the timeliness of guiding tumor resection surgery. In order to solve this problem, existing studies began to use deep learning-based methods for preoperative prediction of MVI using non-invasive imaging. Most of these methods adopt the fusion methods of multi-sequence images to predict MVI, but fail to make full use of the characteristics of multiply sequences as prior knowledge to combine into the model, resulting in no further improvement of prediction performance. So we propose a multi-sequence image difference and correlation deep learning model. The model can extract the difference and correlation information between sequences from different scales and combine them into the model. To validate proposed model, we collected a data set consists of 120 HCC patients, including 50 MVI-positive patients. Compared with existing studies, our method has greatly improved in all evaluation metrics.

关键词： Deep learning Pathology Correlation Biological system modeling Surgery Predictive models Data mining

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Multimodal Medical Image Feature Representation and Fusion for AD Early Diagnosis

Multimodal Medical Image Feature Representation and Fusion f...

引用

IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

作者： Jing Qu Ying Qu Xueliang Bai Lanxin Xu Han Wang Guixia Liu College of Computer Science and Technology Jilin University Changchun China Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Jilin University Changchun China College of Science North China University of Science and Technology Tangshan China School of Information Science and Technology Institute of Computational Biology Northeast Normal University Changchun China

ISBN: (数字)9798350386226

ISBN: (纸本)9798350386233

Alzheimer's disease (AD) is progressive and gets worse with time. Early detection is an effective treatment for the disease, which can timely implement effective interventions. The multi-modal medical image contains more comprehensive and abundant information about the disease, which can reflect the different aspects of AD and reduce the potential bias in single-modal diagnosis. However, an effective and reliable solution is still lacking, which can integrate multimodal neuroimaging effectively for the precision diagnosis and treatment of AD. In this work, we proposed a feature representation and fusion model of MRI and PET scans based on a multiscale convolution network and cross-attention for AD early diagnosis, named camAD. Compared with the existing models, camAD performs better with fewer pre-processing steps. Using the Alzheimer’s disease neuroimaging initiative (ADNI) datasets, we demonstrated that integrating multi-modality data outperforms single-modality models in accuracy, specificity, sensitivity, AUC, and F1 scores. Our models exhibited significantly good accuracy and generality in four classification tasks, which provided a promising way to understand the underlying mechanisms of the disorder's progression.

关键词： Neuroimaging Accuracy Sensitivity Convolution Magnetic resonance imaging Feature extraction Data models Reliability Alzheimer's disease Medical diagnostic imaging

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An improved particle swarm optimization algorithm for flowshop scheduling problem

An improved particle swarm optimization algorithm for flowsh...

引用

International Conference on Information and Automation (ICIA)

作者： Bo Li Changsheng Zhang Ge Bai Erliang Zhang a. The computing center of Changchun Institute of Technology b. Key Laboratory of Symbol Computation and Knowledge Engineering of the Ministry of Education c. Aviation university of air force Changchun China

The flowshop scheduling problem has been widely studied in the literature and many techniques have been applied to it, but few algorithms have been proposed to solve it using particle swarm optimization algorithm (PSO) based algorithm. In this paper, an improved PSO algorithm (IPSO) based on the ldquoall differentrdquo constraint is proposed to solve the flowshop scheduling problem with the objective of minimizing makespan. It combines the particle swarm optimization algorithm with genetic operators together effectively. When a particle is going to stagnates, the mutation operator is used to search its neighborhood. The proposed algorithm is tested on different scale benchmarks and compared with the recently proposed efficient algorithms. The results show that both the solution quality and the convergent speed of the IPSO algorithm precede the other two recently proposed algorithms. It can be used to solve large scale flowshop scheduling problem effectively.

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