Integrating a prosthetic hand to amputees with seamless neural compatibility presents a grand challenge to neuroscientists and neural engineers for more than half *** anatomical structure or appearance of human hand d...
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Integrating a prosthetic hand to amputees with seamless neural compatibility presents a grand challenge to neuroscientists and neural engineers for more than half *** anatomical structure or appearance of human hand does not lead to improved neural connectivity to the sensorimotor system of *** functions of modern prosthetic hands do not match the dexterity of human hand due primarily to lack of sensory awareness and compliant ***,progress in restoring sensory feedback has marked a significant step forward in improving neural continuity of sensory information from prosthetic hands to ***,little effort has been made to replicate the compliant property of biological muscle when actuating prosthetic ***,a full-fledged biorealistic approach to designing prosthetic hands has not been contemplated in neuroprosthetic *** this perspective article,we advance a novel view that a prosthetic hand can be integrated harmoniously with amputees only if neural compatibility to the sensorimotor system is *** ongoing research supports that the next-generation prosthetic hand must incorporate biologically realistic actuation,sensing,and reflex functions in order to fully attain neural compatibility.
Sleep benefits the restoration of energy metabolism and thereby suppo rts neuronal plasticity and cognitive ***6 is a NAD+-dependent protein deacetylase that has been recognized as an essential regulator of energy met...
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Sleep benefits the restoration of energy metabolism and thereby suppo rts neuronal plasticity and cognitive ***6 is a NAD+-dependent protein deacetylase that has been recognized as an essential regulator of energy metabolism because it modulates various transcriptional regulators and metabolic *** aim of this study was to investigate the influence of Sirt6 on cerebral function after chronic sleep deprivation(CSD).We assigned C57BL/6J mice to control or two CSD groups and subjected them to AAV2/9-CMV-EGFP or AAV2/9-CMV-Sirt6-EGFP infection in the prelimbic cortex(PrL).We then assessed cerebral functional connectivity(FC) using resting-state functional MRI,neuron/astrocyte metabolism using a metabolic kinetics analysis;dendritic spine densities using sparse-labeling;and miniature excitato ry postsynaptic currents(mEPSCs) and action potential(AP) firing rates using whole-cell patchclamp *** addition,we evaluated cognition via a comprehensive set of behavioral *** with controls,Sirt6 was significantly decreased(P<0.05) in the PrL after CSD,accompanied by cognitive deficits and decreased FC between the PrL and accumbens nucleus,piriform cortex,motor co rtex,somatosensory co rtex,olfactory tubercle,insular cortex,and ***6 ove rexpression reve rsed CSD-induced cognitive impairment and reduced *** analysis of metabolic kinetics using [1-13C] glucose and [2-13C] acetate showed that CSD reduced neuronal Glu4and GABA2synthesis,which could be fully restored via forced Sirt6 ***,Sirt6 ove rexpression reversed CSD-induced decreases in AP firing rates as well as the frequency and amplitude of mEPSCs in PrL pyramidal *** data indicate that Sirt6 can improve cognitive impairment after CSD by regulating the PrL-associated FC network,neuronal glucose metabolism,and glutamatergic ***,Sirt6 activation may have potential as a novel strategy for treating sleep disorder-related diseases.
Modulating image restoration level aims to generate a restored image by altering a factor that represents the restoration strength. Previous works mainly focused on optimizing the mean squared reconstruction error, wh...
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Wind power curve describes the relationship between wind speed and output power of wind turbine, which may be contaminated due to various unexpected factors. Following the idea of image segmentation in our previous wo...
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According to SEM photos of ZrO2 coatings prepared by plasma spraying, 24 physical models with different porosities were constructed, and ultrasonic testing was simulated by finite-difference time-domain method, and th...
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In immersive humanoid robot teleoperation, there are three main shortcomings that can alter the transparency of the visual feedback: (i) the lag between the motion of the operator's and robot's head due to net...
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ISBN:
(数字)9798350309799
ISBN:
(纸本)9798350309805
In immersive humanoid robot teleoperation, there are three main shortcomings that can alter the transparency of the visual feedback: (i) the lag between the motion of the operator's and robot's head due to network communication delays or slow robot joint motion. This latency could cause a noticeable delay in the visual feedback, which jeopardizes the embodiment quality, can cause dizziness, and affects the interactivity resulting in operator frequent motion pauses for the visual feedback to settle; (ii) the mismatch between the camera's and the headset's field-of-views (FOV), the former having generally a lower FOV; and (iii) a mismatch between human's and robot's range of motions of the neck, the latter being also generally lower. In order to leverage these draw-backs, we developed a decoupled viewpoint control solution for a humanoid platform which allows visual feedback with low-latency and artificially increases the camera's FOV range to match that of the operator's headset. Our novel solution uses SLAM technology to enhance the visual feedback from a reconstructed mesh, complementing the areas that are not covered by the visual feedback from the robot. The visual feedback is presented as a point cloud in real-time to the operator. As a result, the operator is fed with real-time vision from the robot's head orientation by observing the pose of the point cloud. Balancing this kind of awareness and immersion is important in virtual reality based teleoperation, considering the safety and robustness of the control system. An experiment shows that the effectiveness of our solution.
Most consumer-grade digital cameras can only capture a limited range of luminance in real-world scenes due to sensor constraints. Besides, noise and quantization errors are often introduced in the imaging process. In ...
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Edge enabled Industrial Internet of Things (IIoT) platform is of great significance to accelerate the development of smart industry. However, with the dramatic increase in real-time IIoT applications, it is a great ch...
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The short-term hydrothermal scheduling (STHS) is a complex non-linear, non-convex and high-dimensional mathematical optimization problem. Due to the fact that the original chimp optimization algorithm (ChOA) is likely...
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We aim at accelerating super-resolution (SR) networks on large images (2K-8K). The large images are usually decomposed into small sub-images in practical usages. Based on this processing, we found that different image...
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