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Predicting circRNA-Disease Associations by Using Multi-Biomolecular Networks Based on Variational Graph Auto-Encoder with Attention Mechanism

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Chinese Journal of Electronics 2024年第6期33卷 1526-1537页

作者： Jing YANG Xiujuan LEI Yi PAN School of Computer Science Shaanxi Normal University Faculty of Computer Science and Control Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of Sciences Shenzhen Key Laboratory of Intelligent Bioinformatics Shenzhen Institute of Advanced Technology

CircRNA-disease association(CDA) can provide a new direction for the treatment of diseases. However,traditional biological experiment is time-consuming and expensive, this urges us to propose the reliable computational model to predict the associations between circRNAs and diseases. And there is existing more and more evidence indicates that the combination of multi-biomolecular information can improve the prediction accuracy. We propose a novel computational model for CDA prediction named MBCDA, we collect the multi-biomolecular information including circRNA, disease, miRNA and lncRNA based on 6 databases, and construct three heterogeneous network among them, then the multi-heads graph attention networks are applied to these three networks to extract the features of circRNAs and diseases from different views, the obtained features are put into variational graph auto-encoder(VGAE) network to learn the latent distributions of the nodes, a fully connected neural network is adopted to further process the output of VGAE and uses sigmoid function to obtain the predicted probabilities of circRNA-disease *** a result, MBCDA achieved the values of AUC and AUPR under 5-fold cross-validation of 0.893 and 0.887. MBCDA was applied to the analysis of the top-25 predicted associations between circRNAs and diseases, these experimental results show that our proposed MBCDA is a powerful computational model for CDA prediction.

关键词： Knowledge engineering Attention mechanisms Computational modeling Biological system modeling Predictive models Feature extraction Heterogeneous networks Topology Data mining Diseases

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Highly Efficient Back‑End‑of‑Line Compatible Flexible Si‑Based Optical Memristive Crossbar Array for Edge Neuromorphic Physiological Signal Processing and Bionic Machine Vision

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Nano-Micro Letters 2024年第11期16卷 323-339页

作者： Dayanand Kumar Hanrui Li Dhananjay D.Kumbhar Manoj Kumar Rajbhar Uttam Kumar Das Abdul Momin Syed Georgian Melinte Nazek El‑Atab Smart Advanced Memory Devices and Applications(SAMA)LaboratoryElectrical and Computer EngineeringComputer Electrical Mathematical Science and EngineeringKing Abdullah University of Science and Technology(KAUST)23955‑6900 ThuwalSaudi Arabia

The emergence of the Internet-of-Things is anticipated to create a vast market for what are known as smart edge devices,opening numerous opportunities across countless domains,including personalized healthcare and advanced *** 3D integration,edge devices can achieve unprecedented miniaturization while simultaneously boosting processing power and minimizing energy ***,we demonstrate a back-end-of-line compatible optoelectronic synapse with a transfer learning method on health care applications,including electroencephalogram(EEG)-based seizure prediction,electromyography(EMG)-based gesture recognition,and electrocardiogram(ECG)-based arrhythmia *** experiments on three biomedical datasets,we observe the classification accuracy improvement for the pretrained model with 2.93%on EEG,4.90%on ECG,and 7.92%on EMG,*** optical programming property of the device enables an ultralow power(2.8×10^(-13) J)fine-tuning process and offers solutions for patient-specific issues in edge computing ***,the device exhibits impressive light-sensitive characteristics that enable a range of light-triggered synaptic functions,making it promising for neuromorphic vision *** display the benefits of these intricate synaptic properties,a 5×5 optoelectronic synapse array is developed,effectively simulating human visual perception and memory *** proposed flexible optoelectronic synapse holds immense potential for advancing the fields of neuromorphic physiological signal processing and artificial visual systems in wearable applications.

关键词： Neuromorphic computing Electrophysiological signal Artificial vision system Image recognition Memristor

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A Review of Intelligent Configuration and Its Security for Complex Networks

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Chinese Journal of Electronics 2024年第4期33卷 920-947页

作者： Yue ZHAO Bin YANG Fei TENG Xianhua NIU Ning HU Bo TIAN Science and Technology on Communication Security Laboratory School of Computer and Information Engineering Chuzhou University School of Computing and Artificial Intelligence Southwest Jiaotong University School of Computer and Software Engineering Xihua University Cyberspace Institute of Advanced Technology Guangzhou University

Complex networks are becoming more complex because of the use of many components with diverse technologies. In fact, manual configuration that makes each component interoperable has breed latent danger to system security. There is still no comprehensive review of these studies and prospects for further research. According to the complexity of component configuration and difficulty of security assurance in typical complex networks, this paper systematically reviews the abstract models and formal analysis methods required for intelligent configuration of complex networks, specifically analyzes, and compares the current key technologies such as configuration semantic awareness, automatic generation of security configuration, dynamic deployment, and verification evaluation. These technologies can effectively improve the security of complex networks intelligent configuration and reduce the complexity of operation and maintenance. This paper also summarizes the mainstream construction methods of complex networks configuration and its security test environment and detection index system, which lays a theoretical foundation for the formation of the comprehensive effectiveness verification capability of configuration security. The whole lifecycle management system of configuration security process proposed in this paper provides an important technical reference for reducing the complexity of network operation and maintenance and improving network security.

关键词： Complex networks Intelligent configuration Configuration security Software defined network Lifecycle management

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Etching-free pixel definition in InGaN green micro-LEDs

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Light(Science & Applications) 2024年第8期13卷 1655-1665页

作者： Zhiyuan Liu Yi Lu Haicheng Cao Glen Isaac Maciel Garcia Tingang Liu Xiao Tang Na Xiao Raul Aguileta Vazquez Mingtao Nong Xiaohang Li Advanced Semiconductor Laboratory Electrical and Computer Engineering ProgramCEMSE DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Kingdom of Saudi Arabia

The traditional plasma etching process for defining micro-LED pixels could lead to significant sidewall *** near sidewall regions act as non-radiative recombination centers and paths for current leakage,significantly deteriorating device *** this study,we demonstrated a novel selective thermal oxidation(STO)method that allowed pixel definition without undergoing plasma damage and subsequent dielectric *** annealing in ambient air oxidized and reshaped the LED structure,such as p-layers and InGaN/GaN multiple quantum ***,the pixel areas beneath the pre-deposited SiO_(2)layer were selectively and effectively *** was demonstrated that prolonged thermal annealing time enhanced the insulating properties of the oxide,significantly reducing LED leakage ***,applying a thicker SiO_(2)protective layer minimized device resistance and boosted device efficiency *** the STO method,InGaN green micro-LED arrays with 50-,30-,and 10-μm pixel sizes were manufactured and *** results indicated that after 4 h of air annealing and with a 3.5-μm SiO_(2)protective layer,the 10-μm pixel array exhibited leakage currents density 1.2×10^(-6)A/cm^(2)at-10 V voltage and a peak on-wafer external quantum efficiency of~6.48%.This work suggests that the STO method could become an effective approach for future micro-LED manufacturing to mitigate adverse LED efficiency size effects due to the plasma etching and improve device ***-LEDs fabricated through the STO method can be applied to micro-displays,visible light communication,and optical interconnect-based *** planar pixel geometry will provide more possibilities for the monolithic integration of driving circuits with ***,the STO method is not limited to micro-LED fabrication and can be extended to design other III-nitride devices,such as photodetectors,laser diodes,high-electron-mobility transistors

关键词： annealing protective quantum

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The fNIRS-based Emotion Recognition by Spatial Transformer and WGAN Data Augmentation Towards Developing A Novel Affective BCI

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IEEE Transactions on Affective Computing 2024年第2期16卷 875-890页

作者： Si, Xiaopeng Huang, He Yu, Jiayue Ming, Dong Tianjin University Academy of Medical Engineering and Translational Medicine State Key Laboratory of Advanced Medical Materials and Devices Haihe Laboratory of Brain-computer Interaction and Human-machine Integration Tianjin Key Laboratory of Brain Science and Neural Engineering Institute of Applied Psychology Tianjin300072 China Tianjin University Academy of Medical Engineering and Translational Medicine State Key Laboratory of Advanced Medical Materials and Devices Haihe Laboratory of Brain-computer Interaction and Human-machine Integration Tianjin Key Laboratory of Brain Science and Neural Engineering Tianjin300072 China

The affective brain-computer interface (aBCI) facilitates the objective identification or regulation of human emotions. Current aBCI mainly relies on electroencephalography (EEG). However, research shows that emotions involve a large-scale distributed brain network. Compared to electroencephalography (EEG), functional near-infrared spectroscopy (fNIRS) offers a higher spatial resolution. It holds greater potential in capturing emotional spatial information, which may foster the development of new affective Brain-computer Interfaces (aBCI). We proposed a novel self-attention-based deep-learning transformer language model for fNIRS cross-subject emotion recognition, which could automatically learn the emotion's spatial attention weight information with strong interpretability. Besides, we performed data augmentation by introducing the wasserstein generative adversarial networks (WGAN). Results showed: (1) We achieved 84% three-category cross-subject emotion decoding accuracy. The spatial transformer module and WGAN improved the accuracy by 12.8% and 4.3%, respectively. (2) Compared with cutting-edge fNIRS research, we led by 10% in three-category decoding accuracy. (3) Compared with cutting-edge EEG research, we lead by 28% in arousal decoding accuracy, 10% in valence decoding accuracy, and 2% in three-category decoding accuracy. (4) Besides, our approach holds the potential to uncover the brain's spatial encoding mechanism of human emotion processing, providing a new direction for building interpretable artificial intelligence models. © 2010-2012 IEEE.

关键词： Near infrared spectroscopy

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Multi-Scale Time Series Segmentation Network Based on Eddy Current Testing for Detecting Surface Metal Defects

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IEEE/CAA Journal of Automatica Sinica 2025年第3期12卷 528-538页

作者： Xiaorui Li Xiaojuan Ban Haoran Qiao Zhaolin Yuan Hong-Ning Dai Chao Yao Yu Guo Mohammad S.Obaidat George Q.Huang the School of Intelligence Science and Technology University of Science and Technology Beijing the Beijing Advanced Innovation Center for Materials Genome Engineering the Key Laboratory of Intelligent Bionic Unmanned Systems and the Institute of Materials Intelligent Technology Liaoning Academy of Materials IEEE the Department of Computer Science Hong Kong Baptist University the School of Computer and Communication Engineering Key Laboratory of Advanced Materials and Devices for Post-Moore Chips Ministry of Education University of Science and Technology Beijing the Beijing Advanced Innovation Center for Materials Genome Engineering University of Science and Technology Beijing the School of Computer and Communication Engineering University of Science and Technology Beijing the King Abdullah Ⅱ School of Information Technology The University of Jordan the Department of Computational Intelligence the School of Computing SRM University the School of Engineering The Amity University The Hong Kong Polytechnic University

In high-risk industrial environments like nuclear power plants, precise defect identification and localization are essential for maintaining production stability and safety. However, the complexity of such a harsh environment leads to significant variations in the shape and size of the defects. To address this challenge, we propose the multivariate time series segmentation network(MSSN), which adopts a multiscale convolutional network with multi-stage and depth-separable convolutions for efficient feature extraction through variable-length templates. To tackle the classification difficulty caused by structural signal variance, MSSN employs logarithmic normalization to adjust instance distributions. Furthermore, it integrates classification with smoothing loss functions to accurately identify defect segments amid similar structural and defect signal subsequences. Our algorithm evaluated on both the Mackey-Glass dataset and industrial dataset achieves over 95% localization and demonstrates the capture capability on the synthetic dataset. In a nuclear plant's heat transfer tube dataset, it captures 90% of defect instances with75% middle localization F1 score.

关键词： Eddy current testing nondestructive testing semantic segmentation time series analysis

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Design of a Remote Controlled Puppet Robot Imitating a Manual Driven Puppet Using Deep Learning Pose Detection 12

Design of a Remote Controlled Puppet Robot Imitating a Manua...

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12th RSI International Conference on Robotics and Mechatronics, ICRoM 2024

作者： Hamzeh, Hamed Shahroozi, Kiarash Nabipour, Ahmad Kazemi, Parham Malek-Zahedi, Mohammad Hallajian, Mehdi Moradia, Hadi School of Electrical and Computer Engineering College of Engineering University of Tehran Advanced Robotics and Intelligent Systems Laboratory Iran

ISBN: (纸本)9798331529734

Traditional puppet manipulation systems often require human operators to be physically present in tight and cramped locations. This leads to challenges in the positioning and effective operation of puppets, particularly in the presence of children in educational settings. In this paper, we present the design, development, and integration of a cost-effective robotic system for remotely manipulating puppets in real-time. Additionally, the system integrates a YOLOv8 Pose Detection model, trained on a custom dataset with an accuracy of 91.4%, enabling real-time gesture recognition and allowing the robot to be controlled by imitating the motions of a manually operated puppet. The system demonstrates the potential for many applications, including interactive entertainment, teleoperation, and education. © 2024 IEEE.

关键词： Gesture recognition

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Enhanced Privacy-Preserving WiFi Fingerprint Localization from CL Encryption

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Chinese Journal of Electronics 2024年第6期33卷 1435-1446页

作者： Zhiwei WANG Qiuchi ZHU Zhenqi ZHANG School of Computer Nanjing University of Posts and Telecommunications State Key Laboratory of Public Big Data Guizhou University Advanced Cryptography and System Security Key Laboratory of Sichuan Province Chengdu University of Information Engineering Key Laboratory of Computational Science and Application of Hainan Province Hainan Normal University

The WiFi fingerprint-based localization method is considered one of the most popular techniques for indoor localization. In INFOCOM'14, Li et al. proposed a wireless fidelity(WiFi) fingerprint localization system based on Paillier encryption, which is claimed to protect both client C 's location privacy and service provider S's database privacy. However, Yang et al. presented a practical data privacy attack in INFOCOM'18, which allows a polynomial time attacker to obtain S's database. We propose a novel WiFi fingerprint localization system based on CastagnosLaguillaumie(CL) encryption, which has a trustless setup and is efficient due to the excellent properties of CL encryption. To prevent Yang et al.'s attack, the system requires that S selects only the locations from its database that can receive the nonzero signals from all the available access points in C 's nonzero fingerprint in order to determine C's location. Security analysis shows that our scheme is secure under Li et al.'s threat model. Furthermore, to enhance the security level of privacy-preserving WiFi fingerprint localization scheme based on CL encryption, we propose a secure and efficient zero-knowledge proof protocol for the discrete logarithm relations in C's encrypted localization queries.

关键词： Location awareness Threat modeling Data privacy Protocols Databases Fingerprint recognition Trustless services Encryption Servers Wireless fidelity

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Artificial visual perception neural system using a solution-processable MoS_(2)-based in-memory light sensor

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Light(Science & Applications) 2023年第8期12卷 1583-1594页

作者： Dayanand Kumar Lana Joharji Hanrui Li Ayman Rezk Ammar Nayfeh Nazek El-Atab Smart Advanced Memory Devices and Applications(SAMA)LaboratoryElectrical and Computer Engineering ProgramComputer Electrical Mathematical Science and Engineering DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal 23955Kingdom of Saudi Arabia Department of Electrical Engineering and Computer Science Khalifa UniversityAbu Dhabi 127788United Arab Emirates

Optoelectronic devices are advantageous in in-memory light sensing for visual information processing,recognition,and storage in an energy-efficient ***,in-memory light sensors have been proposed to improve the energy,area,and time efficiencies of neuromorphic computing *** study is primarily focused on the development of a single sensing-storage-processing node based on a two-terminal solution-processable MoS2 metal-oxide-semiconductor(MOS)charge-trapping memory structure—the basic structure for charge-coupled devices(CCD)—and showing its suitability for in-memory light sensing and artificial visual *** memory window of the device increased from 2.8 V to more than 6V when the device was irradiated with optical lights of different wavelengths during the program ***,the charge retention capability of the device at a high temperature(100 ℃)was enhanced from 36 to 64%when exposed to a light wavelength of 400 *** larger shift in the threshold voltage with an increasing operating voltage confirmed that more charges were trapped at the Al_(2)O_(3)/MoS_(2) interface and in the MoS_(2) layer.A small convolutional neural network was proposed to measure the optical sensing and electrical programming abilities of the *** array simulation received optical images transmitted using a blue light wavelength and performed inference computation to process and recognize the images with 91%*** study is a significant step toward the development of optoelectronic MOS memory devices for neuromorphic visual perception,adaptive parallel processing networks for in-memory light sensing,and smart CCD cameras with artificial visual perception capabilities.

关键词： visual neural process

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Speed Harmonic based Saturation Free Inductance Modeling and Estimation of Interior PMSM Using Measurements Under One Load Condition

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CES Transactions on Electrical Machines and Systems 2025年第1期9卷 91-99页

作者： Guodong Feng Yuting Lu Zhe Tong Beichen Ding Guishan Yan Chunyan Lai the School of Intelligent Systems Engineering Sun Yat-sen UniversityShenzhenChina the School of Advanced Manufacturing Sun Yat-sen University the Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) China the Department of Electrical and Computer Engineering Concordia UniversityQCCanada

For permanent magnet synchronous machines(PMSMs),accurate inductance is critical for control design and condition *** to magnetic saturation,existing methods require nonlinear saturation model and measurements from multiple load/current conditions,and the estimation is relying on the accuracy of saturation model and other machine parameters in the *** harmonic produced by harmonic currents is inductance-dependent,and thus this paper explores the use of magnitude and phase angle of the speed harmonic for accurate inductance *** estimation models are built based on either the magnitude or phase angle,and the inductances can be from d-axis voltage and the magnitude or phase angle,in which the filter influence in harmonic extraction is considered to ensure the estimation *** inductances can be estimated from the measurements under one load condition,which is free of saturation ***,the inductance estimation is robust to the change of other machine *** proposed approach can effectively improve estimation accuracy especially under the condition with low current *** and comparisons are conducted on a test PMSM to validate the proposed approach.

关键词： PMSM Inductance estimation Speed harmonic High frequency signal injection

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