We introduce a groundbreaking proof-of-concept for a novel glucose monitoring transducing mechanism,marking the first demonstration of a spore-forming microbial whole-cell sensing *** approach uses selective and sensi...
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We introduce a groundbreaking proof-of-concept for a novel glucose monitoring transducing mechanism,marking the first demonstration of a spore-forming microbial whole-cell sensing *** approach uses selective and sensitive germination of Bacillus subtilis spores in response to glucose in potassium-rich bodily fluids such as *** the rate of germination and the number of metabolically active germinating cells are directly proportional to glucose concentration,the electrogenic activity of these cells—manifested as electricity—serves as a self-powered transducing signal for glucose *** a microengineered,paper-based microbial fuel cell(MFC),these electrical power outputs are measurable and can be visually displayed through a compact interface,providing real-time *** dormant spores extend shelf-life,and the self-replicating bacteria ensure *** MFC demonstrated a remarkable sensitivity of 2.246µW·(log mM)^(-1)·cm^(-2) to glucose concentrations ranging from 0.2 to 10 mM,with a notably lower limit of detection at~0.07 *** sensor exhibited exceptional selectivity,accurately detecting glucose even in the presence of various *** analyses revealed that,unlike conventional enzymatic biosensors whose performance degrades significantly through time even when inactive,the spore-based MFC is stable for extended periods and promptly regains functionality when *** preliminary investigation indicates that the spore-forming microbial whole-cell sensing strategy holds considerable promise for efficient diabetes management and can be extended toward noninvasive wearable monitoring,overcoming critical challenges of current technologies and paving the way for advanced biosensing applications.
To tackle the energy crisis and climate change,wind farms are being heavily invested in across the *** China's coastal areas,there are abundant wind resources and numerous offshore wind farms are being *** secure ...
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To tackle the energy crisis and climate change,wind farms are being heavily invested in across the *** China's coastal areas,there are abundant wind resources and numerous offshore wind farms are being *** secure operation of these wind farms may suffer from typhoons,and researchers have studied power system operation and resilience enhancement in typhoon ***,the intricate movement of a typhoon makes it challenging to evaluate its spatial-temporal *** published papers only consider predefined typhoon trajectories neglecting *** address this challenge,this study proposes a stochastic unit commitment model that incorporates high-penetration offshore wind power generation in typhoon *** adopts a data-driven method to describe the uncertainties of typhoon trajectories and considers the realistic anti-typhoon mode in offshore wind farms.A two-stage stochastic unit commitment model is designed to enhance power system resilience in typhoon *** formulate the model into a mixed-integer linear programming problem and then solve it based on the computationally-efficient progressive hedging algorithm(PHA).Finally,numerical experiments validate the effectiveness of the proposed method.
Bilateral teleoperation system is referred to as a promising technology to extend human actions and intelligence to manipulating objects *** the tracking control of teleoperation systems,velocity measurements are nece...
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Bilateral teleoperation system is referred to as a promising technology to extend human actions and intelligence to manipulating objects *** the tracking control of teleoperation systems,velocity measurements are necessary to provide feedback ***,due to hardware technology and cost constraints,the velocity measurements are not always *** addition,the time-varying communication delay makes it challenging to achieve tracking *** paper provides a solution to the issue of real-time tracking for teleoperation systems,subjected to unavailable velocity signals and time-varying communication *** order to estimate the velocity information,immersion and invariance(I&I)technique is employed to develop an exponential stability velocity *** the proposed velocity observer,a linear relationship between position and observation state is constructed,through which the need of solving partial differential and certain integral equations can be ***,the mean value theorem is exploited to separate the observation error terms,and hence,all functions in our observer can be analytically *** the estimated velocity information,a slave-torque feedback control law is presented.A novel Lyapunov-Krasovskii functional is constructed to establish asymptotic tracking *** particular,the relationship between the controller design parameters and the allowable maximum delay values is ***,simulation and experimental results reveal that the proposed velocity observer and controller can guarantee that the observation errors and tracking error converge to zero.
Wind energy conversion system (WECS) is stochastic in nature and has low inertia leading to grid voltage instability, poor reactive power compensation and most importantly fault susceptibility. Variable speed WECS suc...
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Thyroid disorders represent a significant global health challenge with hypothyroidism and hyperthyroidism as two common conditions arising from dysfunction in the thyroid *** and timely diagnosis of these disorders is...
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Thyroid disorders represent a significant global health challenge with hypothyroidism and hyperthyroidism as two common conditions arising from dysfunction in the thyroid *** and timely diagnosis of these disorders is crucial for effective treatment and patient *** research introduces a comprehensive approach to improve the accuracy of thyroid disorder diagnosis through the integration of ensemble stacking and advanced feature selection *** forward feature selection,sequential backward feature elimination,and bidirectional feature elimination are investigated in this *** ensemble learning,random forest,adaptive boosting,and bagging classifiers are *** effectiveness of these techniques is evaluated using two different datasets obtained from the University of California Irvine-Machine Learning Repository,both of which undergo preprocessing steps,including outlier removal,addressing missing data,data cleansing,and feature *** experimentation demonstrates the remarkable success of proposed ensemble stacking and bidirectional feature elimination achieving 100%and 99.86%accuracy in identifying hyperthyroidism and hypothyroidism,*** enhancing detection accuracy,the ensemble stacking model also demonstrated a streamlined computational complexity which is pivotal for practical medical *** significantly outperformed existing studies with similar objectives underscoring the viability and effectiveness of the proposed *** research offers an innovative perspective and sets the platform for improved thyroid disorder diagnosis with broader implications for healthcare and patient well-being.
With the increase in users' service diversity and demand for quality of experience (QoE), the utilization of low earth orbit (LEO) satellite networks for assisted or independent offloading of computation tasks has...
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The study examined various filtering methods applied to ECG signals;the MIT-BIH Arrhythmia dataset included two channels to reduce noise and artifacts while maintaining critical waveform characteristics. Initial filte...
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This paper investigates the rate outage constrained (ROC) energy efficiency (EE) under multiple-input single-output (MISO) interference channels, where only channel distribution information (CDI) is available at base ...
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