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Scalable Electrophysiology of Millimeter-Scale Animals with Electrode Devices

Biomedical Engineering Frontiers 2023年第1期4卷 3-20页

作者： Kairu Dong Wen-Che Liu Yuyan Su Yidan Lyu Hao Huang Nenggan Zheng John A.Rogers Kewang Nan College of Pharmaceutical Sciences Zhejiang UniversityHangzhou 310058China National Key Laboratory of Advanced Drug Delivery and Release Systems Zhejiang UniversityHangzhou 310058China College of Biomedical Engineering&Instrument Science Zhejiang UniversityHangzhou310027China Department of Gastroenterology Brigham and Women’s HospitalHarvard Medical SchoolBostonMA 02115USA College of Chemical and Biological Engineering Zhejiang UniversityHangzhou 310058China Qiushi Academy for Advanced Studies Zhejiang UniversityHangzhou 310027China College of Computer Science and Technology Zhejiang UniversityHangzhou 310027China State Key Lab of Brain-Machine Intelligence Zhejiang UniversityHangzhou 310058China CCAI by MOE and Zhejiang Provincial Government(ZJU) Hangzhou 310027China Querrey Simpson Institute for Bioelectronics Northwestern UniversityEvanstonIL 60208USA Department of Biomedical Engineering Northwestern UniversityEvanstonIL 60208USA Department of Materials Science and Engineering Northwestern UniversityEvanstonIL 60208USA Department of Mechanical Engineering Northwestern UniversityEvanstonIL 60208USA Jinhua Institute of Zhejiang University Jinhua 321299China

Millimeter-scale animals such as Caenorhabditis elegans,Drosophila larvae,zebrafish,and bees serve as powerful model organisms in the fields of neurobiology and *** methods exist for recording large-scale electrophysiological signals from these *** approaches often lack,however,real-time,uninterrupted investigations due to their rigid constructs,geometric constraints,and mechanical mismatch in integration with soft *** recent research establishes the foundations for 3-dimensional flexible bioelectronic interfaces that incorporate microfabricated components and nanoelectronic function with adjustable mechanical properties and multidimensional variability,offering unique capabilities for chronic,stable interrogation and stimulation of millimeter-scale animals and miniature tissue *** review summarizes the most advanced technologies for electrophysiological studies,based on methods of 3-dimensional flexible bioelectronics.A concluding section addresses the challenges of these devices in achieving freestanding,robust,and multifunctional biointerfaces.

关键词： offering recording millimeter

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RCGA-Net: An Improved Multi-hybrid Attention Mechanism Network in Biomedical Image Segmentation

RCGA-Net: An Improved Multi-hybrid Attention Mechanism Netwo...

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2021 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2021

作者： Xiao, Feng Shen, Cong Chen, Yu Yang, Tian Chen, Shengyong Liao, Zhijun Tang, Jijun Tianjin University of Technology School of Computer Science and Engineering Tianjin China Engineering Research Center of Learning-Based Intelligent System Ministry of Education Tianjin China School of Basic Medical Sciences Fujian Medical University Fujian Fuzhou China College of Intelligence and Computing Tianjin University Tianjin China Key Laboratory of Systems Bioengineering Ministry of Education Tianjin China Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Guangdong Shenzhen China Department of Computer Science and Engineering University of South Carolina ColumbiaSC United States

ISBN: (纸本)9781665401265

Drawing support from an effective Medical Image Segmentation (MIS) is conducive to a substantial diagnostic basis for the physicians to identify the focus lesion in the patient body and give the subsequent clinical assessment of the patient status. Although various works have tried the challenging quantitative analysis problem, it is still difficult to conduct precise automatic segmentation, especially the soft tissue organs. In this decade, with the increased amount of available datasets, deep learning-based networks have achieved remarkable performance in image processing. Inspired by the state-of-the-art deep learning works, in this paper, we propose an end-to-end multi-layer network named RCGA-Net. It consists of an encoder-decoder backbone that integrates a coordinate attention mechanism based on space and channel and a global context extraction module to highlight more valuable information. To evaluate the performance of RCGA-Net, we apply it to different kinds of clinical and experimental MIS tasks to testify its generalization ability. Extensive experiments represent that our schema has taken the outperform or compatible results among the comparison methods group. Specifically, the numeric result of RCGA-Net on the pulmonary dataset has achieved a 99.12% optimum F1-score. © 2021 IEEE.

关键词： Diagnosis

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Transformative Sport Science Using Social Media as a Collaboration Tool 7

Transformative Sport Science Using Social Media as a Collabo...

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7th International Conference on ICT for Smart Society, ICISS 2020

作者： Oktavia, Tanty Gaol, Ford Lumban Hosoda, Takaaki Syahir, Arsyan Bina Nusantara University School of Information Systems Information Systems Department Jakarta11480 Indonesia Bina Nusantara University Binus Graduate Program - Doctor of Computer Science Computer Science Department Jakarta11480 Indonesia Advanced Institute of Industrial Technology Decision Science Department Tokyo Japan Bina Nusantara University BINUS Graduate Program - Master of Information Systems Management Information Systems Management Department Jakarta11480 Indonesia

ISBN: (纸本)9781665404228

Sports science can have a significant and positive impact on coaches and athletes, as well as for the professional sports organization. According to this situation, more and more organizations are competing to implement sports science as the monitoring systems. Along with the development of technology, it becomes easier for humans to carry out their activities, including communication with each other. Advances in the field of communication technologies have led to the use of social networks to support all activity. With social media, all kinds of information that people want to search for can be found easily. Social networks have their uniqueness in their characteristics. Like LINE has free calling and video calling features, while Instagram has features like Instagram Story, where users can document their activities in the form of photos or recordings. By all the characteristics of social networks, it will support the activity of sports science. The methodology of this research focused on quantitative research based on the T-test approach. The result shows that social media involvement can significantly support collaboration in sports science, so it can increase people's motivation to interact with other participants in sport organizations. © 2020 IEEE.

关键词： Sports

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Abnormal Data Cleaning for Wind Turbines by Image Segmentation Based on Active Shape Model and Class Uncertainty

SSRN

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SSRN 2022年

作者： Liang, Guoyuan Su, Yahao Wu, Xinyu Ma, Jiajun Long, Huan Song, Zhe Guangdong Provincial Key Lab of Robotics and Intelligent System Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Guangdong Province Shenzhen China Guangdong Provincial Key Laboratory of Computer Vision and Virtual Reality Technology Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Guangdong Province Shenzhen China Guangdong-Hong Kong-Macao Joint Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Guangdong Province Shenzhen China School of Electrical Engineering Southeast University Jiang Su Province Nanjing China School of Business Nanjing University Jiang Su Province Nanjing China

Wind power curve describes the relationship between wind speed and output power of wind turbine, which may be contaminated due to various unexpected factors. Following the idea of image segmentation in our previous work, in this paper, we propose a novel image-based abnormal data cleaning algorithm aiming to provide high quality data for wind power curve modeling and relevant applications. For image binarization, a multiscale space is built to determine the optimal scale at which the most stable as well as informative shape representations are extracted. The Active Shape Model is utilized to model the power curve shape and generate a set of segmentation candidates for filtering abnormal data. To measure the cost of each candidate, the Class Uncertainty map based on dual feature images is built. And eventually the optimal segmentation boundary is determined by the optimization in the energy space. A series of comparative experiments conducted over the real-world datasets of 37 wind turbines have validated the superior performance of the proposed algorithm. © 2022, The Authors. All rights reserved.

关键词： Wind power

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Structured probabilistic end-to-end learning from crowds 29

Structured probabilistic end-to-end learning from crowds

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29th International Joint Conference on Artificial Intelligence, IJCAI 2020

作者： Chen, Zhijun Wang, Huimin Sun, Hailong Chen, Pengpeng Han, Tao Liu, Xudong Yang, Jie SKLSDE Lab School of Computer Science and Engineering Beihang University China Beijing Advanced Innovation Center for Big Data and Brain Computing Beihang University China Web Information Systems Delft University of Technology Netherlands

ISBN: (纸本)9780999241165

End-to-end learning from crowds has recently been introduced as an EM-free approach to training deep neural networks directly from noisy crowdsourced annotations. It models the relationship between true labels and annotations with a specific type of neural layer, termed as the crowd layer, which can be trained using pure backpropagation. Parameters of the crowd layer, however, can hardly be interpreted as annotator reliability, as compared with the more principled probabilistic approach. The lack of probabilistic interpretation further prevents extensions of the approach to account for important factors of annotation processes, e.g., instance difficulty. This paper presents SpeeLFC, a structured probabilistic model that incorporates the constraints of probability axioms for parameters of the crowd layer, which allows to explicitly model annotator reliability while benefiting from the end-to-end training of neural networks. Moreover, we propose SpeeLFC-D, which further takes into account instance difficulty. Extensive validation on real-world datasets shows that our methods improve the state-of-the-art. © 2020 Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.

关键词： Deep neural networks

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Adaptive Wavelet Filters as Practical Texture Feature Amplifiers for Parkinson’s Disease Screening in OCT

arXiv

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arXiv 2025年

作者： Zhang, Xiaoqing Shi, Hanfeng Li, Xiangyu Ye, Haili Xu, Tao Li, Na Hu, Yan Lv, Fan Chen, Jiangfan Liu, Jiang Center for High Performance Computing and Shenzhen Key Laboratory of Intelligent Bioinformatics Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China Research Institute of Trustworthy Autonomous Systems Department of Computer Science and Engineering Southern University of Science and Technology Shenzhen518055 China State Key Laboratory of Ophthalmology Optometry and Vision Science Wenzhou Medical University Wenzhou China Centre for Computational Science and Mathematical Modelling Coventry University Coventry United Kingdom School of Computer Science University of Nottingham Ningbo China Ningbo315100 China School of Ophthalmology and Optometry Wenzhou Medical University Wenzhou325035 China Department of Electronic and Information Engineering Changchun University Changchun130022 China

Parkinson’s disease (PD) is a prevalent neurodegenerative disorder globally. The eye’s retina is an extension of the brain and has great potential in PD screening. Recent studies have suggested that texture features extracted from retinal layers can be adopted as biomarkers for PD diagnosis under optical coherence tomography (OCT) images. Frequency domain learning techniques can enhance the feature representations of deep neural networks (DNNs) by decomposing frequency components involving rich texture features. Additionally, previous works have not exploited texture features for automated PD screening in OCT. Motivated by the above analysis, we propose a novel Adaptive Wavelet Filter (AWF) that serves as the Practical Texture Feature Amplifier to fully leverage the merits of texture features to boost the PD screening performance of DNNs with the aid of frequency domain learning. Specifically, AWF first enhances texture feature representation diversities via channel mixer, then emphasizes informative texture feature representations with the well-designed adaptive wavelet filtering token mixer. By combining the AWFs with the DNN stem, AWFNet is constructed for automated PD screening. Additionally, we introduce a novel Balanced Confidence (BC) Loss by mining the potential of sample-wise predicted probabilities of all classes and class frequency prior, to further boost the PD screening performance and trustworthiness of AWFNet. The extensive experiments manifest the superiority of our AWFNet and BC over state-of-the-art methods in terms of PD screening performance and trustworthiness. © 2025, CC BY-NC-SA.

关键词： Neurodegenerative diseases

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Computing Power in the Sky: Digital Twin-assisted Collaborative Computing with Multi-UAV Networks

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IEEE Transactions on Vehicular technology 2025年

作者： Wang, Chao Han, Yu Zhang, Long Jia, Ziye Zhang, Hongliang Hong, Choong Seon Han, Zhu Hebei University of Engineering School of Information and Electrical Engineering Handan056038 China Qilu University of Technology Shandong Academy of Sciences Key Laboratory of Computing Power Network and Information Security Ministry of Education Jinan250014 China Nanjing University of Aeronautics and Astronautics College of Electronic and Information Engineering Nanjing211106 China Southeast University National Mobile Communications Research Laboratory Jiangsu Nanjing211111 China Peking University State Key Laboratory of Advanced Optical Communication Systems and Networks School of Electronics Beijing100871 China Kyung Hee University Department of Computer Science and Engineering Gyeonggi-do Yongin-si17104 Korea Republic of University of Houston Department of Electrical and Computer Engineering HoustonTX77004 United States Kyung Hee University Department of Computer Science and Engineering Seoul446-701 Korea Republic of

The collaboration of computing powers (CPs) among unmanned aerial vehicles (UAVs)-mounted edge servers is essential to handle data-intensive tasks of user equipments (UEs). This paper presents a multi-UAV computing power network (CPN) that orchestrates the CP resources of edge servers to cooperatively process tasks through collaborative computing. Due to the frequent interactions among edge servers and the increased complexities for large-scale task executions, we propose a digital twin (DT)-driven multi-UAV CPN framework, where the aerial DT network is created as a digital replica of the multi-UAV network to assist collaborative computing. A joint optimization problem of the service association, offloading power control, task partitions, CP allocation, and UAV trajectory design is formulated to minimize the long-term average delay of UEs. We use the Lyapunov technique to tackle the long-term energy constraint, forming a tractable optimization problem, which is modeled as a Markov decision process to balance the UAV's deficit queue stability and the UE's task completion delay. A hybrid soft actor-critic based deep reinforcement learning algorithm is developed to optimize the joint design by sampling the hybrid action from the Gumbel and Gaussian distributions. Simulation results verify that the multi-UAV CPN contributes to significant performance gains when supported by DTs. © 2025 IEEE.

关键词： Markov processes

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Channel performance estimations with extended channel probing 21

Channel performance estimations with extended channel probin...

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21. ITG-Fachtagung Photonische Netze - 21st ITG Conference on Photonic Networks

作者： Kaeval, Kaida Elbers, Jörg-Peter Grieβer, Helmut Tikas, Marko Grobe, Klaus Jervan, Gert Advanced Technology ADVA Optical Networking SE Martinsried Germany Transmission Networks Tele2 Estonia AS Tallinn Estonia Global Sustainability ADVA Optical Networking SE Martinsried Germany Department of Computer Systems Tallinn University of Technology Tallinn Estonia

ISBN: (纸本)9783800754243

We test the concept of extended channel probing in a Optical Spectrum as a Service scenario in coherent optimized flex-grid long-haul and 10Gbit/s OOK optimized 100-GHz fixed-grid dispersion managed legacy DWDM networks. An estimation accuracy better than ±0.1dB in GSNR implementation margin is obtained for both networks by using flexible coherent transceivers on lightpaths up to 822km on regional haul legacy network and up to 5738km on a long-haul network. We also explain, how to detect the operation regime of the channel by analyzing the received GSNR results from constant power spectral density (PSD) probing mode and constant signal power probing mode. © VDE VERLAG GMBH ∙ Berlin ∙ Offenbach

关键词： Optical communication

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Multiscale Convolutional Transformer with Diverse-aware Feature Learning for Motor Imagery EEG Decoding

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IEEE Transactions on Cognitive and Developmental systems 2025年

作者： Hang, Wenlong Wang, Junliang Liang, Shuang Lei, Baiying Wang, Qiong Li, Guanglin Chen, Badong Qin, Jing Nanjing Tech University College of Computer Nanjing211816 China Nanjing Tech University Information Engineering Nanjing211816 China Nanjing University of Posts and Telecommunications School of Internet of Things Nanjing210023 China Shenzhen University School of Biomedical Engineering Shenzhen518060 China Guangdong Provincial Key Laboratory of Computer Vision Shenzhen518055 China Virtual Reality Technology Shenzhen518055 China Guangdong-Hong Kong-Macao Joint Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen518055 China Shenzhen Institute of Advanced Technology Shenzhen518055 China Chinese Academy of Sciences Shenzhen518055 China Xi'an Jiaotong University Institute of Artificial Intelligence and Robotics Xi'an710049 China Hong Kong Polytechnic University School of Nursing Hung Hom Hong Kong

Electroencephalogram (EEG)-based motor imagery (MI) brain-computer interfaces (BCIs) have significant potential in improving motor function for neurorehabilitation. Despite recent advancements, learning diversified EEG features across different frequency ranges remains a significant challenge, as the homogenization of feature representations often limits the generalization capabilities of EEG decoding models for BCIs. In this paper, we propose a novel multiscale convolutional transformer framework for EEG decoding that integrates multiscale convolution, transformer, and diverse-aware feature learning scheme (MCTD) to tackle the above challenge. Specifically, we first capture multiple frequency features using dynamic one-dimensional temporal convolution with different kernel lengths. Subsequently, we incorporate convolutional layers and transformers with a contrastive learning scheme to extract discriminative local and global EEG features within a single frequency range. To mitigate the homogenization of features extracted from different frequency ranges, we propose a novel decorrelation regularization. It enables multiscale convolutional transformers produce less correlated features with each other, thereby enhancing the overall expressiveness of EEG decoding model. The performance of MCTD is evaluated on four public MI-based EEG datasets, including the BCI competition III 3a and IV 2a, the BNCI 2015- 001, and the OpenBMI. For the average Kappa/Accuracy scores, MCTD obtains improvements of 3.58%/2.68%, 3.09%/2.20%, 2.33%/1.54%, and 4.44%/2.22%, over the state-of-the-art method on four EEG datasets, respectively. Experimental results demonstrate that our method exhibits superior performance. © 2016 IEEE.

关键词： Brain computer interface

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Point-Based 3D Virtual Fixture Generating for Image-Guided and Robot-Assisted Surgery in Orthopedics*

Point-Based 3D Virtual Fixture Generating for Image-Guided a...

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IEEE/ASME (AIM) International Conference on advanced Intelligent Mechatronics

作者： Teng Li Armin Badre Hamid D. Taghirad Mahdi Tavakoli Department of Electrical and Computer Engineering Faculty of Engineering University of Alberta Edmonton Canada Western Upper Limb Facility Sturgeon Hospital St. Albert Canada Division of Orthopaedic Surgery Department of Surgery Faculty of Medicine & Dentistry University of Alberta Edmonton Canada Advanced Robotics and Automated Systems (ARAS) Faculty of Electrical Engineering K. N. Toosi University of Technology Tehran Iran

Virtual fixture (VF) has been playing a vital role in robot-assisted surgeries, such as guiding surgical tools’ movement and protecting a beating heart. In orthopedic surgery, preplanned images are often used in the operating room, on which planning curves might be drawn, for instance, to mark out the boundaries for osteophytes to be removed. These curves can be used to generate VF to assist in removing osteophytes during the operation. A challenge is that the hand-drawn curves usually have a random shape and cannot be mathematically represented by equations, thus most of the existing algorithms will not work in this scenario. In this paper, an algorithm of VF generating based on point clouds is presented, with which VF can be generated directly from cloud points, for example, point clouds of hand-drawn curves extracted from an image. The effectiveness of the VF algorithm is evaluated by a series of simulations and experiments. The VF algorithm is also tested in an image-based scenario and its effectiveness is demonstrated. The presented point-based VF algorithm is promising to be used in various applications in image-guided surgery to generate VF for objects with various shapes.

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