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arXiv 2018年

作者： Yang, Bo Ren, Shen Legara, Erika Fille Li, Zengxiang Ong, Edward Y.X. Lin, Louis Monterola, Christopher Complex Systems Group Institute of High Performance Computing A-STAR 138632 Singapore Institute of High Performance Computing Distributed Computing A-STAR 138632 Singapore Land Transport Division Ministry of Transport 119903 Singapore Asian Institute of Management Technology and Entrepreneurship School of Innovation Manila Philippines

We develop a numerical model using both artificial and empirical inputs to analyze taxi dynamics in an urban setting. More specifically, we quantify how the supply and demand for taxi services, the underlying road network, and the public acceptance of taxi ridesharing (TRS) affect the optimal number of taxis for a particular city, as well as commuters' average waiting time and trip time. Results reveal certain universal features of the taxi dynamics with real-time taxi-booking|that there is a well-defined transition between the oversaturated phase when demand exceeds supply, and the undersaturated phase when supply exceeds demand. The boundary between the two phases gives the optimal number of taxis a city should accommodate, given the specific demand, road network and commuter habits. Adding or removing taxis may affect commuter experience very differently in the two phases revealed. In the oversaturated phase the average waiting time is affected exponentially, while in the undersaturated phase it is affected sub-linearly. We analyze various factors that can shift the phase boundary, and show that an increased level of acceptance for TRS universally shifts the phase boundary by reducing the number of taxis needed. We discuss some of the useful insights on the benefits and costs of TRS, especially how under certain situations TRS will not only have economic benefits for commuters, but can also save the overall travel time for the shared parties, by significantly reducing the time commuters spend on waiting for taxis. Our simulations also suggest that simple artificial taxi systems can capture most of the universal features of the taxi dynamics. The relevance of the assumptions and the overall methodology are also illustrated using the empirical road network and taxi demand in Singapore. Copyright © 2018, The Authors. All rights reserved.

关键词： Taxicabs

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Strong in-plane anisotropy in the electronic structure of fixed-valence β−LuAlB4

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Physical Review B 2020年第8期102卷 081102(R)-081102(R)页

作者： Pascal Reiss Jordan Baglo Hong'En Tan Xiaoye Chen Sven Friedemann Kentaro Kuga F. Malte Grosche Satoru Nakatsuji Michael Sutherland Cavendish Laboratory University of Cambridge Cambridge CB3 0HE United Kingdom Clarendon Laboratory University of Oxford Oxford OX1 3PU United Kingdom Complex Systems Group Institute of High Performance Computing A*STAR Singapore 138632 HH Wills Laboratory University of Bristol Bristol BS8 1TL United Kingdom Institute for Solid State Physics University of Tokyo Kashiwa 277-8581 Japan CREST Japan Science and Technology Agency Kawaguchi Saitama 332-0012 Japan Department of Physics University of Tokyo Bunkyo-ku Tokyo 113-0033 Japan Trans-scale Quantum Science Institute University of Tokyo Bunkyo-ku Tokyo 113-0033 Japan

The origin of intrinsic quantum criticality in the heavy-fermion superconductor β−YbAlB4 has been attributed to strong Yb valence fluctuations and its peculiar crystal structure. Here, we assess these contributions individually by studying the isostructural but fixed-valence compound β−LuAlB4. Quantum oscillation measurements and density functional theory calculations reveal a Fermi surface in β−LuAlB4 markedly different from that of β−YbAlB4, consistent with a “large” Fermi surface in the latter. We also find an unexpected in-plane anisotropy of the electronic structure, in contrast to the isotropic Kondo hybridization in β−YbAlB4.

关键词： Electronic structure Fermi surface Kondo effect Quantum criticality Heavy-fermion systems Density functional theory Resistivity measurements Shubnikov-de Haas effect

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Practical security of continuous-variable quantum key distribution with reduced optical attenuation

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Physical Review A 2019年第1期100卷 012313-012313页

作者： Yi Zheng Peng Huang Anqi Huang Jinye Peng Guihua Zeng College of Information Science and Technology Northwest University Xi'an 710127 Shaanxi China State Key Laboratory of Advanced Optical Communication Systems and Networks and Center of Quantum Information Sensing and Processing Shanghai Jiao Tong University Shanghai 200240 China Institute for Quantum Information & State Key Laboratory of High Performance Computing College of Computer National University of Defense Technology Changsha 410073 China Greatwall Quantum Laboratory China Greatwall Technology Changsha 410205 China

In a practical continuous-variable quantum key distribution (CVQKD) system, the optical attenuator can adjust the Gaussian-modulated coherent states and the local oscillator signal to an optimal value for guaranteeing the security of the system and optimizing the performance of the system. However, the performance of the optical attenuator may deteriorate due to the intentional and unintentional damage of the device. In this paper, we investigate the practical security of a CVQKD system with reduced optical attenuation. We find that the secret key rate of the system may be overestimated based on the investigation of parameter estimation under the effects of reduced optical attenuation. This opens a security loophole for Eve to successfully perform an intercept-resend attack in a practical CVQKD system. To close this loophole, we add an optical fuse at Alice's output port and design a scheme to monitor the level of optical attenuation in real time, which can make the secret key rate of the system evaluated precisely. The analysis shows that these countermeasures can effectively resist this potential attack.

关键词： Quantum communication Quantum cryptography Quantum information processing with continuous variables

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The chemical evolution of the solar neighbourhood for planet-hosting stars

arXiv

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arXiv 2023年

作者： Pignatari, Marco Trueman, Thomas C.L. Womack, Kate A. Gibson, Brad K. Côté, Benoit Turrini, Diego Sneden, Christopher Mojzsis, Stephen J. Stancliffe, Richard J. Fong, Paul Lawson, Thomas V. Keegans, James D. Pilkington, Kate Passy, Jean-Claude Beers, Timothy C. Lugaro, Maria ELKH Konkoly Thege M. út 15–17 BudapestH-1121 Hungary CSFK MTA Centre of Excellence Konkoly Thege Miklós út 15-17. BudapestH-1121 Hungary E. A. Milne Centre for Astrophysics Department of Physics and Mathematics University of Hull HU6 7RX United Kingdom INAF - Turin Astrophysical Observatory Via Osservatorio 20 Pino Torinese10025 Italy INAF - Institute of Space Astrophysics and Planetology Via Fosso del Cavaliere 100 Rome00133 Italy ICSC National Research Centre for High Performance Computing Big Data and Quantum Computing Via Magnanelli 2 Casalecchio di Reno40033 Italy Department of Astronomy and McDonald Observatory The University of Texas AustinTX78712 United States NuGrid Collaboration Joint Institute for Nuclear Astrophysics Center for the Evolution of the Elements United States Department of Physics and Astronomy University of Victoria VictoriaBCV8P 5C2 Canada Pázmány Péter sétány 1/c BudapestH-1117 Hungary H.H. Wills Physics Laboratory University of Bristol Tyndall Avenue BristolBS8 1TL United Kingdom Centre of Excellence for Data Science Artificial Intelligence and Modelling University of Hull HU6 7RX United Kingdom Astrophysics Group Lennard-Jones Laboratories Keele University KeeleST5 5BG United Kingdom School of Physical Sciences The Open University Milton KeynesMK7 6AA United Kingdom Max Planck Institute for Intelligent Systems Tübingen Germany Department of Physics and Astronomy University of Notre Dame Notre DameIN46556 United States ELTE Eötvös Loránd University Institute of Physics Pázmány Péter sétány 1/A Budapest1117 Hungary School of Physics and Astronomy Monash University VIC3800 Australia

Theoretical physical-chemical models for the formation of planetary systems depend on data quality for the Sun’s composition, that of stars in the solar neighbourhood, and of the estimated "pristine" compositions for stellar systems. The effective scatter and the observational uncertainties of elements within a few hundred parsecs from the Sun, even for the most abundant metals like carbon, oxygen and silicon, are still controversial. Here we analyse the stellar production and the chemical evolution of key elements that underpin the formation of rocky (C, O, Mg, Si) and gas/ice giant planets (C, N, O, S). We calculate 198 galactic chemical evolution (GCE) models of the solar neighbourhood to analyse the impact of different sets of stellar yields, of the upper mass limit for massive stars contributing to GCE (Mup) and of supernovae from massive-star progenitors which do not eject the bulk of the iron-peak elements (faint supernovae). Even considering the GCE variation produced via different sets of stellar yields, the observed dispersion of elements reported for stars in the Milky Way disk is not reproduced. Among others, the observed range of super-solar [Mg/Si] ratios, sub-solar [S/N], and the dispersion of up to 0.5 dex for [S/Si] challenge our models. The impact of varying Mup depends on the adopted supernova yields. Thus, observations do not provide a constraint on the Mup parametrization. When including the impact of faint supernova models in GCE calculations, elemental ratios vary by up to 0.1-0.2 dex in the Milky Way disk;this modification better reproduces observations. Copyright © 2023, The Authors. All rights reserved.

关键词： Dispersions

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Strategic priorities for transformative progress in advancing biology with proteomics and artificial intelligence

arXiv

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arXiv 2025年

作者： Sun, Yingying Jun, A. Liu, Zhiwei Sun, Rui Qian, Liujia Payne, Samuel H. Bittremieux, Wout Ralser, Markus Li, Chen Chen, Yi Dong, Zhen Perez-Riverol, Yasset Khan, Asif Sander, Chris Aebersold, Ruedi Vizcaíno, Juan Antonio Krieger, Jonathan R. Yao, Jianhua Wen, Han Zhang, Linfeng Zhu, Yunping Xuan, Yue Sun, Benjamin Boyang Qiao, Liang Hermjakob, Henning Tang, Haixu Gao, Huanhuan Deng, Yamin Zhong, Qing Chang, Cheng Bandeira, Nuno Li, Ming Weinan, E. Sun, Siqi Yang, Yuedong Omenn, Gilbert S. Zhang, Yue Xu, Ping Fu, Yan Liu, Xiaowen Overall, Christopher M. Wang, Yu Deutsch, Eric W. Chen, Luonan Cox, Jürgen Demichev, Vadim He, Fuchu Huang, Jiaxing Jin, Huilin Liu, Chao Li, Nan Luan, Zhongzhi Song, Jiangning Yu, Kaicheng Wan, Wanggen Wang, Tai Zhang, Kang Zhang, Le Bell, Peter A. Mann, Matthias Zhang, Bing Guo, Tiannan Affiliated Hangzhou First People’s Hospital State Key Laboratory of Medical Proteomics School of Medicine Westlake University Zhejiang Province Hangzhou China Westlake Center for Intelligent Proteomics Westlake Laboratory of Life Sciences and Biomedicine Zhejiang Province Hangzhou China Biology Department Brigham Young University ProvoUT84602 United States Department of Computer Science University of Antwerp Antwerp2020 Belgium Department of Biochemistry CharitéUniversitätsmedizin Berlin Berlin Germany Biomedicine Discovery Institute Department of Biochemistry and Molecular Biology Monash University MelbourneVICVIC 3800 Australia Wellcome Genome Campus Hinxton CambridgeCB10 1SD United Kingdom Harvard Medical School Ludwig Center at Harvard United States Harvard Medical School Broad Institute Ludwig Center at Harvard Dana-Farber Cancer Institute United States Department of Biology Institute of Molecular Systems Biology ETH Zürich Zürich Switzerland Bruker Ltd. MiltonONL9T 6P4 Canada AI for Life Sciences Lab Tencent Shenzhen518057 China State Key Laboratory of Medical Proteomics AI for Science Institute Beijing100080 China Beijing Institute of Lifeomics Beijing102206 China Thermo Fisher Scientific GmbH Hanna-Kunath Str. 11 Bremen28199 Germany Informatics and Predictive Sciences Research Bristol Myers Squibb United States Department of Chemistry Fudan University Songhu Road 2005 Shanghai200438 China Department of Computer Science Luddy School of Informatics Computing and Engineering Indiana University IN47408 United States ProCan® Children’s Medical Research Institute Faculty of Medicine and Health The University of Sydney WestmeadNSW Australia La Jolla CA United States Central China Institute of Artificial Intelligence University of Waterloo Canada AI for Science Institute Center for Machine Learning Research School of Mathematical Sciences Peking University China Research Institute of Intelligent Complex Systems Fudan U

Artificial intelligence (AI) is transforming scientific research, including proteomics. Advances in mass spectrometry (MS)-based proteomics data quality, diversity, and scale, combined with groundbreaking AI techniques, are unlocking new challenges and opportunities in biological discovery. Here, we highlight key areas where AI is driving innovation, from data analysis to new biological insights. These include developing an AI-friendly ecosystem for proteomics data generation, sharing, and analysis;improving peptide and protein identification and quantification;characterizing protein-protein interactions and protein complexes;advancing spatial and perturbation proteomics;integrating multi-omics data;and ultimately enabling AI-empowered virtual cells. © 2025, CC BY.

关键词： Biotic

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Inexact Block Coordinate Descent Algorithms for Nonsmooth Nonconvex Optimization

arXiv

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arXiv 2019年

作者： Yang, Yang Pesavento, Marius Luo, Zhi-Quan Ottersten, Björn Center for High Performance Computing Fraunhofer Institute for Industrial Mathematics Kaiserslautern67663 Germany Communication Systems Group Technische Universität Darmstadt Darmstadt64283 Germany Shenzhen Research Institute of Big Data Chinese University of Hong Kong Shenzhen China Department of Electrical and Computer Engineering University of Minnesota MinneapolisMN55455 United States University of Luxembourg LuxembourgL-1855 Luxembourg

In this paper, we propose an inexact block coordinate descent algorithm for large-scale nonsmooth nonconvex optimization problems. At each iteration, a particular block variable is selected and updated by solving the original optimization problem with respect to that block variable inexactly. More precisely, a local approximation of the original optimization problem is solved. The proposed algorithm has several attractive features, namely, i) high flexibility, as the approximation function only needs to be strictly convex and it does not have to be a global upper bound of the original function;ii) fast convergence, as the approximation function can be designed to exploit the problem structure at hand and the stepsize is calculated by the line search;iii) low complexity, as the approximation subproblems are much easier to solve and the line search scheme is carried out over a properly constructed differentiable function;iv) guaranteed (subsequence) convergence to a stationary point, even when the objective function does not have a Lipschitz continuous gradient. Interestingly, when the approximation subproblem is solved by a descent algorithm, (subsequence) convergence to a stationary point is still guaranteed even if the approximation subproblem is solved inexactly by terminating the descent algorithm after a finite number of iterations. These features make the proposed algorithm suitable for large-scale problems where the dimension exceeds the memory and/or the processing capability of the existing hardware. These features are also illustrated by several applications in signal processing and machine learning, for instance, network anomaly detection and phase retrieval. Copyright © 2019, The Authors. All rights reserved.

关键词： Big data

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REFUGE2 CHALLENGE: A TREASURE TROVE FOR MULTI-DIMENSION ANALYSIS AND EVALUATION IN GLAUCOMA SCREENING

arXiv

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arXiv 2022年

作者： Fang, Huihui Li, Fei Wu, Junde Fu, Huazhu Sun, Xu Son, Jaemin Yu, Shuang Zhang, Menglu Yuan, Chenglang Bian, Cheng Lei, Baiying Zhao, Benjian Xu, Xinxing Li, Shaohua Fumero, Francisco Sigut, José Almubarak, Haidar Bazi, Yakoub Guo, Yuanhao Zhou, Yating Baid, Ujjwal Innani, Shubham Guo, Tianjiao Yang, Jie Orlando, José Ignacio Bogunović, Hrvoje Zhang, Xiulan Xu, Yanwu The REFUGE2 Challenge Australia State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangzhou China Intelligent Healthcare Unit Baidu Inc. Beijing China The Institute of High Performance Computing Agency for Science Technology and Research Singapore Yatiris Group PLADEMA Institute CONICET UNICEN Tandil Argentina Christian Doppler Lab for Artificial Intelligence in Retina Department of Ophthalmology and Optometry Medical University of Vienna Vienna Austria VUNO Inc Seoul Korea Republic of Tencent HealthCare Tencent Shenzhen China Computer Vision Institute College of Computer Science and Software Engineering of Shenzhen University Shenzhen China School of Biomedical Engineering Health Science Center Shenzhen University China Xiaohe Healthcare ByteDance Guangdong Guangzhou510000 China School of Biomedical Engineering Shenzhen University China College of Computer Science & Software Engineering Shenzhen University China Department of Computer Science and Systems Engineering Universidad de La Laguna Spain Saudi Electronic University Saudi Arabia King Saud University Saudi Arabia Institute of Automation Chinese Academy of Sciences Beijing China University of Chinese Academy of Sciences Beijing China SGGS Institute of Engineering and Technology India Institute of Medical Robotics Shanghai Jiao Tong University China Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University China

With the rapid development of artificial intelligence (AI) in medical image processing, deep learning in color fundus photography (CFP) analysis is also evolving. Although there are some open-source, labeled datasets of CFPs in the ophthalmology community, large-scale datasets for screening only have labels of disease categories, and datasets with annotations of fundus structures are usually small in size. In addition, labeling standards are not uniform across datasets, and there is no clear information on the acquisition device. Here we release a multi-annotation, multi-quality, and multi-device color fundus image dataset for glaucoma analysis on an original challenge-Retinal Fundus Glaucoma Challenge 2nd Edition (REFUGE2). The REFUGE2 dataset contains 2000 color fundus images with annotations of glaucoma classification, optic disc/cup segmentation, as well as fovea localization. Meanwhile, the REFUGE2 challenge sets three sub-tasks of automatic glaucoma diagnosis and fundus structure analysis and provides an online evaluation framework. Based on the characteristics of multi-device and multi-quality data, some methods with strong generalizations are provided in the challenge to make the predictions more robust. This shows that REFUGE2 brings attention to the characteristics of real-world multi-domain data, bridging the gap between scientific research and clinical application. © 2022, CC BY-NC-ND.

关键词： Color

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Strong in-plane anisotropy in the electronic structure of fixed-valence β-lualb4

arXiv

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arXiv 2020年

作者： Reiss, Pascal Baglo, Jordan Tan, Hong'En Chen, Xiaoye Friedemann, Sven Kuga, Kentaro Malte Grosche, F. Nakatsuji, Satoru Sutherland, Michael Cavendish Laboratory University of Cambridge CambridgeCB3 0HE United Kingdom Clarendon Laboratory University of Oxford OxfordOX1 3PU United Kingdom Complex Systems Group Institute of High Performance Computing A*STAR Singapore138632 Singapore HH Wills Laboratory University of Bristol BristolBS8 1TL United Kingdom Institute for Solid State Physics University of Tokyo Kashiwa277-8581 Japan CREST Japan Science and Technology Agency Kawaguchi Saitama332-0012 Japan Department of Physics University of Tokyo Bunkyo-ku Tokyo113-0033 Japan Trans-scale Quantum Science Institute University of Tokyo Bunkyo-ku Tokyo113-0033 Japan

The origin of intrinsic quantum criticality in the heavy-fermion superconductor β-YbAlB4 has been attributed to strong Yb valence fluctuations and to its peculiar crystal structure. Here, we assess these contributions individually by studying the isostructural but fixed-valence compound βLuAlB4. Quantum oscillation measurements and DFT calculations reveal a Fermi surface markedly different from that of β-YbAlB4, consistent with a 'large Fermi surface there. We also find an unexpected in-plane anisotropy of the electronic structure, in contrast to the isotropic Kondo hybrization in β-YbAlB4. Copyright © 2020, The Authors. All rights reserved.

关键词： Fermi surface

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Security analysis of practical continuous-variable quantum key distribution systems under laser seeding attack

arXiv

引用

arXiv 2019年

作者： Zheng, Yi Huang, Peng Huang, Anqi Peng, Jinye Zeng, Guihua College of Information Science and Technology Northwest University Xi’anShaanxi710127 China State Key Laboratory of Advanced Optical Communication Systems and Networks Center of Quantum Information Sensing and Processing Shanghai Jiao Tong University Shanghai200240 China Institute for Quantum Information & State Key Laboratory of High Performance Computing College of Computer National University of Defense Technology Changsha410073 China Greatwall Quantum Laboratory China Greatwall Technology Changsha410205 China

Here, we investigate the security of the practical one-way CVQKD and CV-MDI-QKD systems under laser seeding attack. In particular, Eve can inject a suitable light into the laser diodes of the light source modules in the two kinds of practical CVQKD systems, which results in the increased intensity of the generated optical signal. The parameter estimation under the attack shows that the secret key rates of these two schemes may be overestimated, which opens a security loophole for Eve to successfully perform an intercept-resend attack on these systems. To close this loophole, we propose a real-time monitoring scheme to precisely evaluate the secret key rates of these schemes. The analysis results indicate the implementation of the proposed monitoring scheme can effectively resist this potential attack. Copyright © 2019, The Authors. All rights reserved.

关键词： Light sources

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Practical security of continuous-variable quantum key distribution with reduced optical attenuation

arXiv

引用

arXiv 2019年

In a practical CVQKD system, the optical attenuator can adjust the Gaussian-modulated coherent states and the local oscillator signal to an optimal value for guaranteeing the security of the system and optimizing the performance of the system. However, the performance of the optical attenuator may deteriorate due to the intentional and unintentional damage of the device. In this paper, we investigate the practical security of a CVQKD system with reduced optical attenuation. We find that the secret key rate of the system may be overestimated based on the investigation of parameter estimation under the effects of reduced optical attenuation. This opens a security loophole for Eve to successfully perform an intercept-resend attack in a practical CVQKD system. To close this loophole, we add an optical fuse at Alice’s output port and design a scheme to monitor the level of optical attenuation in real time, which can make the secret key rate of the system evaluated precisely. The analysis shows that these countermeasures can effectively resist this potential attack. Copyright © 2019, The Authors. All rights reserved.

关键词： Electromagnetic wave attenuation

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