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Dielectric Nanocavity Enhanced Fluorescence Emission for Ultrasensitive Wavelength-Multiplexed Detection

Nano Letters 2025年 2025 May 20页

作者： Fu, Bowen Yuan, Zhiyi Fang, Guocheng Wang, Wen-Jie Xiong, Zhongshu Chen, Yu-Cheng School of Electrical and Electronic Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore Institute for Digital Molecular Analytics and Science (IDMxS) Nanyang Technological University 59 Nanyang Drive Singapore 636921 Singapore Key Lab of Advanced Transducers and Intelligent Control System of Ministry of Education Taiyuan University of Technology Taiyuan 030024 China

This study demonstrates a novel biosensing platform utilizing a dielectric nanocavity to enhance fluorescence emission for the ultrasensitive detection of biomolecules. By coupling a silver (Ag) nanocube with a distributed Bragg reflector (DBR) mirror, we achieved a substantial fluorescence enhancement reaching a maximum enhancement factor of up to 855-fold and having quasi-single molecule sensitivity. The platform was successfully applied for multiplexed detection of four different miRNA biomarkers, showcasing its ability to detect multiple targets simultaneously with high sensitivity. The simplicity, rapid speed, and small detection volume (down to 0.5 μL) of this system make it suitable for high-throughput and large-area nanocavity imaging. Our findings offer a promising solution for ultrasensitive, multiplexed biosensing with potential applications in disease diagnosis, personalized medicine, and digital molecular diagnostics. © 2025 American Chemical Society.

关键词： dielectric-coupled nanocavity fluorescence enhancement high-throughput biosensing multiplexed detection nanoparticle quasi-single molecule level detection

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CS/Gel/MWCNTs Conductive Scaffolds Assisted by Electrical Stimulus for Skin Tissue Engineering

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Biotechnology and Bioengineering 2025年 2025 May 15页

作者： Liu, Zixian Ma, Zijun Li, Nini Zhang, Jinyao Li, Meng Han, Lu Cheng, Rong Shen, Zhizhong Han, Dan Sang, Shengbo Shanxi Key Laboratory of Artificial Intelligence & Micro Nano Sensors College of Integrated Circuits Taiyuan University of Technology Shanxi Province Taiyuan China Key Lab of Advanced Transducers and Intelligent Control System of the Ministry of Education Taiyuan University of Technology Shanxi Province Taiyuan China College of chemistry and chemical Engineering North University of china Shanxi Province Taiyuan China Shanxi Research Institute of 6D Artificial Intelligence Biomedical Science Shanxi Province Taiyuan China

Hydrogel scaffolds show high potential in tissue engineering due to excellent mechanical properties and biocompatibility. However, an inherent lack of conductivity limits its application in areas requiring electrical stimulation. To address this issue, chitosan (CS)/gelatin (Gel) scaffolds were prepared with various concentrations of multi-walled carbon nanotubes (MWCNTs). Results indicated that MWCNT incorporation significantly improved both the electrical conductivity and mechanical strength of the scaffolds, with the CS/Gel/0.3% MWCNTs scaffold demonstrating superior biocompatibility compared to other formulations. Additionally, fibroblasts seeded onto the scaffolds responded positively to electrical stimulation, showing increased proliferation and elevated expression of type I and type III collagen. These findings highlight the potential of CS/Gel/MWCNTs scaffolds to enhance wound healing in skin tissue engineering. © 2025 Wiley Periodicals LLC.

关键词： Fiber bonding

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Excavator Energy-saving Efficiency Based on Diesel Engine Cylinder Deactivation Technology

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Chinese Journal of Mechanical Engineering 2012年第5期25卷 897-904页

作者： YANG Jing QUAN Long YANG Yang Key Laboratory of Advanced Transducers and Intelligent Control System of Ministry of Education Taiyuan University of Technology Taiyuan 030024 China The State Key Lab of Fluid Power Transmission and Control Zhejiang University Hangzhou 31002 7 China

The hydraulic excavator energy-saving research mainly embodies the following three measures： to improve the performance of diesel engine and hydraulic component, to improve the hydraulic system, and to improve the power matching of diesel-hydraulic system-actuator. Although the above measures have certain energy-saving effect, but because the hydraulic excavator load changes frequently and fluctuates dramatically, so the diesel engine often works in high-speed and light load condition, and the fuel consumption is higher. Therefore, in order to improve the economy of diesel engine in light load, and reduce the fuel consumption of hydraulic excavator, energy management concept is proposed based on diesel engine cylinder deactivation technology. By comparing the universal characteristic under diesel normal and deactivated cylinder condition, the mechanism that fuel consumption can be reduced significantly by adopting cylinder deactivation technology under part of loads condition can be clarified. The simulation models for hydraulic system and diesel engine are established by using AMESim software, and fuel combustion consumption by using cylinder-deactivation-technology is studied through digital simulation approach. In this way, the zone of cylinder deactivation is specified. The testing system for the excavator with this technology is set up based on simulated results, and the results show that the diesel engine can still work at high efficiency with part of loads after adopting this technology; fuel consumption is dropped down to 11% and 13% under economic and heavy-load mode respectively under the condition of driving requirements. The research provides references to the energy-saving study of the hydraulic excavators.

关键词： diesel engine cylinder deactivation hydraulic excavator energy-saving

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Simulation Study on the controllable Dielectrophoresis Parameters of Graphene

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Chinese Physics Letters 2017年第4期34卷 71-74页

作者： Jian-Long Ji Ya-Li Liu Yang Ge Sheng-Dong Xie Xi Zhang Sheng-Bo Sang Ao-Qun Jian Qian-Qian Duan Qiang Zhang Wen-Dong Zhang Key Lab of Advanced Transducers and Intelligent Control System(Ministry of Education) Taiyuan University of TechnologyTaiyuan 030024 Advanced Coal Mine Machinery and Equipment Collaborative Innovation Center of Shanxi Province Taiyuan University of TechnologyTaiyuan 030024

The method of using dielectrophoresis （DEP） to assemble graphene between micro-electrodes has been proven to be simple and efficient. We present an optimization method for the kinetic formula of graphene DEP, and discuss the simulation of the graphene assembly process based on the finite element method. The simulated results illustrate that the accelerated motion of graphene is in agreement with the distribution of the electric field squared gradient. We also conduct research on the controllable parameters of the DEP assembly such as the alternating current （AC） frequency, the shape of micro-electrodes, and the ratio of the gap between electrodes to the characteristic/geometric length of graphene （λ）. The simulations based on the Clausius-Mossotti factor reveal that both graphene velocity and direction are influenced by the AC frequency. When graphene is close to the electrodes, the shape of micro-electrodes will exert great influence on the velocity of graphene. Also, λ has a great influence on the velocity of graphene. Generally, the velocity of graphene would be greater when λ is in the range of 0.4 0.6. The study is of a theoretical guiding significance in improving the precision and efficiency of the graphene DEP assembly.

关键词： DEP Simulation Study on the controllable Dielectrophoresis Parameters of Graphene

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An Efficiency Enhanced Graphene/n-Si Schottky Junction for Solar Cells

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Chinese Physics Letters 2018年第7期35卷 58-61页

作者：李刚程宏伟郭丽芳王开鹰程再军 MicroNano System Research Center College of Information and Computer & Key Lab of Advanced Transducers and Intelligent Control System of Ministry of Education Taiyuan University of Technology Taiyuan 030024 School of Optoelectronic and Communication Engineering Xiamen University of Technology Xiamen 361024

A novel and facile oxidation-induced self-doping process of graphene-silicon Schottky junction by nitric acid（HNO3） vapor is reported. The HNO3 oxidation process makes graphene p-type self-doped, and leads to a higher built-in potential and conductivity to enhance charge transfer and to suppress charge carrier recombination at the graphene-silicon Schottky junction. After the HNO3 oxidation process, the open-circuit voltage is increased from the initial value of 0.36 V to the maximum value of 0.47 V, the short-circuit current is greatly increased from 0.80μA to 7.71μA, and the ideality factor is optimized from 4.4 to 1.0. The enhancement of the performance of graphene-Si solar cells may be due to oxidation-induced p-type self-doping of graphene-Si junctions.

关键词： Graphene

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controllable optical bistability in a three-mode optomechanical system with a membrane resonator

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Chinese Physics B 2018年第7期27卷 382-387页

作者： Jiakai Yan Xiaofei Zhu Bin Chen Department of Physics College of Physics and OptoelectronicsTaiyuan University of TechnologyTaiyuan 030024Chin Key Lab of Advanced Transducers and Intelligent Control System Ministry of Education and Shanxi ProvinceTaiyuan 030024China

We study the optical bistability （OB） in a three-mode cavity optomechanical system, where an oscillating membrane of perfect reflection is inserted between two fixed mirrors of partial transmission. By investigating the behavior of steady state solutions, we find that the left and right cavities will exhibit the bistable behavior simultaneously in this optomechanical system by adjusting the left and right coupling fields. In addition, one can control the OB threshold and the width of the OB curve via adjusting the coupling strength, the detuning, and the decay rate. Moreover, we further illustrate the OB appearing in the cavity by the effective potential as a function of the position.

关键词： optical bistability oscillating membrane optomechanical system

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Robustness margin in linear time invariant fractional order systems

Robustness margin in linear time invariant fractional order ...

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4th IFAC Symposium on system, Structure and control, SSSC 2010

作者： Moornani, Kamran Akbari Haeri, Mohammad Electrical Engineering Department Advanced Control System Lab Sharif University of Technology Tehran Iran

ISBN: (纸本)9783902661838

In this paper, the computation of robustness margin for linear time invariant fractional order systems is studied. For the definition of robustness margin, we employ the one introduced for polynomials (i.e. integer order) and extend it to fractional order functions. Using the well known concept of the value set and knowing its shape for the intended functions, this paper presents an easy way to obtain the robustness margin for fractional order systems. To illustrate the results, a numerical example is provided. © 2010 IFAC.

关键词： Linear systems

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A receding horizon control of a cooperative multi target tracking system

A receding horizon control of a cooperative multi target tra...

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2011 2nd International Conference on Instrumentation control and Automation, ICA 2011

作者： Pari, Ehsan Moradi Haeri, Mohammad Electrical Engineering Department Sharif University of Technology Advanced Control System Lab Tehran Iran

ISBN: (纸本)9781457714603

In this paper the problem of cooperative tracking of multiple targets for multi-agent systems is investigated. Defining problem of target tracking as gathering maximum rewards associated with the targets, an optimization-based algorithm is presented. A cooperative receding horizon controller for reaching moving targets is proposed. Agents are controlled by adjusting their headings toward the moving targets. A notable advantage of the proposed approach is the estimations of target's motion and planning the agent's heading based on them. Simulation results are provided to verify the efficiency of the proposed method. © 2011 IEEE.

关键词： Target tracking

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Bearing Fault Diagnosis with DDCNN Based on Intelligent Feature Fusion Strategy in Strong Noise

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Computers, Materials & Continua 2023年第12期77卷 3423-3442页

作者： Chaoqian He Runfang Hao Kun Yang Zhongyun Yuan Shengbo Sang Xiaorui Wang College of Electronic Information and Optical Engineering Taiyuan University of TechnologyTaiyuan030024China Key Lab of Advanced Transducers and Intelligent Control System of the Ministry of Education Taiyuan030024China

Intelligent fault diagnosis in modern mechanical equipment maintenance is increasingly adopting deep learning ***,conventional bearing fault diagnosis models often suffer from low accuracy and unstable performance in noisy environments due to their reliance on a single input ***,this paper proposes a dual-channel convolutional neural network(DDCNN)model that leverages dual data *** DDCNN model introduces two key ***,one of the channels substitutes its convolution with a larger kernel,simplifying the structure while addressing the lack of global information and shallow ***,the feature layer combines data from different sensors based on their primary and secondary importance,extracting details through small kernel convolution for primary data and obtaining global information through large kernel convolution for secondary *** experiments conducted on two-bearing fault datasets demonstrate the superiority of the two-channel convolution model,exhibiting high accuracy and robustness even in strong noise ***,it achieved an impressive 98.84%accuracy at a Signal to Noise Ratio(SNR)of−4 dB,outperforming other advanced convolutional models.

关键词： Fault diagnosis dual-data dual-channel feature fusion noise-resistance

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Synchronizing two different fractional order hyperchaotic systems using generalized fractional order sliding mode control

Synchronizing two different fractional order hyperchaotic sy...

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2011 2nd International Conference on Instrumentation control and Automation, ICA 2011

作者： Abooee, Ali Haeri, Mohammad Electrical Engineering Department Sharif University of Technology Advanced Control System Lab Tehran Iran

ISBN: (纸本)9781457714603

Synchronization of two fractional order hyperchaotic systems considering uncertainties and sector nonlinear inputs is investigated in this paper. A new fractional order sliding mode control scheme is proposed to synchronize two different fractional order hyperchaotic systems in the presence of uncertainties, sector nonlinearity in the control inputs. The stability of the error dynamics is proven using Lyapunov stability theorem. Simulation results are provided to verify the feasibility and effectiveness of the proposed synchronizing method. © 2011 IEEE.

关键词： Sliding mode control

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