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Physical Review E 2019年第1期99卷 010201(R)-010201(R)页

作者： Nan Yao Zi-Gang Huang Hai-Peng Ren Celso Grebogi Ying-Cheng Lai Department of Applied Physics Xi'an University of Technology Xi'an 710048 China The Key Laboratory of Biomedical Information Engineering of Ministry of Education National Engineering Research Center of Health Care and Medical Devices The Key Laboratory of Neuro-informatics & Rehabilitation Engineering of Ministry of Civil Affairs and Institute of Health and Rehabilitation Science School of Life Science and Technology Xi'an Jiaotong University Xi'an 710049 China Shaanxi Key Laboratory of Complex System Control and Intelligent Information Processing Xi'an University of Technology Xi'an 710048 China Institute for Complex Systems and Mathematical Biology King's College University of Aberdeen Aberdeen AB24 3UE United Kingdom School of Electrical Computer and Energy Engineering Arizona State University Tempe Arizona 85287 USA Department of Physics Arizona State University Tempe Arizona 85287 USA

Chimera states in spatiotemporal dynamical systems have been investigated in physical, chemical, and biological systems, and have been shown to be robust against random perturbations. How do chimera states achieve their robustness? We uncover a self-adaptation behavior by which, upon a spatially localized perturbation, the coherent component of the chimera state spontaneously drifts to an optimal location as far away from the perturbation as possible, exposing only its incoherent component to the perturbation to minimize the disturbance. A systematic numerical analysis of the evolution of the spatiotemporal pattern of the chimera state towards the optimal stable state reveals an exponential relaxation process independent of the spatial location of the perturbation, implying that its effects can be modeled as restoring and damping forces in a mechanical system and enabling the articulation of a phenomenological model. Not only is the model able to reproduce the numerical results, it can also predict the trajectory of drifting. Our finding is striking as it reveals that, inherently, chimera states possess a kind of “intelligence” in achieving robustness through self-adaptation. The behavior can be exploited for the controlled generation of chimera states with their coherent component placed in any desired spatial region of the system.

关键词： Chimera states Collective dynamics Coupled oscillators Chaos & nonlinear dynamics

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Perturbed Tumor Immunotherapy Domain of Attraction Estimation via the Arc-Length Function

Perturbed Tumor Immunotherapy Domain of Attraction Estimatio...

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Iranian Conference of Biomedical Engineering (ICBME)

作者： Mojtaba Zarei Kimia Javadi Ahmad Kalhor Cyber-Physical Systems Lab (CPSL) Departments of Electrical and Computer Engineering Duke University NC USA Faculty of Computer and Electrical Engineering K.N.Toosi University of Technology Tehran Iran Control and Intelligent Processing Center of Excellence School of Electrical and Computer Engineering University of Tehran Tehran Iran

ISBN: (纸本)9781538679531;9781538679524

This paper aims at the estimation of the Domain of Attraction (DoA) of the free tumor equilibrium point of perturbed tumor immunotherapy model via the Arc-Length Function (ALF). The ALFs are categorized among the maximal Lyapunov functions which are able to provide a more accurate estimation of the DoA in comparison to their other counterparts such as Rational Lyapunov Functions (RLFs), Sum Of Square (SOS) polynomial Lyapunov functions, and Optimal Quadratic Lyapunov Functions (OQLFs). There is no analytical method to construct the ALFs, however, some numerical methods have been proposed in the literature. Based on the existing method, one can approximate the ALF with a certain degree of a polynomial function. That the system under study has a polynomial structure was the main basis of the previously proposed method to estimate the DoA via the ALFs. However, the intended model in this paper describing the tumor-immune system competition dynamics contains non-polynomial terms. To cope with the aforementioned problem, the Taylor expansion of the non-polynomial terms are considered and by solving an optimization problem, one can calculate the corresponding lower boundary of the level set with the approximated ALF as an estimation of the DoA. In order to represent the performance of the employed method, the obtained result is compared with the reported result in the literature.

关键词： Tumors Direction-of-arrival estimation Lyapunov methods Estimation Immune system Mathematical model Cancer

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Author Correction: Frontotemporal coordination predicts working memory performance and its local neural signatures

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Nature communications 2021年第1期12卷 3811页

作者： Ehsan Rezayat Mohammad-Reza A Dehaqani Kelsey Clark Zahra Bahmani Tirin Moore Behrad Noudoost School of Cognitive Sciences Institute for Research in Fundamental Sciences (IPM) Tehran Iran. School of Cognitive Sciences Institute for Research in Fundamental Sciences (IPM) Tehran Iran. dehaqani@ut.ac.ir. Cognitive Systems Laboratory Control and Intelligent Processing Center of Excellence (CIPCE) School of Electrical and Computer Engineering College of Engineering University of Tehran Tehran Iran. dehaqani@ut.ac.ir. Department of Ophthalmology and Visual Sciences University of Utah Salt Lake City UT USA. Department of Biomedical Engineering Tarbiat Modares University Tehran Iran. Department of Neurobiology Stanford University Stanford CA USA. Howard Hughes Medical Institute Stanford University Stanford CA USA. Department of Ophthalmology and Visual Sciences University of Utah Salt Lake City UT USA. behrad.noudoost@utah.edu.

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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

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Nature 2024年第8003期627卷 347-357页

作者： Ken Suzuki Konstantinos Hatzikotoulas Lorraine Southam Henry J Taylor Xianyong Yin Kim M Lorenz Ravi Mandla Alicia Huerta-Chagoya Giorgio E M Melloni Stavroula Kanoni Nigel W Rayner Ozvan Bocher Ana Luiza Arruda Kyuto Sonehara Shinichi Namba Simon S K Lee Michael H Preuss Lauren E Petty Philip Schroeder Brett Vanderwerff Mart Kals Fiona Bragg Kuang Lin Xiuqing Guo Weihua Zhang Jie Yao Young Jin Kim Mariaelisa Graff Fumihiko Takeuchi Jana Nano Amel Lamri Masahiro Nakatochi Sanghoon Moon Robert A Scott James P Cook Jung-Jin Lee Ian Pan Daniel Taliun Esteban J Parra Jin-Fang Chai Lawrence F Bielak Yasuharu Tabara Yang Hai Gudmar Thorleifsson Niels Grarup Tamar Sofer Matthias Wuttke Chloé Sarnowski Christian Gieger Darryl Nousome Stella Trompet Soo-Heon Kwak Jirong Long Meng Sun Lin Tong Wei-Min Chen Suraj S Nongmaithem Raymond Noordam Victor J Y Lim Claudia H T Tam Yoonjung Yoonie Joo Chien-Hsiun Chen Laura M Raffield Bram Peter Prins Aude Nicolas Lisa R Yanek Guanjie Chen Jennifer A Brody Edmond Kabagambe Ping An Anny H Xiang Hyeok Sun Choi Brian E Cade Jingyi Tan K Alaine Broadaway Alice Williamson Zoha Kamali Jinrui Cui Manonanthini Thangam Linda S Adair Adebowale Adeyemo Carlos A Aguilar-Salinas Tarunveer S Ahluwalia Sonia S Anand Alain Bertoni Jette Bork-Jensen Ivan Brandslund Thomas A Buchanan Charles F Burant Adam S Butterworth Mickaël Canouil Juliana C N Chan Li-Ching Chang Miao-Li Chee Ji Chen Shyh-Huei Chen Yuan-Tsong Chen Zhengming Chen Lee-Ming Chuang Mary Cushman John Danesh Swapan K Das H Janaka de Silva George Dedoussis Latchezar Dimitrov Ayo P Doumatey Shufa Du Qing Duan Kai-Uwe Eckardt Leslie S Emery Daniel S Evans Michele K Evans Krista Fischer James S Floyd Ian Ford Oscar H Franco Timothy M Frayling Barry I Freedman Pauline Genter Hertzel C Gerstein Vilmantas Giedraitis Clicerio González-Villalpando Maria Elena González-Villalpando Penny Gordon-Larsen Myron Gross Lindsay A Guare Sophie Hackinger Liisa Hakaste Sohee Han Andrew T Hattersley Christian Herder Momoko Horikoshi Annie-Green Howard Willa Centre for Genetics and Genomics Versus Arthritis Centre for Musculoskeletal Research Division of Musculoskeletal and Dermatological Sciences University of Manchester Manchester UK. Department of Diabetes and Metabolic Diseases Graduate School of Medicine University of Tokyo Tokyo Japan. Department of Statistical Genetics Osaka University Graduate School of Medicine Suita Japan. Institute of Translational Genomics Helmholtz Zentrum München German Research Center for Environmental Health Neuherberg Germany. konstantinos.hatzikotoulas@helmholtz-munich.de. Institute of Translational Genomics Helmholtz Zentrum München German Research Center for Environmental Health Neuherberg Germany. Center for Precision Health Research National Human Genome Research Institute National Institutes of Health Bethesda MD USA. British Heart Foundation Cardiovascular Epidemiology Unit Department of Public Health and Primary Care University of Cambridge Cambridge UK. Heart and Lung Research Institute University of Cambridge Cambridge UK. Department of Epidemiology School of Public Health Nanjing Medical University Nanjing China. Department of Biostatistics and Center for Statistical Genetics University of Michigan Ann Arbor MI USA. Corporal Michael J. Crescenz VA Medical Center Philadelphia PA USA. Department of Systems Pharmacology and Translational Therapeutics University of Pennsylvania Perelman School of Medicine Philadelphia PA USA. Department of Genetics University of Pennsylvania Perelman School of Medicine Philadelphia PA USA. Programs in Metabolism and Medical and Population Genetics Broad Institute of Harvard and MIT Cambridge MA USA. Diabetes Unit and Center for Genomic Medicine Massachusetts General Hospital Boston MA USA. TIMI Study Group Division of Cardiovascular Medicine Brigham and Women's Hospital Harvard Medical School Boston MA USA. William Harvey Research Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London L

Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms that are often specific to cell type. Here, to characterize the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study data from 2,535,601 individuals (39.7% not of European ancestry), including 428,452 cases of T2D. We identify 1,289 independent association signals at genome-wide significance (P < 5 × 10) that map to 611 loci, of which 145 loci are, to our knowledge, previously unreported. We define eight non-overlapping clusters of T2D signals that are characterized by distinct profiles of cardiometabolic trait associations. These clusters are differentially enriched for cell-type-specific regions of open chromatin, including pancreatic islets, adipocytes, endothelial cells and enteroendocrine cells. We build cluster-specific partitioned polygenic scores in a further 279,552 individuals of diverse ancestry, including 30,288 cases of T2D, and test their association with T2D-related vascular outcomes. Cluster-specific partitioned polygenic scores are associated with coronary artery disease, peripheral artery disease and end-stage diabetic nephropathy across ancestry groups, highlighting the importance of obesity-related processes in the development of vascular outcomes. Our findings show the value of integrating multi-ancestry genome-wide association study data with single-cell epigenomics to disentangle the aetiological heterogeneity that drives the development and progression of T2D. This might offer a route to optimize global access to genetically informed diabetes care.

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Optimal tracking cooperative control for multi-agent systems with periodic sampling via robust model predictive control approach 36

Optimal tracking cooperative control for multi-agent systems...

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第36届中国控制会议

作者： Bohui Wang Weisheng Chen Jingcheng Wang Bin Zhang Zhengqiang Zhang Hai Lin Bin Ma the School of Aerospace Science and Technology Xidian University the Department of Automation Shanghai Jiao Tong Universityand Key Laboratory of System Control and Information ProcessingMinistry of Education of China the Autonomous Systems and Intelligent Control international Joint Research Center Xian Technological University the Department of Electrical Engineering University of South Carolina the with the School of Engineering Qufu Normal University

ISBN: (纸本)9781538629185

This paper addresses the optimized tracking cooperative control problem for multi-agent systems with periodic sampling and directed communication topology via robust model predictive control *** proposed optimized tracking cooperative control strategy relaxes the assumptions in existing works that the control gain and the local input must be continuous and the states information exchange has no recourse *** the conditions of the optimized consensus and the communication cost being satisfied,the tracking cooperative control law with bounded parameters is developed based on the periodic *** shows that if the sampling condition is satisfied,the multi-agent systems will reach the optimized *** results are provided to verify the proposed approach.

关键词： Index Terms-multi-agent systems tracking cooperative control periodic sampling optimized consensus robust model predictive control

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Hybrid quantum-classical convolutional neural networks

arXiv

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arXiv 2019年

作者： Liu, Junhua Lim, Kwan Hui Wood, Kristin L. Huang, Wei Guo, Chu Huang, He-Liang Information Systems Technology and Design Singapore University of Technology and Design 8 Somapah Road 487372 Singapore SUTD-MIT International Design Center Singapore University of Technology and Design 8 Somapah Road 487372 Singapore Engineering Product Develoment Singapore University of Technology and Design 8 Somapah Road 487372 Singapore Guangxi Key Laboratory of Optoelectronic Information Processing Guilin University of Electronic Technology Guilin541004 China Key Laboratory of Low-Dimensional Quantum Structures and Quantum Control of Ministry of Education Department of Physics Synergetic Innovation Center for Quantum Effects and Applications Hunan Normal University Changsha410081 China Hefei National Laboratory for Physical Sciences at Microscale Department of Modern Physics University of Science and Technology of China Anhui Hefei230026 China Shanghai Branch Cas Ctr. for Excellence and Synergetic Innovation Centre in Quantum Information and Quantum Physics University of Science and Technology of China Anhui Hefei201315 China Henan Key Laboratory of Quantum Information and Cryptography Henan Zhengzhou450000 China

Deep learning has been shown to be able to recognize data patterns better than humans in specific circumstances or contexts. In parallel, quantum computing has demonstrated to be able to output complex wave functions with a few number of gate operations, which could generate distributions that are hard for a classical computer to produce. Here we propose a hybrid quantum-classical convolutional neural network (QCCNN), inspired by convolutional neural networks (CNNs) but adapted to quantum computing to enhance the feature mapping process. QCCNN is friendly to currently noisy intermediate-scale quantum computers, in terms of both number of qubits as well as circuit's depths, while retaining important features of classical CNN, such as nonlinearity and scalability. We also present a framework to automatically compute the gradients of hybrid quantum-classical loss functions which could be directly applied to other hybrid quantum-classical algorithms. We demonstrate the potential of this architecture by applying it to a Tetris dataset, and show that QCCNN can accomplish classification tasks with learning accuracy surpassing that of classical CNN. Copyright © 2019, The Authors. All rights reserved.

关键词： Convolution

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Weak value amplification via second-order correlated technique

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Chinese Physics B 2016年第2期25卷 58-61页

作者：崔挺黄靖正刘翔曾贵华 State Key Laboratory of Advanced Optical Communication Systems and Networks Shanghai Key Laboratory on Navigation and Location-based Serviceand Center of Quantum Information Sensing and Processing Shanghai Jiao Tong University Shanghai Key Laboratory of Aerospace Intelligent Control Technology Shanghai Institute of Spaceflight Control Technology College of Information Science and Technology Northwest University

We propose a new framework combining weak measurement and second-order correlated technique. The theoretical analysis shows that weak value amplification （WVA） experiment can also be implemented by a second-order correlated system. We then build two-dimensional second-order correlated function patterns for achieving higher amplification factor and discuss the signal-to-noise ratio influence. Several advantages can be obtained by our proposal. For instance, detectors with high resolution are not necessary. Moreover, detectors with low saturation intensity are available in WVA setup. Finally, type-one technical noise can be effectively suppressed.

关键词： weak measurement two-dimensional second-order correlated function

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Spike-burst chimera states in an adaptive exponential integrate-and-fire neuronal network

arXiv

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arXiv 2019年

作者： Santos, Moises S. Protachevicz, Paulo R. Iarosz, Kelly C. Caldas, Iberê L. Viana, Ricardo L. Borges, Fernando S. Ren, Hai-Peng Szezech, José D. Batista, Antonio M. Grebogi, Celso Department of Physics Federal University of Paraná CuritibaPR80060-000 Brazil Graduate in Science Program - Physics State University of Ponta Grossa Ponta Grossa PR84030-900 Brazil Institute of Physics University of São Paulo São PauloSP05508-900 Brazil Center for Mathematics Computation and Cognition Federal University of ABC São Bernardo do CampoSP09606-045 Brazil Shaanxi Key Laboratory of Complex System Control and Intelligent Information Processing Xian University of Technology Xi'an710048 China Xian Technological University Xi'an710021 China Graduate in Science Program - Physics State University of Ponta Grossa Ponta Grossa PR84030-900 Brazil Institute for Complex Systems and Mathematical Biology King's College University of Aberdeen AberdeenAB24 3UE United Kingdom

Chimera states are spatiotemporal patterns in which coherence and incoherence coexist. We observe the coexistence of synchronous (coherent) and desynchronous (incoherent) domains in a neuronal network. The network is composed of coupled adaptive exponential integrate-and-fire neurons that are connected by means of chemical synapses. In our neuronal network, the chimera states exhibit spatial structures both with spikes and bursts activities. Furthermore, those desynchronised domains not only have either spike or burst activity, but we show that the structures switch between spikes and bursts as the time evolves. Moreover, we verify the existence of multicluster chimera states. Copyright © 2019, The Authors. All rights reserved.

关键词： Neural networks

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Incremental learning of high-level concepts by imitation

arXiv

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arXiv 2017年

作者： Alibeigi, Mina Ahmadabadi, Majid Nili Araabi, Babak Nadjar Cognitive Systems Lab School of Electrical and Computer Engineering College of Engineering University of Tehran Tehran Iran Cognitive Systems Lab. Control and Intelligent Processing Center of Excellence School of Electrical and Computer Engineering College of Engineering University of Tehran Tehran Iran Tehran Iran

Nowadays, robots become a companion in everyday life. To be well-accepted by humans, robots should efficiently understand meanings of their partners’ motions and body language, and respond accordingly. Learning concepts by imitation brings them this ability in a user-friendly way. This paper presents a fast and robust model for Incremental Learning of Concepts by Imitation (ILoCI). In ILoCI, observed multimodal spatio-temporal demonstrations are incrementally abstracted and generalized based on both their perceptual and functional similarities during the imitation. In this method, perceptually similar demonstrations are abstracted by a dynamic model of mirror neuron system. An incremental method is proposed to learn their functional similarities through a limited number of interactions with the teacher. Learning all concepts together by the proposed memory rehearsal enables robot to utilize the common structural relations among concepts which not only expedites the learning process especially at the initial stages, but also improves the generalization ability and the robustness against discrepancies between observed demonstrations. Performance of ILoCI is assessed using standard LASA handwriting benchmark data set. The results show efficiency of ILoCI in concept acquisition, recognition and generation in addition to its robustness against variability in demonstrations. Copyright © 2017, The Authors. All rights reserved.

关键词： Abstracting

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Machine discovery of partial differential equations from spatiotemporal data

arXiv

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arXiv 2019年

作者： Yuan, Ye Li, Junlin Li, Liang Jiang, Frank Tang, Xiuchuan Zhang, Fumin Liu, Sheng Goncalves, Jorge Voss, Henning U. Li, Xiuting Kurths, Jürgen Ding, Han School of Artificial Intelligence and Automation State Key Laboratory of Digital Manufacturing Equipments and Technology Huazhong University of Science and Technology Wuhan430074 China School of Artificial Intelligence and Automation Key Laboratory of Image Processing and Intelligent Control Huazhong University of Science and Technology Wuhan430074 China School of Electrical Engineering and Computer Science KTH Royal Institute of Technology Stockholm11428 Sweden School of Mechanical Science and Engineering Huazhong University of Science and Technology Wuhan430074 China School of Electrical and Computer Engineering Georgia Institute of Technology Atlanta30332 United States School of Power and Mechanical Engineering Wuhan University Wuhan430074 China Department of Engineering University of Cambridge CambridgeCB2 1PZ United Kingdom Luxembourg Centre for Systems Biomedicine University of Luxembourg BelvauxL-4367 Luxembourg Citigroup Biomedical Imaging Center Weill Cornell Medical College New York10021 United States Research Domain IV - Transdisciplinary Concepts & Methods Potsdam Institute for Climate Impact Research Potsdam14473 Germany School of Mechanical Science and Engineering State Key Laboratory of Digital Manufacturing Equipments and Technology Huazhong University of Science and Technology Wuhan430074 China

The study presents a general framework for discovering underlying Partial Differential Equations (PDEs) using measured spatiotemporal data. The method, called Sparse Spatiotemporal System Discovery (S3d), decides which physical terms are necessary and which can be removed (because they are physically negligible in the sense that they do not affect the dynamics too much) from a pool of candidate functions. The method is built on the recent development of Sparse Bayesian Learning;which enforces the sparsity in the to-be-identified PDEs, and therefore can balance the model complexity and fitting error with theoretical guarantees. Without leveraging prior knowledge or assumptions in the discovery process, we use an automated approach to discover ten types of PDEs, including the famous Navier-Stokes and sine-Gordon equations, from simulation data alone. Moreover, we demonstrate our data-driven discovery process with the Complex Ginzburg-Landau Equation (CGLE) using data measured from a traveling-wave convection experiment. Our machine discovery approach presents solutions that has the potential to inspire, support and assist physicists for the establishment of physical laws from measured spatiotemporal data, especially in notorious fields that are often too complex to allow a straightforward establishment of physical law, such as biophysics, fluid dynamics, neuroscience or nonlinear optics. Copyright © 2019, The Authors. All rights reserved.

关键词： Nonlinear optics

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