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arXiv 2024年

作者： Xing, Xiaodan Tang, Chunling Murdoch, Siofra Papanastasiou, Giorgos Guo, Yunzhe Xiao, Xianglu Cross-Zamirski, Jan Schönlieb, Carola-Bibiane Liang, Kristina Xiao Niu, Zhangming Fang, Evandro Fei Wang, Yinhai Yang, Guang Bioengineering Department and Imperial-X Imperial College London London United Kingdom Centre for Craniofacial & Regenerative Biology King’s College London London United Kingdom Archimedes Unit Athena Research Centre Athens Greece School of Computer Science and Electronic Engineering The University of Essex Essex United Kingdom Department of Applied Mathematics and Theoretical Physics University of Cambridge Cambridge United Kingdom University of Bergen Bergen Norway MindRank AI Ltd. Hangzhou China Department of Clinical Molecular Biology University of Oslo Akershus University Hospital Lørenskog Norway Data Sciences and Quantitative Biology Discovery Sciences AstraZeneca R&D Cambridge United Kingdom National Heart and Lung Institute Imperial College London London United Kingdom School of Biomedical Engineering & Imaging Sciences King’s College London London United Kingdom Cardiovascular Research Centre Royal Brompton Hospital London United Kingdom

Immunofluorescent (IF) imaging is crucial for visualizing biomarker expressions, cell morphology and assessing the effects of drug treatments on sub-cellular components. IF imaging needs extra staining process and often requiring cell fixation, therefore it may also introduce artefects and alter endogenouous cell morphology. Some IF stains are expensive or not readily available hence hindering experiments. Recent diffusion models, which synthesise high-fidelity IF images from easy-to-acquire brightfield (BF) images, offer a promising solution but are hindered by training instability and slow inference times due to the noise diffusion process. This paper presents a novel method for the conditional synthesis of IF images directly from BF images along with cell segmentation masks. Our approach employs a Residual Diffusion process that enhances stability and significantly reduces inference time. We performed a critical evaluation against other image-to-image synthesis models, including UNets, GANs, and advanced diffusion models. Our model demonstrates significant improvements in image quality (p © 2024, CC BY-SA.

关键词： Image segmentation

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Redefining pandemic preparedness:Multidisciplinary insights from the CERP modelling workshop in infectious diseases,workshop report

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Infectious Disease Modelling 2024年第2期9卷 501-518页

作者： Marta C.Nunes Edward Thommes Holger Fröhlich Antoine Flahault Julien Arino Marc Baguelin Matthew Biggerstaff Gaston Bizel-Bizellot Rebecca Borchering Giacomo Cacciapaglia Simon Cauchemez Alex Barbier-Chebbah Carsten Claussen Christine Choirat Monica Cojocaru Catherine Commaille-Chapus Chitin Hon Jude Kong Nicolas Lambert Katharina B.Lauer Thorsten Lehr Cédric Mahe Vincent Marechal Adel Mebarki Seyed Moghadas Rene Niehus Lulla Opatowski Francesco Parino Gery Pruvost Andreas Schuppert Rodolphe Thiébaut Andrea Thomas-Bachli Cecile Viboud Jianhong Wu Pascal Crépey Laurent Coudeville Center of Excellence in Respiratory Pathogens(CERP) Hospices Civils de Lyon(HCL)and Centre International de Recherche en Infectiologie(CIRI)Équipe SantéPubliqueÉpidémiologie etÉcologieÉvolutive des Maladies Infectieuses(PHE3ID)Inserm U1111CNRS UMR5308ENS de LyonUniversitéClaude Bernard Lyon 1LyonFrance South African Medical Research Council Vaccines&Infectious Diseases Analytics Research UnitFaculty of Health SciencesUniversity of the WitwatersrandJohannesburgSouth Africa New Products and Innovation(NPI) Sanofi Vaccines(Global)TorontoOntarioCanada Department of Mathematics and Statistics University of GuelphGuelphOntarioCanada Fraunhofer Institute for Algorithms and Scientific Computing(SCAI) Department of BioinformaticsSchloss BirlinghovenSankt AugustinGermany University of Bonn Bonn-Aachen International Center for IT(b-it)BonnGermany Institute of Global Health Faculty of MedicineUniversity of GenevaGenevaSwitzerland and Swiss School of Public HealthZürichSwitzerland Department of Mathematics University of ManitobaWinnipegManitobaCanada MRC Centre for Global Infectious Disease Analysis School of Public HealthImperial College LondonLondonUK Centre for Mathematical Modelling of Infectious Diseases Department of Infectious Disease EpidemiologyLondon School of Hygiene&Tropical MedicineLondonUK National Center for Immunization and Respiratory Diseases(NCIRD) US Centers for Disease Control and Prevention(CDC)AtlantaGAUSA Departement of Computational Biology Departement of Global HealthInstitut PasteurParisFrance Institut de Physique des Deux Infinis de Lyon(IP2I) UMR5822IN2P3/CNRSUniversitéClaude Bernard Lyon 1VilleurbanneFrance Mathematical Modelling of Infectious Diseases Unit Institut PasteurUniversitéParis CitéUMR2000 CNRSParisFrance Decision and Bayesian Computation Institut PasteurUniversitéParis CitéCNRS UMR 3571France Fraunhofer-Institute for Translational Medicine and Pharmacology HamburgGermany Institute of Global Health Faculty of MedicineUniversity of

In July 2023,the Center of Excellence in Respiratory Pathogens organized a two-day workshop on infectious diseases modelling and the lessons learnt from the Covid-19 *** report summarizes the rich discussions that occurred during the *** workshop participants discussed multisource data integration and highlighted the benefits of combining traditional surveillance with more novel data sources like mobility data,social media,and wastewater *** advancements were noted in the development of predictive models,with examples from various countries showcasing the use of machine learning and artificial intelligence in detecting and monitoring disease *** role of open collaboration between various stakeholders in modelling was stressed,advocating for the continuation of such partnerships beyond the pandemic.A major gap identified was the absence of a common international framework for data sharing,which is crucial for global pandemic ***,the workshop underscored the need for robust,adaptable modelling frameworks and the integration of different data sources and collaboration across sectors,as key elements in enhancing future pandemic response and preparedness.

关键词： Modelling Covid-19 Infectious diseases Pandemic preparedness Workshop

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RL Perceptron: Generalization Dynamics of Policy Learning in High Dimensions

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Physical Review X 2025年第2期15卷 021051-021051页

作者： Nishil Patel Sebastian Lee Stefano Sarao Mannelli Sebastian Goldt Andrew Saxe Gatsby Computational Neuroscience Unit University College London Gower Street London WC1E 6BT United Kingdom Imperial College London Exhibition Road South Kensington London SW7 2AZ United Kingdom Data Science and AI Computer Science and Engineering Chalmers University of Technology and University of Gothenburg Gothenburg Sweden School of Computer Science and Applied Mathematics University of the Witwatersrand Johannesburg South Africa International School of Advanced Studies (SISSA) Via Bonomea 265 34136 Trieste Italy Sainsbury Wellcome Centre University College London 25 Howland Street London W1T 4JG United Kingdom

Reinforcement learning (RL) algorithms have transformed many domains of machine learning. To tackle real-world problems, RL often relies on neural networks to learn policies directly from pixels or other high-dimensional sensory input. By contrast, many theories of RL have focused on discrete state spaces or worst-case analysis, and fundamental questions remain about the dynamics of policy learning in high-dimensional settings. Here, we propose a solvable high-dimensional RL model that can capture a variety of learning protocols, and we derive its typical policy learning dynamics as a set of closed-form ordinary differential equations. We obtain optimal schedules for the learning rates and task difficulty—analogous to annealing schemes and curricula during training in RL—and show that the model exhibits rich behavior, including delayed learning under sparse rewards, a variety of learning regimes depending on reward baselines, and a speed-accuracy trade-off driven by reward stringency. Experiments on variants of the Procgen game “Bossfight” and Arcade Learning Environment game “Pong” also show such a speed-accuracy trade-off in practice. Together, these results take a step toward closing the gap between theory and practice in high-dimensional RL.

关键词： Differential equations

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P18.04.B SINGLE CELL TRANSCRIPTOMIC ANALYSIS IDENTIFIES DISTINCT INTRATUMORAL SUBCLONES IN MENINGIOMA

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Neuro-Oncology 2023年第SUPPLEMENT_2期25卷 ii122–ii122页

作者： Blume, C Tang, Y Dogan, H Ritter, M Dentro, S von Deimling, A Gerstung, M Schlesner, M Sahm, F Maas, S L N University Hospital Heidelberg Dept. of Neuropathology Heidelberg Germany German Cancer Research Center (DKFZ) German Consortium for Translational Cancer Research (DKTK) Clinical Cooperation Unit Neuropathology Heidelberg Germany Division of AI in Oncology German Cancer Research Center (DKFZ) Heidelberg Germany European Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI) Hinxton United Kingdom Biomedical Informatics Data Mining and Data Analytics Faculty of Applied Computer Science and Medical Faculty University of Augsburg Augsburg Germany Department of Pathology Leiden University Medical Center Leiden Netherlands Department of Pathology Erasmus Medical Center Rotterdam Netherlands

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Why is the Winner the Best?

Why is the Winner the Best?

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Conference on Computer Vision and Pattern Recognition (CVPR)

作者： M. Eisenmann A. Reinke V. Weru M. D. Tizabi F. Isensee T. J. Adler S. Ali V. Andrearczyk M. Aubreville U. Baid S. Bakas N. Balu S. Bano J. Bernal S. Bodenstedt A. Casella V. Cheplygina M. Daum M. De Bruijne A. Depeursinge R. Dorent J. Egger D. G. Ellis S. Engelhardt M. Ganz N. Ghatwary G. Girard P. Godau A. Gupta L. Hansen K. Harada M. Heinrich N. Heller A. Hering A. Huaulmé P. Jannin A. E. Kavur O. Kodym M. Kozubek J. Li H. Li J. Ma C. Martín-Isla B. Menze A. Noble V. Oreiller N. Padoy S. Pati K. Payette T. Rädsch J. Rafael-Patiño V. Singh Bawa S. Speidel C. H. Sudre K. Van Wijnen M. Wagner D. Wei A. Yamlahi M. H. Yap C. Yuan M. Zenk A. Zia D. Zimmerer D. Aydogan B. Bhattarai L. Bloch R. Brüngel J. Cho C. Choi Q. Dou I. Ezhov C. M. Friedrich C. Fuller R. R. Gaire A. Galdran Á. García Faura M. Grammatikopoulou S. Hong M. Jahanifar I. Jang A. Kadkhodamohammadi I. Kang F. Kofler S. Kondo H. Kuijf M. Li M. Luu T. Martinčič P. Morais M. A. Naser B. Oliveira D. Owen S. Pang J. Park S. Park S. Płotka E. Puybareau N. Rajpoot K. Ryu N. Saeed A. Shephard P. Shi D. Štepec R. Subedi G. Tochon H. R. Torres H. Urien J. L. Vilaça K. A. Wahid H. Wang J. Wang L. Wang X. Wang B. Wiestler M. Wodzinski F. Xia J. Xie Z. Xiong S. Yang Y. Yang Z. Zhao K. Maier-Hein P. F. Jäger A. Kopp-Schneider L. Maier-Hein Division of Intelligent Medical Systems German Cancer Research Center (DKFZ) Heidelberg Germany Helmholtz Imaging German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Division of Biostatistics German Cancer Research Center (DKFZ) Heidelberg Germany Division of Medical Image Computing German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Engineering and Physical Sciences School of Computing University of Leeds Leeds UK Institute of Informatics School of Management HES-SO Valais-Wallis University of Applied Sciences and Arts Western Switzerland Sierre Switzerland Department of Nuclear Medicine and Molecular Imaging Lausanne University Hospital Lausanne Switzerland Technische Hochschule Ingolstadt Ingolstadt Germany Center for Artificial Intelligence and Data Science for Integrated Diagnostics (AI2D) and Center for Biomedical Image Computing and Analytics (CBICA) University of Pennsylvania Philadelphia PA USA Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Radiology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Radiology University of Washington Seattle WA USA Department of Computer Science Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS) University College London London UK Universitat Autònoma de Barcelona & Computer Vision Center Barcelona Spain Division of Translational Surgical Oncology National Center for Tumor Diseases (NCT/UCC) Dresden Dresden Germany Department of Advanced Robotics Istituto Italiano di Tecnologia Italy Department of Electronics Information and Bioengineering Politecnico di Milano Milan Italy IT University of Copenhagen Copenhagen Denmark Department of General Visceral and Transplantation Surgery Heidelberg University Hospital Heidelberg Germany Department of Radiology and Nuc

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do they really generate scientific progress? What are common and successful participation strategies? What makes a solution superior to a competing method? To address this gap in the literature, we performed a multicenter study with all 80 competitions that were conducted in the scope of IEEE ISBI 2021 and MICCai 2021. Statistical analyses performed based on comprehensive descriptions of the submitted algorithms linked to their rank as well as the underlying participation strategies revealed common characteristics of winning solutions. These typically include the use of multi-task learning (63%) and/or multi-stage pipelines (61%), and a focus on augmentation (100%), image preprocessing (97%), data curation (79%), and post-processing (66%). The “typical” lead of a winning team is a computer scientist with a doctoral degree, five years of experience in biomedical image analysis, and four years of experience in deep learning. Two core general development strategies stood out for highly-ranked teams: the reflection of the metrics in the method design and the focus on analyzing and handling failure cases. According to the organizers, 43% of the winning algorithms exceeded the state of the art but only 11% completely solved the respective domain problem. The insights of our study could help researchers (1) improve algorithm development strategies when approaching new problems, and (2) focus on open research questions revealed by this work.

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Explainable ai: Definition and attributes of a good explanation for health ai

arXiv

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arXiv 2024年

作者： Kyrimi, Evangelia McLachlan, Scott Wohlgemut, Jared M. Perkins, Zane B. Lagnado, David A. Marsh, William Gimson, Alexander Shafti, Ali Ercole, Ari Banerjee, Amitava Glocker, Ben Schafer, Burkhard Gatsonis, Constantine Grosan, Crina Sent, Danielle Berman, David S. Glass, David O'Regan, Declan P. Letsios, Dimitrios Morrissey, Dylan Pisirir, Erhan Leofante, Francesco Soyel, Hamit Williamson, Jon Grieman, Keri Dube, Kudakwashe Mardsen, Max Nagendran, Myura Tai, Nigel Kostopoulou, Olga Jones, Owain Curzon, Paul Stoner, Rebecca S. Tandle, Sankalp Joshi, Shalmali Mossadegh, Somayyeh Buijsman, Stefan Miller, Tim Madai, Vince Istvan School of Electronic Engineering and Computer Science Queen Mary University of London London United Kingdom School of Nursing Midwifery and Palliative Care King's College London London United Kingdom Centre for Trauma Sciences Blizard Institute Queen Mary University of London London United Kingdom Royal London Hospital Barts Health NHS Trust London United Kingdom Department of Experiment Psychology University College London London United Kingdom Cambridge Liver Unit Addenbrooke's Hospital Cambridge University Hospitals Hills Road Box 210 Cambridge United Kingdom University of Cambridge United Kingdom Cambridge Consultants Ltd. United Kingdom Division of Anaesthesia Cambridge Centre for AI in Medicine University of Cambridge Cambridge United Kingdom Magdelene College University of Cambridge United Kingdom Institute of Health Informatics University College London London United Kingdom Department of Computing Imperial College London London United Kingdom SCRIPT Centre for IT and IP Law School of Law University of Edinburgh United Kingdom Center for Statistical Sciences School of Public Health Brown University Providence United States Research Group Artificial Intelligence HU University of Applied Sciences Utrecht Netherlands Jheronimus Academy of Data Science Tilburg University Eindhoven University of Technology s-Hertogenbosch Netherlands Centre for Theoretical Physics Queen Mary University of London London United Kingdom School of Computing Ulster University Belfast United Kingdom MRC Laboratory of Medical Sciences Imperial College London London United Kingdom Department of Informatics King's College London United Kingdom Physiotherapy Department Barts Health NHS Trust London United Kingdom Sport and Exercise Medicine Queen Mary University of London London United Kingdom School of Electronic Engineering and Computer Science Queen Mary University of London United Kingdom Department of Computing Imperial College London United Kingdom Departmen

Proposals of artificial intelligence (ai) solutions based on increasingly complex and accurate predictive models are becoming ubiquitous across many disciplines. As the complexity of these models grows, transparency and users' understanding often diminish. This suggests that accurate prediction alone is insufficient for making an ai-based solution truly useful. In the development of healthcare systems, this introduces new issues related to accountability and safety. Understanding how and why an ai system makes a recommendation may require complex explanations of its inner workings and reasoning processes. Although research on explainable ai (Xai) has significantly increased in recent years and there is high demand for Xai in medicine, defining what constitutes a good explanation remains ad hoc, and providing adequate explanations continues to be challenging. To fully realize the potential of ai, it is critical to address two fundamental questions about explanations for safety-critical ai applications, such as health-ai: (1) What is an explanation in health-ai? and (2) What are the attributes of a good explanation in health-ai? In this study, we examined published literature and gathered expert opinions through a two-round Delphi study. The research outputs include (1) a definition of what constitutes an explanation in health-ai and (2) a comprehensive list of attributes that characterize a good explanation in health-ai. © 2024, CC BY.

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Computational Approaches to Explainable Artificial Intelligence: Advances Intheory, Applications and Trends

SSRN

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SSRN 2023年

作者： Górriz, Juan Manuel Álvarez-Illán, I. Álvarez-Marquina, A. Arco, J.E. Atzmueller, M. Ballarini, F. Barakova, E. Bologna, G. Bonomini, P. Castellanos-Dominguez, G. Castillo-Barnes, D. Cho, S.B. Contreras, R. Cuadra, J.M. Domínguez, E. Domínguez-Mateos, F. Duro, R.J. Elizondo, D. Fernández-Caballero, A. Fernandez-Jover, E. Formoso, M.A. Gallego-Molina, N.J. Gamazo, J. García González, J. Garcia-Rodriguez, J. Garre, C. Garrigós, J. Gómez-Rodellar, A. Gómez-Vilda, P. Graña, M. Guerrero-Rodriguez, B. Hendrikse, S.C.F. Jimenez-Mesa, C. Jodra-Chuan, M. Julian, V. Kotz, G. Kutt, K. Leming, M. de Lope, J. Macas, B. Marrero-Aguiar, V. Martinez, J.J. Martinez-Murcia, F.J. Martínez-Tomás, R. Mekyska, J. Nalepa, G.J. Novais, P. Orellana, D. Ortiz, A. Palacios-Alonso, D. Palma, J. Pereira, A. Pinacho-Davidson, P. Pinninghoff, M.A. Ponticorvo, M. Psarrou, A. Ramírez, J. Rincón, M. Rodellar-Biarge, V. Rodríguez-Rodríguez, I. Roelofsma, P.H.M.P. Santos, J. Salas-Gonzalez, D. Salcedo-Lagos, P. Segovia, F. Shoeibi, A. Silva, M. Simic, D. Suckling, J. Treur, J. Tsanas, A. Varela, R. Wang, S.H. Wang, W. Zhang, Y.D. Zhu, H. Zhu, Z. Ferrández-Vicente, J.M. SiPBA at Data Science and Computational Intelligence Institute University of Granada Granada Spain University of Granada Granada Spain Dept. of Psychiatry University of Cambridge Cambridge United Kingdom Dept. of Communications Engineering University of Malaga Malaga Spain School of Computing and Mathematical Sciences University of Leicester Leicester United Kingdom Semantic Information Systems Group Osnabrück University Osnabrück Germany Osnabrück Germany Dept. of Electronics Computer Technology and Projects Universidad Politécnica de Cartagena Cartagena Spain Universitat Politècnica de València València Spain Institute of Applied Computer Science Jagiellonian University Kraków Poland Dept. of Information and Communication Engineering University of Murcia Murcia Spain Dept. of Computer Science and Information Technologies University of A Coruña A Coruña Spain Dept. of Computer Science University of Oviedo Oviedo Spain Buenos Aires Argentina Buenos Aires Argentina Eindhoven University of Technology Eindhoven5612 AZ Netherlands Dept. of Computer Science University of Malaga Malaga Spain De Montfort University Leicester United Kingdom Dept. of Computer Science Faculty of Engineering Universidad de Concepción Concepción Chile Neurocognition and Emotion Research Unit Albacete Research Institute of Informatics University of Castilla-La Mancha Albacete Spain Dept. of Educational Informatics Universidad de Concepción Concepción Chile Madrid Spain Dept. of Humanistic Studies University of Naples Federico II Napoli Italy Escuela Técnica Superior de Ingeniería Informática Universidad Rey Juan Carlos Campus de Móstoles Móstoles Madrid28933 Spain Neuromorphic Speech Processing Lab Center for Biomedical Technology Universidad Politécnica de Madrid Campus de Montegancedo Pozuelo de Alarcón Madrid28223 Spain Biomedical Research Networking Center in Mental Health Instituto de Salud Carlos III Madrid28016 Spain Usher Institute Faculty o

Groundbreaking advances in theoretical and applied Artificial Intelligence (ai). DL algorithms are groundedin non-linear and complex artificial neural systems that progressively extract higher-level features from *** is frequently compared with human-level performance in real-world tasks, such as clinical diagnostics. Itis also a turning point in solving otherwise intractable problems in the design of virtual agents or robotics;orin providing novel insight into disease progress in genomics and Neuroimaging (NI), understanding humanbrain function, the automation of industrial processes based on computer vision, and so on. In this paper, themost relevant advances from the last few years in ai and several applications to neuroscience, neuroimaging,computer vision, and robotics are presented, reviewed and discussed. In this way, we summarize the state-ofthe-art in ai methods, models and applications within a collection of works presented at the 9th InternationalConference on the Interplay between Natural and Artificial Computation (IWINAC). The works presentedin this paper are excellent examples of new scientific discoveries made in laboratories that are successfullytransferred to real-life applications. © 2023, The Authors. All rights reserved.

关键词： Neuroimaging

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SPT clusters with DES and HST weak lensing. I. Cluster lensing and Bayesian population modeling of multiwavelength cluster datasets

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Physical Review D 2024年第8期110卷 083509页

作者： S. Bocquet S. Grandis L. E. Bleem M. Klein J. J. Mohr M. Aguena A. Alarcon S. Allam S. W. Allen O. Alves A. Amon B. Ansarinejad D. Bacon M. Bayliss K. Bechtol M. R. Becker B. A. Benson G. M. Bernstein M. Brodwin D. Brooks A. Campos R. E. A. Canning J. E. Carlstrom A. Carnero Rosell M. Carrasco Kind J. Carretero R. Cawthon C. Chang R. Chen A. Choi J. Cordero M. Costanzi L. N. da Costa M. E. S. Pereira C. Davis J. DeRose S. Desai T. de Haan J. De Vicente H. T. Diehl S. Dodelson P. Doel C. Doux A. Drlica-Wagner K. Eckert J. Elvin-Poole S. Everett I. Ferrero A. Ferté A. M. Flores J. Frieman J. García-Bellido M. Gatti G. Giannini M. D. Gladders D. Gruen R. A. Gruendl I. Harrison W. G. Hartley K. Herner S. R. Hinton D. L. Hollowood W. L. Holzapfel K. Honscheid N. Huang E. M. Huff D. J. James M. Jarvis G. Khullar K. Kim R. Kraft K. Kuehn N. Kuropatkin F. Kéruzoré S. Lee P.-F. Leget N. MacCrann G. Mahler A. Mantz J. L. Marshall J. McCullough M. McDonald J. Mena-Fernández R. Miquel J. Myles A. Navarro-Alsina R. L. C. Ogando A. Palmese S. Pandey A. Pieres A. A. Plazas Malagón J. Prat M. Raveri C. L. Reichardt J. Roberson R. P. Rollins A. K. Romer C. Romero A. Roodman A. J. Ross E. S. Rykoff L. Salvati C. Sánchez E. Sanchez D. Sanchez Cid A. Saro T. Schrabback M. Schubnell L. F. Secco I. Sevilla-Noarbe K. Sharon E. Sheldon T. Shin M. Smith T. Somboonpanyakul B. Stalder A. A. Stark V. Strazzullo E. Suchyta M. E. C. Swanson G. Tarle C. To M. A. Troxel I. Tutusaus T. N. Varga A. von der Linden N. Weaverdyck J. Weller P. Wiseman B. Yanny B. Yin M. Young Y. Zhang J. Zuntz University Observatory Faculty of Physics Universität Innsbruck Institut für Astro- und Teilchenphysik Technikerstr. 25/8 6020 Innsbruck Austria Argonne National Laboratory 9700 South Cass Avenue Lemont Illinois 60439 USA Kavli Institute for Cosmological Physics University of Chicago Chicago Illinois 60637 USA Max Planck Institute for Extraterrestrial Physics Gießenbachstr. 1 85748 Garching Germany Laboratório Interinstitucional de e-Astronomia - LIneA Rua Gal. José Cristino 77 Rio de Janeiro RJ-20921-400 Brazil Fermi National Accelerator Laboratory P. O. Box 500 Batavia Illinois 60510 USA Kavli Institute for Particle Astrophysics and Cosmology Stanford University 452 Lomita Mall Stanford California 94305 USA Department of Physics Stanford University 382 Via Pueblo Mall Stanford California 94305 USA SLAC National Accelerator Laboratory 2575 Sand Hill Road Menlo Park California 94025 USA Department of Physics University of Michigan Ann Arbor Michigan 48109 USA Institute of Astronomy University of Cambridge Madingley Road Cambridge CB3 0HA United Kingdom Kavli Institute for Cosmology University of Cambridge Madingley Road Cambridge CB3 0HA United Kingdom School of Physics University of Melbourne Parkville Victoria 3010 Australia Institute of Cosmology and Gravitation University of Portsmouth Portsmouth PO1 3FX United Kingdom Department of Physics University of Cincinnati Cincinnati Ohio 45221 USA Physics Department 2320 Chamberlin Hall University of Wisconsin-Madison 1150 University Avenue Madison Wisconsin 53706-1390 USA Department of Astronomy and Astrophysics University of Chicago Chicago Illinois 60637 USA Fermi National Accelerator Laboratory Batavia Illinois 60510-0500 USA Department of Physics and Astronomy University of Pennsylvania Philadelphia Pennsylvania 19104 USA Department of Physics and Astronomy University of Missouri 5110 Rockhill Road Kansas City Missouri 64110 USA Department of Physics and Astronomy University Coll

We present a Bayesian population modeling method to analyze the abundance of galaxy clusters identified by the South Pole Telescope (SPT) with a simultaneous mass calibration using weak gravitational lensing data from the Dark Energy Survey (DES) and the Hubble Space Telescope (HST). We discuss and validate the modeling choices with a particular focus on a robust, weak-lensing-based mass calibration using DES data. For the DES Year 3 data, we report a systematic uncertainty in weak-lensing mass calibration that increases from 1% at z=0.25 to 10% at z=0.95, to which we add 2% in quadrature to account for uncertainties in the impact of baryonic effects. We implement an analysis pipeline that joins the cluster abundance likelihood with a multiobservable likelihood for the Sunyaev-Zel’dovich effect, optical richness, and weak-lensing measurements for each individual cluster. We validate that our analysis pipeline can recover unbiased cosmological constraints by analyzing mocks that closely resemble the cluster sample extracted from the SPT-SZ, SPTpol ECS, and SPTpol 500d surveys and the DES Year 3 and HST-39 weak-lensing datasets. This work represents a crucial prerequisite for the subsequent cosmological analysis of the real dataset.

关键词： Cosmological parameters Gravitational lenses Large scale structure of the Universe

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SPT clusters with DES and HST weak lensing. II. Cosmological constraints from the abundance of massive halos

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Physical Review D 2024年第8期110卷 083510页

作者： S. Bocquet S. Grandis L. E. Bleem M. Klein J. J. Mohr T. Schrabback T. M. C. Abbott P. A. R. Ade M. Aguena A. Alarcon S. Allam S. W. Allen O. Alves A. Amon A. J. Anderson J. Annis B. Ansarinejad J. E. Austermann S. Avila D. Bacon M. Bayliss J. A. Beall K. Bechtol M. R. Becker A. N. Bender B. A. Benson G. M. Bernstein S. Bhargava F. Bianchini M. Brodwin D. Brooks L. Bryant A. Campos R. E. A. Canning J. E. Carlstrom A. Carnero Rosell M. Carrasco Kind J. Carretero F. J. Castander R. Cawthon C. L. Chang C. Chang P. Chaubal R. Chen H. C. Chiang A. Choi T-L. Chou R. Citron C. Corbett Moran J. Cordero M. Costanzi T. M. Crawford A. T. Crites L. N. da Costa M. E. S. Pereira C. Davis T. M. Davis J. DeRose S. Desai T. de Haan H. T. Diehl M. A. Dobbs S. Dodelson C. Doux A. Drlica-Wagner K. Eckert J. Elvin-Poole S. Everett W. Everett I. Ferrero A. Ferté A. M. Flores J. Frieman J. Gallicchio J. García-Bellido M. Gatti E. M. George G. Giannini M. D. Gladders D. Gruen R. A. Gruendl N. Gupta G. Gutierrez N. W. Halverson I. Harrison W. G. Hartley K. Herner S. R. Hinton G. P. Holder D. L. Hollowood W. L. Holzapfel K. Honscheid J. D. Hrubes N. Huang J. Hubmayr E. M. Huff D. Huterer K. D. Irwin D. J. James M. Jarvis G. Khullar K. Kim L. Knox R. Kraft E. Krause K. Kuehn N. Kuropatkin F. Kéruzoré O. Lahav A. T. Lee P.-F. Leget D. Li H. Lin A. Lowitz N. MacCrann G. Mahler A. Mantz J. L. Marshall J. McCullough M. McDonald J. J. McMahon J. Mena-Fernández F. Menanteau S. S. Meyer R. Miquel J. Montgomery J. Myles T. Natoli A. Navarro-Alsina J. P. Nibarger G. I. Noble V. Novosad R. L. C. Ogando Y. Omori S. Padin S. Pandey P. Paschos S. Patil A. Pieres A. A. Plazas Malagón A. Porredon J. Prat C. Pryke M. Raveri C. L. Reichardt J. Roberson R. P. Rollins C. Romero A. Roodman J. E. Ruhl E. S. Rykoff B. R. Saliwanchik L. Salvati C. Sánchez E. Sanchez D. Sanchez Cid A. Saro K. K. Schaffer L. F. Secco I. Sevilla-Noarbe K. Sharon E. Sheldon T. Shin C. Sievers G. Smecher M. Smith T. Somboonpanyakul M. Sommer B. Stalder A. A. Stark J. Stephen V. Straz University Observatory Faculty of Physics Universität Innsbruck Institut für Astro- und Teilchenphysik Technikerstraße 25/8 6020 Innsbruck Austria High-Energy Physics Division Argonne National Laboratory 9700 South Cass Avenue Lemont Illinois 60439 USA Kavli Institute for Cosmological Physics University of Chicago 5640 South Ellis Avenue Chicago Illinois 60637 USA Max Planck Institute for Extraterrestrial Physics Gießenbachstraße 1 85748 Garching Germany Argelander-Institut für Astronomie Auf dem Hügel 71 53121 Bonn Germany Cerro Tololo Inter-American Observatory NSF’s National Optical-Infrared Astronomy Research Laboratory Casilla 603 La Serena Chile School of Physics and Astronomy Cardiff University Cardiff CF24 3YB United Kingdom Laboratório Interinstitucional de e-Astronomia—LIneA Rua Gal. José Cristino 77 Rio de Janeiro Rio de Janeiro—20921-400 Brazil Fermi National Accelerator Laboratory P. O. Box 500 Batavia Illinois 60510 USA Kavli Institute for Particle Astrophysics and Cosmology Stanford University 452 Lomita Mall Stanford California 94305 USA Department of Physics Stanford University 382 Via Pueblo Mall Stanford California 94305 USA SLAC National Accelerator Laboratory 2575 Sand Hill Road Menlo Park California 94025 USA Department of Physics University of Michigan Ann Arbor Michigan 48109 USA Institute of Astronomy University of Cambridge Madingley Road Cambridge CB3 0HA United Kingdom Kavli Institute for Cosmology University of Cambridge Madingley Road Cambridge CB3 0HA United Kingdom School of Physics University of Melbourne Parkville Victoria 3010 Australia NIST Quantum Devices Group 325 Broadway Mailcode 817.03 Boulder Colorado 80305 USA Department of Physics University of Colorado Boulder Colorado 80309 USA Institut de Física d’Altes Energies (IFAE) The Barcelona Institute of Science and Technology Campus UAB 08193 Bellaterra (Barcelona) Spain Institute of Cosmology and Gravitation University of Portsmouth Portsmouth

We present cosmological constraints from the abundance of galaxy clusters selected via the thermal Sunyaev-Zel’dovich (SZ) effect in South Pole Telescope (SPT) data with a simultaneous mass calibration using weak gravitational lensing data from the Dark Energy Survey (DES) and the Hubble Space Telescope (HST). The cluster sample is constructed from the combined SPT-SZ, SPTpol ECS, and SPTpol 500d surveys, and comprises 1,005 confirmed clusters in the redshift range 0.25–1.78 over a total sky area of 5200 deg2. We use DES Year 3 weak-lensing data for 688 clusters with redshifts z<0.95 and HST weak-lensing data for 39 clusters with 0.6ain the SZ observable-mass relation without having to make strong assumptions about, e.g., the hydrodynamical state of the clusters. For a flat ΛCDM cosmology, and marginalizing over the sum of massive neutrinos, we measure Ωm=0.286±0.032, σ8=0.817±0.026, and the parameter combination σ8(Ωm/0.3)0.25=0.805±0.016. Our measurement of S8≡σ8Ωm/0.3=0.795±0.029 and the constraint from Planck CMB anisotropies (2018 TT, TE, EE+lowE) differ by 1.1σ. In combination with that Planck dataset, we place a 95% upper limit on the sum of neutrino masses ∑mν<0.18 eV. When additionally allowing the dark energy equation of state parameter w to vary, we obtain w=−1.45±0.31 from our cluster-based analysis. In combination with Planck data, we measure w=−1.34−0.15+0.22, or a 2.2σ difference with a cosmological constant. We use the cluster abundance to measure σ8 in five redshift bins between 0.25 and 1.8, and we find the results to be consistent with structure growth as predicted by the ΛCDM model fit to Planck primary CMB data.

关键词： Cosmological parameters Dark energy Large scale structure of the Universe Galaxy clusters

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Dark Energy Survey Year 3 results: Constraints on extensions to ΛCDM with weak lensing and galaxy clustering

引用

Physical Review D 2023年第8期107卷 083504-083504页

作者： T. M. C. Abbott M. Aguena A. Alarcon O. Alves A. Amon F. Andrade-Oliveira J. Annis S. Avila D. Bacon E. Baxter K. Bechtol M. R. Becker G. M. Bernstein S. Birrer J. Blazek S. Bocquet A. Brandao-Souza S. L. Bridle D. Brooks D. L. Burke H. Camacho A. Campos A. Carnero Rosell M. Carrasco Kind J. Carretero F. J. Castander R. Cawthon C. Chang A. Chen R. Chen A. Choi C. Conselice J. Cordero M. Costanzi M. Crocce L. N. da Costa M. E. S. Pereira C. Davis T. M. Davis J. DeRose S. Desai E. Di Valentino H. T. Diehl S. Dodelson P. Doel C. Doux A. Drlica-Wagner K. Eckert T. F. Eifler F. Elsner J. Elvin-Poole S. Everett X. Fang A. Farahi I. Ferrero A. Ferté B. Flaugher P. Fosalba D. Friedel O. Friedrich J. Frieman J. García-Bellido M. Gatti L. Giani T. Giannantonio G. Giannini D. Gruen R. A. Gruendl J. Gschwend G. Gutierrez N. Hamaus I. Harrison W. G. Hartley K. Herner S. R. Hinton D. L. Hollowood K. Honscheid H. Huang E. M. Huff D. Huterer B. Jain D. J. James M. Jarvis N. Jeffrey T. Jeltema A. Kovacs E. Krause K. Kuehn N. Kuropatkin O. Lahav S. Lee P.-F. Leget P. Lemos C. D. Leonard A. R. Liddle M. Lima H. Lin N. MacCrann J. L. Marshall J. McCullough J. Mena-Fernández F. Menanteau R. Miquel V. Miranda J. J. Mohr J. Muir J. Myles S. Nadathur A. Navarro-Alsina R. C. Nichol R. L. C. Ogando Y. Omori A. Palmese S. Pandey Y. Park M. Paterno F. Paz-Chinchón W. J. Percival A. Pieres A. A. Plazas Malagón A. Porredon J. Prat M. Raveri M. Rodriguez-Monroy P. Rogozenski R. P. Rollins A. K. Romer A. Roodman R. Rosenfeld A. J. Ross E. S. Rykoff S. Samuroff C. Sánchez E. Sanchez J. Sanchez D. Sanchez Cid V. Scarpine D. Scolnic L. F. Secco I. Sevilla-Noarbe E. Sheldon T. Shin M. Smith M. Soares-Santos E. Suchyta M. Tabbutt G. Tarle D. Thomas C. To A. Troja M. A. Troxel I. Tutusaus T. N. Varga M. Vincenzi A. R. Walker N. Weaverdyck R. H. Wechsler J. Weller B. Yanny B. Yin Y. Zhang J. Zuntz Cerro Tololo Inter-American Observatory NSF’s National Optical-Infrared Astronomy Research Laboratory Casilla 603 La Serena Chile Laboratório Interinstitucional de e-Astronomia-LIneA Rua General José Cristino 77 Rio de Janeiro Rio de Janeiro 20921-400 Brazil Argonne National Laboratory 9700 South Cass Avenue Lemont Illinois 60439 USA Department of Physics University of Michigan Ann Arbor Michigan 48109 USA Institute of Astronomy University of Cambridge Madingley Road Cambridge CB3 0HA United Kingdom Kavli Institute for Cosmology University of Cambridge Madingley Road Cambridge CB3 0HA United Kingdom Fermi National Accelerator Laboratory P. O. Box 500 Batavia Illinois 60510 USA Instituto de Fisica Teorica UAM/CSIC Universidad Autonoma de Madrid 28049 Madrid Spain Institute of Cosmology and Gravitation University of Portsmouth Portsmouth PO1 3FX United Kingdom Institute for Astronomy University of Hawai’i 2680 Woodlawn Drive Honolulu Hawaii 96822 USA Physics Department 2320 Chamberlin Hall University of Wisconsin-Madison 1150 University Avenue Madison Wisconsin 53706-1390 USA Department of Physics and Astronomy University of Pennsylvania Philadelphia Pennsylvania 19104 USA Kavli Institute for Particle Astrophysics and Cosmology P. O. Box 2450 Stanford University Stanford California 94305 USA SLAC National Accelerator Laboratory Menlo Park California 94025 USA Department of Physics Northeastern University Boston Massachusetts 02115 USA University Observatory Faculty of Physics Ludwig-Maximilians-Universität Scheinerstrasse 1 81679 Munich Germany Instituto de Física Gleb Wataghin Universidade Estadual de Campinas 13083-859 Campinas São Paulo Brazil Jodrell Bank Center for Astrophysics School of Physics and Astronomy University of Manchester Oxford Road Manchester M13 9PL United Kingdom Department of Physics and Astronomy University College London Gower Street London WC1E 6BT United Kingdom Instituto de Física Teórica Universidade Estadual

We constrain six possible extensions to the Λ cold dark matter (CDM) model using measurements from the Dark Energy Survey’s first three years of observations, alone and in combination with external cosmological probes. The DES data are the two-point correlation functions of weak gravitational lensing, galaxy clustering, and their cross-correlation. We use simulated data vectors and blind analyses of real data to validate the robustness of our results to astrophysical and modeling systematic errors. In many cases, constraining power is limited by the absence of theoretical predictions beyond the linear regime that are reliable at our required precision. The ΛCDM extensions are dark energy with a time-dependent equation of state, nonzero spatial curvature, additional relativistic degrees of freedom, sterile neutrinos with eV-scale mass, modifications of gravitational physics, and a binned σ8(z) model which serves as a phenomenological probe of structure growth. For the time-varying dark energy equation of state evaluated at the pivot redshift we find (wp,wa)=(−0.99−0.17+0.28,−0.9±1.2) at 68% confidence with zp=0.24 from the DES measurements alone, and (wp,wa)=(−1.03−0.03+0.04,−0.4−0.3+0.4) with zp=0.21 for the combination of all data considered. Curvature constraints of Ωk=0.0009±0.0017 and effective relativistic species Neff=3.10−0.16+0.15 are dominated by external data, though adding DES information to external low-redshift probes tightens the Ωk constraints that can be made without cosmic microwave background observables by 20%. For massive sterile neutrinos, DES combined with external data improves the upper bound on the mass meff by a factor of 3 compared to previous analyses, giving 95% limits of (ΔNeff,meff)≤(0.28,0.20 eV) when using priors matching a comparable Planck analysis. For modified gravity, we constrain changes to the lensing and Poisson equations controlled by functions Σ(k,z)=Σ0ΩΛ(z)/ΩΛ,0 and μ(k,z)=μ0ΩΛ(z)/ΩΛ,0, respectively, to Σ0=0.6−0.5+0.4 fro

关键词： Cosmological constant Cosmological parameters Cosmology Dark energy Dark matter Galaxies Large scale structure of the Universe Telescopes

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