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arXiv 2021年

作者： Nguyen, Huy Tuan Tuan, Nguyen Anh Yang, Chao Department of Mathematics and Computer Science University of Science Ho Chi Minh City Viet Nam Vietnam National University Ho Chi Minh City Viet Nam Division of Applied Mathematics Thu Dau Mot University Binh Duong Province Viet Nam College of Mathematical Sciences Harbin Engineering University 150001 China

This article is a comparative study on an initial-boundary value problem for a class of semilinear pseudo-parabolic equations with the fractional Caputo derivative, also called the fractional Sobolev-Galpern type equations. The purpose of this work is to reveal the influence of the degree of the source nonlinearity on the well-posedness of the solution. By considering four different types of nonlinearities, we derive the global well-posedness of mild solutions to the problem corresponding to the four cases of the nonlinear source terms. For the advection source function case, we apply a nontrivial limit technique for singular integral and some appropriate choices of weighted Banach space to prove the global existence result. For the gradient nonlinearity as a local Lipschitzian, we use the Cauchy sequence technique to show that the solution either exists globally in time or blows up at finite time. For the polynomial form nonlinearity, by assuming the smallness of the initial data we derive the global well-posed results. And for the case of exponential nonlinearity in two-dimensional space, we derive the global well-posedness by additionally use of Orlicz *** Codes 35K20, 35K58 © 2021, CC BY.

关键词： Banach spaces

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Esophageal microbiome correlates with post-esophagectomy anastomotic leak in cancer patients

ESMO Gastrointestinal Oncology

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ESMO Gastrointestinal Oncology 2025年 8卷 100172-100172页

作者： R. Naddaf H. Shmilovich S. Carasso R. Keshet-David R. Herren T. Gefen T. Goshen-Lago Y. Zwang I. Livyatan N. Shental O. Haberfeld R. Straussman S.R. Markar M. Nilsson H. Kashtan I. Ben-Aharon N. Geva-Zatorsky Rappaport Faculty of Medicine Technion Haifa Israel Division of Surgery Rabin Medical Center Petach Tikva Israel Department of Division of Oncology Rambam Health Care Center Haifa Israel Department of Molecular Cell Biology Weizmann Institute of Science Rehovot Israel Department of Computer Science and Applied Mathematics Weizmann Institute of Science Rehovot Israel Department of Mathematics and Computer Science The Open University of Israel Ra’anana Israel Department of Thoracic Surgery Rambam Health Care Center Haifa Israel Nuffield Department of Surgery University of Oxford Oxford UK Division of Surgery Department of Clinical Science Intervention and Technology Karolinska Institute Stockholm Sweden Department of Upper Abdominal Diseases Karolinska University Hospital Stockholm Sweden CIFAR Humans & the Microbiome Program CIFAR Toronto Canada

Background Despite continuous improvement in long-term survival after esophagectomy, potential serious post-operative complications, such as anastomotic leaks (ALs), still occur. Several risk factors for ALs have been proposed, including environmental factors. Our main objective was to examine the correlation of esophageal tumor microbiome composition and functional profile with ALs. Additionally, we analyzed the microbiome of esophageal tumors and their potential correlation with clinical features of the patients. Materials and methods Surgical specimens of esophageal tumors and adjacent normal tissues were collected from consecutive patients who underwent an esophagectomy. Formalin-fixed paraffin-embedded (FFPE) tissue samples were processed using 16S ribosomal DNA multiple fragments amplicon sequencing to characterize bacterial microbiome composition. The tumor and normal tissue microbiome and bacterial functional profile were analyzed based on the clinical outcome of ALs. Results Out of 60 patients who met the inclusion criteria, 52 (86.7%) patients had both normal adjacent tissue (NAT) and tumor (T) FFPE samples included with sufficient bacterial DNA extracted for analysis. A total of 28% of participants had esophageal ALs. Proportion tests [ P < 0.05, false discovery rate (FDR) < 0.25] revealed operational taxonomic units (OTUs) significantly present in T samples as opposed to NAT samples, as well as significantly present OTUs in patients with AL as opposed to patients without AL complication. Conclusions In this study, we provide a profile of the understudied esophageal microbiome and its connection to ALs. Our results can provide potential clues on how to avoid ALs by considering a patient’s personal microbiome when providing perioperative care.

关键词： microbiome tumor microbiome esophageal cancer esophagectomy anastomotic leak

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The Hydrogen Intensity Real-Time Analysis eXperiment: Overview and Status Update

The Hydrogen Intensity Real-Time Analysis eXperiment: Overvi...

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European Conference on Antennas and Propagation, EuCAP

作者： Anthony Walters Keshav Bechoo Shruti Bhatporia H. Cynthia Chiang Devin Crichton Jacobus Diener Sindhu Gaddam Kit Gerodias Austin Gumba Neeraj Gupta Surajit Kalita Emily Kuhn Martin Kunz Kavilan Moodley Warren Naidoo Viraj Nistane Tasmiya Papiah Aditi Pattabhiraman Aritha Pillay Alice Pisani Isibabale Qhoboshiyane Alexandre Refregier Edwin Retana-Montenegro Benjamin R. B. Saliwanchik Ajith Sampath Tsepo Sekhoasha Mugundhan Vijayaraghavan Amanda Weltman Astrophysics Research Centre University of KwaZulu-Natal Westville Campus Durban South Africa School of Mathematics Statistics & Computer Science University of KwaZulu-Natal Westville Campus Durban South Africa Department of Mathematics and Applied Mathematics High Energy Physics Cosmology & Astrophysics Theory (HEPCAT) Group University of Cape Town Cape Town South Africa Department of Physics McGill University Quebec Canada Institute for Particle Physics and Astrophysics ETH Zürich Zürich Switzerland Department of Physics and Astronomy Botswana International University of Science and Technology Palapye Botswana Inter-University Centre for Astronomy and Astrophysics Pune India NASA Jet Propulsion Laboratory California Institute of Technology Pasadena CA USA Département de Physique Théorique and Centre for Astroparticle Physics Université de Genève Geneva Switzerland Stanford University Stanford CA Center for Computational Astrophysics Flatiron Institute New York NY USA The Cooper Union for the Advancement of Science and Art New York NY USA Department of Electronic and Computer Engineering Durban University of Technology Durban South Africa Department of Astrophysical Sciences Peyton Hall Princeton University Princeton NJ USA Instrumentation Division Brookhaven National Laboratory Upton NY USA Onsala Space Observatory Chalmers University of Technology Gothenburg Sweden

The Hydrogen Intensity Real-time Analysis eXperiment (HIRAX) will be a large interferometric array of drift-scan radio telescopes designed to map the large-scale spatial fluctuations of neutral hydrogen in the Universe, in order to better understand the nature of dark energy. It will operate between 400–800 MHz, and is currently under construction in the Karoo desert of South Africa. It will also be a powerful tool for studying astronomical transients and the evolution of galaxies. Here we present an overview of the project, its anticipated deployment timelines, and highlight some of the characterisation and calibration efforts that are currently underway, or planned for the future.

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Heralding Single Photons from a Photon Pair Source using a Superconducting Nanowire Detector

Heralding Single Photons from a Photon Pair Source using a S...

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Quantum 2.0, QUANTUM 2022

作者： Davis, Samantha I. Mueller, Andrew Valivarthi, Raju Lauk, Nikolai Narvaez, Lautaro Korzh, Boris Beyer, Andrew D. Colangelo, Marco Berggren, Karl K. Shaw, Matthew D. Sinclair, Neil Spiropulu, Maria Division of Physics Mathematics and Astronomy California Institute of Technology 1200 E California Blvd. PasadenaCA91125 United States California Institute of Technology 1200 E California Blvd. PasadenaCA91125 United States Jet Propulsion Laboratory California Institute of Technology 4800 Oak Grove Dr. PasadenaCA91109 United States Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology 50 Vassar St. CambridgeMA02139 United States John A. Paulson School of Engineering and Applied Sciences Harvard University 29 Oxford St. CambridgeMA02138 United States

We experimentally demonstrate an improved heralded single photon source using a photon-number-resolving superconducting nanowire detector compared to that using a conventional bucket detector. This work delineates a p... 详细信息

ISBN: (纸本)9781957171111

关键词： Photons

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Heralding Single Photons using Photon-number-resolving Superconducting Nanowires

Heralding Single Photons using Photon-number-resolving Super...

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CLEO: QELS_Fundamental science, QELS 2022

ISBN: (纸本)9781557528209

We improve a single photon source based on spontaneous parametric down-conversion by heralding one of the output modes using a photon number resolving superconducting nanowire detector. We measure a reduced magnitude of the second order cross correlation of one of the output modes conditioned on detection of a single photon in the other mode. © Optica Publishing Group 2022, © 2022 The Author(s)

关键词： Photons

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Retraction Note: Overlapping gait pattern recognition using regression learning for elderly patient monitoring

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Journal of Ambient Intelligence and Humanized Computing 2024年第1期15卷 265-265页

作者： Youssef, Ahmed E. Kotb, Yasser Fouad, Hassan Mustafa, Ibrahim College of Computer and Information Sciences King Saud University Riyadh Saudi Arabia Department of Computers and Systems Engineering Faculty of Engineering at Helwan Helwan University Cairo Egypt Computer Science Division Department of Mathematics Faculty of Science Ain Shams University Cairo Egypt Applied Medical Science Department Community College King Saud University Riyadh Saudi Arabia Biomedical Engineering Department Faculty of Engineering Helwan University Cairo Egypt

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Symptoms of anxiety and depression among health and social science students: A multicenter study

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Heliyon 2025年第2期11卷 e41957页

作者： Pinho, Lara Guedes Engström, Maria Schneider, Brooke C. Fonseca, Cesar Lindberg, Magnus Schröder, Johanna Afonso, Anabela Jelinek, Lena Börsting, Johanna Jacinto, Gonçalo Nilsson, Annika Nursing Department University of Évora Évora 7000-811 Portugal Comprehensive Health Research Centre LA_REAL University of Évora Évora 7000-811 Portugal Department of Caring Science Faculty of Health and Occupational Studies University of Gävle Gävle 801 76 Sweden Department of Psychiatry and Psychotherapy University Medical Center Hamburg-Eppendorf Martinistrasse 52 Hamburg 20246 Germany Department for Psychology Institute for Clinical Psychology and Psychotherapy Medical School Hamburg Hamburg 20457 Germany CIMA IIFA University of Évora Évora 7002 - 554 Portugal Mathematics Department University of Évora ECT Évora 7000-671 Portugal Institute of Computer Science University of Applied Sciences Ruhr West Bottrop Germany

Background: The mental health of university students is a global concern, with high rates of depression and anxiety that need to be addressed. Aim: We aimed to compare the mental health of Portuguese, Swedish and German university students in the health and social sciences following the Covid-19 pandemic and to analyze the factors associated with depressive and anxious symptoms in each country. Methods: A cross-sectional study with a sample of students from Portugal, Germany and Sweden was conducted. Data from online questionnaires, including a sociodemographic and clinical questionnaire, the Patient Health Questionnaire (PHQ-9), the General Anxiety Disorder (GAD-7) and the MHI-5 (Mental Health Inventory) was collected from October to December 2022. Results: The sample was composed of 1670 university students. The prevalence of mild to severe depressive symptoms was 72.7 % in Germany, 62.9 % in Sweden, and 60.3 % in Portugal and the prevalence of mild to severe anxiety symptoms was 78.6 % in Portugal, 73.7 % in Germany, and 66.9 % in Sweden. Being a female student, having a previous mental health disorder diagnosis, and poor academic performance were associated with higher severity of depression and anxiety symptoms in all three countries. Country-specific factors associated with more depressive and/or anxiety symptoms were younger age, smoking, low socioeconomic level and living away from home. Swedish students who do not consume alcohol had more anxiety symptoms and German students who do not consume alcohol had more depressive symptoms. Conclusion: The high prevalence of depressive and anxiety symptoms among students in the three countries highlights the need to address modifiable factors that contribute to this mental health burden. Our results, which are in line with international trends, underline the need for policy reforms that target the main determinants of mental health, in particular by improving socio-economic conditions. Addressing these factors could

关键词： Anxiety Cross-sectional study Depression Mental health University students

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Pass-Efficient randomized lu algorithms for computing low-rank matrix approximation

arXiv

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arXiv 2020年

作者： Zhang, Bolong Mascagniy, Michael Department of Computer Science Florida State University FL United States Applied and Computational Mathematics Division NIST GaithersburgMD United States

Low-rank matrix approximation is extremely useful in the analysis of data that arises in scientific computing, engineering applications, and data science. However, as data sizes grow, traditional low-rank matrix approximation methods, such as singular value decomposition (SVD) and column pivoting QR decomposition (CPQR), are either prohibitively expensive or cannot provide sufficiently accurate results. A solution is to use randomized low-rank matrix approximation methods such as randomized SVD , and randomized LU decomposition on extremely large data sets. In this paper, we focus on the randomized LU decomposition method. First, we employ a reorthogonalization procedure to perform the power iteration of the existing randomized LU algorithm to compensate for the rounding errors caused by the power method. Then we propose a novel randomized LU algorithm, called PowerLU, for the fixed low-rank approximation problem. PowerLU allows for an arbitrary number of passes of the input matrix, v = 2. Recall that the existing randomized LU decomposition only allows an even number of passes. We prove the theoretical relationship between PowerLU and the existing randomized LU. Numerical experiments show that our proposed PowerLU is generally faster than the existing randomized LU decomposition, while remaining accurate. We also propose a version of PowerLU, called PowerLU FP, for the fixed precision low-rank matrix approximation problem. PowerLU FP is based on an efficient blocked adaptive rank determination Algorithm 4.1 proposed in this paper. We present numerical experiments that show that PowerLU FP can achieve almost the same accuracy and is faster than the randomized blocked QB algorithm by Martinsson and Voronin. We finally propose a single-pass algorithm based on LU factorization. Tests show that the accuracy of our single-pass algorithm is comparable with the existing single-pass *** Codes 65F99, 65C99 Copyright © 2020, The Authors. All rights reserved.

关键词： Singular value decomposition

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Colloidal Dynamics on a Choreographic Time Crystal

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Physical Review Letters 2020年第20期124卷 208004-208004页

作者： András Libál Tünde Balázs C. Reichhardt C. J. O. Reichhardt Theoretical Division and Center for Nonlinear Studies Los Alamos National Laboratory Los Alamos New Mexico 87545 USA Mathematics and Computer Science Department Babeş-Bolyai University Cluj 400084 Romania

A choreographic time crystal is a dynamic lattice structure in which the points comprising the lattice move in a coordinated fashion. These structures were initially proposed for understanding the motion of synchronized satellite swarms. Using simulations, we examine colloids interacting with a choreographic crystal consisting of traps that could be created optically. As a function of the trap strength, speed, and colloidal filling fraction, we identify a series of phases including states where the colloids organize into a dynamic chiral loop lattice as well as a frustrated induced liquid state and a choreographic lattice state. We show that transitions between these states can be understood in terms of vertex frustration effects that occur during a certain portion of the choreographic cycle. Our results can be generalized to a broader class of systems of particles coupled to choreographic structures, such as vortices, ions, cold atoms, and soft matter systems.

关键词： Crystal symmetry Colloids Dynamical systems Optical tweezers

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Optimal transport reveals dynamic gene regulatory networks via gene velocity estimation

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PLoS Computational Biology 2025年第5 May期21卷 e1012476页

作者： Zhao, Wenjun Larschan, Erica Sandstede, Björn Singh, Ritambhara Division of Applied Mathematics Brown University ProvidenceRI United States Department of Mathematics University of British Columbia Vancouver Canada Department of Molecular Biology Cell Biology and Biochemistry Center for Computational Molecular Biology Brown University ProvidenceRI United States Department of Computer Science Center for Computational Molecular Biology Brown University ProvidenceRI United States

Inferring gene regulatory networks from gene expression data is an important and challenging problem in the biology community. We propose OTVelo, a methodology that takes time-stamped single-cell gene expression data as input and predicts gene regulation across two time points. It is known that the rate of change of gene expression, which we will refer to as gene velocity, provides crucial information that enhances such inference;however, this information is not always available due to the limitations in sequencing depth. Our algorithm overcomes this limitation by estimating gene velocities using optimal transport. We then infer gene regulation using time-lagged correlation and Granger causality via regularized linear regression. Instead of providing an aggregated network across all time points, our method uncovers the underlying dynamical mechanism across time points. We validate our algorithm on 13 simulated datasets with both synthetic and curated networks and demonstrate its efficacy on 9 experimental data sets. © 2025 Zhao et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

关键词： Transcription

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