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arXiv 2023年

作者： Kofler, Florian Möller, Hendrik Buchner, Josef A. de la Rosa, Ezequiel Ezhov, Ivan Rosier, Marcel Mekki, Isra Shit, Suprosanna Negwer, Moritz Al-Maskari, Rami Ertürk, Ali Vinayahalingam, Shankeeth Isensee, Fabian Pati, Sarthak Rueckert, Daniel Kirschke, Jan S. Ehrlich, Stefan K. Reinke, Annika Menze, Bjoern Wiestler, Benedikt Piraud, Marie Helmholtz AI Helmholtz Munich Neuherberg Germany Department of Computer Science TUM School of Computation Information and Technology Technical University of Munich Munich Germany TranslaTUM - Central Institute for Translational Cancer Research Technical University of Munich Munich Germany Department of Diagnostic and Interventional Neuroradiology School of Medicine Klinikum Rechts der Isar Technical University of Munich Munich Germany Department of Radiation Oncology School of Medicine Klinikum Rechts der Isar Technical University of Munich Munich Germany Icometrix Leuven Belgium Helmholtz Munich Neuherberg Germany University Hospital LMU Munich Munich Germany Munich Germany Munich Germany Department of Oral and Maxillofacial Surgery Radboud University Medical Center Nijmegen Nijmegen Netherlands Department of Artificial Intelligence Radboud University Medical Center Nijmegen Nijmegen Netherlands Department of Oral and Maxillofacial Surgery University Hospital Münster Münster Germany Applied Computer Vision Lab Helmholtz Imaging Hamburg Germany Heidelberg Germany Department of Pathology and Laboratory Medicine Indiana University School of Medicine Indianapolis United States Imperial College London London United Kingdom Healthcare Technologies SETLabs Research GmbH Munich Germany Heidelberg University Heidelberg Germany Department of Quantitative Biomedicine University of Zurich Zurich Switzerland

This paper introduces panoptica, a versatile and performance-optimized package designed for computing instance-wise segmentation quality metrics from 2D and 3D segmentation maps. panoptica addresses the limitations of existing metrics and provides a modular framework that complements the original IOU-based Panoptic Quality with other metrics, such as the distance metric ASSD. The package is open-source, implemented in Python, and accompanied by comprehensive documentation and tutorials. panoptica employs a three-step metrics computation process to cover diverse use cases. We demonstrate the efficacy of panoptica on various real-world biomedical datasets, where an instance-wise evaluation is instrumental for an accurate representation of the underlying clinical task. Overall, we envision panoptica as a valuable tool facilitating in-depth evaluation of segmentation methods. Copyright © 2023, The Authors. All rights reserved.

关键词： Python

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SoccerNet 2023 Challenges Results

arXiv

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arXiv 2023年

作者： Cioppa, Anthony Giancola, Silvio Somers, Vladimir Magera, Floriane Zhou, Xin Mkhallati, Hassan Deliège, Adrien Held, Jan Hinojosa, Carlos Mansourian, Amir M. Miralles, Pierre Barnich, Olivier De Vleeschouwer, Christophe Alahi, Alexandre Ghanem, Bernard Van Droogenbroeck, Marc Kamal, Abdullah Maglo, Adrien Clapés, Albert Abdelaziz, Amr Xarles, Artur Orcesi, Astrid Scott, Atom Liu, Bin Lim, Byoungkwon Chen, Chen Deuser, Fabian Yan, Feng Yu, Fufu Shitrit, Gal Wang, Guanshuo Choi, Gyusik Kim, Hankyul Guo, Hao Fahrudin, Hasby Koguchi, Hidenari Ardö, Håkan Salah, Ibrahim Yerushalmy, Ido Muhammad, Iftikar Uchida, Ikuma Be'ery, Ishay Rabarisoa, Jaonary Lee, Jeongae Fu, Jiajun Yin, Jianqin Xu, Jinghang Nang, Jongho Denize, Julien Li, Junjie Zhang, Junpei Kim, Juntae Synowiec, Kamil Kobayashi, Kenji Zhang, Kexin Habel, Konrad Nakajima, Kota Jiao, Licheng Ma, Lin Wang, Lizhi Wang, Luping Li, Menglong Zhou, Mengying Nasr, Mohamed Abdelwahed, Mohamed Liashuha, Mykola Falaleev, Nikolay Oswald, Norbert Jia, Qiong Pham, Quoc-Cuong Song, Ran Hérault, Romain Peng, Rui Chen, Ruilong Liu, Ruixuan Baikulov, Ruslan Fukushima, Ryuto Escalera, Sergio Lee, Seungcheon Chen, Shimin Ding, Shouhong Someya, Taiga Moeslund, Thomas B. Li, Tianjiao Shen, Wei Zhang, Wei Li, Wei Dai, Wei Luo, Weixin Zhao, Wending Zhang, Wenjie Yang, Xinquan Ma, Yanbiao Joo, Yeeun Zeng, Yingsen Gan, Yiyang Zhu, Yongqiang Zhong, Yujie Ruan, Zheng Li, Zhiheng Huang, Zhijian Meng, Ziyu Belgium Saudi Arabia Sportradar Norway UCLouvain Belgium EPFL Switzerland EVS Broadcast Equipment Belgium Baidu Research United States Belgium Sharif University of Technology Iran Footovision France Zewail City of Science Technology and Innovation Egypt Université Paris-Saclay CEA France Universitat de Barcelona Spain Computer Vision Center Spain Nagoya University Japan Research Center for Applied Mathematics and Machine Intelligence Zhejiang Lab China AIBrain United States OPPO Research Institute China Germany Meituan China Tencent Youtu Lab China Amazon Prime Video Sport United States Sogang University Korea Republic of The University of Tokyo Japan Spiideo Sweden University of Tsukuba Japan School of Artificial Intelligence Beijing University of Posts and Telecommunications China Normandie Univ INSA Rouen LITIS France Shanghai Jiao Tong University China Key Laboratory of Intelligent Perception and Image Understanding The Ministry of Education Xidian University China NASK - National Research Institute Poland Robo Space China Tongji University China Sportlight Technology United Kingdom School of Control Science and Engineering Shandong University China lRomul Russia Aalborg University Denmark Turing AI Cultures GmbH Germany Information Systems Technology and Design Singapore University of Technology and Design Singapore Sun Yat-sen University China

The SoccerNet 2023 challenges were the third annual video understanding challenges organized by the SoccerNet team. For this third edition, the challenges were composed of seven vision-based tasks split into three main themes. The first theme, broadcast video understanding, is composed of three high-level tasks related to describing events occurring in the video broadcasts: (1) action spotting, focusing on retrieving all timestamps related to global actions in soccer, (2) ball action spotting, focusing on retrieving all timestamps related to the soccer ball change of state, and (3) dense video captioning, focusing on describing the broadcast with natural language and anchored timestamps. The second theme, field understanding, relates to the single task of (4) camera calibration, focusing on retrieving the intrinsic and extrinsic camera parameters from images. The third and last theme, player understanding, is composed of three low-level tasks related to extracting information about the players: (5) re-identification, focusing on retrieving the same players across multiple views, (6) multiple object tracking, focusing on tracking players and the ball through unedited video streams, and (7) jersey number recognition, focusing on recognizing the jersey number of players from tracklets. Compared to the previous editions of the SoccerNet challenges, tasks (2-3-7) are novel, including new annotations and data, task (4) was enhanced with more data and annotations, and task (6) now focuses on end-to-end approaches. More information on the tasks, challenges, and leader-boards are available on https://***. Baselines and development kits can be found on https://***/SoccerNet. © 2023, CC BY.

关键词： computer vision

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Lessons Learned from Assessing Trustworthy AI in Practice

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Digital Society 2023年第3期2卷 1-25页

作者： Vetter, Dennis Amann, Julia Bruneault, Frédérick Coffee, Megan Düdder, Boris Gallucci, Alessio Gilbert, Thomas Krendl Hagendorff, Thilo van Halem, Irmhild Hickman, Eleanore Hildt, Elisabeth Holm, Sune Kararigas, Georgios Kringen, Pedro Madai, Vince I. Wiinblad Mathez, Emilie Tithi, Jesmin Jahan Westerlund, Magnus Wurth, Renee Zicari, Roberto V. Computational Vision and Artificial Intelligence Lab Goethe University Frankfurt Frankfurt Am Main Germany Z-Inspection® Initiative Venice Italy Health Ethics and Policy Lab ETH Zurich Zurich Switzerland Strategy and Innovation Careum Foundation Zurich Switzerland Philosophie Departement Collège André-Laurendeau Montréal Canada École Des Médias Université du Québec À Montréal Montréal Canada Department of Medicine Division of Infectious Diseases and Immunology New York University Grossman School of Medicine New York City USA Department of Computer Science University of Copenhagen Copenhagen Denmark Digital Life Initiative Cornell Tech New York City USA Cluster of Excellence “Machine Learning: New Perspectives for Science” University of Tuebingen Tuebingen Germany School of Law University of Bristol Bristol UK Center for the Study of Ethics in the Professions Illinois Institute of Technology Chicago USA Department of Business Management and Analytics Arcada University of Applied Sciences Helsinki Finland Department of Food & Resource Economics University of Copenhagen Copenhagen Denmark Department of Physiology Faculty of Medicine University of Iceland Reykjavik Iceland QUEST Centre for Responsible Research Berlin Institute of Health Charité Universitätsmedizin Berlin Berlin Germany Faculty of Computing Engineering and the Built Environment School of Computing and Digital Technology Birmingham City University Birmingham UK Parallel Computing Labs Intel Santa Clara USA School of Economics Innovation and Technology Kristiania University College Oslo Norway Data Science Graduate School Seoul National University Seoul South Korea

Building artificial intelligence (AI) systems that adhere to ethical standards is a complex problem. Even though a multitude of guidelines for the design and development of such trustworthy AI systems exist, these guidelines focus on high-level and abstract requirements for AI systems, and it is often very difficult to assess if a specific system fulfills these requirements. The Z-Inspection® process provides a holistic and dynamic framework to evaluate the trustworthiness of specific AI systems at different stages of the AI lifecycle, including intended use, design, and development. It focuses, in particular, on the discussion and identification of ethical issues and tensions through the analysis of socio-technical scenarios and a requirement-based framework for ethical and trustworthy AI. This article is a methodological reflection on the Z-Inspection® process. We illustrate how high-level guidelines for ethical and trustworthy AI can be applied in practice and provide insights for both AI researchers and AI practitioners. We share the lessons learned from conducting a series of independent assessments to evaluate the trustworthiness of real-world AI systems, as well as key recommendations and practical suggestions on how to ensure a rigorous trustworthiness assessment throughout the lifecycle of an AI system. The results presented in this article are based on our assessments of AI systems in the healthcare sector and environmental monitoring, where we used the framework for trustworthy AI proposed in the Ethics Guidelines for Trustworthy AI by the European Commission’s High-Level Expert Group on AI. However, the assessment process and the lessons learned can be adapted to other domains and include additional frameworks.

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The ZTF Source Classification Project: III. A Catalog of Variable Sources

arXiv

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arXiv 2023年

作者： Healy, Brian F. Coughlin, Michael W. Mahabal, Ashish A. Laz, Theophile Jegou du Drake, Andrew Graham, Matthew J. Hillenbrand, Lynne A. van Roestel, Jan Szkody, Paula Zielske, LeighAnna Guiga, Mohammed Hassan, Muhammad Yusuf Hughes, Jill L. Nir, Guy Parikh, Saagar Park, Sungmin Purohit, Palak Rebbapragada, Umaa Reed, Draco Warshofsky, Daniel Wold, Avery Bloom, Joshua S. Masci, Frank J. Riddle, Reed Smith, Roger School of Physics and Astronomy University of Minnesota MinneapolisMN55455 United States Division of Physics Mathematics and Astronomy California Institute of Technology PasadenaCA91125 United States Center for Data Driven Discovery California Institute of Technology PasadenaCA91125 United States Department of Astronomy California Institute of Technology PasadenaCA91125 United States Anton Pannekoek Institute for Astronomy University of Amsterdam Amsterdam1090 GE Netherlands Department of Astronomy University of Washington SeattleWA98195 United States Department of Physics Pacific Lutheran University TacomaWA98447 United States Department of Computer Science and Engineering University of Minnesota MinneapolisMN55455 United States Department of Electrical Engineering Indian Institute of Technology Gandhinagar Gujarat 382055 India Department of Astronomy University of California BerkeleyCA94720 United States Lawrence Berkeley National Laboratory 1 Cyclotron Road MS 50B-4206 BerkeleyCA94720 United States Department of Electrical and Computer Engineering Carnegie Mellon University PittsburghPA15213 United States Computer Vision Imaging and Graphics Lab Indian Institute of Technology Gujarat Gandhinagar382055 India School of Statistics University of Minnesota MinneapolisMN55455 United States Division of Engineering and Applied Science California Institute of Technology PasadenaCA91125 United States Jet Propulsion Laboratory California Institute of Technology PasadenaCA91125 United States IPAC California Institute of Technology 1200 E. California Blvd. PasadenaCA91125 United States Caltech Optical Observatories California Institute of Technology PasadenaCA91125 United States

The classification of variable objects provides insight into a wide variety of astrophysics ranging from stellar interiors to galactic nuclei. The Zwicky Transient Facility (ZTF) provides time-series observations that record the variability of more than a billion sources. The scale of these data necessitates automated approaches to make a thorough analysis. Building on previous work, this paper reports the results of the ZTF Source Classification Project (SCoPe), which trains neural network and XGBoost machine-learning (ML) algorithms to perform dichotomous classification of variable ZTF sources using a manually constructed training set containing 170,632 light curves. We find that several classifiers achieve high precision and recall scores, suggesting the reliability of their predictions for 209,991,147 light curves across 77 ZTF fields. We also identify the most important features for XGB classification and compare the performance of the two ML algorithms, finding a pattern of higher precision among XGB classifiers. The resulting classification catalog is available to the public, and the software developed for SCoPe is open-source and adaptable to future time-domain surveys. Copyright © 2023, The Authors. All rights reserved.

关键词： Classification (of information)

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Anonymization of labeled TOF-MRA images for brain vessel segmentation using generative adversarial networks

arXiv

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arXiv 2020年

作者： Kossen, Tabea Subramaniam, Pooja Madai, Vince I. Hennemuth, Anja Hildebrand, Kristian Hilbert, Adam Sobesky, Jan Livne, Michelle Galinovic, Ivana Khalil, Ahmed A. Fiebach, Jochen B. Frey, Dietmar CLAIM - Charité Lab for AI in Medicine Charité Universitätsmedizin Berlin Germany Department of Computer Engineering and Microelectronics Computer Vision & Remote Sensing Technical University Berlin Berlin Germany Department of Electrical Engineering and Computer Science Technical University of Berlin Berlin Germany School of Computing and Digital Technology Faculty of Computing Engineering and the Built Environment Birmingham City University Birmingham United Kingdom Institute for Imaging Science and Computational Modelling in Cardiovascular Medicine Charité Universitätsmedizin Berlin Berlin Germany Fraunhofer MEVIS Bremen Germany Department VI Computer Science and Media Beuth University of Applied Sciences Berlin Germany Johanna-Etienne-Hospital Neuss Germany Centre for Stroke Research Berlin Charité Universitätsmedizin Berlin Berlin Germany Department of Neurology Max Planck Institute for Human Cognitive and Brain Sciences Leipzig Germany Mind Brain Body Institute Berlin School of Mind and Brain Humboldt University Berlin Berlin Germany Berlin Institute of Health Berlin Germany

Anonymization and data sharing are crucial for privacy protection and acquisition of large datasets for robust medical image analysis. This represents a major challenge, especially for brain imaging research. Here, the unique structure of brain images allows for potential re-identification and thus requires anonymization beyond conventional methods. Generative adversarial networks (GANs) have the potential to provide anonymous images while maintaining their predictive properties. Analyzing brain vessel segmentation as a use case, we trained 3 GAN architectures on time-of-flight (TOF) magnetic resonance angiography (MRA) patches of patients with cerebrovascular disease for image-label pair generation: 1) Deep convolutional GAN, 2) Wasserstein-GAN with gradient penalty (WGAN-GP) and 3) WGAN-GP with spectral normalization (WGAN-GP-SN). First, the synthesized image-labels from each GAN architecture were used to train a U-net for vessel segmentation. The U-nets were then tested on real patient data. In total, 66 patients were used for this analysis. In a second step, we simulated the application of our synthetic patches in a transfer learning approach using a second, independent dataset. Here, for an increasing number of up to 15 patients we evaluated vessel segmentation model performance on real data with and without pre-training on generated patches. Finally, performance for all models was assessed by the Dice Similarity Coefficient (DSC) and the 95th percentile of the Hausdorff Distance (95HD). Comparing the 3 GAN architectures, the U-net model trained on synthetic data generated by the WGAN-GP-SN showed the highest performance to predict brain vessels (DSC/95HD 0.82/28.97) benchmarked by the U-net trained on real data (0.89/26.61). The transfer learning approach showed superior performance for the same GAN architecture compared to no pre-training, especially for one labeled patient only (DSC/95HD 0.91/25.68 compared to DSC/95HD 0.85/27.36). In a brain imaging segment

关键词： Image segmentation

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Band selection for oxygenation estimation with multispectral/hyperspectral imaging

arXiv

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arXiv 2019年

作者： Ayala, Leonardo Isensee, Fabian Wirkert, Sebastian J. Vemuri, Anant S. Maier-Hein, Klaus H. Fei, Baowei Maier-Hein, Lena Heidelberg Germany Heidelberg Germany Department of Bioengineering The University of Texas at Dallas RichardsonTX United States Advanced Imaging Research Center The University of Texas Southwestern Medical Center DallasTX United States Department of Radiology The University of Texas Southwestern Medical Center DallasTX United States Applied Computer Vision Lab. Helmholtz Imaging Medical Faculty Heidelberg University Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany

Multispectral imaging provides valuable information on tissue composition such as hemoglobin oxygen saturation. However, the real-time application of this technique in interventional medicine can be challenging due to the long acquisition times needed for large amounts of hyperspectral data with hundreds of bands. While this challenge can partially be addressed by choosing a discriminative subset of bands, the band selection methods proposed to date are mainly restricted by the availability of often hard to obtain reference measurements. We address this bottleneck with a new approach to band selection that leverages highly accurate Monte Carlo (MC) simulations. We hypothesize that a so chosen small subset of bands can reproduce or even improve upon the results of a quasi continuous spectral measurement. We further investigate whether novel domain adaptation techniques can address the inevitable domain shift stemming from the use of simulations. Initial results based on in silico and in vivo experiments suggest that 10-20 bands are sufficient to closely reproduce results from spectral measurements with 101 bands in the 500-700 nm range. The investigated domain adaptation technique, which only requires unlabeled in vivo measurements, yielded better results than the pure in silico band selection method. Overall, our method could guide development of fast multispectral imaging systems suited for interventional use without relying on complex hardware setups or manually labeled data. Copyright © 2019, The Authors. All rights reserved.

关键词： Machine learning

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Metrics Reloaded: Recommendations for image analysis validation

arXiv

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arXiv 2022年

作者： Maier-Hein, Lena Reinke, Annika Godau, Patrick Tizabi, Minu D. Buettner, Florian Christodoulou, Evangelia Glocker, Ben Isensee, Fabian Kleesiek, Jens Kozubek, Michal Reyes, Mauricio Riegler, Michael A. Wiesenfarth, Manuel Emre Kavur, A. Sudre, Carole H. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Rädsch, Tim Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Jorge Cardoso, M. Cheplygina, Veronika Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian Ginneken, Bram Van Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kofler, Florian Kopp-Schneider, Annette Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rajpoot, Nasir Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Smeden, Maarten Van Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben Van Varoquaux, Gaël Jäger, Paul F. Heidelberg Division of Intelligent Medical Systems and HI Helmholtz Imaging Germany Faculty of Mathematics and Computer Science and Medical Faculty Heidelberg University Heidelberg Germany NCT Heidelberg a partnership between DKFZ University Medical Center Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt-Marburg Germany Heidelberg Goethe University Frankfurt Germany Department of Medicine Goethe University Frankfurt Germany Department of Informatics Frankfurt Cancer Insititute Germany Department of Computing Imperial College London London United Kingdom Heidelberg Division of Medical Image Computing and HI Applied Computer Vision Lab Germany Institute for AI in Medicine University Medicine Essen Essen Germany Centre for Biomedical Image Analysis Faculty of Informatics Masaryk University Brno Czech Republic ARTORG Center for Biomedical Engineering Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Bern Switzerland Simula Metropolitan Center for Digital Engineering Oslo Norway UiT The Arctic University of Norway Romsø Norway Heidelberg Division of Biostatistics Germany Heidelberg Division of Intelligent Medical Systems Division of Medical Image Computing HI Applied Computer Vision Lab Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Heidelberg Division of Medical Image Computing Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain interest, thus failing to adequately measure scientific progress and hindering translation of ML techniques into practice. To overcome this, we created Metrics Reloaded, a comprehensive framework guiding researchers in the problem-aware selection of metrics. It was developed by a large international consortium in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint – a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output. Based on the problem fingerprint, users are guided through the process of choosing and applying appropriate validation metrics while being made aware of potential pitfalls. Metrics Reloaded targets image analysis problems that can be interpreted as a classification task at image, object or pixel level, namely image-level classification, object detection, semantic segmentation, and instance segmentation tasks. To improve the user experience, we implemented the framework in the Metrics Reloaded online tool. Following the convergence of ML methodology across application domains, Metrics Reloaded fosters the convergence of validation methodology. Its applicability is demonstrated for various biomedical use cases. © 2022, CC BY.

关键词： Semantic Segmentation

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Assessing Trustworthy AI in Times of COVID-19: Deep Learning for Predicting a Multiregional Score Conveying the Degree of Lung Compromise in COVID-19 Patients

IEEE Transactions on Technology and Society

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IEEE Transactions on Technology and Society 2022年第4期3卷 272-289页

作者： Allahabadi, Himanshi Amann, Julia Balot, Isabelle Beretta, Andrea Binkley, Charles Bozenhard, Jonas Bruneault, Frederick Brusseau, James Candemir, Sema Cappellini, Luca Alessandro Chakraborty, Subrata Cherciu, Nicoleta Cociancig, Christina Coffee, Megan Ek, Irene Espinosa-Leal, Leonardo Farina, Davide Fieux-Castagnet, Genevieve Frauenfelder, Thomas Gallucci, Alessio Giuliani, Guya Golda, Adam Van Halem, Irmhild Hildt, Elisabeth Holm, Sune Kararigas, Georgios Krier, Sebastien A. Kuhne, Ulrich Lizzi, Francesca Madai, Vince I. Markus, Aniek F. Masis, Serg Mathez, Emilie Wiinblad Mureddu, Francesco Neri, Emanuele Osika, Walter Ozols, Matiss Panigutti, Cecilia Parent, Brendan Pratesi, Francesca Moreno-Sanchez, Pedro A. Sartor, Giovanni Savardi, Mattia Signoroni, Alberto Sormunen, Hanna-Maria Spezzatti, Andy Srivastava, Adarsh Stephansen, Annette F. Theng, Lau Bee Tithi, Jesmin Jahan Tuominen, Jarno Umbrello, Steven Vaccher, Filippo Vetter, Dennis Westerlund, Magnus Wurth, Renee Zicari, Roberto V. Ey Netherlands Enterprise Intelligence Department Amsterdam1083 HP Netherlands Eth Zurich Health Ethics and Policy Lab Department of Health Sciences and Technology Zürich8092 Switzerland Center for Diplomatic and Strategic Studies Postgraduate Studies in Diplomacy and International Relations Paris75015 France Pisa56124 Italy Hackensack Meridian Health Bioethics Center EdisonNJ08820 United States University of Oxford Faculty of Philosophy OxfordOX2 6GG United Kingdom Collège André- Laurendeau Philosophie Department MontrealQCH8N 2J4 Canada Université du Québec À Montréal École des Médias MontrealQCH2L 2C4 Canada Pace University Philosophy Department New YorkNY10038 United States The Ohio State University Wexner Medical Center Department of Radiology ColumbusOH43210 United States Humanitas Research Hospital Department of Radiology Milan20089 Italy Humanitas University Department of Biomedical Sciences Milan20089 Italy University of New England Faculty of Science Agriculture Business and Law ArmidaleNSW2351 Australia University of Technology Sydney Faculty of Engineering and Information Technology SydneyNSW2007 Australia Scuola Superiore Sant'Anna European Centre of Excellence on the Regulation of Robotics and Ai Pisa56127 Italy University of Bremen Group of Computer Architecture Bremen28359 Germany New York University Grossman School of Medicine Division of Infectious Diseases and Immunology Department of Medicine New YorkNY10016 United States Digital Institute Ai Research Section Stockholm16731 Sweden Arcada University of Applied Sciences Department of Business Management and Analytics Helsinki00550 Finland University of Brescia Radiological Sciences and Public Health Department of Medical and Surgical Specialties Brescia25121 Italy Sncf Reseau Sa Ethique Groupe La Plaine93418 France Institute of Diagnostic and Interventional Radiology University Hospital Zurich Zürich8091 Switzerland Eindhoven University of Tech

This article's main contributions are twofold: 1) to demonstrate how to apply the general European Union's High-Level Expert Group's (EU HLEG) guidelines for trustworthy AI in practice for the domain of healthcare and 2) to investigate the research question of what does 'trustworthy AI' mean at the time of the COVID-19 pandemic. To this end, we present the results of a post-hoc self-assessment to evaluate the trustworthiness of an AI system for predicting a multiregional score conveying the degree of lung compromise in COVID-19 patients, developed and verified by an interdisciplinary team with members from academia, public hospitals, and industry in time of pandemic. The AI system aims to help radiologists to estimate and communicate the severity of damage in a patient's lung from Chest X-rays. It has been experimentally deployed in the radiology department of the ASST Spedali Civili clinic in Brescia, Italy, since December 2020 during pandemic time. The methodology we have applied for our post-hoc assessment, called Z-Inspection®, uses sociotechnical scenarios to identify ethical, technical, and domain-specific issues in the use of the AI system in the context of the pandemic. © 2020 IEEE.

关键词： COVID-19

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Are we using appropriate segmentation metrics? Identifying correlates of human expert perception for CNN training beyond rolling the DICE coefficient

arXiv

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arXiv 2021年

作者： Kofler, Florian Ezhov, Ivan Isensee, Fabian Balsiger, Fabian Berger, Christoph Koerner, Maximilian Demiray, Beatrice Rackerseder, Julia Paetzold, Johannes Li, Hongwei Shit, Suprosanna McKinley, Richard Piraud, Marie Bakas, Spyridon Zimmer, Claus Navab, Nassir Kirschke, Jan Wiestler, Benedikt Menze, Bjoern Department of Informatics Technical University Munich Germany TranslaTUM - Central Institute for Translational Cancer Research Technical University of Munich Germany Department of Diagnostic and Interventional Neuroradiology School of Medicine Klinikum rechts der Isar Technical University of Munich Germany Applied Computer Vision Lab Helmholtz Imaging Germany Germany Institute for Diagnostic and Interventional Neuroradiology Inselspital Bern University Hospital University of Bern Bern Switzerland Technical University of Munich Germany ImFusion GmbH Munich Germany Helmholtz Zentrum München Germany Imperial College London Exhibition Rd South Kensington LondonSW7 2BX United Kingdom Department of Quantitative Biomedicine University of Zurich Switzerland Helmholtz AI Helmholtz Zentrum München Germany University of Pennsylvania PhiladelphiaPA United States Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Radiology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States

Metrics optimized in complex machine learning tasks are often selected in an ad-hoc manner. It is unknown how they align with human expert perception. We explore the correlations between established quantitative segmentation quality metrics and qualitative evaluations by professionally trained human raters. Therefore, we conduct psychophysical experiments for two complex biomedical semantic segmentation problems. We discover that current standard metrics and loss functions correlate only moderately with the segmentation quality assessment of experts. Importantly, this effect is particularly pronounced for clinically relevant structures, such as the enhancing tumor compartment of glioma in brain magnetic resonance and grey matter in ultrasound imaging. It is often unclear how to optimize abstract metrics, such as human expert perception, in convolutional neural network (CNN) training. To cope with this challenge, we propose a novel strategy employing techniques of classical statistics to create complementary compound loss functions to better approximate human expert perception. Across all rating experiments, human experts consistently scored computer-generated segmentations better than the human-curated reference labels. Our results, therefore, strongly question many current practices in medical image segmentation and provide meaningful cues for future research. © 2021, CC BY.

关键词： Medical imaging

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Why is the Winner the Best?

Why is the Winner the Best?

引用

Conference on computer vision and Pattern Recognition (CVPR)

作者： M. Eisenmann A. Reinke V. Weru M. D. Tizabi F. Isensee T. J. Adler S. Ali V. Andrearczyk M. Aubreville U. Baid S. Bakas N. Balu S. Bano J. Bernal S. Bodenstedt A. Casella V. Cheplygina M. Daum M. De Bruijne A. Depeursinge R. Dorent J. Egger D. G. Ellis S. Engelhardt M. Ganz N. Ghatwary G. Girard P. Godau A. Gupta L. Hansen K. Harada M. Heinrich N. Heller A. Hering A. Huaulmé P. Jannin A. E. Kavur O. Kodym M. Kozubek J. Li H. Li J. Ma C. Martín-Isla B. Menze A. Noble V. Oreiller N. Padoy S. Pati K. Payette T. Rädsch J. Rafael-Patiño V. Singh Bawa S. Speidel C. H. Sudre K. Van Wijnen M. Wagner D. Wei A. Yamlahi M. H. Yap C. Yuan M. Zenk A. Zia D. Zimmerer D. Aydogan B. Bhattarai L. Bloch R. Brüngel J. Cho C. Choi Q. Dou I. Ezhov C. M. Friedrich C. Fuller R. R. Gaire A. Galdran Á. García Faura M. Grammatikopoulou S. Hong M. Jahanifar I. Jang A. Kadkhodamohammadi I. Kang F. Kofler S. Kondo H. Kuijf M. Li M. Luu T. Martinčič P. Morais M. A. Naser B. Oliveira D. Owen S. Pang J. Park S. Park S. Płotka E. Puybareau N. Rajpoot K. Ryu N. Saeed A. Shephard P. Shi D. Štepec R. Subedi G. Tochon H. R. Torres H. Urien J. L. Vilaça K. A. Wahid H. Wang J. Wang L. Wang X. Wang B. Wiestler M. Wodzinski F. Xia J. Xie Z. Xiong S. Yang Y. Yang Z. Zhao K. Maier-Hein P. F. Jäger A. Kopp-Schneider L. Maier-Hein Division of Intelligent Medical Systems German Cancer Research Center (DKFZ) Heidelberg Germany Helmholtz Imaging German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Division of Biostatistics German Cancer Research Center (DKFZ) Heidelberg Germany Division of Medical Image Computing German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Engineering and Physical Sciences School of Computing University of Leeds Leeds UK Institute of Informatics School of Management HES-SO Valais-Wallis University of Applied Sciences and Arts Western Switzerland Sierre Switzerland Department of Nuclear Medicine and Molecular Imaging Lausanne University Hospital Lausanne Switzerland Technische Hochschule Ingolstadt Ingolstadt Germany Center for Artificial Intelligence and Data Science for Integrated Diagnostics (AI2D) and Center for Biomedical Image Computing and Analytics (CBICA) University of Pennsylvania Philadelphia PA USA Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Radiology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Radiology University of Washington Seattle WA USA Department of Computer Science Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS) University College London London UK Universitat Autònoma de Barcelona & Computer Vision Center Barcelona Spain Division of Translational Surgical Oncology National Center for Tumor Diseases (NCT/UCC) Dresden Dresden Germany Department of Advanced Robotics Istituto Italiano di Tecnologia Italy Department of Electronics Information and Bioengineering Politecnico di Milano Milan Italy IT University of Copenhagen Copenhagen Denmark Department of General Visceral and Transplantation Surgery Heidelberg University Hospital Heidelberg Germany Department of Radiology and Nuc

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do they really generate scientific progress? What are common and successful participation strategies? What makes a solution superior to a competing method? To address this gap in the literature, we performed a multicenter study with all 80 competitions that were conducted in the scope of IEEE ISBI 2021 and MICCAI 2021. Statistical analyses performed based on comprehensive descriptions of the submitted algorithms linked to their rank as well as the underlying participation strategies revealed common characteristics of winning solutions. These typically include the use of multi-task learning (63%) and/or multi-stage pipelines (61%), and a focus on augmentation (100%), image preprocessing (97%), data curation (79%), and post-processing (66%). The “typical” lead of a winning team is a computer scientist with a doctoral degree, five years of experience in biomedical image analysis, and four years of experience in deep learning. Two core general development strategies stood out for highly-ranked teams: the reflection of the metrics in the method design and the focus on analyzing and handling failure cases. According to the organizers, 43% of the winning algorithms exceeded the state of the art but only 11% completely solved the respective domain problem. The insights of our study could help researchers (1) improve algorithm development strategies when approaching new problems, and (2) focus on open research questions revealed by this work.

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