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arXiv 2023年

作者： Cui, Yuzhu Hada, Kazuhiro Kawashima, Tomohisa Kino, Motoki Lin, Weikang Mizuno, Yosuke Ro, Hyunwook Honma, Mareki Yi, Kunwoo Yu, Jintao Park, Jongho Jiang, Wu Shen, Zhiqiang Kravchenko, Evgeniya Algaba, Juan-Carlos Cheng, Xiaopeng Cho, Ilje Giovannini, Gabriele Giroletti, Marcello Jung, Taehyun Lu, Ru-Sen Niinuma, Kotaro Oh, Junghwan Ohsuga, Ken Sawada-Satoh, Satoko Sohn, Bong Won Takahashi, Hiroyuki R. Takamura, Mieko Tazaki, Fumie Trippe, Sascha Wajima, Kiyoaki Akiyama, Kazunori An, Tao Asada, Keiichi Buttaccio, Salvatore Byun, Do-Young Cui, Lang Hagiwara, Yoshiaki Hirota, Tomoya Hodgson, Jeffrey Kawaguchi, Noriyuki Kim, Jae-Young Lee, Sang-Sung Lee, Jee Won Lee, Jeong Ae Maccaferri, Giuseppe Melis, Andrea Melnikov, Alexey Migoni, Carlo Oh, Se-Jin Sugiyama, Koichiro Wang, Xuezheng Zhang, Yingkang Chen, Zhong Hwang, Ju-Yeon Jung, Dong-Kyu Kim, Hyo-Ryoung Kim, Jeong-Sook Kobayashi, Hideyuki Li, Bin Li, Guanghui Li, Xiaofei Liu, Zhiyong Liu, Qinghui Liu, Xiang Oh, Chung-Sik Oyama, Tomoaki Roh, Duk-Gyoo Wang, Jinqing Wang, Na Wang, Shiqiang Xia, Bo Yan, Hao Yeom, Jae-Hwan Yonekura, Yoshinori Yuan, Jianping Zhang, Hua Zhao, Rongbing Zhong, Weiye Research Center for Intelligent Computing Platforms Zhejiang Laboratory Hangzhou311100 China Tsung-Dao Lee Institute Shanghai Jiao Tong University 520 Shengrong Road Shanghai201210 China Astronomical Science Program The Graduate University for Advanced Studies SOKENDAI 2-21-1 Osawa Mitaka Tokyo181-8588 Japan Mizusawa VLBI Observatory National Astronomical Observatory of Japan 2-12 Hoshigaoka Mizusawa Iwate Oshu023-0861 Japan Institute for Cosmic Ray Research The University of Tokyo 5-1-5 Kashiwanoha Chiba Kashiwa277-8582 Japan Kogakuin University of Technology & Engineering Academic Support Center 2665-1 Nakano-machi Hachioji Tokyo192-0015 Japan South-Western Institute For Astronomy Research Yunnan University Kunming650500 China School of Physics and Astronomy Shanghai Jiao Tong University Shanghai200240 China Institut für Theoretische Physik Goethe-Universität Frankfurt Max-von-Laue-Straße 1 Frankfurt am MainD-60438 Germany Korea Astronomy & Space Science Institute Daedeokdae-ro 776 Yuseong-gu Daejeon34055 Korea Republic of Department of Astronomy Yonsei University Yonsei-ro 50 Seodaemun-gu Seoul03722 Korea Republic of Department of Astronomy Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo Tokyo113-0033 Japan Department of Physics and Astronomy Seoul National University Gwanak-gu Seoul08826 Korea Republic of Department of Information Countermeasure Air Force Early Warning Academy Wuhan430019 China Institute of Astronomy and Astrophysics Academia Sinica HiloHI96720 United States Shanghai Astronomical Observatory Chinese Academy of Sciences 80 Nandan Road Shanghai200030 China Key Laboratory of Radio Astronomy Chinese Academy of Sciences Beijing100101 China Moscow Institute of Physics and Technology Dolgoprudny Institutsky per. 9 Moscow141700 Russia Lebedev Physical Institute The Russian Academy of Sciences Leninsky prospekt 53 Moscow119991 Russia Department of Physics Faculty of Science U

The nearby radio galaxy M87 offers a unique opportunity to explore the connections between the central supermassive black hole and relativistic jets. Previous studies of the inner region of M87 revealed a wide opening angle for the jet originating near the black hole 1–4. The Event Horizon Telescope resolved the central radio source and found an asymmetric ring structure consistent with expectations from General Relativity 5. With a baseline of 17 years of observations, there was a shift in the jet’s transverse position, possibly arising from an eight to ten-year quasi-periodicity 3. However, the origin of this sideways shift remains unclear. Here we report an analysis of radio observations over 22 years that suggests a period of about 11 years in the position angle variation of the jet. We infer that we are seeing a spinning black hole that induces the Lense-Thirring precession of a misaligned accretion disk. Similar jet precession may commonly occur in other active galactic nuclei but has been challenging to detect owing to the small magnitude and long period of the variation. Copyright © 2023, The Authors. All rights reserved.

关键词： Active Galactic Nuclei

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Search for Gamma-Ray Spectral Lines from Dark Matter Annihilation up to 100 TeV toward the Galactic Center with MAGIC

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Physical Review Letters 2023年第6期130卷 061002-061002页

作者： H. Abe S. Abe V. A. Acciari T. Aniello S. Ansoldi L. A. Antonelli A. Arbet Engels C. Arcaro M. Artero K. Asano D. Baack A. Babić A. Baquero U. Barres de Almeida J. A. Barrio I. Batković J. Baxter J. Becerra González W. Bednarek E. Bernardini M. Bernardos A. Berti J. Besenrieder W. Bhattacharyya C. Bigongiari A. Biland O. Blanch G. Bonnoli Ž. Bošnjak I. Burelli G. Busetto R. Carosi M. Carretero-Castrillo G. Ceribella Y. Chai A. Chilingarian S. Cikota E. Colombo J. L. Contreras J. Cortina S. Covino G. D’Amico V. D’Elia P. Da Vela F. Dazzi A. De Angelis B. De Lotto A. Del Popolo M. Delfino J. Delgado C. Delgado Mendez D. Depaoli F. Di Pierro L. Di Venere E. Do Souto Espiñeira D. Dominis Prester A. Donini D. Dorner M. Doro D. Elsaesser G. Emery V. Fallah Ramazani L. Fariña A. Fattorini L. Font C. Fruck S. Fukami Y. Fukazawa R. J. García López M. Garczarczyk S. Gasparyan M. Gaug J. G. Giesbrecht Paiva N. Giglietto F. Giordano P. Gliwny N. Godinović J. G. Green D. Green D. Hadasch A. Hahn T. Hassan L. Heckmann J. Herrera D. Hrupec M. Hütten R. Imazawa T. Inada R. Iotov K. Ishio I. Jiménez Martínez J. Jormanainen D. Kerszberg Y. Kobayashi H. Kubo J. Kushida A. Lamastra D. Lelas F. Leone E. Lindfors L. Linhoff S. Lombardi F. Longo R. López-Coto M. López-Moya A. López-Oramas S. Loporchio A. Lorini E. Lyard B. Machado de Oliveira Fraga P. Majumdar M. Makariev G. Maneva N. Mang M. Manganaro S. Mangano K. Mannheim M. Mariotti M. Martínez A. Mas Aguilar D. Mazin S. Menchiari S. Mender S. Mićanović D. Miceli T. Miener J. M. Miranda R. Mirzoyan E. Molina H. A. Mondal A. Moralejo D. Morcuende V. Moreno T. Nakamori C. Nanci L. Nava V. Neustroev M. Nievas Rosillo C. Nigro K. Nilsson K. Nishijima T. Njoh Ekoume K. Noda S. Nozaki Y. Ohtani T. Oka J. Otero-Santos S. Paiano M. Palatiello D. Paneque R. Paoletti J. M. Paredes L. Pavletić M. Persic M. Pihet F. Podobnik P. G. Prada Moroni E. Prandini G. Principe C. Priyadarshi I. Puljak W. Rhode M. Ribó J. Rico C. Righi A. Rugliancich N. Sahakyan T. Saito S. Sakurai K. Satalecka F. G. Sat Japanese MAGIC Group: Institute for Cosmic Ray Research (ICRR) The University of Tokyo Kashiwa 277-8582 Chiba Japan Instituto de Astrofísica de Canarias and Departamento de Astrofísica Universidad de La Laguna E-38200 La Laguna Tenerife Spain National Institute for Astrophysics (INAF) I-00136 Rome Italy Università di Udine and INFN Trieste I-33100 Udine Italy Max-Planck-Institut für Physik D-80805 München Germany Università di Padova and INFN I-35131 Padova Italy Institut de Física d’Altes Energies (IFAE) The Barcelona Institute of Science and Technology (BIST) E-08193 Bellaterra (Barcelona) Spain Technische Universität Dortmund D-44221 Dortmund Germany Croatian MAGIC Group: University of Zagreb Faculty of Electrical Engineering and Computing (FER) 10000 Zagreb Croatia IPARCOS Institute and EMFTEL Department Universidad Complutense de Madrid E-28040 Madrid Spain Centro Brasileiro de Pesquisas Físicas (CBPF) 22290-180 URCA Rio de Janeiro (RJ) Brazil University of Lodz Faculty of Physics and Applied Informatics Department of Astrophysics 90-236 Lodz Poland Instituto de Astrofísica de Andalucía-CSIC Glorieta de la Astronomía s/n 18008 Granada Spain Deutsches Elektronen-Synchrotron (DESY) D-15738 Zeuthen Germany ETH Zürich CH-8093 Zürich Switzerland Università di Pisa and INFN Pisa I-56126 Pisa Italy Universitat de Barcelona ICCUB IEEC-UB E-08028 Barcelona Spain Armenian MAGIC Group: A. Alikhanyan National Science Laboratory 0036 Yerevan Armenia Centro de Investigaciones Energéticas Medioambientales y Tecnológicas E-28040 Madrid Spain Department for Physics and Technology University of Bergen Norway INFN MAGIC Group: INFN Sezione di Catania and Dipartimento di Fisica e Astronomia University of Catania I-95123 Catania Italy INFN MAGIC Group: INFN Sezione di Torino and Università degli Studi di Torino I-10125 Torino Italy INFN MAGIC Group: INFN Sezione di Bari and Dipartimento Interateneo di Fisica dell’Università e del Politecnico di Bari I-70125 Bari Italy

Linelike features in TeV γ rays constitute a “smoking gun” for TeV-scale particle dark matter and new physics. Probing the Galactic Center region with ground-based Cherenkov telescopes enables the search for TeV spectral features in immediate association with a dense dark matter reservoir at a sensitivity out of reach for satellite γ-ray detectors, and direct detection and collider experiments. We report on 223 hours of observations of the Galactic Center region with the MAGIC stereoscopic telescope system reaching γ-ray energies up to 100 TeV. We improved the sensitivity to spectral lines at high energies using large-zenith-angle observations and a novel background modeling method within a maximum-likelihood analysis in the energy domain. No linelike spectral feature is found in our analysis. Therefore, we constrain the cross section for dark matter annihilation into two photons to ⟨σv⟩≲5×10−28 cm3 s−1 at 1 TeV and ⟨σv⟩≲1×10−25 cm3 s−1 at 100 TeV, achieving the best limits to date for a dark matter mass above 20 TeV and a cuspy dark matter profile at the Galactic Center. Finally, we use the derived limits for both cuspy and cored dark matter profiles to constrain supersymmetric wino models.

关键词： Dark matter Gamma ray astronomy Particle dark matter Milky Way Cosmic ray & astroparticle detectors Cosmic rays & astroparticles Electromagnetic radiation astronomy Telescopes

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Galactic transient sources with the Cherenkov Telescope Array Observatory

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Monthly Notices of the Royal Astronomical Society 2025年第1期540卷 205–238页

作者： Abe, K Abe, S Abhir, J Abhishek, A Acero, F Acharyya, A Adam, R Aguasca-Cabot, A Agudo, I Aguirre-Santaella, A Alfaro, J Alfaro, R Alvarez-Crespo, N Alves Batista, R Amans, J-P Amato, E Ambrosi, G Ambrosino, F Angüner, E O Antonelli, L A Aramo, C Arcaro, C Arnesen, T T H Asano, K Ascasibar, Y Aschersleben, J Ashkar, H Augusto Stuani, L Baack, D Backes, M Balazs, C Balbo, M Baquero Larriva, A Barbosa Martins, V Barres de Almeida, U Barrio, J A Barrios-Jiménez, L Batković, I Batzofin, R Baxter, J Becerra González, J Becker Tjus, J Belmont, R Benbow, W Bernete, J Bernlöhr, K Berti, A Bertucci, B Beshley, V Bhattacharjee, P Bhattacharyya, S Bigongiari, C Bissaldi, E Blanch, O Blazek, J Bocchino, F Boisson, C Bolmont, J Bonnoli, G Bonollo, A Bordas, P Bosnjak, Z Bottacini, E Böttcher, M Bradascio, F Bronzini, E Brown, A M Brunelli, G Bulgarelli, A Burelli, I Burger-Scheidlin, C Burmistrov, L Burton, M Buscemi, M Cailleux, J Campoy-Ordaz, A Cantlay, B K Capasso, G Caproni, A Capuzzo-Dolcetta, R Caraveo, P Caroff, S Carosi, A Carosi, R Carquin, E Carrasco, M-S Cascone, E Cassol, F Castaldini, L Castrejon, N Castro-Tirado, A J Cerasole, D Ceribella, G Cerruti, M Chadwick, P M Chaty, S Chen, A W Chernyakova, M Chiavassa, A Chudoba, J Chytka, L Cicciari, G M Cifuentes, A Coimbra Araujo, C H Colapietro, M Conforti, V Contreras, J L Cortina, J Costa, A Costantini, H Cotter, G Cristofari, P Cuevas, O Curtis-Ginsberg, Z D’Aì, A D’Amico, G D’Ammando, F Dai, S Dazzi, F de Bony de Lavergne, M De Caprio, V De Cesare, G De Frondat Laadim, F de Gouveia Dal Pino, E M De Lotto, B De Lucia, M de Martino, D de Menezes, R de Naurois, M de Ona Wilhelmi, E de Souza, V del Peral, L del Valle, M V Delgado, C Dell’aiera, M Della Valle, M della Volpe, D Depaoli, D Devin, J Di Girolamo, T Di Piano, A Di Pierro, F Di Tria, R Di Venere, L Diebold, S Dignam, C Dima, R Dinesh, A Djuvsland, J Dominik, R M Dominis Prester, D Donini, A Dorner, D Dörner, J Doro, M Dubos, C Ducci, L Dwarkadas, V V Ebr, J Eckner, C Egberts, K Einecke, S Elsässer, D Emery Department of Physics Tokai University 4-1-1 Kita-Kaname Hiratsuka Kanagawa 259-1292 Japan Institute for Cosmic Ray Research University of Tokyo 5-1-5 Kashiwa-no-ha Kashiwa Chiba 277-8582 Japan ETH Zürich Institute for Particle Physics and Astrophysics Otto-Stern-Weg 5 CH-8093 Zürich Switzerland INFN and Università degli Studi di Siena Dipartimento di Scienze Fisiche della Terra e dell’Ambiente (DSFTA) Sezione di Fisica Via Roma 56 I-53100 Siena Italy Université Paris-Saclay Université Paris Cité CEA CNRS AIM F-91191 Gif-sur-Yvette Cedex France FSLAC IRL 2009 CNRS/IAC E-38205 La Laguna Tenerife Spain University of Alabama Tuscaloosa Department of Physics and Astronomy Gallalee Hall Box 870324 Tuscaloosa AL 35487-0324 USA Université Côte d’Azur Observatoire de la Côte d’Azur CNRS Laboratoire Lagrange UF 06304 Nice France Laboratoire Leprince-Ringuet CNRS/IN2P3 École Polytechnique Institut Polytechnique de Paris F-91120 Palaiseau France Departament de Física Quàntica i Astrofísica Institut de Ciències del Cosmos Universitat de Barcelona IEEC-UB Martí i Franquès 1 E-08028 Barcelona Spain Instituto de Astrofísica de Andalucía-CSIC Glorieta de la Astronomía s/n E-18008 Granada Spain Institute for Computational Cosmology and Department of Physics Durham University South Road Durham DH1 3LE UK Pontificia Universidad Católica de Chile Av. Libertador Bernardo O’Higgins 340 8331150 Santiago Chile Universidad Nacional Autónoma de México Delegación Coyoacán 04510 Ciudad de México Mexico IPARCOS-UCM Instituto de Física de Partículas y del Cosmos and EMFTEL Department Universidad Complutense de Madrid E-28040 Madrid Spain Instituto de Física Teórica UAM/CSIC and Departamento de Física Teórica Universidad Autónoma de Madrid c/ Nicolás Cabrera 13-15 Campus de Cantoblanco UAM E-28049 Madrid Spain LUTH GEPI and LERMA Observatoire de Paris Université PSL Université Paris Cité CNRS 5 place Jules Janssen F-92190 Meudon France INAF – Osservatorio

A wide variety of Galactic sources show transient emission at soft and hard X-ray energies: low- and high-mass X-ray binaries containing compact objects, isolated neutron stars exhibiting extreme variability as magnetars as well as pulsar-wind nebulae. Although most of them can show emission up to MeV and/or GeV energies, many have not yet been detected in the TeV domain by Imaging Atmospheric Cherenkov Telescopes. In this paper, we explore the feasibility of detecting new Galactic transients with the Cherenkov Telescope Array Observatory (CTAO) and the prospects for studying them with Target of Opportunity observations. We show that CTAO will likely detect new sources in the TeV regime, such as the massive microquasars in the Cygnus region, low-mass X-ray binaries with low-viewing angle, flaring emission from the Crab pulsar-wind nebula or other novae explosions, among others. Since some of these sources could also exhibit emission at larger time-scales, we additionally test their detectability at longer exposures. We finally discuss the multiwavelength synergies with other instruments and large astronomical facilities.

关键词： binaries: general stars: magnetars novae cataclysmic variables pulsars: general gamma-rays: general

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Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

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Nature communications 2025年第1期16卷 4235-4235页

作者： Cecilia Anza-Ramirez J. Jaime Miranda Benedetta Armocida Jorge César Correia Harriette Gillian Christine Van Spall David Beran Amirali Aali Kalkidan Hassen Abate Semagn Mekonnen Abate Cristiana Abbafati Mohsen Abbasi-Kangevari Zeinab Abbasi-Kangevari Zahra Aryan Sina Azadnajafabad Mohammadreza Azangou-Khyavy Seyyed-Hadi Ghamari Mohammad Keykhaei Javad Khanali Sara Momtazmanesh Fateme Montazeri Shayan Rahmani Mohammad-Mahdi Rashidi Nazila Rezaei Negar Rezaei Sahar Saeedi Moghaddam Hossein Hassanian-Moghaddam Ali-Asghar Kolahi Ali Nikoobar Hedayat Abbastabar Ahmed M. Abdel-Azeem Michael Abdelmasseh Juan Sanabria Sherief Abd-Elsalam Ahmed Abdelwahab Gholamreza Abdoli Mohammad Abdollahi Meriem Abdoun Deldar Morad Abdulah Abu Yousuf Md Abdullah Ame Mehadi Abdurehman Getachew Abebe Aidin Abedi Chirag P. Doshi Vida Abedi Hassan Abidi Richard Gyan Aboagye Hassan Abolhassani Nima Rezaei Lucas Guimarães Abreu Michael R. M. Abrigo Yonas Derso Abtew Hiwa Abubaker Ali Eman Abu-Gharbieh Hiba Jawdat Barqawi Rabih Halwani Maha Mohamed Saber-Ayad Iman M. Talaat Ahmed Abu-Zaid Manfred Mario Kokou Accrombessi Juan Manuel Acuna Denberu Eshetie Adane Tigist Demssew Adane Isaac Yeboah Addo Giovanni Addolorato Oluwafemi Atanda Adeagbo Victor Adekanmbi Miracle Ayomikun Adesina Isaac Iyinoluwa Olufadewa Olatunji O. Adetokunboh Daniel Adedayo Adeyinka Qorinah Estiningtyas Sakilah Adnani Aanuoluwapo Adeyimika Afolabi Olayinka Stephen Ilesanmi Muhammad Sohail Afzal Saira Afzal Gina Agarwal Prerna Agarwal Pradyumna Agasthi Anurag Agrawal Marcela Agudelo-Botero Adolfo Martinez-Valle Bright Opoku Ahinkorah Aqeel Ahmad Sajjad Ahmad Sohail Ahmad Tauseef Ahmad Ali Ahmadi Siamak Sabour Keivan Ahmadi Sanjay Basu Sepideh Ahmadi Ali Ahmed Shaun Wen Huey Lee Ayman Ahmed Haroon Ahmed Jivan Qasim Ahmed Gahin Abdulraheem Tayib Yahya Yahya Luai A. Ahmed Iffat Elbarazi Syed Mahboob Shah Janardhana P. Aithala Marjan Ajami Budi Aji Hossein Akbarialiabad Yibeltal Akelew Meisam Akhlaghdoust Elham Jamshidi Addis Aklilu Azene Tesfaye Melat Woldemariam Maxwell Ak CRONICAS Center of Excellence in Chronic Diseases Universidad Peruana Cayetano Heredia Lima Peru School of Medicine Universidad Peruana Cayetano Heredia Lima Peru Sydney School of Public Health Faculty of Medicine and Health University of Sydney Sydney NSW Australia Faculty of Epidemiology and Population Health London School of Hygiene & Tropical Medicine London UK Division of Tropical and Humanitarian Medicine University of Geneva Geneva Switzerland Department of Cardiovascular Endocrine-metabolic Diseases and Aging Istituto Superiore di Sanità Rome Italy Division of Endocrinology Diabetology Nutrition and Therapeutic Patient Education Department of Medicine Geneva University Hospitals Geneva Switzerland Department of Medicine and Department of Health Research Evidence and Impact McMaster University Hamilton ON Canada Research Institute of St. Joe’s Hamilton ON Canada Population Health Research Institute Hamilton Canada Geneva University Hospitals Geneva Switzerland Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran Department of Nutrition and Dietetics Jimma University Jimma Ethiopia Anesthesiology Department Dilla University Addis Ababa Ethiopia Department of Juridical and Economic Studies La Sapienza University Rome Italy Non-Communicable Diseases Research Center Tehran University of Medical Sciences Tehran Iran Social Determinants of Health Research Center Shahid Beheshti University of Medical Sciences Tehran Iran Brigham and Women’s Hospital Harvard University Boston MA USA Students’ Scientific Research Center (SSRC) Tehran University of Medical Sciences Tehran Iran School of Medicine Tehran University of Medical Sciences Tehran Iran School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran Endocrinology and Metabolism Research Institute Tehran University of Medical Sciences Tehran Iran Chapter of Addiction Medicine University of Sydney Sydney NSW Australia Advanced Diagnostic and Intervent

Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands. This study examines the burden of conditions requiring acute versus chronic care, including sequelae. Conditions and sequelae from the Global Burden of Diseases Study 2019 were classified into acute or chronic care categories. Data were analysed by age, sex, and socio-demographic index, presenting total numbers and contributions to burden metrics such as Disability-Adjusted Life Years (DALYs), Years Lived with Disability (YLD), and Years of Life Lost (YLL). Approximately 68% of DALYs were attributed to chronic care, while 27% were due to acute care. Chronic care needs increased with age, representing 86% of YLDs and 71% of YLLs, and accounting for 93% of YLDs from sequelae. These findings highlight that chronic care needs far exceed acute care needs globally, necessitating health systems to adapt accordingly. © 2025. The Author(s).

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Author Correction: The high-dimensional space of human diseases built from diagnosis records and mapped to genetic loci

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Nature computational science 2023年第7期3卷 658页

作者： Gengjie Jia Yu Li Xue Zhong Kanix Wang Milton Pividori Rabab Alomairy Aniello Esposito Hatem Ltaief Chikashi Terao Masato Akiyama Koichi Matsuda David E Keyes Hae Kyung Im Takashi Gojobori Yoichiro Kamatani Michiaki Kubo Nancy J Cox James Evans Xin Gao Andrey Rzhetsky Shenzhen Branch Guangdong Laboratory of Lingnan Modern Agriculture Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural Sciences Shenzhen China. jiagengjie@***. Computational Bioscience Research Center King Abdullah University of Science and Technology Thuwal Saudi Arabia. Computer Science Program Computer Electrical and Mathematical Sciences and Engineering Division King Abdullah University of Science and Technology Thuwal Saudi Arabia. Department of Computer Science and Engineering The Chinese University of Hong Kong Hong Kong People's Republic of China. Department of Medicine and Vanderbilt Genetics Institute Vanderbilt University Medical Center Nashville TN US. Department of Medicine Institute of Genomics and Systems Biology Committee on Genomics Genetics and Systems Biology University of Chicago Chicago IL US. Department of Operations Business Analytics and Information Systems University of Cincinnati Cincinnati OH US. Department of Systems Pharmacology and Translational Therapeutics Perelman School of Medicine University of Pennsylvania Philadelphia PA US. Extreme Computing Research Center Computer Electrical and Mathematical Sciences and Engineering Division King Abdullah University of Science and Technology Thuwal Saudi Arabia. College of Computer Science and Engineering University of Jeddah Jeddah Saudi Arabia. HPE HPC/AI EMEA Research Laboratory Bristol UK. RIKEN Center for Integrative Medical Sciences Yokohama Japan. Clinical Research Center Shizuoka General Hospital Shizuoka Japan. Department of Applied Genetics The School of Pharmaceutical Sciences University of Shizuoka Shizuoka Japan. Department of Ophthalmology Graduate School of Medical Sciences Kyushu University Fukuoka Japan. Department of Computational Biology and Medical Sciences Graduate School of Frontier Sciences The University of Tokyo Tokyo Japan. Biological and Environmenta

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Search for Continuous Gravitational Waves from Known Pulsars in the First Part of the Fourth LIGO-Virgo-KAGRA Observing Run

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Astrophysical Journal 2025年第2期983卷 99-99页

作者： Abac, A.G. Abbott, R. Abouelfettouh, I. Acernese, F. Ackley, K. Adhicary, S. Adhikari, N. Adhikari, R.X. Adkins, V.K. Agarwal, D. Agathos, M. Aghaei Abchouyeh, M. Aguiar, O.D. Aguilar, I. Aiello, L. Ain, A. Ajith, P. Akutsu, T. Albanesi, S. Alfaidi, R.A. Al-Jodah, A. Alléné, C. Allocca, A. Al-Shammari, S. Altin, P.A. Alvarez-Lopez, S. Amato, A. Amez-Droz, L. Amorosi, A. Amra, C. Ananyeva, A. Anderson, S.B. Anderson, W.G. Andia, M. Ando, M. Andrade, T. Andres, N. Andrés-Carcasona, M. Andrić, T. Anglin, J. Ansoldi, S. Antelis, J.M. Antier, S. Aoumi, M. Appavuravther, E.Z. Appert, S. Apple, S.K. Arai, K. Araya, A. Araya, M.C. Areeda, J.S. Argianas, L. Aritomi, N. Armato, F. Arnaud, N. Arogeti, M. Aronson, S.M. Ashton, G. Aso, Y. Assiduo, M. Assis de Souza Melo, S. Aston, S.M. Astone, P. Attadio, F. Aubin, F. AultONeal, K. Avallone, G. Babak, S. Badaracco, F. Badger, C. Bae, S. Bagnasco, S. Bagui, E. Baier, J.G. Baiotti, L. Bajpai, R. Baka, T. Ball, M. Ballardin, G. Ballmer, S.W. Banagiri, S. Banerjee, B. Bankar, D. Baral, P. Barayoga, J.C. Barish, B.C. Barker, D. Barneo, P. Barone, F. Barr, B. Barsotti, L. Barsuglia, M. Barta, D. Bartoletti, A.M. Barton, M.A. Bartos, I. Basak, S. Basalaev, A. Bassiri, R. Basti, A. Bates, D.E. Bawaj, M. Baxi, P. Bayley, J.C. Baylor, A.C. Baynard, P.A. Bazzan, M. Bedakihale, V.M. Beirnaert, F. Bejger, M. Belardinelli, D. Bell, A.S. Benedetto, V. Benoit, W. Bentley, J.D. Ben Yaala, M. Bera, S. Berbel, M. Bergamin, F. Berger, B.K. Bernuzzi, S. Beroiz, M. Bersanetti, D. Bertolini, A. Betzwieser, J. Beveridge, D. Bevins, N. Bhandare, R. Bhardwaj, U. Bhatt, R. Bhattacharjee, D. Bhaumik, S. Bhowmick, S. Bianchi, A. Bilenko, I.A. Billingsley, G. Binetti, A. Bini, S. Birnholtz, O. Biscoveanu, S. Bisht, A. Bitossi, M. Bizouard, M.-A. Blackburn, J.K. Blagg, L.A. Blair, C.D. Blair, D.G. Bobba, F. Bode, N. Boileau, G. Boldrini, M. Bolingbroke, G.N. Bolliand, A. Bonavena, L.D. Bondarescu, R. Bondu, F. Bonilla, E. Bonilla, M.S. Bonino, A. Bonnand, R. Booker, P. Borchers, A. Boschi, V. Bose, S. Boss Max Planck Institute for Gravitational Physics (Albert Einstein Institute) Potsdam D-14476 Germany LIGO Laboratory California Institute of Technology Pasadena 91125 CA United States LIGO Hanford Observatory Richland 99352 WA United States Dipartimento di Farmacia Università di Salerno Fisciano Salerno I-84084 Italy INFN Sezione di Napoli Napoli I-80126 Italy University of Warwick Coventry CV 47AL United Kingdom The Pennsylvania State University University Park 16802 PA United States University of Wisconsin-Milwaukee Milwaukee 53201 WI United States Louisiana State University Baton Rouge 70803 LA United States Université Catholique de Louvain Louvain-la-Neuve B-1348 Belgium Inter-University Centre for Astronomy and Astrophysics Pune 411007 India Queen Mary University of London London E1 4NS United Kingdom Department of Physics and Astronomy Sejong University 209 Neungdong-ro Gwangjin-gu Seoul 143-747 South Korea Instituto Nacional de Pesquisas Espaciais São José dos Campos São Paulo 12227-010 Brazil Stanford University Stanford 94305 CA United States Università di Roma Tor Vergata Roma I-00133 Italy INFN Sezione di Roma Tor Vergata Roma I-00133 Italy Cardiff University Cardiff CF24 3AA United Kingdom Universiteit Antwerpen Antwerpen 2000 Belgium International Centre for Theoretical Sciences Tata Institute of Fundamental Research Bengaluru 560089 India Gravitational Wave Science Project National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka City Tokyo 181-8588 Japan Advanced Technology Center National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka City Tokyo 181-8588 Japan INFN Sezione di Torino Torino I-10125 Italy Theoretisch-Physikalisches Institut Friedrich-Schiller-Universität Jena Jena D-07743 Germany Dipartimento di Fisica Università degli Studi di Torino Torino I-10125 Italy SUPA University of Glasgow Glasgow G12 8QQ United Kingdom OzGrav University of Western Australia Crawley 6009 WA

Continuous gravitational waves (CWs) emission from neutron stars carries information about their internal structure and equation of state, and it can provide tests of general relativity. We present a search for CWs from a set of 45 known pulsars in the first part of the fourth LIGO-Virgo-KAGRA observing run, known as O4a. We conducted a targeted search for each pulsar using three independent analysis methods considering single-harmonic and dual-harmonic emission models. We find no evidence of a CW signal in O4a data for both models and set upper limits on the signal amplitude and on the ellipticity, which quantifies the asymmetry in the neutron star mass distribution. For the single-harmonic emission model, 29 targets have the upper limit on the amplitude below the theoretical spin-down limit. The lowest upper limit on the amplitude is 6.4 × 10^-27 for the young energetic pulsar J0537-6910, while the lowest constraint on the ellipticity is 8.8 × 10^-9 for the bright nearby millisecond pulsar J0437-4715. Additionally, for a subset of 16 targets, we performed a narrowband search that is more robust regarding the emission model, with no evidence of a signal. We also found no evidence of nonstandard polarizations as predicted by the Brans-Dicke theory. © 2025. The Author(s). Published by the American Astronomical Society.

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26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3 Antwerp, Belgium. 15-20 July 2017 Abstracts

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BMC NEUROSCIENCE 2017年第SUPPL 1期18卷 95-176页

作者： [Anonymous] Department of Neuroscience Yale University New Haven CT 06520 USA Department Physiology & Pharmacology SUNY Downstate Brooklyn NY 11203 USA NYU School of Engineering 6 MetroTech Center Brooklyn NY 11201 USA Departament de Matemàtica Aplicada Universitat Politècnica de Catalunya Barcelona 08028 Spain Institut de Neurobiologie de la Méditerrannée (INMED) INSERM UMR901 Aix-Marseille Univ Marseille France Center of Neural Science New York University New York NY USA Aix-Marseille Univ INSERM INS Inst Neurosci Syst Marseille France Laboratoire de Physique Théorique et Modélisation CNRS UMR 8089 Université de Cergy-Pontoise 95300 Cergy-Pontoise Cedex France Department of Mathematics and Computer Science ENSAT Abdelmalek Essaadi’s University Tangier Morocco Laboratory of Natural Computation Department of Information and Electrical Engineering and Applied Mathematics University of Salerno 84084 Fisciano SA Italy Department of Medicine University of Salerno 84083 Lancusi SA Italy Dipartimento di Fisica Università degli Studi Aldo Moro Bari and INFN Sezione Di Bari Italy Data Analysis Department Ghent University Ghent Belgium Coma Science Group University of Liège Liège Belgium Cruces Hospital and Ikerbasque Research Center Bilbao Spain BIOtech Department of Industrial Engineering University of Trento and IRCS-PAT FBK 38010 Trento Italy Department of Data Analysis Ghent University Ghent 9000 Belgium The Wellcome Trust Centre for Neuroimaging University College London London WC1N 3BG UK Department of Electronic Engineering NED University of Engineering and Technology Karachi Pakistan Blue Brain Project École Polytechnique Fédérale de Lausanne Lausanne Switzerland Departement of Mathematics Swansea University Swansea Wales UK Laboratory for Topology and Neuroscience at the Brain Mind Institute École polytechnique fédérale de Lausanne Lausanne Switzerland Institute of Mathematics University of Aberdeen Aberdeen Scotland UK Department of Integrativ

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26th Annual Computational Neuroscience Meeting (CNS*2017) of the Organization for Computational Neuroscience Antwerp, Belgium, July 15-20, 2017

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BMC NEUROSCIENCE 2017年第SUPPL 1期18卷 59-59页

作者： [Anonymous] Indiana University Purdue University Indianapolis Indianapolis IN 46032 USA Stark Neurosciences Research Institute Indiana University School of Medicine Indianapolis IN 46032 USA Department of Mathematics East Carolina University Greenville NC 27858 USA Jülich Supercomputing Centre Forschungszentrum Jülich 52425 Jülich Germany Future Systems Swiss National Supercomputing Centre 8092 Zurich Switzerland User Engagement and Support Swiss National Supercomputing Centre 6900 Lugano Switzerland Institut de Neurosciences des Systèmes Aix Marseille Univ 13005 Marseille France Simulation Lab Neuroscience Forschungszentrum Jülich Jülich Germany Department of Experimental Psychology Ghent University 9000 Ghent Belgium Donders Center for Cognitive Neuroimaging Radboud University 6525HR Nijmegen The Netherlands Department of Electrical Computer and Energy Engineering University of Colorado Boulder CO 80309 USA Department of Neurosurgery Johns Hopkins School of Medicine Baltimore MD 21287 USA Department of Neurology Johns Hopkins School of Medicine Baltimore MD 21287 USA Department of Otolaryngology Johns Hopkins School of Medicine Baltimore MD 21287 USA INSERM U968 Paris France Sorbonne Universités UPMC University Paris 06 UMR_S 968 Institut de la Vision Paris France CNRS UMR_7210 Paris France Department of Computer Architecture and Technology University of Granada (CITIC) Granada Spain Sorbonne Universités UPMC Univ Paris 06 INSERM CNRS Institut de la Vision Paris France Department of Adaptive Machine Systems Osaka University Osaka Japan Department of Computer Science University of Cergy-Pontoise Cergy-Pontoise France Department of Physics and Astronomy College of Charleston Charleston SC 29424 USA School of Physics Faculty of Science University of Sydney Sydney NSW 2006 Australia Center of Excellence for Integrative Brain Function Australian Research Council Sydney Australia Max Planck Institute for Human Cognitive and Brain Sciences Saxony Lei

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FANTOM5 CAGE profiles of human and mouse samples

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Scientific Data 2017年第1期4卷 1-10页

作者： Noguchi, Shuhei Arakawa, Takahiro Fukuda, Shiro Furuno, Masaaki Hasegawa, Akira Hori, Fumi Ishikawa-Kato, Sachi Kaida, Kaoru Kaiho, Ai Kanamori-Katayama, Mutsumi Kawashima, Tsugumi Kojima, Miki Kubosaki, Atsutaka Manabe, Ri-Ichiroh Murata, Mitsuyoshi Nagao-Sato, Sayaka Nakazato, Kenichi Ninomiya, Noriko Nishiyori-Sueki, Hiromi Noma, Shohei Saijyo, Eri Saka, Akiko Sakai, Mizuho Simon, Christophe Suzuki, Naoko Tagami, Michihira Watanabe, Shoko Yoshida, Shigehiro Arner, Peter Axton, Richard A. Babina, Magda Kenneth Baillie, J. Barnett, Timothy C. Beckhouse, Anthony G. Blumenthal, Antje Bodega, Beatrice Bonetti, Alessandro Briggs, James Brombacher, Frank Carlisle, Ailsa J. Clevers, Hans C. Davis, Carrie A. Detmar, Michael Dohi, Taeko Edge, B. Albert S. Edinger, Matthias Ehrlund, Anna Ekwall, Karl Endoh, Mitsuhiro Enomoto, Hideki Eslami, Afsaneh Fagiolini, Michela Fairbairn, Lynsey Farach-Carson, Mary C. Faulkner, Geoffrey J. Ferrai, Carmelo Fisher, Malcolm E. Forrester, Lesley M. Fujita, Rie Furusawa, Jun-Ichi Geijtenbeek, Teunis B. Gingeras, Thomas Goldowitz, Daniel Guhl, Sven Guler, Reto Gustincich, Stefano Ha, Thomas J. Hamaguchi, Masahide Hara, Mitsuko Hasegawa, Yuki Herlyn, Meenhard Heutink, Peter Hitchens, Kelly J. Hume, David A. Ikawa, Tomokatsu Ishizu, Yuri Kai, Chieko Kawamoto, Hiroshi Kawamura, Yuki I. Kempfle, Judith S. Kenna, Tony J. Kere, Juha Khachigian, Levon M. Kitamura, Toshio Klein, Sarah Peter Klinken, S. Knox, Alan J. Kojima, Soichi Koseki, Haruhiko Koyasu, Shigeo Lee, Weonju Lennartsson, Andreas MacKay-Sim, Alan Mejhert, Niklas Mizuno, Yosuke Morikawa, Hiromasa Morimoto, Mitsuru Moro, Kazuyo Morris, Kelly J. Motohashi, Hozumi Mummery, Christine L. Nakachi, Yutaka Nakahara, Fumio Nakamura, Toshiyuki Nakamura, Yukio Nozaki, Tadasuke Ogishima, Soichi Ohkura, Naganari Ohno, Hiroshi Ohshima, Mitsuhiro Okada-Hatakeyama, Mariko Okazaki, Yasushi Orlando, Valerio Ovchinnikov, Dmitry A. Passier, Robert Patrikakis, Margaret Pombo, Ana Pradhan-Bhatt, Swati Qin, Xian-Yang Rehli, Michael Rizzu, Patrizia Roy, S Division of Genomic Technologies RIKEN Center for Life Science Technologies Yokohama Kanagawa 230-0045 Japan RIKEN Omics Science Center Yokohama Kanagawa 230-0045 Japan Department of Medicine Karolinska Institutet Stockholm 14186 Sweden Karolinska University Hospital Center for Metabolism and Endocrinology Stockholm 14186 Sweden Scottish Centre for Regenerative Medicine University of Edinburgh 5 Little France Drive Edinburgh EH164UU United Kingdom Department of Dermatology and Allergy Charite University Medicine Berlin Charitéplatz 1 Berlin 10117 Germany Roslin Institute and Royal School of Veterinary Studies University of Edinburgh Edinburgh EH259RG United Kingdom Australian Infectious Diseases Research Centre University of Queensland St Lucia 4072 QLD Australia School of Chemistry and Molecular Biosciences University of Queensland St Lucia 4072 QLD Australia Bio-Rad Laboratories Pty Ltd Hercules 94547 CA United States University of Queensland Diamantina Institute University of Queensland Woolloongabba 4102 QLD Australia IRCCS Fondazione Santa Lucia Via del Fosso di Fiorano 64 Rome 00143 Italy Australian Institute for Bioengineering and Nanotechnology University of Queensland Brisbane St Lucia 4072 QLD Australia Division of Immunology Institute of Infectious Diseases and Molecular Medicine University of Cape Town Anzio Road Observatory 7925 South Africa Immunology of Infectious Diseases Faculty of Health Sciences South African Medical Research Council University of Cape Town Anzio Road 7925 South Africa International Centre for Genetic Engineering and Biotechnology Cape Town Component Anzio Road 7925 South Africa Hubrecht Institute Royal Netherlands Academy of Arts and Sciences Uppsalalaan 8 3584 Netherlands University Medical Centre Utrecht Postbus 85500 Utrecht 3508 Netherlands Genomics Cold Spring Harbor Laboratory Cold Spring Harbor New York 11797 NY United States Institute of Pharmaceutical Sciences ETH Zurich Vladi

In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of Gene Expression) coupled with single-molecule sequencing. Approximately three thousands of samples, consisting of a variety of primary cells, tissues, cell lines, and time series samples during cell activation and development, were subjected to a uniform pipeline of CAGE data production. The analysis pipeline started by measuring RNA extracts to assess their quality, and continued to CAGE library production by using a robotic or a manual workflow, single molecule sequencing, and computational processing to generate frequencies of transcription initiation. Resulting data represents the consequence of transcriptional regulation in each analyzed state of mammalian cells. Non-overlapping peaks over the CAGE profiles, approximately 200,000 and 150,000 peaks for the human and mouse genomes, were identified and annotated to provide precise location of known promoters as well as novel ones, and to quantify their activities.

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Search for Gravitational Waves Emitted from SN 2023ixf

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The Astrophysical Journal 2025年第2期985卷 183-183页

作者： A. G. Abac R. Abbott I. Abouelfettouh F. Acernese K. Ackley S. Adhicary N. Adhikari R. X. Adhikari V. K. Adkins D. Agarwal M. Agathos M. Aghaei Abchouyeh O. D. Aguiar I. Aguilar L. Aiello A. Ain T. Akutsu S. Albanesi R. A. Alfaidi A. Al-Jodah C. Alléné A. Allocca S. Al-Shammari P. A. Altin S. Alvarez-Lopez A. Amato L. Amez-Droz A. Amorosi C. Amra A. Ananyeva S. B. Anderson W. G. Anderson M. Andia M. Ando T. Andrade N. Andres M. Andrés-Carcasona T. Andrić J. Anglin S. Ansoldi J. M. Antelis S. Antier M. Aoumi E. Z. Appavuravther S. Appert S. K. Apple K. Arai A. Araya M. C. Araya J. S. Areeda L. Argianas N. Aritomi F. Armato N. Arnaud M. Arogeti S. M. Aronson G. Ashton Y. Aso M. Assiduo S. Assis de Souza Melo S. M. Aston P. Astone F. Attadio F. Aubin K. AultONeal G. Avallone S. Babak F. Badaracco C. Badger S. Bae S. Bagnasco E. Bagui J. G. Baier L. Baiotti R. Bajpai T. Baka M. Ball G. Ballardin S. W. Ballmer S. Banagiri B. Banerjee D. Bankar P. Baral J. C. Barayoga B. C. Barish D. Barker P. Barneo F. Barone B. Barr L. Barsotti M. Barsuglia D. Barta A. M. Bartoletti M. A. Barton I. Bartos S. Basak A. Basalaev R. Bassiri A. Basti D. E. Bates M. Bawaj P. Baxi J. C. Bayley A. C. Baylor P. A. Baynard II M. Bazzan V. M. Bedakihale F. Beirnaert M. Bejger D. Belardinelli A. S. Bell V. Benedetto W. Benoit J. D. Bentley M. Ben Yaala S. Bera M. Berbel F. Bergamin B. K. Berger S. Bernuzzi M. Beroiz D. Bersanetti A. Bertolini J. Betzwieser D. Beveridge N. Bevins R. Bhandare U. Bhardwaj R. Bhatt D. Bhattacharjee S. Bhaumik S. Bhowmick A. Bianchi I. A. Bilenko G. Billingsley A. Binetti S. Bini O. Birnholtz S. Biscoveanu A. Bisht M. Bitossi M.-A. Bizouard J. K. Blackburn L. A. Blagg C. D. Blair D. G. Blair F. Bobba N. Bode G. Boileau M. Boldrini G. N. Bolingbroke A. Bolliand L. D. Bonavena R. Bondarescu F. Bondu E. Bonilla M. S. Bonilla A. Bonino R. Bonnand P. Booker A. Borchers V. Boschi S. Bose V. Bossilkov V. Boudart A. Boudon A. Bozzi C. Bradaschia P. R. Brady M. Braglia A. Branch M. Branchesi J. Brandt I. Braun M. Breschi T. B Max Planck Institute for Gravitational Physics (Albert Einstein Institute) D-14476 Potsdam Germany LIGO Laboratory California Institute of Technology Pasadena CA 91125 USA LIGO Hanford Observatory Richland WA 99352 USA Dipartimento di Farmacia Università di Salerno I-84084 Fisciano Salerno Italy INFN Sezione di Napoli I-80126 Napoli Italy University of Warwick Coventry CV4 7AL UK The Pennsylvania State University University Park PA 16802 USA University of Wisconsin-Milwaukee Milwaukee WI 53201 USA Louisiana State University Baton Rouge LA 70803 USA Université catholique de Louvain B-1348 Louvain-la-Neuve Belgium Inter-University Centre for Astronomy and Astrophysics Pune 411007 India Queen Mary University of London London E1 4NS UK Department of Physics and Astronomy Sejong University 209 Neungdong-ro Gwangjin-gu Seoul 143-747 Republic of Korea Instituto Nacional de Pesquisas Espaciais 12227-010 São José dos Campos São Paulo Brazil Stanford University Stanford CA 94305 USA Università di Roma Tor Vergata I-00133 Roma Italy INFN Sezione di Roma Tor Vergata I-00133 Roma Italy Cardiff University Cardiff CF24 3AA UK Universiteit Antwerpen 2000 Antwerpen Belgium Gravitational Wave Science Project National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka City Tokyo 181-8588 Japan Advanced Technology Center National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka City Tokyo 181-8588 Japan INFN Sezione di Torino I-10125 Torino Italy Theoretisch-Physikalisches Institut Friedrich-Schiller-Universität Jena D-07743 Jena Germany Dipartimento di Fisica Università degli Studi di Torino I-10125 Torino Italy SUPA University of Glasgow Glasgow G12 8QQ UK OzGrav University of Western Australia Crawley Western Australia 6009 Australia University Savoie Mont Blanc CNRS Laboratoire d’Annecy de Physique des Particules - IN2P3 F-74000 Annecy France Università di Napoli “Federico II ” I-80126 Napoli Italy OzGrav Australian National University C

We present the results of a search for gravitational-wave transients associated with core-collapse supernova SN 2023ixf, which was observed in the galaxy Messier 101 via optical emission on 2023 May 19, during the LIGO–Virgo–KAGRA 15th Engineering Run. We define a five-day on-source window during which an accompanying gravitational-wave signal may have occurred. No gravitational waves have been identified in data when at least two gravitational-wave observatories were operating, which covered ∼14% of this five-day window. We report the search detection efficiency for various possible gravitational-wave emission models. Considering the distance to M101 (6.7 Mpc), we derive constraints on the gravitational-wave emission mechanism of core-collapse supernovae across a broad frequency spectrum, ranging from 50 Hz to 2 kHz, where we assume the gravitational-wave emission occurred when coincident data are available in the on-source window. Considering an ellipsoid model for a rotating proto-neutron star, our search is sensitive to gravitational-wave energy 1 × 10⁻⁴ M_⊙c² and luminosity 2.6 × 10⁻⁴ M_⊙c² s⁻¹ for a source emitting at 82 Hz. These constraints are around an order of magnitude more stringent than those obtained so far with gravitational-wave data. The constraint on the ellipticity of the proto-neutron star that is formed is as low as 1.08, at frequencies above 1200 Hz, surpassing past results.

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