Matrix grammars are one of the first approaches ever proposed in regulated rewriting, prescribing that rules have to be applied in a certain order. In traditional regulated rewriting, the most interesting case shows u...
详细信息
One of the most promising applications of quantum networks is entanglement assisted sensing. The field of quantum metrology exploits quantum correlations to improve the precision bound for applications such as precisi...
详细信息
In the absence of a suspect or PoI the forensic aim is investigative, and the focus is one of discerning what candidate genotypes best explain the evidence. In traditional bulk systems, the list of candidate genotypes...
详细信息
In the absence of a suspect or PoI the forensic aim is investigative, and the focus is one of discerning what candidate genotypes best explain the evidence. In traditional bulk systems, the list of candidate genotypes may become vast if the sample contains DNA from many donors or the information from a minor contributor is swamped by that of major contributors, leading to lower evidential value for a true donor’s contribution and, as a result, possibly overlooked or inefficient investigative *** developments in single-cell analysis offer a way forward, by producing data capable of discriminating between genotypes. This is accomplished by first clustering single-cell data by similarity without reference to a known genotype. With good clustering it is reasonable to assume that the scEPGs in a cluster are of a single contributor. With that assumption we determine the probability of a cluster’s content given each possible genotype at each locus, which is then used to determine the posterior probability mass distribution for all genotypes by application of Bayes’ rule. A decision criterion is then applied such that the sum of the ranked probabilities of all genotypes falling in the set is at least . This is the credible genotype set and is the one used to inform database search criteria and, thus, investigative *** demonstrate the salience of single cell analysis by performance testing a set of 630 previously constructed admixtures containing up to 5 donors of balanced and unbalanced contributions. We use scEPGs that were generated by isolating single cells, employing a direct-to-PCR extraction treatment, amplifying STRs that are compliant with existing national databases and applying post-PCR treatments that elicit a detection limit of one DNA copy. We determined that, for these test data, 99.3% of the true genotypes are included in the 99.8% credible set, regardless of the number of donors that comprised the mixture. We also determined that the most proba
In magnetic confinement fusion devices, the equilibrium configuration of a plasma is determined by the balance between the hydrostatic pressure in the fluid and the magnetic forces generated by an array of external co...
详细信息
While numerous methods have been proposed for computing distances between probability distributions in Euclidean space, relatively little attention has been given to computing such distances for distributions on graph...
详细信息
Modeling the distribution of high dimensional data by a latent tree graphical model is a prevalent approach in multiple scientific domains. A common task is to infer the underlying tree structure, given only observati...
详细信息
Accurate and flexible representations of music data are paramount to addressing MIR tasks, yet many of the existing approaches are difficult to interpret or rigid in nature. This work introduces two new song represent...
详细信息
Although data diffusion embeddings are ubiquitous in unsupervised learning and have proven to be a viable technique for uncovering the underlying intrinsic geometry of data, diffusion embeddings are inherently limited...
详细信息
The manifold scattering transform is a deep feature extractor for data defined on a Riemannian manifold. It is one of the first examples of extending convolutional neural network-like operators to general manifolds. T...
详细信息
暂无评论