An efficient compositional framework is developed for simulation of CO2 storage in saline aquifers during a full-cycle injection, migration and post-migration processes. Essential trapping mechanisms, including struct...
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The maximal regularity property of discontinuous Galerkin methods for linear parabolic equations is used together with variational techniques to establish a priori and a posteriori error estimates of optimal order und...
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Motivation Phantom systems consisting of liposome suspensions are widely employed to investigate quantitative MRI parameters mimicking cellular membranes. The proper physical understanding of the measurement results, ...
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Motivation Phantom systems consisting of liposome suspensions are widely employed to investigate quantitative MRI parameters mimicking cellular membranes. The proper physical understanding of the measurement results, however, requires proper models for liposomes and their interaction with the surrounding water molecules. Molecular dynamics (MD) simulations allow for investigating the basic lipid-water interaction and determining quantitative MR parameters such as R1 = 1/T1. Here, we present an MD-based approach for the theoretical prediction of R1, the dependence of R1 on water concentration and the magnetization exchange between lipids and interacting water layer in lipids and lipid mixtures. Moreover, a new parameter is introduced which quantitatively measures the amount of hydration water based on conventional spoiled gradient echo MR acquisitions. Methods Molecular dynamics simulations were performed to determine the native R1 rates in three lipids and their interacting water pools. Employing a three-pool exchange model between lipid, hydration water and free water, the hydration water fraction, fHW, as a new parameter as well as the magnetization transfer rate between hydration water and lipids, kHW,L, were quantitatively determined, from which the water concentration dependence of R1 was predicted for all liposome systems investigated. Results Both fHW and kHW,L were determined quantitatively from spoiled gradient echo data by taking the MD-determined relaxation rates into account. Liposome systems behaved similarly, apart from PLPC which showed both lower hydration water fraction and lower exchange rate. The extracted parameters accurately predicted the measured water fraction-dependent R1 rates. Conclusion Hydration water fraction and magnetisation transfer between lipids and water can be determined by a combination of spoiled gradient echo acquisitions and MD-derived relaxation rates. The parameters enable a theoretical understanding of MR parameters in lip
In the framework of rough sets, incremental algorithms can effectively reduce repetitive computations for dynamic datasets by discovering the update principles of relevant *** the variations in attribute sets, increme...
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In this research, we investigate the use of Reinforcement Learning (RL) for an effective and robust solution for exploring unknown and indoor environments and reconstructing their maps. We benefit from a Simultaneous ...
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This article examines the use of count data models to predict the number of tourists visiting Thailand's national parks. The dataset, encompassing observations from 2016 to 2022 across 146 national parks, exhibits...
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Foam bed flotation processes are common in the poly metallic, potash and food industries. A worker who visually assesses the condition of the foam bed controls the process. This reduces process control and product qua...
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Suppose that we are given a formal power series of many variables with coefficients in R (or ℂ) and we want to compute its n-th (multiplicative) root. As can be expected coefficients of the root have to satisfy a syst...
This paper aims at a deep reinforcement learning (DRL) controller for fast (< 1.5s) manipulation of a flexible tool (i.e., whip) to hit a target in 3D space. The controller consists of a DRL algorithm for optimizin...
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ISBN:
(数字)9798331516857
ISBN:
(纸本)9798331516864
This paper aims at a deep reinforcement learning (DRL) controller for fast (< 1.5s) manipulation of a flexible tool (i.e., whip) to hit a target in 3D space. The controller consists of a DRL algorithm for optimizing joint motions, and a proportional-derivative (PD) mechanism for tracking the optimized motions. Their objective is to minimize the distance between the whip-end-tip and the target. The proposed controller was validated in a 7-DOF robot arm by comparing four DRL algorithms in the physical simulator MuJoCo. It shows that the proximal policy optimization (PPO) outperforms others by obtaining the maximum average reward. Notably, PPO can still effectively interact with the environment under sparse or even unrewarding conditions, making it a robust choice for complex and dynamic tasks. Our work provides preliminary knowledge of DRL applications to fast robotic arm control in flexible object manipulation.
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