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Optical Terahertz Science and Technology, OTST 2007

作者： Corridon, Peter M. Claudio, David Wilke, Ingrid Department of Biomedical Engineering Rensselaer Polytechnic Institute Troy NY 12180-3590 United States Department of Industrial and Manufacturing Engineering Pennsylvania State University University Park PA 16803-3598 United States Department of Physics Applied Physics and Astronomy Rensselaer Polytechnic Institute Troy NY 12180-3590 United States

Thus far studies reported on the interactions of terahertz radiation and skin have centered on the dermal layers. However, we determined that there is a need to account for the effects from hair structures. © 200... 详细信息

ISBN: (纸本)1557528373

关键词： Electromagnetic wave emission

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Analysis of patient bed positioning in SPECT-CT imaging for dedicated mammotomography

Analysis of patient bed positioning in SPECT-CT imaging for ...

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Medical Imaging 2007: physics of Medical Imaging

作者： Perez, Kristy L. Madhav, Priti Crotty, Dominic J. Tornai, Martin P. Medical Physics Graduate Program Duke University Medical Center Durham NC 27710 Department of Radiology Duke University Medical Center Durham NC 27710 Department of Biomedical Engineering Duke University Durham NC 27708

ISBN: (纸本)081946628X

Patient positioning on a bed is an integral part of accurate imaging for dedicated 3D breast imaging. For both dedicated breast SPECT (single photon emission computed tomography) and breast CT (computed tomography or computed mammotomography, CmT) which are under development in our lab, maximum access to the breast in the imaging system's field of view is required to obtain the largest imaged breast volume. Accurate bed positioning will be necessary as it may be integrated with a guided biopsy apparatus. Thus, a patient bed with flexible 3D positioning capability is being integrated into the various independent and hybrid 3D imaging systems. The customized bed has both manual and computer controlled positioning capability, and the accuracy and reproducibility of the system are being characterized. Computer controlled positioning and feedback provide seemingly reproducible results. However, gross movements may vary in their accuracy to the given input position. While linear with slopes near 1.0 and intercepts near 0.0cm, lateral (Y) movement translates less than the input amount, while axial (X) movement translates farther than the input amount. Vertical (Z) directional movement follows a quadratic shift with a small dc component with or without added weight on the table. A variety of patient imaging conditions along with x-ray image data are evaluated to demonstrate the reproducibility of positioning accuracy. Individual directional repositioning accuracy is found to be better than multiple, combined directional repositioning accuracy. Imaging results indicate a reproducibility (error) of less than 1mm, which may be suitable for SPECT imaging but perhaps not for higher resolution dedicated breast CT. However, for the independent SPECT system, bed motion is not necessary because the detector's line of sight can already acquire data at the chest wall.

关键词： Medical imaging

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Method of Calibrating Response Statistics for ML Estimation of 3D Interaction Position in a Thick-Detector Gamma Camera

Method of Calibrating Response Statistics for ML Estimation ...

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2007 IEEE Nuclear Science Symposium Conference, vol.11

作者： William C. J. Hunter Harrison H. Barrett Lars R. Furenlid Stephen K. Moore Department of Physics and is now appointed in the Department of Radiology University of Arizona Tucson AZ USA Department of Radiology the College of Optical Sciences the Applied Mathematics Program and the Biomedical Engineering Program University of Arizona Tucson Tucson AZ USA Department of Radiology the College of Optical Sciences and the Biomedical Engineering Program University of Arizona Tucson Tucson AZ USA Biomedical Engineering Program University of Arizona Tucson Tucson AZ USA

High-energy photon detectors are often made thick in order to improve their photon-detection efficiency. To avoid issues of parallax and increased signal variance that result from random interaction depth, we must determine the 3D interaction position in the imaging detector. With this goal in mind, we examine a method of calibrating response statistics of a thick-detector gamma camera to produce a maximum- likelihood estimate of 3D interaction position. We parameterize the mean detector response as a function of 3D position and estimate the parameters by maximizing their likelihood given prior knowledge of the path-length distribution and a complete list of camera signals for an ensemble of gamma-ray interactions. Demonstrating this calibration method with simulated gamma-camera data, we show that the resulting calibration is accurate and can be used to produce unbiased estimates of 3D interaction position.

关键词： Statistics Maximum likelihood estimation Cameras Calibration Optical imaging Statistical distributions Maximum likelihood detection Gamma ray detection Gamma ray detectors Parameter estimation

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Scientific Session of the Physical Sciences Division of the Russian Academy of Sciences 'Methods of wave-based physics in neuroscience problems and applications' (31 October 2007)

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physics-Uspekhi 2008年第3期51卷

作者： V I Nekorkin B P Bezruchko V I Ponomarenko M D Prokhorov D A Smirnov P A Tass Institute of Applied Physics Russian Academy of Sciences Nizhnii Novgorod Russian Federation Department of Nano- and Biomedical Technologies N.G. Chernyshevskii Saratov State University Saratov Russian Federation Institute of Radio Engineering and Electronics Russian Academy of Sciences Saratov Branch Saratov Russian Federation Institute of Neurosciences and Biophysics - Medicine (INB-3) Research Center Juelich Juelich Germany

A scientific session of the Physical Sciences Division of the Russian Academy of Sciences (RAS) was held under the title 'Methods of wave-based physics in neuroscience problems and applications' on October 31, 2007 in the conference hall of the P N Lebedev Physical Institute, RAS. The following reports were presented at the session: (1) Nekorkin V I (Institute of applied physics, RAS, Nizhny Novgorod) 'Nonlinear oscillations and waves in neurodynamics'; (2) Bezruchko B P (department of Nano- and biomedical Technologies, Saratov State University, Saratov), Ponomarenko V I, Prokhorov M D, Smirnov D A (Saratov Branch of the Institute of Radioengineering and Electronics, RAS, Saratov), Tass P A (Juelich Research Center, Institute of Neuroscience and Biophysics 3-Medicine, Juelich, Germany) 'Modeling nonlinear oscillatory systems and diagnostics of coupling between them using chaotic time series analysis: applications in neurophysiology'. An abridged version of these reports is given below. • Nonlinear oscillations and waves in neurodynamics, V I Nekorkin physics-Uspekhi, 2008, Volume 51, Number 3, Pages 295–304 • Modeling nonlinear oscillatory systems and diagnostics of coupling between them using chaotic time series analysis: applications in neurophysiology, B P Bezruchko, V I Ponomarenko, M D Prokhorov, D A Smirnov and P A Tass physics-Uspekhi, 2008, Volume 51, Number 3, Pages 304–310

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Towards the simultaneous on-line estimation of the compliance and outflow resistance of the cerebrospinal fluid system 9

Towards the simultaneous on-line estimation of the complianc...

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2007 9th European Control Conference, ECC 2007

作者： Manchester, Ian R. Andersson, Kennet S. Eklund, Anders Shiriaev, Anton S. Department of Applied Physics and Electronics Umea University SE-901 87 Sweden Department of Radiation Sciences Umea University SE-901 87 Sweden Department of Engineering Cybernetics Norwegian University of Science and Technology TrondheimN-7491 Norway Department of Biomedical Engineering and Informatics Umea University Hospital SE-901 85 Sweden

ISBN: (纸本)9783952417386

Accurate estimates of the compliance and outflow resistance of the human cerebrospinal fluid system are important for diagnosis of a medical condition known as hydrocephalus. In this paper we design an observer which provides simultaneous on-line estimates of the outflow resistance and compliance, to our knowledge the first method to do so. It's performance is experimentally verified using the same apparatus used to perform actual patient diagnoses and a specially designed physical model of the human cerebrospinal fluid system. © 2007 EUCA.

关键词： Diagnosis

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Abstracts for the 6th Congress of Asian Sleep Research Society

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Sleep and Biological Rhythms 2009年第4期7卷 A1-A49页

作者： Seog Ju Kim In Kyoon Lyoo Yu-Jin Lee Do-Un Jeong Hirohiko Kanai Masanori Ookubo Atsushi Yoshimura Masako Okawa Noto Yamada Takeshi Munezawa Yoshitaka Kaneita Yoneatsu Osaki Hideyuki Kanda Tadahiro Ohtsu Masumi Minowa Kenji Suzuki Susumu Hijuchi Hiroyuki Suzuki Takashi Ohida Takashi Abe Yoko Komada Shoichi Asaoka Yuichi Inoue Jin-Seong Lee Sang-Yong Cho Deependra Kumar Hruda N. Mallick Velayudhan M. Kumar Mahesh K. Kaushik Akihiro Karashima Noiihiro Katayama Mitsuyuki Nakao Ravindra P. Nagendra Sathiamma Sulekha Sathyaprabha T. Narasappa Pradhan Nityanadan Bindu M. Kutty M. Nirmala P. N. Ravindra Basavaraj Ramappa Tubaki T. N. Sathyaprabha D. Sudhakar G. S. Lavekar C. R. Chandrashekar Kazuyoshi Kitaoka Mika Shimizu Sachiko Chikahisa Kazuo Yoshizaki Hiroyoshi Sei Jong-Won Kim Misa Takegami Shin Yamazaki Yasuaki Hayashino Rei Ono Koji Otani Miho Sekiguchi Shinichi Konno Shunichi Fukuhara Antonia J. Jakobson Paul Fitzgerald Russell Conduit Xin Shirley Li Siu Ping Joyce Lam Wai Man Mandy Yu Yun Kwok Wing Kazue Okamoto-Mizuno Koh Mizuno Mituaki Yamamoto Shuichiro Shirakawa Hirokazu Doi Mikako Kato Kazuyuki Shinohara Masako Tamaki Shiori Matsuda Katsuo Yamazaki Tadao Hori Keiko Ogawa Kazumi Takahashi Kunio Kitahama Katuo Yamazaki Yoshimasa Koyama Kohei Shioda Yugo Ueda Yukiko Nakamura Clara Inoue Kazushige Goto Sunao Uchida Yuko Morita Yoshiko Honda Tohru Kodama Mari Hagihara Toru Nakajima Masato Saito Yoshihiko Koga Shinichiro Tanaka Hiroshi Yamadera Madoka Takahara Sachiko Suwa Minoru Onozuka Sadao Sato Fumiharu Togo Taiki Komatsu Takeshi Mitani Jongbae Choi Bin Zhang Taeko Sasai Hiromi Mitsubayashi Mitsuhiro Ohtsu Isao Hasegawa Tatsuya Ishii Akira Komori Asami Suzuki Yue Nakahara Mitsuyasu Hiroki Mariko Nakauma Nobuo Someya Tomomasa Ochiai Shouhei Komori Rayleigh Ping-Ying Chiang Zai-Ting Yeh Seong T. Kim Seung H. Yoon Jeong S. Kwon Jong H. Choi Hyung J. Ahn Youngsoo Kim Bolortuya Yunren Lichao Chen Radhika Basheer Robert W. Mccarley Robert E. Strecker Makoto Honda Tetsuaki Arai Miyuki Fukazawa Yutaka Honda Kuniaki T Department of Psychiatry Gachon University of Medicine and Science Incheon Republic of Korea Department of Psychiatry Seoul National University Seoul Republic of Korea Department of Neuropsychiatry and Center for Sleep and Chronobiology Seoul National University Hospital Seoul Republic of Korea Department of Neuropsychiatry Seoul National University Hospital Seoul Republic of Korea Seoul National University Hospital Seoul Republic of Korea Department of Psychiatry Shiga University of Medical Science Otsu Japan Division of Public Health Department of Social Medicine Nihon University School of Medicine Tokyo Japan Department of Public Health Nihon University School of Medicine Tokyo Japan Division of Environmental and Preventive Medicine Department of Social Medicine Faculty of Medicine Tottori University Yonago Japan Department of Hygiene and Preventive Medicine Fukushima Medical University Fukushima Japan Department of Public Health Showa University School of Medicine Tokyo Japan Faculty of Humanities Seitoku University Matsudo Japan Section on Behavioral Science Division of Clinical Research National Hospital Organization Kurihama Alcoholism Center Yokosuka Japan Department of Otolaryngology Second Hospital Fujita Health University Nagoya Japan National Hospital Organization Kurihama Alcoholism Center Kanagawa Japan Metropolitan Police Department Criminal Investigation Laboratory Tokyo Japan Japan Somnology Center Neuropsychiatrie Research Institute Tokyo Japan Department of Somnology Tokyo Medical University Tokyo Japan Japan Somnology Center Neuropsychiatric Research Institute Tokyo Japan Department of Somnology Tokyo Medical and Dental University Tokyo Japan Center for Sleep and Chronobiology Department of Psychiatry and Behavioral Science Seoul National University College of Medicine Seoul Republic of Korea Department of Psychiatry and Behavioral Science Center for Sleep and Chronobiology Seoul Republic of Korea Department of Physiology Al

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Variable pressure hollow-core band-gap fiber cell produced using femtosecond laser micromachining

Variable pressure hollow-core band-gap fiber cell produced u...

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Conference on Lasers and Electro-Optics (CLEO)

作者： Christopher J. Hensley Daniel H. Broaddus Chris B. Schaffer Alexander L. Gaeta School of Applied & Engineering Physics Cornell University Ithaca NY USA Department of Biomedical Engineering Cornell University Ithaca NY USA

We fabricate a high-transmission, variable-pressure gas fiber cell that can operate at low and high pressures. The cell is formed by using femtosecond pulses to drill micrometer- diameter radial capillaries through a ... 详细信息

ISBN: (纸本)1557528349

关键词： Photonic band gap Fiber lasers Micromachining Ultrafast optics Focusing Petroleum Gas lasers Filling Drilling Pulse amplifiers

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A plausible mechanism for the evolution of helical forms in nanostructure growth

A plausible mechanism for the evolution of helical forms in ...

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作者： Bandaru, P.R. Daraio, C. Yang, K. Rao, A.M. Materials Science Program Department of Mechanical and Aerospace Engineering University of California San Diego San Diego CA 92093-0411 Aeronautics and Applied Physics California Institute of Technology Mail Code 105-50 Pasadena CA 91125 United States Department of Physics and Astronomy Clemson University Clemson SC 29634-0978

The observation of helices and coils in nano-tube/-fiber (NT/NF) syntheses is explained on the basis of the interactions between specific catalyst particles and the growing nanostructure. In addition to rationalizing nonlinear structure, the proposed model probes the interplay between thermodynamic quantities and predicts conditions for optimal growth. Experimental results on the effect of indium catalyst on affecting the coil pitch in NTs and NFs are presented. © 2007 The American Physical Society.

关键词： Nanotubes

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Two methods of determining [3H]dexamethasone distribution in rat subcutaneous tissue

Two methods of determining [3H]dexamethasone distribution in...

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2007 ASME Summer Bioengineering Conference, SBC 2007

作者： Dungel, Paul Hersh, Lawrence Moussy, Yvonne Biomedical Engineering Program University of South Florida Tampa FL 33620 United States Department of Physics University of South Florida Tampa FL 33612 United States Department of Mechanical Engineering University of South Florida Tampa FL 33612 United States Department of Molecular Pharmacology and Physiology University of South Florida Tampa FL 33612 United States

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Decision fusion of circulating markers for breast cancer detection in premenopausal women

Decision fusion of circulating markers for breast cancer det...

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7th IEEE International Conference on Bioinformatics and Bioengineering, BIBE

作者： Jesneck, Jonathan L. Mukherjee, Sayan Nolte, Loren W. Lokshin, Anna E. Marks, Jeffrey R. Lo, Joseph Department of Biomedical Engineering Department of Statistical Science Computational Biology and Bioinformatics Program Duke Advanced Imaging Labs. Institute for Genome Sciences and Policy Department of Computer Science Duke University Department of Electrical and Computer Engineering Division of Hematology/Oncology University of Pittsburgh School of Medicine University of Pittsburgh Cancer Institute Pittsburgh PA 15213 United States Department of Experimental Surgery Duke University Medical Center Medical Physics Graduate Program Duke University Durham NC 27708 United States

ISBN: (纸本)1424415098

Current mammographic screeningfor breast cancer is less effective for younger women. To complement mammography for premenopausal women, we investigated the feasibility screening test using 98 blood serum proteins. Because the data set was very noisy and contained only weak features, we used a classifier designed for noisy data: decision fusion. Decision fusion outperformed both a support vector machine (SVM) and linear regression with forward stepwise feature selection on all three two-class classification tasks: normal tissue vs. cancer, normal tissue vs. benign lesions, and benign lesions vs. cancer. Decision fusion detected cancer moderately well (AUC=0.84 on normal vs. cancer), demonstrating promise as a screening tool. Decision fusion also detected benign lesions similarly well (AUC=0.83 on normal vs. benign lesions) and was the only classifier to achieve any success in separating benign from malignant lesions (AUC=0.64 on benign vs. cancer). The classification results suggest that the assayed proteins are more indicative of a secondary effect, such as immune response, rather than specific for breast cancer. In conclusion, the decision fusion classifier demonstrated some promise in detecting breast lesions and outperformed other classifiers, especially for the very noisy classification problem of distinguishing benign from malignant lesions. ©2007 IEEE.

关键词： Tissue

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