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31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one: National Harbor, Md, USA. 9-13 November 2016

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J Immunother Cancer 2016年第SUPPL 1期4卷 1-1页

作者： Andreas Lundqvist Vincent van Hoef Xiaonan Zhang Erik Wennerberg Julie Lorent Kristina Witt Laia Masvidal Sanz Shuo Liang Shannon Murray Ola Larsson rolf Kiessling Yumeng Mao John-William Sidhom Catherine A. Bessell Jonathan Havel Jonathan Schneck Timothy A. Chan Eliot Sachsenmeier david Woods Anders Berglund rupal ramakrishnan Andressa Sodre Jeffrey Weber roberta Zappasodi Yanyun Li Jingjing Qi Philip Wong Cynthia Sirard Michael Postow Walter Newman Henry Koon Vamsidhar Velcheti Margaret K. Callahan Jedd d. Wolchok Taha Merghoub Lawrence G. Lum Minsig Choi Archana Thakur Abhinav deol Gregory dyson Anthony Shields Cara Haymaker Marc Uemura ravi Murthy Marihella James daqing Wang Julie Brevard Catherine Monaghan Suzanne Swann James Geib Mark Cornfeld Srinivas Chunduru Sudhir Agrawal Cassian Yee Jennifer Wargo Sapna P. Patel rodabe Amaria Hussein Tawbi Isabella Glitza Scott Woodman Wen-Jen Hwu Michael A. davies Patrick Hwu Willem W. Overwijk Chantale Bernatchez Adi diab Erminia Massarelli Neil H. Segal Vincent ribrag Ignacio Melero Tara C. Gangadhar Walter Urba dirk Schadendorf robert L. Ferris roch Houot Franck Morschhauser Theodore Logan Jason J. Luke William Sharfman Fabrice Barlesi Patrick A. Ott Laura Mansi Shivaani Kummar Gilles Salles Cecilia Carpio roland Meier Suba Krishnan dan Mcdonald Matthew Maurer Xuemin Gu Jaclyn Neely Satyendra Suryawanshi ronald Levy Nikhil Khushalani Jennifer Wu Jinyu Zhang Fahmin Basher Mark rubinstein Mark Bucsek Guanxi Qiao Cameron Macdonald Bonnie Hylander Elizabeth repasky Shilpak Chatterjee Anusara daenthanasanmak Paramita Chakraborty Kyle Toth Megan Meek Elizabeth Garrett-Mayer Michael Nishimura Chrystal Paulos Craig Beeson Xuezhong Yu Shikhar Mehrotra Fei Zhao Kathy Evans Christine Xiao Alisha Holtzhausen Brent A. Hanks Nicole Scharping Ashley V. Menk rebecca Moreci ryan Whetstone rebekah dadey Simon Watkins robert Ferris Greg M. delgoffe Jonathan Peled Sean devlin Anna Staffas Melissa Lumish Kori Porosnicu rodriguez Katya Ahr Miguel Perales Sergio Giralt Ying Taur Eric Pam Karolinska Institutet Stockholm Stockholms Lan Sweden Weill Cornell Medical College New York NY USA Nova Southeastern University Cell Therapy Institute Fort Lauderdale FL USA Johns Hopkins University School of Medicine Baltimore MD USA Immunology Program Johns Hopkins University School of Medicine Columbia MD USA Memorial Sloan Kettering Cancer Center New York NY USA Johns Hopkins Medical Institute Baltimore MD USA University of Rochester Monrovia MD USA NYU Langone Medical Center New York NY USA H. Lee Moffitt Cancer Center Tampa FL USA Ludwig Collaborative Laboratory Memorial Sloan Kettering Cancer Center New York NY USA Immune Monitoring Core Facility Memorial Sloan Kettering Cancer Center New York NY USA Leap Therapeutics Cambridge MA USA Department of Medicine Memorial Sloan Kettering Cancer Center New York NY USA Case Western Reserve University Cleveland OH USA Cleveland Clinic Main Campus Cleveland OH USA University of Virginia Cancer Center Charlottesville VA USA Stony Brook University Medical Center Stony Brook NY USA Karmanos Cancer Institute Detroit MI USA University of Texas MD Anderson Cancer Center Houston TX USA Idera Pharmaceuticals Inc. Cambridge MA USA Institut Gustave Roussy Villejuif Ile-de-France France Center for Applied Medical Research (CIMA) University of Navarra Pamplona Navarra Spain University of Pennsylvania Philadelphia PA USA Earle A. Chiles Research Institute Providence Cancer Center Portland OR USA Universitätsklinikum Essen Essen Nordrhein-Westfalen Germany University of Pittsburgh Pittsburgh PA USA CHU Rennes Service Hématologie Clinique and INSERM 0203 Unité d’Investigation Clinique Rennes Bretagne France Centre Hospitalier Régional Universitaire de Lille Lille Nord-Pas-de-Calais France Simon Cancer Center Indiana University Indianapolis IN USA University of Chicago School of Medicine Chicago IL USA Johns Hopkins University School of Medicine Lutherville MD USA Multidisciplinary Oncology and Therapeuti

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Erratum to: Making sense of big data in health research: towards an EU action plan

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Genome medicine 2016年第1期8卷 118页

作者： Charles Auffray rudi Balling Inês Barroso László Bencze Mikael Benson Jay Bergeron Enrique Bernal-delgado Niklas Blomberg Christoph Bock Ana Conesa Susanna del Signore Christophe delogne Peter devilee Alberto di Meglio Marinus Eijkemans Paul Flicek Norbert Graf Vera Grimm Henk-Jan Guchelaar Yi-Ke Guo Ivo Glynne Gut Allan Hanbury Shahid Hanif ralf-dieter Hilgers Ángel Honrado d rod Hose Jeanine Houwing-duistermaat Tim Hubbard Sophie Helen Janacek Haralampos Karanikas Tim Kievits Manfred Kohler Andreas Kremer Jerry Lanfear Thomas Lengauer Edith Maes Theo Meert Werner Müller dörthe Nickel Peter Oledzki Bertrand Pedersen Milan Petkovic Konstantinos Pliakos Magnus rattray Josep redón I Màs reinhard Schneider Thierry Sengstag Xavier Serra-Picamal Wouter Spek Lea A I Vaas Okker van Batenburg Marc Vandelaer Peter Varnai Pablo Villoslada Juan Antonio Vizcaíno John Peter Mary Wubbe Gianluigi Zanetti European Institute for Systems Biology and Medicine 1 avenue Claude Vellefaux 75010 Paris France. cauffray@***. CIRI-UMR5308 CNRS-ENS-INSERM-UCBL Université de Lyon 50 avenue Tony Garnier 69007 Lyon France. cauffray@***. Luxembourg Centre for Systems Biomedicine University of Luxembourg 7 Avenue des Hauts Fourneaux 4362 Esch-sur-Alzette Luxembourg. rudi.balling@uni.lu. Wellcome Trust Sanger Institute Wellcome Genome Campus Hinxton Cambridge CB10 1SA UK. Health Services Management Training Centre Faculty of Health and Public Services Semmelweis University Kútvölgyi út 2 1125 Budapest Hungary. Centre for Personalised Medicine Linköping University 581 85 Linköping Sweden. Translational & Bioinformatics Pfizer Inc. 300 Technology Square Cambridge MA 02139 USA. Institute for Health Sciences IACS - IIS Aragon San Juan Bosco 13 50009 Zaragoza Spain. ELIXIR Wellcome Genome Campus Hinxton Cambridge CB10 1SD UK. CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Lazarettgasse 14 AKH BT25.2 1090 Vienna Austria. Department of Laboratory Medicine Medical University of Vienna Lazarettgasse 14 AKH BT25.2 1090 Vienna Austria. Max Planck Institute for Informatics Campus E1 4 66123 Saarbrücken Germany. Príncipe Felipe Research Center C/Eduardo Primo Yúfera 3 46012 Valencia Spain. University of Florida Institute of Food and Agricultural Sciences (IFAS) 2033 Mowry Road Gainesville FL 32610 USA. Bluecompanion Ltd 6 London Street (second floor) London W2 1HR UK. Technology Data & Analytics KPMG Luxembourg Société Coopérative 39 Avenue John F. Kennedy 1855 Luxembourg Luxembourg. Department of Human Genetics Department of Pathology Leiden University Medical Centre Einthovenweg 20 2333 ZC Leiden The Netherlands. Information Technology Department European Organization for Nuclear Research (CERN) 385 Route de Meyrin 1211 Geneva 23 Switzerland. Julius Center for Health Sciences and Primary Care University Medical Center

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development of a Low Cost Anthropomorphic robot Hand with High Capability

Development of a Low Cost Anthropomorphic Robot Hand with Hi...

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IEEE/rSJ International Conference on Intelligent robotics and Systems

作者： Ji-Hun Bae Sung-Woo Park Jae-Han Park Moon-Hong Baeg doik Kim Sang-rok Oh Robot Convergence R&D Group Korea Institute of Industrial Technology(KITECH) Ansan R&D Center 1271-18 Sa-3-dong Sangrok-gu Ansan Korea Interaction and Robotics Research Center Korea Institute of Science & Technology Hwarangno 14-gil 5 Seongbuk-gu Seoul 130-650 Korea

ISBN: (纸本)9781467317375

This paper presents a development of an anthropomorphic robot hand, 'KITECH Hand' that has 4 full-actuated fingers. Most robot hands have small size simultaneously many joints as compared with robot manipulators. Components of actuator, gear, and sensors used for building robots are not small and are expensive, and those make it difficult to build a small sized robot hand. differently from conventional development of robot hands, KITECH hand adopts a rC servo module that is cheap, easily obtainable, and easy to handle. The rC servo module that have been already used for several small sized humanoid can be new solution of building small sized robot hand with many joints. The feasibility of KITECH hand in object manipulation is shown through various experimental results. It is verified that the modified rC servo module is one of effective solutions in the development of a robot hand.

关键词： verified building development

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robotic Arm Control Inspired by Human Muscle Tension Effect under the Gravity

Robotic Arm Control Inspired by Human Muscle Tension Effect ...

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2011 IEEE International Conference on robotics and Automation(2011年IEEE世界机器人与自动化大会 ICrA 2011)

作者： Ji-Hun Bae Woosung Yang Sang-rok Oh Bum-Jae You doik Kim Yonghwan Oh Department of Applied Robot Technology Korea Institute of Industrial TechnologyAnsan R&D Center127 Human Factors & Devices Research Team Central Advanced Research & Engineering Institute of Hyundai M Cognitive Robotics Center Korea Institute of Science & TechnologyP.O. BOX 131CheongryangSeoul 130

In recent, control approaches for the human-like behavior in the field of service robotics have been attracting considerable attention, since most humans or animals perform various tasks uncomplicatedly. Hence simple control methods based on gaining a physical insight into human reaching movement in redundancy of dOFs have been proposed. In comparison with the conventional approaches, the proposed method tries to control directly robotic systems in task-space with the control signal composed of linear superposition of three terms 1) joint-damping, 2) virtual spring, and 3) virtual damper in task-space. In particular, our work contains a muscle tension effect of a human under the gravity. This give birth to energy efficient natural motions avoiding problems on repeatability of the motion and ill-posedness problems emerged in most of redundant dOF systems. Thus, this paper exhibits expendability of the position control into the orientation control and compliant behavior. It is verified with a real robotic arm that satisfies human-like movements and motion repeatability under kinematic redundancy of joints.

关键词： robot arm control Human-like motion redundant robots Manipulation

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Microstructure and mechanical properties of die-cast AZ91d magnesium alloy by Pr additions

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Transactions of Nonferrous Metals Society of China 2010年第B07期20卷 435-438页

作者：崔晓鹏刘海峰孟健张德平 Department of Materials Science and Engineering Key Laboratory of Advanced Structrural Materialsof Ministry of EducationChangchun University of Technology State Key Laboratory of Rare Earth Resources Utilization Changchun Institute of Applied ChemistryChinese Academy of Sciences R&D Centre of Foundry Corporation FAW Group Corporation

Mg-9Al-xPr(x=0.4,0.8 and 1.2,mass fraction,%)magnesium alloys were prepared by high-pressure die-casting *** effects of Pr on the microstructures of die-cast Mg-9Al based alloy were investigated by Xrd and ***-like Al11Pr3 phase and polygon Al6Mn6Pr phase are found in the *** 0.4%Pr addition,fine needle-like Al11Pr3 phase and a small amount of polygon Al6Mn6Pr phase near the grain boundary are found in the *** Pr addition to 0.8%, lots of coarse needle-like Al11Pr3 phase within grain and polygon Al6Mn6Pr phase on grain boundary are *** increasing Pr addition,the size of needle-like Al11Pr3 phase decreases,while the size of polygon Al6Mn6Pr relatively *** mass fraction of Pr at around 0.8%is considered to be suitable to obtain the optimal mechanical *** optimal mechanical properties are mainly resulted from grain boundary strengthening obtained by precipitates and solid solution.

关键词： praseodymium magnesium alloy microstructure mechanical properties

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dy/sup 3+/-doped Ge-Ga-S-KBr (or CsBr) glasses for the 1.3 /spl mu/m fiber amplifier materials

Dy/sup 3+/-doped Ge-Ga-S-KBr (or CsBr) glasses for the 1.3 /...

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Optical Fiber Communication (OFC) Conference

作者： Jong Heo Yong Beom Shin Hyoun Soo Kim Applied Optics R&D group Samsung Electronics Company Limited Pohang South Korea Non-Cry stalline Materials Laboratory Department of Materials Science and EngineeringBchool of Environmental Engineering Pohang University of Science and Technology South Korea

The addition of CsBr and KBr in Ge-Ga-S glasses doped with dy/sup 3+/ showed a remarkable increase in the 1.32 /spl mu/m emission intensity. Lifetimes and quantum efficiency also increased to 700 /spl mu/s and 100%, r... 详细信息

关键词： Glass Spectroscopy Absorption Stationary state Gain measurement Position measurement Fluorescence Solids

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AIr-CUSHION LANdING CrAFT NAVIGATION

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NAVAL ENGINEErS JOUrNAL 1985年第4期97卷 248-260页

作者： GrAHAM, Hr KIM, JC BANd, EGU FOWLEr, AW Herbert R. Graham:received his degrees of B.S. in 1951 and M.S. in 1958 in aeronautical engineering from the Massachusetts Institute of Technology and the California Institute of Technology respectively. He also attended the Harvard Graduate School of Business Administration. He is presently a task manager at TRW Inc. McLean Virginia responsible for landing craft air cushion (LCAC) engineering support. Since joining TRW in 1967 he has had several technical project management and system engineering responsibilities in amphibious ships transportation and energy. He was responsible for the preliminary engineering design and cost estimates for tracked air cushion vehicles (TACVs). He has been active in several professional societies including ASNE and served as vice-chairman Los Angeles Section American Institute of Aeronautics and Astronautics. John C. Kim:received his degrees of B.S. in electrical engineering Tri-State University 1959 M.S. in electrical engineering Michigan State University 1960 and Ph.D. in electrical engineering Michigan State University. He is presently a senior staff engineer with TRW Inc. McLean Virginia where his technical experience has included communications system engineering and navigation system analysis. Since joining TRW in 1969 he has held numerous positions including section head project manager and department manager. His previous employment includes E-Systems/Melpar Division and Honeywell. Dr. Kim has been active in the IEEE Washington Chapter activities which included secretary vice-chairman and chairman of Systems Science and Cybernetics Group. Edward G.U. Band:received a B.S. degree in mechnical engineering in 1946 and a D.I.C in aeronautical engineering in 1947 at the City and Guilds College of London University. In 1951 he received an M.S. degree from Stevens Institute of Technology in fluid dynamics. After a career in the aircraft industry in England Canada and the U.S.A. he spent several years teaching in Chile and at Webb Institute of Naval Archi

Air cushion vehicles (ACVs) have operated successfully on commercial routes for about twenty years. The routes are normally quite short; the craft are equipped with radar and radio navigation aids and maintain continuous contact with their terminals. Navigation of these craft, therefore, does not present any unusual difficulty. The introduction of air cushion vehicles into military service, however, can present a very different picture, especially when external navigation aids are not available and the craft must navigate by dead reckoning. This paper considers the problems involved when navigating a high-speed air cushion vehicle by dead reckoning in conditions of poor visibility. A method is presented to assess the ACV's navigational capability under these circumstances. A figure of merit is used to determine the sensitivity of factors which affect navigation such as the range of visibility, point-to-point distance, speed, turning radius and accuracy of onboard equipment. The method provides simplistic but adequate answers and can be used effectively to compare the-capability and cost of alternative navigation concepts.

关键词： AIr CUSHION VEHICLES

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HUMAN-FACTOrS CONSIdErATIONS applied TO OPErATIONS OF THE FFG-8 ANd LAMPS MK III

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NAVAL ENGINEErS JOUrNAL 1984年第3期96卷 191-199页

作者： BAITIS, AE APPLEBEE, Tr MCNAMArA, TM A. Erich Baitis: a native of Germany came to the David W. Taylor Naval Ship R&D Center in 1957 as a cooperative student/trainee and received his B.S. degree in physics from Virginia Polytechnic Institute. As a 32-year-old naval architect in 1971 he received both the Vietnam Honor Service Medal and the Navy's Meritorious Civilian Service Award for his eight months as liaison with the Vietnamese Navy's ferro-cement program. As head of the Seakeeping and Stabilization Group of the Surface Ship Dynamics Branch his work has led to the development of a new standard Ship Motion Computer Program and the application of ship motions to ship habitability operability and survivability problems. A major area of this work has been the ship-aircraft interface which is particularly sensitive to ship motions wind and other environmental factors. He is a member of the American Society of Naval Engineers and was awarded the Solberg Award for 1982 “in recognition of significant engineering research and development contributions in the area of improved helicopter operations from a ship in a seaway.” Terrence A. Applebee:is currently a naval architect at the David W. Taylor Naval Ship R&D Center in the Surface Ship Dynamics Branch. he came to the Center after earning a B.S. degree in ocean engineering from Florida Institute of Technology in 1973. Since that time he has worked in the areas of seakeeping performance evaluation ship-helicopter interfacing and human factor considerations. He is a member of the American Society of Naval Engineers and the Society of Naval Architects and Marine Engineers. Thomas M. McNamara:is an employee of the John Hopkins University Applied Physics Laboratory in the ocean data acquisition program. From 1979 to 1983 he worked at David W. Taylor Naval Ship R&D Center in the Surface Ship Dynamics Branch. His expertise has focused on the development of computer models for human factor evaluations as well as motion stabilization systems. He has participated in the development of advanced stabilizat

The FFG 7/LAMPS MK III Operator Guidance Manual (OGM) was developed for all FFG-7 class frigates which are not fin stabilized or are operating with the fins off. The OGM was developed to assis the ship operators of the FFG-7 class in choosing ship speed and heading combinations which will minimize ship motion-related problems during various phases of the LAMPS deployment. Crew safety and performance were major concerns in the development of the OGM. This paper reviews the effect of human factors on ship operations during helicopter recovery, maintenance, and transit to and from the hangar.

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AN AdVANCEd METHOdOLOGY FOr PrELIMINArY HULL FOrM dEVELOPMENT

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NAVAL ENGINEErS JOUrNAL 1984年第4期96卷 147-161页

作者： LIN, WC dAY, WG HOUGH, JJ KEANE, rG WALdEN, dA KOH, IY Wen-Chin Lin:heads the Ship Powering Division at the David Taylor Naval Ship R&D Center (DTNSRDC). Dr. Lin received his B.S. degree in mechanical engineering from the National Taiwan University in 1957. He was awarded his M.S. degree in naval architecture and Ph.D. in engineering science from the University of California at Berkeley in 1963 and 1966 respectively. From 1966 to 1969 he was employed by ESSO Research and Engineering Company to conduct marine hydrodynamic research for oil tankers and offshore structures. Since joining DTNSRDC in 1969 he has actively conducted and directed hydrodynamic research to advance naval ship design technology and improve ship performance. Active in national and international symposia on ship hydrodynamic research he is recognized for contributions to the ship research community. For the past six years he has been a member of the Performance Committee of the ITTC and currently serves as secretary of the committee. He is a member of SNAME and the Society of Naval Architects of Japan. William G. Day Jr:. has been employed as a naval architect at the David Taylor Naval Ship R&D Center since receiving a B.E.S. degree from the Johns Hopkins University in 1966. He obtained an M.S. E. degree from George Washington University in 1971. As Head Design Evaluation Branch of the Ship Performance Department he is responsible for model experiments to evaluate the hydrodynamic performance of ships and propulsors. He is a member of ASNE and SNAME. In-Young Koh:received his B.S. and M.S. degrees in electrical engineering from Lowell University in 1969 and 1971 respectively and his Ph.D. in applied mechanics from Rensselaer Polytechnic Institute in 1976. Dr. Koh joined DTNSRDC as an electronic engineer specializing in the application of advanced instrumentation and computer techniques to ship research and design. He is currently engaged in research and development of active control systems for naval ship applications. Dr. Koh is a member of ASNE SNAME and IEEE. David Andrew Walden:is

A ship design methodology is presented for developing hull forms that attain improved performance in both seakeeping and resistance. Contrary to traditional practice, the methodology starts with developing a seakeeping-optimized hull form without making concessions to other performance considerations, such as resistance. The seakeeping-optimized hull is then modified to improve other performance characteristics without degrading the seakeeping. Presented is a point-design example produced by this methodology. Merits of the methodology and the point design are assessed on the basis of theoretical calculations and model experiments. This methodology is an integral part of the Hull Form design System (HFdS) being developed for computer-supported naval ship design. The modularized character of HFdS and its application to hull form development are discussed.

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SEAKEEPING PErFOrMANCE COMPArISON OF AIr CAPABLE SHIPS

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NAVAL ENGINEErS JOUrNAL 1982年第2期94卷 101-117页

作者： COMSTOCK, EN BALES, SL GENTILE, dM Mr. Edward N. Comstock:is currently Head of the Hull Form Design and Performance Branch (SEA 3213) of the Naval Sea Systems Command. He received his B.S.E. degree in Naval Architecture and Marine Engineering in 1970 and his M.S.E. degree in Ship Hydrodynamics in 1974 both from the University of Michigan. Mr. Comstock began his career with theU.S. Navyin 1974 as a Seakeeping Specialist in the Hull Form and Fluid Dynamics Branch of the former Naval Ship Engineering Center. Achieving his present position in January 1982 Mr. Comstock was previously Head of the Surface Ship Hydrodynamics Section of SEA 3213 being responsible for recent hull form designs including DDG-51 MCM-1 and ARS-50. Before obtaining that position in 1979 Mr. Comstock's efforts were primarily aimed at developing and establishing seakeeping performance assessment and design practices. Prior to his employment by the Navy Mr. Comstock worked in the Structural and Hydrodynamics Group of General Dynamics' Electric Boat Division. A member of ASNE he is also a member of ASE and SNAME and has been active in supporting the efforts of the SNAME H-7 (Seakeeping) Panel SNAME HS-12 (Hull Instrumentation) Panel the National Science Foundation (NSF) and the NATO Armaments Group IEG6/Sub-Group 5 (Seakeeping). Ms. Susan L. Bales:has been associated with the David W. Taylor Naval Ship R&D Center (DTNSRDC) and its predecessor organizations throughout her professional career. She is currently Head of the Ocean Environment Group of the DTNSRDC Surface Ship Dynamics Branch (1561) and also serves as the DTNSRDC Program Manager of the Navy's Exploratory Development Program on Surface Waves. Her work documented by more than fifty technical publications has been directed primarily to ship seakeeping ocean environment and ship performance assessment problems. An internationally recognized authority in her field she is also active in several professional societies as well as the SNAME H-7 (Seakeeping) Panel the National Science Foundation (NSF) and the NA

The on-going debate regarding the merits of large versus small aircraft carriers raises several issues concerning the ability of various ship configurations to support sea based air operations. One such issue is the question of the relative seakeeping performance of ship alternatives. In an effort to shed some light on the matter, a comparative seakeeping assessment of nine air capable ships covering a wide range of size and hull form was performed. An evaluation of the impact of aircraft and ship motion limitations on sea based air operations and a comparison of the relative ability of the ships to conduct air operations while in a seaway are presented. The specific air operations considered are launch, recovery, and support of aircraft. The ships evaluated are CVN-71, CVA-67 (Mr), CVV, LHA-1, VSS-d, ddV-2, ddV-1d, dd-963, and SWATH-6. These ships have the combined capability to operate Vertical Takeoff and Landing (VTOL), Conventional Takeoff and Landing (CTOL), Short Takeoff and Arrested Landing (STOAL), and Short Takeoff and Vertical Landing (STOVL) type aircraft. results indicate that seakeeping performance generally degrades with decreasing displacement, that SWATH-6 performance is the least degraded, that elevator wetness can be an important degrader for ships with lower freeboards, that roll motion can be an important degrader for ships under 60,000 tons, and that percent time of operation is strongly dependent on the prevailing wave and wind environment.

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