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SSRN 2024年

作者： Choi, Seeun Kim, Jimin Kim, Handon Cho, Hyunsang Jang, Hyounseung Architectural Engineering Program School of Architecture Seoul National University of Science and Technology Seoul01811 Korea Republic of

As the importance of indoor environment quality (IEQ) increases, it is crucial to secure IEQ uniformity so that all occupants in stair-type lecture halls perform learning activities in a comfortable IEQ. Therefore, this study analyzed IEQ uniformity through a comprehensive analysis by influence factors, such as occupancy level or climate when using existing electric heat pump (EHP) systems. Also analyzed the improvement of IEQ uniformity when using a fabric air dispersion (FAD) system instead of EHP system, securing IEQ uniformity through air conditioning (AC) systems. Computational fluid dynamic (CFD) result show that when the EHP system was used, the uniformity of the indoor air temperature (IAT), predicted mean vote (PMV), and carbon dioxide (CO2) in stair-type lecture halls, both in summer and winter, decreased as the occupancy level increased. On the other hand, when the FAD system was applied, the average for max difference of IAT, PMV, and CO2 in summer and winter decreased by more than 50% compared to the use of EHP system. Furthermore, levels that do not exceed the comfort level in the total area based on PMV increased by 15% in summer and 10% in winter. It is expected that it will contribute to the occupants’ well-being and the improvement of productivity and work performance in various types of building through the elaboration of the FAD system that is effective in securing IEQ uniformity. © 2024, The Authors. All rights reserved.

关键词： Computational fluid dynamics

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Optimization of spray-drying process parameters for microencapsulation of three probiotic lactic acid bacteria selected by their high viability rate in sucrose and fructose levels and high temperatures

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Systems Microbiology and Biomanufacturing 2024年第2期4卷 687-698页

作者： Elif Seyma Bagdat Perihan Kübra Akman Gozde Kutlu Fatih Tornuk Food Processing Department Kahramankazan Vocational SchoolProgram of Food TechnologyBaşkent UniversityAtatürkİstiklal Cd.No:2706980 Kahramankazan/AnkaraTürkiye Food Engineering Department Chemicaland Metallurgical Engineering FacultyYildiz Technical UniversityDavutpasa Campus34210 IstanbulTürkiye Department of Gastronomy and Culinary Arts Faculty of Fine ArtsDesign and ArchitectureAnkara Medipol UniversityAnkaraTürkiye

Microencapsulation is an efficient way to increase the survival rate of probiotics against harsh *** this study,three probiotic strains(Lactiplantibacillus plantarum *** strain W2(LP4),Lactiplantibacillus pentosus strain XL640(LPE1),and Limosilactobacillus fermentum strain W8(LF2)),isolated from shalgam and gilaburu,were microencapsu-lated with spray drying and process conditions[maltodextrin concentration(MC,10–30%)and inlet air temperature(IAT,110–130℃)]were optimized by central composite rotatable design of response surface *** results indicated that the predicted IAT and MC values for the maximum powder yield and viability were 123.21℃ and 22.76%,130.37℃ and 19.49%,and 127.94℃ and 10.00%for LF2,LP4 and LPE1,*** these conditions,bacterial viability ranged from 10.27 to 10.33 log colony-forming units per gram(cfu/g),while the powder yield values for the encapsulation of the bacteria were between 43.38%and 50.97%.Furthermore,MC was the most significant factor for the powder yield of LF2,LPE1,and viability of *** efficiency values higher than 92.77%demonstrated the efficiency of spray dry-ing for the protection of selected *** microcapsules produced at the optimum points had moisture content between 5.30 and 5.96%.SEM images showed that the microcapsules were in spherical *** conclusion,the results confirmed that the selected probiotics were successfully microencapsulated with spray drying with high powder yield,viability,and encapsulation efficiency levels and these features could reveal the potential of the encapsulated probiotic strains to be used in high-sugar foods.

关键词： Microencapsulation Spray drying Response surface methodology Lactiplantibacillus plantarum Lactiplantibacillus pentosus Limosilactobacillus fermentum

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mRNA vaccines: Past, present, future

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Asian Journal of Pharmaceutical Sciences 2022年第4期17卷 491-522页

作者： Mia Karam Georges Daoud Biomedical Engineering Program Maroun Semaan Faculty of Engineering and ArchitectureBeirut 11072020Lebanon Department of Biochemistry and Molecular Genetics Faculty of MedicineBeirut 11072020Lebanon Department of Anatomy Cell Biologyand Physiological SciencesFaculty of MedicineAmerican University of BeirutBeirut 11072020Lebanon

mRNA vaccines have emerged as promising alternative platforms to conventional *** ease of production,low cost,safety profile and high potency render them ideal candidates for prevention and treatment of infectious diseases,especially in the midst of *** challenges that face in vitro transcribed RNA were partially amended by addition of tethered adjuvants or co-delivery of naked mRNA with an adjuvanttethered ***,it wasn’t until recently that the progress made in nanotechnology helped enhance mRNA stability and delivery by entrapment in novel delivery systems of which,lipid *** continuous advancement in the fields of nanotechnology and tissue engineering provided novel carriers for mRNA vaccines such as polymeric nanoparticles and *** studies have shown the advantages of adopting mRNA vaccines for viral diseases and cancer in animal and human ***-amplifying mRNA is considered today the next generation of mRNA vaccines and current studies reveal promising *** review provides a comprehensive overview of mRNA vaccines used in past and present studies,and discusses future directions and challenges in advancing this vaccine platform to widespread clinical use.

关键词： mRNA vaccine Virus Cancer Nanoparticles COVID-19

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Development of Inkjet-Printed PEDOT:PSS-Based Organic Electrochemical Transistor (OECT) for Biopotential Amplification

Development of Inkjet-Printed PEDOT:PSS-Based Organic Electr...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Fadi C. Khoury Sahera A. Saleh Zeina S. Habli Massoud L. Khraiche Neural Engineering and Nanobiosensors Group Biomedical Engineering Program Maroun Semaan Faculty of Engineering and Architecture American University of Beirut Lebanon

With the ever-increasing need for miniaturized and biocompatible devices for physiological recordings, high signal fidelity and ease of fabrication are key to achieve reliable data collection. This calls for the development of active recording devices such as Organic Electrochemical Transistors (OECTs) which, compared to passive electrodes, offer local amplification. In this work, we built PEDOT:PSS based OECTs using novel inkjet printing technology, achieving a transconductance of 75 mS. The device was later used to amplify arbitrary signals simulating in vivo recordings. Gate voltage offset manipulation offered a range of current peak-to-peak amplitudes. Additionally, we demonstrate a simple circuit for voltage readings, where another resistor-dependent characterization involving voltage source and drain voltage is performed. At ideal operating point and when using a 220 Ω resistor, a gain of 14.5 is *** Relevance— 1 This work demonstrates the ability to rapidly and easily develop OECT-based technology for potential signal sensing for more accurate diagnosis of pathologies and diseases.

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Belém 20|50 ºC: A New Model of Sustainable and Climate-Resilient Social Housing for Belém-Brazil

SSRN

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SSRN 2024年

作者： Zemero, Bruno Ramos Barata, Márcio Santos Monteiro, Giovanna Bentes Braga, Jhonata Lima Gonçalves, Eduarda Lorrany Sousa dos Santos Batista, Vitor Michelon, Michelli Gonçalves da Cunha, Luís Filipe Brasil Dutra, Ana Beatriz Nobre Alves de Medeiros Machado, Rebecca Teixeira, Reyso Cunha Postgraduate Program in Architecture and Urbanism Federal University of Pará Brazil Faculty of Architecture and Urbanism Federal University of Pará Brazil Faculty of Computer Engineering Federal University of Pará Brazil

The city of Belém experiences a hot and humid equatorial climate and faces the threats of global warming, aiming to become the second hottest city in the world by 2050, according to The Washington Post. As the host of COP-30 in November 2025, the city requires special attention to ensure the safety and quality of life for its population. This research aims to provide sustainability (social, economic, and environmental) and resilience (mitigation and adaptation to climate change) through a prototype of Social Interest Housing (HIS) with the potential for replication in municipal and national housing policies. © 2024, The Authors. All rights reserved.

关键词： Housing

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Development of Supported Catalyst for Hydrogen Production from Sodium Borohydride

Development of Supported Catalyst for Hydrogen Production fr...

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2024 IEEE Global Energy Conference, GEC 2024

作者： Sayilgan, Ahmet Onat, Erhan Ekinci, Selma Izgi, Mehmet Sait Tatvan Vocational School Electricity and Energy Program Bitlis Eren University Bitlis Turkey Organized Industrial Zone Vocational School Electricity and Energy Program Bitlis Eren University Bitlis Turkey Vocational School of Technical Sciences Department of Chemistry and Chemical Process Technology Batman University Batman Turkey Faculty of Engineering Architecture Siirt University Siirt Turkey

ISBN: (纸本)9798331532611

The best solution to the problems caused by fossil fuels and the limitations of renewable energy sources is the conversion of hydrogen into energy in fuel cells. The transportation and storage problems, which are the main obstacles to the conversion of hydrogen into energy in fuel cells, can be overcome by storing hydrogen in boron compounds. The recovery of hydrogen stored in boron compounds when needed is carried out through catalytic processes. In this study, a supported catalyst was synthesized for use in hydrogen production from sodium borohydride (SBH), which is one of the main boron compounds used in the solid storage of hydrogen, and the dehydrogenation parameters of the synthesized catalyst were investigated. In this context, chenopodium botrys plant extract was used as a support material for nickel (Ni) metal atoms. At the end of the extraction carried out through a hydrothermal process, Ni atoms were decorated using the impregnation method in the extract, and the Ni@KBHE catalyst was produced via reduction under SBH. After the washing, filtration, and drying processes were carried out under a nitrogen atmosphere, the solution medium, catalyst amount, SBH concentration, and temperature parameters of SBH hydrolysis with the crumbled catalyst were optimized. Optimum values for hydrogen production were obtained using 5% NaOH, 60 mg of catalyst, and 2% SBH. The hydrogen production rate (HGR) at these values was 4664 mL/g min. As a result of the catalytic reaction kinetic calculations, it was determined that the reaction was nth order, and the reaction activation energy was 49.4 kJ/mol. ©2024 IEEE.

关键词： Activation energy

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DIGITALIZATION of CITIES-SMART CITY INTERVENTIONS in the CASE of SARAJEVO 6

DIGITALIZATION of CITIES-SMART CITY INTERVENTIONS in the CAS...

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6th International Conference on Smart City Applications

作者： Hudović Kljuno, A. Krivošić Dizdarević, L. Architecture Program Faculty of Engineering and Natural Sciences International University of Sarajevo Bosnia and Herzegovina

Many countries in the world are becoming more aware of climatic changes, rising pollution, and running out of resources, predicting their impact on the future of humanity thus giving solutions for slowing down this process. Due to the mass urbanization of our planet, it became highly popular to talk about resilient and smart cities. And while some countries are still on a theoretical level, others, more advanced in their thinking and technical possibilities and with the higher consciousness of the importance of this issue are already putting things into action. European Union gives guidelines on how cities across Europe can improve in the future. There are several good examples of different actions across European countries that make their cities more resilient, more sustainable, and pleasant for living. Contrarily, in the cities of the developing European countries such as Bosnia and Herzegovina, the idea of resilient and Smart cities is still in its infancy. This paper aims to introduce different parameters that make cities more resilient and to show several of the best practices from Europe which use Smart city technologies while questioning the current situation in Sarajevo, the capital of Bosnia and Herzegovina. Authors are introducing potentials of Sarajevo and smaller projects that can be starting points in the process of improvement of habitat climate in this city and its transformation to a smart and sustainable city. © Author(s) 2021. CC BY 4.0 License.

关键词： Smart city

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Modeling of Calcium-dependent Low Intensity Low Frequency Ultrasound Modulation of a Hodgkin–Huxley Neuron

Modeling of Calcium-dependent Low Intensity Low Frequency Ul...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Heba M. Badawe Massoud L. Khraiche Neural Engineering and Nanobiosensors Group Biomedical Engineering Program Maroun Semaan Faculty of Engineering and Architecture American University of Beirut Beirut Lebanon

Non-invasive low intensity, low frequency ultrasound is a progressive neuromodulation approach that can reach deep brain areas with peak spatial and temporal resolution for highly-targeted diagnostic and therapeutic purposes. Coupling the ultrasound mechanical effects to the neural membrane comprises different mechanisms that are, to-date, still a topic of debate. The availability of calcium ions in the extracellular medium is of high significance when it comes to the effect of ultrasound on the neural tissue. Whereby the generated calcium influx can directly affect the voltage-gated ion channels, amplifying their action. We modeled the flexoelectric-induced effects of ultrasound to a single firing neuron, taking into consideration the effect of calcium channel embedding into the neural membrane on the neuron’s firing rate, latency response, peak-to-peak voltage, and general shape of the action *** Relevance— Upon Ultrasound sonication, the mechanical waves interact with the neural membrane and alter the kinetics of the calcium channels, thus changing the neural response.

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Design and Experiment of a Water Hydraulic Artificial Muscle Actuated Diving Auxiliary Operating System 9

Design and Experiment of a Water Hydraulic Artificial Muscle...

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9th International Conference on Fluid Power and Mechatronics, FPM 2023

作者： Che, Jin-Kai Zhang, Zeng-Meng Yang, Yong Wang, Ji-Xiang Chen, Yin-Long Gong, Yong-Jun Yang, Rui College of Naval Architecture and Ocean Engineering Dalian Maritime University Dalian China Dalian University of Technology Open Research Program of Key Laboratory for Precision and Non-traditional Machining Technology of Ministry of Education of China Dalian China

ISBN: (数字)9798350304947

ISBN: (纸本)9798350304947

A diving auxiliary operating system based on water hydraulic artificial muscle (WHAM) was developed to enhance the efficiency of underwater work for divers. The water filling pressure of the WHAM was calculated by the interaction torque between the operating system and the wearer. Power assisted experiments were conducted to imitation the underwater rigging connections, desilting, and obstacle clearance for rescue operations. The power assistance effect was evaluated through a comparison of the surface electromyography (EMG) intensity between the wearer with and without the auxiliary operating system. The experiments results indicate that the auxiliary system can enhance the diver's operational capacity 43%. © 2023 IEEE.

关键词： Muscle

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Achievement of green campus indications based on assessment indicators on H-BAT program Universitas Negeri Semarang 9

Achievement of green campus indications based on assessment ...

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9th engineering International Conference, EIC 2020

作者： Prihanto, T. Fathoni, K. Prasetiyo, B. Study Program of Architecture Faculty of Engineering Universitas Negeri Semarang Indonesia Study Program of Electrical Engineering Faculty of Engineering Universitas Negeri Semarang Indonesia Study Program of Informatics Universitas Negeri Semarang Indonesia

Universitas Negeri Semarang (UNNES) has a spirit to become a Conservation and International Reputation University is realized through strategic missions. One of the conservation-oriented implementation programs is H-BAT (Green, Clean and Healthy) program. In its implementation, there is a problem, namely the achievement of H-BAT program has not been maximized during the last 3 years in assessment. The objectives of this research are: (1) to identify of the potential and character of environmental support in the work units;(2) to determine the achievement of the indication of a green campus based on the assessment indicators on H-BAT program. This research was carried out in four stages: (1) Data collection;(2) Spatial data processing;(3) Non Spatial data processing;(4) Analysis (ecological, technical standards);The results achieved in June 2020 are as follows: FT got 87,50%, FE got 85,87%, FMIPA got 81,52%, BUHK got79,49%, FIP got 73,91%, LP3 got 69,23%, LP2M got 63,46%, FIS got 60,33%,PPS got 57,07%, FIK got 56,52%, FH got 52,72%, FBS got 49,46%, TIK got 40,38%, BPB got 34,62%, Library got 30,13%, Archive got 17,31%. From these results, it can be seen that there is a lack of maximum achievement due to, among others, the lack of guidance and technical assistance in the management of the unit. So it is necessary to complete governance guidelines and technical assistance that are more intensive in unit governance to achieve the goals of UNNES as a green campus. © Published under licence by IOP Publishing Ltd.

关键词： Data handling

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