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Detection of retinitis pigmentosa stages with GAN and transfer learning in maps of MfERG P1 wave amplitudes

Signal, Image and Video Processing 2025年第7期19卷 1-24页

作者： Güven, Aysegül Karaman, Bayram Öner, Ayse Sinim Kahraman, Neslihan Department of Biomedical Engineering Engineering Faculty Erciyes University Kayseri Turkey Biomedical Engineering Graduate Program Graduate School of Natural and Applied Sciences Erciyes University Kayseri Turkey Department of Electrical and Electronics Engineering Engineering and Architecture Faculty Tokat Gaziosmanpasa University Tokat Turkey Department of Ophthalmology Acıbadem Taksim Hospital Istanbul Turkey Department of Ophthalmology Acıbadem University Istanbul Turkey

Retinitis pigmentosa (RP) is an inherited disease caused by the dysfunction of photoreceptor cells in the retina. Effective management and therapy are crucial to delaying or preventing vision loss and blindness, making RP a leading cause of inherited retinal disorders globally. This study is the first to utilize maps of P1 wave amplitudes from multifocal electroretinography for the automatic identification and staging of RP. We enhanced raw data with image preprocessing, traditional image augmentation, and generative adversarial networks (GAN) to create comprehensive datasets, followed by classification using five transfer learning models. Initial results indicated overfitting, mitigated through advanced preprocessing and augmentation. Performance metrics showed that the Deep Convolutional GAN model effectively eliminated overfitting. ResNet50 achieved the highest performance in four-class classification with 95.2% recall, 95.2% precision, 94.9% accuracy, 98.2% specificity and 95.2% F1 score. These results suggest that maps of P1 wave amplitudes are valuable indicators for differentiating RP stages, highlighting their potential for improving RP diagnosis and management.

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Partitioning Uncertainty from Climate Change Inputs on Streamflow Projections in the Bicol River Basin, Philippines

SSRN

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SSRN 2025年

作者： Bañares, Ernie Nograles Mehboob, Muhammad Shafqat Panda, Manas Ranjan Engineering Graduate Program School of Engineering University of San Carlos Cebu City6000 Philippines College of Engineering and Architecture Sorsogon State University Sorsogon City4700 Philippines Department of Civil Engineering School of Engineering University of San Carlos Cebu City6000 Philippines Department of Civil & Environmental Engineering Yonsei University Seoul Korea Republic of

Increasing threats to global water resources from climate change emphasize the importance of comprehending its impacts on hydrology for effective water management. This article quantifies climate input uncertainty in streamflow projections for the Libmanan-Pulantuna Watershed (LPW) in the Bicol River Basin, Philippines. Using the Water Evaluation and Planning (WEAP) model, we simulated streamflow based on future climate projections (FCPs) from Intergovernmental Panel on Climate Change (IPCC) greenhouse-gas emission scenarios, utilizing Coupled Model Intercomparison Project phases 5 (CMIP5) and 6 (CMIP6) datasets. Four Global Circulation Models (GCMs) and three bias correction techniques (Linear Scaling, Quantile Mapping, and Detrended Quantile Mapping) were applied. Results showed significant differences between the CMIP datasets, with raw CMIP6 better capturing historical climate patterns. Bias correction methods reduced projection biases in precipitation and air temperatures. Projections revealed increasing low flows and decreasing high flows, especially under high-emission scenarios, worsening water shortages during critical periods. Analysis of Variance (ANOVA) showed that climate models were a major source of uncertainty in hydrological projections. Combined FCPs and GCMs contributed to 50%-75% of total uncertainty across flow percentiles and future periods (near-future, mid-future, far-future). These findings underscore the importance of careful model selection and effective bias correction for reliable hydrological projections, crucial for water management strategies in areas like the Bicol River Basin, where water resources are essential for communities and ecosystems. © 2025, The Authors. All rights reserved.

关键词： Rivers

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Study on accumulated deflection caused by inelastic earthquake response in large-span moment frames made of H-shaped steel

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Journal of Structural and Construction Engineering 2018年第748期83卷 819-826页

作者： Iwasawa, Ryo Yamashita, Tetsuo Architecture Program in Graduate School Kogakuin University Japan School of Architecture Kogakuin University Japan

Large-span steel moment frames are used as the main structure in many gymnasiums. Several studies pointed out that significant deflection in such moment frames was caused by inelastic seismic response for horizontal earthquake ground motion. This paper explains how horizontal excitation causes large accumulated deflection, and theoretically formulates the relations between vertical deflection and inelastic deformation. The moment frames made of H-shaped steel is considered herein, where shear yield of panel zones occur in advance to forming flexural yield hinges. Since gymnasiums are used as shelters in earthquake disaster, we need a method to evaluate the structural damage quantitatively, by inspecting and measuring the deformed gymnasium. By measuring the deflection after earthquake, we might be able to estimate the plastic deformation. In this paper, the possibility is discussed using FE dynamic response analysis. The mechanism how horizontal deformation causes accumulated deflection is summarized as follows. In elastic behavior, the moment distribution in the beam for horizontal load is antisymmetric. After forming two yield hinges at two ends of the beam, the moment distribution does not change and is also antisymmetric. In the both cases, the deflection does not increase. However, when only one yield hinge is formed at the leeward side, the deflection increases with the horizontal load due to the change of moment distribution until two hinges are formed. In this paper, bi-linear constitutive relation between the shear strain and moment acting on the panel zone is assumed and theoretical solution on the behavior is derived. The theoretical solution was verified by pushover FE analysis and good agreement was observed. By applying the derived theoretical formulas, ductility factor on the both panels can be estimated from the deflection. Dynamic response analysis was also performed to verify the estimation. This could be a useful method to estimate structural dama

关键词： Strain hardening

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FORMFINDING AND BUCKLING ANALYSIS OF THREE-WAY KAGOME TIMBER LATTICED SHELLS USING GENERAL-PURPOSE FE SOFTWARE

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Journal of Structural and Construction Engineering 2023年第809期88卷 1145-1155页

作者： Shiratori, Kan Yamashita, Tetsuo Architecture Program in Graduate School Kogakuin University Japan School of Architecture Kogakuin University Japan

In this paper, a simple and practical method is proposed which enables formfinding analysis of a timber three-way latticed kagome shells and following buckling analysis, using general-purpose FE software without using specialized software for formfinding. In addition, the elastic buckling properties of the kagome shells formed by formfinding are investigated. In-plane shear stiffness of three-way lattices is so high that fixing the intersections does not allow the lattice planes to deform into a shell geometry. Therefore, the formfinding is carried out with virtual slide mechanism at the intersections enables slide of the members along the shell-surface without additional axial stress. © 2023 Architectural Institute of Japan. All rights reserved.

关键词： Buckling

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Cyclic shear tests of steel latticed plates composed of equilateral triangular grids

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Journal of Structural and Construction Engineering 2013年第694期78卷 2153-2161页

作者： Yamashita, Tetsuo Takeuchi, Ryota Shiratori, Kazuki Sato, Harushige School of Architecture Kogakuin University Japan Completed Architecture Program Graduate School Kogakuin University Japan

The present paper demonstrates and discusses a potential of steel latticed plates to use as seismic walls, through experimental study. Cyclic shear load tests of five steel latticed plates, composed of equilateral triangular grids, were conducted to investigate buckling and post-buckling strength and ductility. Three of five plates yield out-of-plane overall buckling and the rest in-plane member buckling as predicted. The buckling and post-buckling strengths can be approximated using the generalized slenderness calculated by linear buckling analysis and its function for inelastic strength, regardless to the buckling mode. Moreover, these latticed plates show good ductility and energy dissipation capacity But a disadvantage that the buckling deformation is too observable is also exposed.

关键词： Ductility

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Study on seismic response of large-span cantilevered roofs considering vibration characteristics of main structures

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Journal of Structural and Construction Engineering 2019年第762期84卷 1073-1080页

作者： Arai, Yudai Yamashita, Testuo Architects and Engineers Architecture Program in Graduate School Kogakuin University Japan School of Architecture Kogakuin University Japan

This study demonstrates a method for seismic response evaluation of large-span cantilevered roofs excited by horizontal seismic input. Firstly we identified the vibration characteristics of an actual cantilevered roof by performing microtremor measurement. By analyzing the data, we found that the cantilevered roof had two major vertical vibration modes, the vibration of cantilever itself and the vibration exited by the sway deformation of the main building. When the main structure and cantilevered roof resonate, the response of cantilever increases. In this paper, the method for specifying that response characteristics of cantilevered roofs is discussed. © 2019 Architectural Institute of Japan. All rights reserved.

关键词： Seismic response

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Elastic buckling behavior of spherical triangular grid shells composed of H-shaped steel on rectangular plan

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Journal of Structural and Construction Engineering 2019年第759期84卷 659-667页

作者： Kageyama, Kai Yamashita, Tetsuo Kanebako Structural Eng Architecture Program in Graduate School Kogakuin University Japan School of Architecture Kogakuin University Japan

Latticed shells made of H-shaped steel have been constructed all over the world. This study investigates elastic buckling of spherical latticed shells made of H-shaped steel. Out-of-plane shell-like buckling and in-plane member buckling dominantly occur in the elastic buckling of rigidly jointed latticed shells. An H-shaped section has strong and weak axes. Since bending stiffness on the strong axis is several times of that on the weak axis, in-plane member buckling is more likely to occur than the buckling of the shells made of pipes. In the present study the latticed shells for study were on the square plan of 20m × 20m. The shells were relatively flat where the rise-span ratios of the two central arcs were between 0.075 and 0.125. In the linear-buckling (eigenvalue) analysis, in-plane member buckling appears in the 1st buckling mode in all the FE models. The depth, area and second moment of inertia on the strong axis were uniformly set to 20cm, 25cm2 and 2000cm4, respectively. On the other hand, the second moment of inertia on the weak axis was parametrically changed so that the higher order linear buckling load where shell-like buckling firstly appeared was 1.5, 2.0 and 2.5 times of the 1st linear member buckling load. In addition, two boundary conditions, pin and roller were assumed since roller is often used in actually constructed shells. The higher order linear buckling loads agreed well with the classical shell-like buckling loads calculated using the continuum analogy. To estimate member buckling load itself, the buckling length is required. The buckling length calculated using the linear buckling analysis, is 0.7 and 0.5 times of the member length for the roller and pin supported shells, respectively. In the pin-supported shells, uniform compression is realized but in the roller-supported shells, compression and tension mix especially on the peripheral where the member buckling occurs. The tensioned members connected to the compressed member interfere the

关键词： Buckling

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Elastic buckling characteristics of single layer latticed shells composed of hexagonal grids

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Journal of Structural and Construction Engineering 2013年第694期78卷 2143-2151页

作者： Yamashita, Tetsuo Senba, Yuta School of Architecture Kogakuin University Japan Maeda Corporation Japan Completed Architecture Program Graduate School Kogakuin University Japan

The present paper demonstrates and discusses elastic bucking characteristics of single layer latticed shells composed of hexagonal grids. A conventional method to calculate linear buckling loads, based on continuum analogy is found to be also effective like other grid patterns. The bucking mode yields long overall buckling waves and is found to be non-extensional. The range of knockdown factors, the ratios of an elastic buckling load where the analysis considers geometric nonlinear effect to the linear buckling, is also investigated by nonlinear FE analysis. The lowest value is reduced to slightly above 0.5 even without geometric imperfection. The knockdown factor and its reduction due to geometric imperfection are mainly affected by the geometry and slenderness. After all, the range of knockdown factors is found to be above 0.5, based on the elastic nonlinear FE analyses in which the maximum imperfection amplitude is set to 1/500 of the span. The knockdown factors are also compared with the calculations by the reduced stiffness buckling theory.

关键词： Buckling

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Earthquake response analysis of steel roof gymnasiums considering nonlinear restoring force characteristics of lower structure and roof bearings

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Journal of Structural and Construction Engineering 2020年第768期85卷 209-218页

作者： Watanabe, Shunya Yamashita, Tetsuo Orimoto Structural Engineers Inc. Japan Architecture Program in Graduate School Kogakuin University Japan School of Architecture Kogakuin University Japan

In the 2011 off the Pacific coast of Tohoku Earthquake, many roof bearings in large span facilities, connecting steel roof to the lower RC frame, suffered severe damages. Based on an experimental study, we constructed a nonlinear restoring force characteristic model of the bearing behavior and conducted a response analysis of a gymnasium structure to find the cause of bearing damage, In addition, we investigated the influence of the weight and stiffness of the RC lower structure and the lengm of the range of motion of the bearmg on the bearmg stress. © 2020 Architectural Institute of Japan. All rights reserved.

关键词： Roofs

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Study on strength and out-of-plane buckling of steel hexagonally latticed plates subjected to cyclic shear deformation

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Journal of Structural and Construction Engineering 2018年第753期83卷 1647-1654页

作者： Yamashita, Tetsuo Oyobe, Hiroyuki Miyazawa, Ryosuke School of Architecture Kogakuin University Japan Completed Master's Program in Graduate School Kogakuin University Japan

This paper finds and discusses the features of buckling and inelastic response on steel hexagonally latticed plates for cyclic shear deformation. Cyclic tests of four steel latticed plates with various hexagonal shapes were performed. The elastic rigidity, yield strength and strain concentration at hinges specified in the tests, can be evaluated theoretically. The various buckling behavior is explained by introducing the generalized slenderness calculated using FE linear buckling analysis. The shear strain at the onset of out-of-plane buckling is approximated by a similar function of generalized slenderness, which was originally proposed for steel panel dampers. © 2018 Architectural Institute of Japan. All rights reserved.

关键词： Shear deformation

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