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1st International Conference of Chemistry 2018, ICCHEM 2018

作者： Febrianto Wiyarsi, A. Partana, C.F. Sulistyo, B. Study Program of Chemistry Education Faculty of Mathematics and Natural Sciences Universitas Negeri Yogyakarta Indonesia Department of Chemistry Education Faculty of Mathematics and Natural Science Universitas Negeri Yogyakarta Indonesia Automotive Engineering Education Department Faculty of Engineering Universitas Negeri Yogyakarta Indonesia

This study aims to analyze the characteristic, feasibility, teachers' and students' responses of Hydrocarbon Chemistry and Petroleum (HCP) module based on the context of vehicle case on automotive engineering. Exploratory mixed method has been employed in this research. The research procedures used four steps including qualitative, development, quantitative, and interpretation step. The instruments used to collect the data consisting the three questionnaires, one open questionnaire to obtain the validation and two close questionnaires to collect the teachers and students' responses toward the HCP module. HCP module based on the context of vehicle case on automotive engineering program was yielded as a result of this reseach. The characteristic of research product was integrating between chemistry and automotive subject based on basic competence of curriculum and integrated by vehicle context in first chapter, concept map, activities, examples, and exercise. A group of experts consisting two lectures were confirmed that the HCP module has a correct chemistry content. A very good category was given as the response of the teacher. Moreover, the students response were very interest toward the HCP module. The students and the tachers could be utilize the HCP module as learning sources reference to gain a succesfull chemistry learning. © Published under licence by IOP Publishing Ltd.

关键词： Vehicles

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Geological hazard potential in Bukit Barisan Selatan National Park (BBSNP) using fault fracture density map and integrated geological aspects

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AIP Conference Proceedings 2023年第1期2482卷

作者： Alviyanda Rezky Naufan Hendrawan Bilal Al Farishi Daniel Radityo Imam A. Sadisun 1Geological Engineering Program Study Institut Teknologi Sumatera Indonesia 2Research and Innovation Center for Geoscience and Mineral Technology Institut Teknologi Sumatera Indonesia 3Faculty of Earth Science and Technology Institut Teknologi Bandung Indonesia

Sumatra Fault as product from tectonic events in Sumatra is the boundary between west and east blocks. Sumatra Fault reactivation could be generated several hazards, especially in Bukit Barisan Selatan National Park (BBSNP). Morphology of Sumatra Fault dominated by hill pattern variations from hill shade form, which should be delineated. The hazard potential has been identified by fault fracture density method combine with geological map and earthquake map. This research used ASTER GDEM and Regional Geology Map as basic data. Lineament interpretation is carried out on drainage map, DEM, and structural geology map. Earthquake data refer by earthquake history occurred near Sumatra Fault and subduction zone in western of Sumatra Island. The earthquake from Sumatra Fault potentially triggers landslide and liquefaction around BBSNP area. There is three regions as having geological hazard potential by Sumatra Fault movement, namely earthquake, landslide and liquefaction. Landslide will be collapsed relatively to the south and affected the main road of BBSNP. Furthermore, in eastern part of Sumatra Fault has liquefaction potential in Semaka and Suoh districts.

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study of Utilization Plastic Waste as Basic Material for Boat Manufacturing Using Eco-green Design Concept

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IOP Conference Series: Materials science and engineering 2021年第1期1125卷

作者： S Noverdo N Iswadi R Reda S Bambang P. Muayyad Studi Program Naval Architecture Faculty of Engineering Universitas Pembangunan Nasional Veteran Jakarta Indonesia Study Program Industrial Engineering Faculty of Engineering Universitas Pembangunan Nasional Veteran Jakarta Indonesia Naval Architecture & Ship Builder-PT Venta Technology Industri Jakarta Indonesia

The plastic waste problem has become a global problem and the effect on the environment is horrible. Almost all countries make an effort to reduce their daily utilization. Environmental organizations and researchers are also performing research to find ways to recycle plastic waste. In this paper introduces the 'Eco-green Design Concept' to utilize plastic waste (type 2) as fishing boat material. This concept will recycle 3 tonnes of plastic waste into the material of a fishing boat. In addition, the implementation element of eco-green design concept (design quality (D), Environmental Friendly (E), Eco-green Material (G)) into the design of fishing vessels has been successful. The concept does not only utilize type 2 plastic waste into the hull of the ship, but the design of the ship is made to have small resistance, good stability and has a large cargo area. And also has a machine that is environmentally friendly and does not cause pollution.

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Reaction pathways design based on the associative property of addition

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AIP Conference Proceedings 2023年第1期2975卷

作者： Fitri N. Febriana Siti N. Nafisah Lusia S. P. Boli Rizka N. Fadilla Wun F. Mark-Lee Ira Puspitasari Febdian Rusydi Research Center for Quantum Engineering Design Faculty of Science and Technology Universitas Airlangga Jl. Mulyorejo Surabaya 60115 Indonesia Theoretical Physics Research Group Department of Physics Faculty of Science and Technology Universitas Airlangga Jl. Mulyorejo Surabaya 60115 Indonesia Department of Chemistry Faculty of Science Universiti Teknologi Malaysia 81310 UTM Johor Bahru Johor Malaysia Information System Study Program Faculty of Science and Technology Universitas Airlangga Jl. Mulyrejo Surabaya 60115 Indonesia

The associative property of addition facilitates the change of the group member. If the group members are molecules, can we apply this property to study a chemical reaction? The aim of this paper is to use the associative property of addition to design reaction pathways of methyl acetate hydrolysis in the acid environment. The reaction is found in Alzheimer’s Disease. We evaluate the designed pathways using activation energy obtained from density functional theory calculation. The results show the associative property of addition can be used to design four reaction pathways of the hydrolysis. The calculations show the acidity significantly affected the activation energy. This result agrees with the common knowledge. Hence, we have demonstrated the usefulness of the associative property of addition in designing chemical reaction pathways.

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Magnetic mineral concentration and microcrystalline characteristics of Fe-rich coastal sand from North Sulawesi

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AIP Conference Proceedings 2023年第1期2694卷

作者： Gerald Tamuntuan Ping A. Angmalisang Adey Tanauma Seni H. Tongkukut Hanny F. Sangian Agnes T. Mandagi Silvia J. Fajar Dolfie P. Pandara Guntur Pasau Ferdy Ferdy As’ari As’ari Department of Physics Sam Ratulangi University Manado 95115 Indonesia Marine Science Study Program Sam Ratulangi University Manado 95115 Indonesia Department of Civil Engineering Sam Ratulangi University Manado 95115 Indonesia Faculty of Mining and Petroleum Engineering Institut Teknologi Bandung Bandung 40132 Indonesia

Magnetic mineral concentration, especially from the iron oxide class, is one of the important indicators in determining the potential iron sand natural resources. In this study, the magnetic measurement as well as X-ray spectroscopy analysis have been carried out in order to determine the concentration and microcrystalline characteristics of iron sand originating from four locations in the coastal area of North Sulawesi which are Lolan, Lalow, Hais, and Minanga. Magnetic properties study through measurement of saturation isothermal remanent magnetization (SIRM) confirmed by oxide composition obtained from X-ray fluorescence (XRF) observation showed that the iron sand sample from Lolan had the highest concentration of iron oxide minerals followed by samples from Hais, Lalow, and Minanga respectively. The percentage of iron oxide at these sites varied between 60.33 – 76.70 wt.%, implying that it was relatively competitive compared to the samples from other localities in Indonesia. Findings related to variations in crystal size and degree of crystallinity are closely related to the source and mechanism of iron sand formation at each study site.

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In silico analysis of tetrahydroxycurcumin compound in tumeric (Curcuma longa) as inhibitor of SARS-CoV-2 virus replication

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AIP Conference Proceedings 2023年第1期2748卷

作者： Mohamad Amin Nanda Hilda Khikmawati Suryadi Suryadi Rifcha Fachrunnisa Ihya Fakhrurizal Amin Dina Maulina Ahya Zhilalikbar Amin Nik Ahmad Nizam Nik Malek Restu Fitriani Department of Biology Faculty of Mathematics and Natural Sciences Universitas Negeri Malang Jl. Semarang No.5 Malang 65145 Indonesia Special Education Department Faculty of Education Universitas Negeri Malang Jl. Semarang No.5 Malang 65145 Indonesia Faculty of Medicine Universitas Indonesia Jakarta Indonesia Biology Education Study Program Faculty of Teacher Training and Education Universitas Lampung Lampung Indonesia Department of Biosciences Faculty of Science Universiti Teknologi Malaysia Johor Malaysia Study Program of Informatics Engineering Faculty of Computer Sciencies Universitas Brawijaya Malang Indonesia Biotechnology Program Faculty of Mathematics and Natural Sciences Universitas Negeri Malang Jl. Semarang No.5 Malang 65145 Indonesia

There are many uses of natural ingredients to find out their potential in overcoming Coronavirus Disease 2019. One of the plants that is often used to treat various diseases, including SARS-Cov2 infection is turmeric. Turmeric contains Tetrahydroxycurcumin compounds. The aim of this research was to study the potential of Tetrahydroxycurcumin in preventing infection with the SARS-CoV-2 virus. The results showed that Tetrahydroxicurcumin has the potential to inhibit Tyrosine protein kinase ABL1, which is a protein that plays a role in the preparation of the cytoskeleton during viral infection. The binding affinity of Tetrahydroxycurcumin for this protein is -8.4 kcal/mol.

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Phage therapy

NATURE REVIEWS METHODS PRIMERS

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NATURE REVIEWS METHODS PRIMERS 2025年第1期5卷 1页

作者： [Anonymous] Human Microbiome Research Program Department of Bacteriology and Immunology Faculty of Medicine University of Helsinki Helsinki Finland European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Non-traditional Antibacterial Therapy (ESGNTA) Basel Switzerland Institute of Biomedical and Oral Research (IBOR) Faculty of Dental Medicine Hebrew University of Jerusaleum Jerusalem Israel The Israeli Phage Center (IPTC) of the Hebrew University and Hadassah Medical Center Jerusalem Israel Department of Clinical Microbiology and Infectious Diseases Hadassah–Hebrew University Medical Center Jerusalem Jerusalem Israel Laboratory of Gene Technology Department of Biosystems KU Leuven Leuven Belgium Leicester Centre for Phage Research Department of Genetics and Genome Biology University of Leicester Leicester UK Center for Evolutionary Hologenomics Globe Institute University of Copenhagen Copenhagen Denmark Centre of Excellence for Omics-Driven Computational Biodiscovery (COMBio) AIMST University Bedong Kedah Malaysia Laboratory of Phage Molecular Biology Institute of Immunology and Experimental Therapy Wrocław Poland Wrocław University of Science and Technology Faculty of Medicine Wrocław Poland Department of Biological Sciences University of Pittsburgh Pittsburgh PA USA Laboratory for Molecular and Cellular Technology Queen Astrid Military Hospital Brussels Belgium Department of Biological and Environmental Science Nanoscience Center University of Jyväskylä Jyväskylä Finland Chemical Engineering Department Loughborough University Loughborough UK

Bacteriophage (phages) are viruses that exclusively use bacterial cells for propagation, killing the bacterial host in the process. In phage therapy, phages are used to reduce bacterial numbers, thereby curing bacterial infections. Although this principle is conceptually straightforward, its practical application faces several hurdles. In this Primer, the practical aspects of phage therapy are outlined. We introduce the microbiological methods used to prepare and characterize phages and elucidate their interactions with bacteria. The discussion covers how the information in complete phage genome sequences is used, along with how RNA sequencing can enhance our understanding of phage biology. Selection parameters for therapeutic phages for clinical applications and key elements in industrial-scale phage production are provided. A summary of clinical trials both past and present, phage administration and dosing issues is analysed, as well as limitations associated with phage therapy and mitigation strategies. Finally, we speculate on the future of phage therapy.

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Interior design study of lecturer rooms at E12 building 2nd floor UNNES – learn from COVID-19 pandemic

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IOP Conference Series: Earth and Environmental science 2021年第1期700卷

作者： A Purnomo Study Program of Architecture Department of Civil Engineering Faculty of Engineering Universitas Negeri Semarang Building E4 Kampus Sekaran Gunungpati Semarang 50229 Indonesia

The covid-19 pandemic case has changed the structure of life in all aspects throughout the world. The field of man-made environment or architecture is no exception. The interior arrangement of a building, as part of the man-made environment, is also affected. The interior design of a building today seems to be obliged to participate in following the standards of new health-protocols in the new normal *** about the interior of the building that has already been utilized? Of course it requires further study to find out whether the interior of a building can be said to be healthy or not. This study aims to examine the interior design of the lecturer room E12 building 2nd floor UNNES in terms of health that is emphasized from the behavior of its users by referring to the situation of the covid-19 pandemic and its future prospects. The research method used is by field observations to search visual data, observing user behavior and textual data. Those who are categorized as users of the lecturer room E12 building 2nd floor UNNES are lecturers from the Department of architecture, students, administrators and guests. The results of this study indicate that based on the pattern of user behavior and associated with the standard requirements of space, area, volume of space, material and infrastructure conditions, interior design of lecturer room E12 building 2nd floor UNNES, is included in healthy category, although there are several minor corrections that can be included as suggestions for improvement in order to adjust to the new normal era during the covid-19 pandemic period and thereafter.

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Patchouli oil analysis of chemical components using FT-IR and GCMS method

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AIP Conference Proceedings 2023年第1期2738卷

作者： Hermin Pancasakti Kusumaningrum Rizqi Sa’adatun Ni’mah Yunita Nurlindasari Annisa Imrani Sadam Arrois Eko Purnomo Fa’ireza Rafli Arfiansyah Erni Setyowati Bambang Dwi Loka Biotechnology Study Program Biology Department Faculty of Science and Mathematics Diponegoro University Jl. Prof. Soedharto SH. Tembalang Semarang 50275 Indonesia Department of Chemical Engineering Faculty of Engineering Diponegoro University Jl. Prof. Soedharto SH. Tembalang Semarang 50275 Indonesia Architecture Department Faculty of Engineering Diponegoro University Jl. Prof. Soedharto SH. Tembalang Semarang 50275 Indonesia Food Technology Department Faculty of Animal and Agricultural Sciences Diponegoro University Jl. Prof. Soedharto SH. Tembalang Semarang 50275 Indonesia

Patchouli (Pogostemon cablin Benth.) is a plant that produces essential oils to be used for cosmetics, soap, antiseptic, perfume, pharmaceutical, insecticide and aromatherapy industries. One of the products produced from the patchouli plant is patchouli oil. This study aims to determine the content of chemical compounds contained in the essential oil of patchouli using the GC-MS analysis method to determine the molecular structure of the compound and separate the fractions in patchouli oil. Another method is the FT-IR analysis method to identify the functional groups contained in patchouli oil. The chemical properties of patchouli oil from the Blado area, Batang Indonesia, are traditionally distilled from fresh patchouli leaves and stems. The results of the GCMS analysis showed that there were 10 compounds with 4 peaks of dominant components which were the constituents of patchouli essential oil, namely Patchouli Alcohol (39.46 %), Delta-Guaiene (21.51%), Alpha Guaiene (20.13%), Alpha-patchoulena (9.01%). In the FTIR results carried out in the range of 4000-450 cm-1, various functional groups such as C=C, –CH2, C-H, C=O, O-H, C-O, =C-H, and N-H. This shows that patchouli oil is rich in alcohol, aromatics, and aldehydes.

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Antioxidant compounds of leaves and seeds extracts of Parkia Speciosa overcome ferroptosis

Food Chemistry Advances

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Food Chemistry Advances 2025年 7卷

作者： Nopiyanti, Elsa Safithri, Mega Trivadila Sahidin Kuspradini, Harlinda Earnestly, Femi Hirata, Yoko Takemori, Hiroshi Batubara, Irmanida Department of Chemistry Chemistry Post-graduate Program Bogor Agricultural University West Java Bogor Indonesia Department of Biochemistry Chemistry Post-graduate Program Bogor Agricultural University West Java Bogor Indonesia Department of Pharmacy Faculty of Pharmacy Universitas Halu Oleo Kendari Indonesia Faculty of Forestry Universitas Mulawarman Samarinda East Kalimantan Indonesia Faculty of Pharmacy Muhammadiyah University of Sumatera Barat West Sumatera Padang Indonesia Life Science Research Center Institute for Advanced Study Gifu University Gifu Japan Department of Chemistry and Biomolecular Science Faculty of Engineering Gifu University Gifu Japan Tropical Biopharmaca Research Center IPB University West Java Bogor Indonesia

Parkia speciosa seeds, a widely consumed plant in Southeast Asia, are known for their rich bioactive compounds with potential health benefits. This study investigates the antioxidant properties of ethanol extracts from P. speciosa leaves (PSL) and seeds (PSS) to combat oxidative stress. Antioxidant activity was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays, revealing that PSL exhibited higher antioxidant potential than PSS, with values of 14.34 ± 0.02 and 19.39 ± 0.04 μg ascorbic acid equivalent (AAE)/g extract, respectively. The ethanol extracts of PSL and PSS significantly protected HT22 cells from erastin-induced ferroptotic cell death and activated the antioxidant response element (ARE) pathway, enhancing endogenous antioxidant defense mechanisms. Furthermore, in silico molecular docking analysis identified 7,7′-Dihydroxy-5′‑methoxy-2′,2′-dimethyl-4-oxo-3′,4′-dihydro-2′H,4H-3,6′-bichromen-5-yl hexopyranosiduronic acid as a promising bioactive compound with strong binding affinities to oxidative stress-related receptors (5i6x, 6cm4, 2f8a, 8bxn, and 8ivr). These findings suggest that P. speciosa ethanol extract, particularly from its leaves, exhibits strong antioxidant and neuroprotective properties, supporting its potential application as a natural therapeutic agent for oxidative stress-related disorders. © 2025 The Authors

关键词： 7,7′-Dihydroxy-5′-methoxy-2′2′-dimethyl-4-oxo-3′4′-dihydro-2′H 4H-3 6′-bichromen-5-yl hexopyranosiduronic acid antioxidant response element Ferroptosis, P. speciosa HT22 cells

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