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arXiv 2024年

作者： de la Rosa, Ezequiel Reyes, Mauricio Liew, Sook-Lei Hutton, Alexandre Wiest, Roland Kaesmacher, Johannes Hanning, Uta Hakim, Arsany Zubal, Richard Valenzuela, Waldo Robben, David Sima, Diana M. Anania, Vincenzo Brys, Arne Meakin, James A. Mickan, Anne Broocks, Gabriel Heitkamp, Christian Gao, Shengbo Liang, Kongming Zhang, Ziji Siddiquee, Md Mahfuzur Rahman Myronenko, Andriy Ashtari, Pooya Van Huffel, Sabine Jeong, Hyun-Su Yoon, Chi-Ho Kim, Chulhong Huo, Jiayu Ourselin, Sebastien Sparks, Rachel Clèrigues, Albert Oliver, Arnau Lladó, Xavier Chalcroft, Liam Pappas, Ioannis Bertels, Jeroen Heylen, Ewout Moreau, Juliette Hatami, Nima Frindel, Carole Qayyum, Abdul Mazher, Moona Puig, Domenec Lin, Shao-Chieh Juan, Chun-Jung Hu, Tianxi Boone, Lyndon Goubran, Maged Liu, Yi-Jui Wegener, Susanne Kofler, Florian Ezhov, Ivan Shit, Suprosanna Hernandez Petzsche, Moritz R. Menze, Bjoern Kirschke, Jan S. Wiestler, Benedikt Department of Quantitative Biomedicine University of Zurich Zurich Switzerland Department of Informatics Technical University Munich Germany Icometrix Leuven Belgium ARTORG Center for Biomedical Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Switzerland University of Bern Bern Switzerland Chan Division of Occupational Science and Occupational Therapy University of Southern California Los AngelesCA United States Stevens Neuroimaging and Informatics Institute Department of Neurology Keck School of Medicine University of Southern California United States University Institute of Diagnostic and Interventional Neuroradiology Inselspital Bern Switzerland University Institute of Diagnostic and Interventional Neuroradiology University Hospital Bern Inselspital University of Bern Bern Switzerland Department of Diagnostic and Interventional neuroradiology University Medical Center Hamburg-Eppendorf Hamburg Germany Department of Medical Imaging Radboud University Medical Center Institute for Health Sciences Nijmegen Netherlands Deepwise AI Lab Beijing China Beijing University of Posts and Telecommunications Bejing China School of Computing and Augmented Intelligence Arizona State University TempeAZ United States NVIDIA Santa ClaraCA United States STADIUS Center for Dynamical Systems Signal Processing and Data Analytics KU Leuven Leuven Belgium Pohang Korea Republic of School of Biomedical Engineering & Imaging Sciences King’s College London United Kingdom Institute of Computer Vision and Robotics University of Girona Spain Wellcome Centre for Human Neuroimaging University College London London United Kingdom Laboratory of Neuro Imaging Stevens Institute for Neuroimaging and Informatics Keck School of Medicine University of Southern California Los Angeles United States KU Leuven Leuven Belgium CREATIS Université Lyon1 CNRS UMR5220 INSERM U1206 INSA-Lyon Villeurbanne696

Diffusion-weighted MRI (DWI) is essential for stroke diagnosis, treatment decisions, and prognosis. However, image and disease variability hinder the development of generalizable AI algorithms with clinical value. We address this gap by presenting a novel ensemble algorithm derived from the 2022 Ischemic Stroke Lesion Segmentation (ISLES) challenge. ISLES’22 provided 400 patient scans with ischemic stroke from various medical centers, facilitating the development of a wide range of cutting-edge segmentation algorithms by the research community. By assessing them against a hidden test set, we identified strengths, weaknesses, and potential biases. Through collaboration with leading teams, we combined top-performing algorithms into an ensemble model that overcomes the limitations of individual solutions. Our ensemble model combines the individual algorithms’ strengths and achieved superior ischemic lesion detection and segmentation accuracy (median Dice score: 0.82, median lesion-wise F1 score: 0.86) on our internal test set compared to individual algorithms. This accuracy generalized well across diverse image and disease variables. Furthermore, the model excelled in extracting clinical biomarkers like lesion types and affected vascular territories. Notably, in a Turing-like test, neuroradiologists consistently preferred the algorithm’s segmentations over manual expert efforts, highlighting increased comprehensiveness and precision. Validation using a real-world external dataset (N=1686) confirmed the model’s generalizability (median Dice score: 0.82, median lesion-wise F1 score: 0.86). The algorithm’s outputs also demonstrated strong correlations with clinical scores (admission NIHSS and 90-day mRS) on par with or exceeding expert-derived results, underlining its clinical relevance. This study offers two key findings. First, we present an ensemble algorithm that detects and segments ischemic stroke lesions on DWI across diverse scenarios on par with expert (neuro)rad

关键词： Diagnosis

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Scalable block-diagonal locality-constrained projective dictionary learning

arXiv

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arXiv 2019年

作者： Zhang, Zhao Jiang, Weiming Zhang, Zheng Li, Sheng Liu, Guangcan Qin, Jie School of Computer Science School of Artificial Intelligence Hefei University of Technology China School of Computer Science and Technology Soochow University China School of Information Technology and Electrical Engineering University of Queensland Australia Department of Computer Science University of Georgia United States School of Information and Control Nanjing University of Information Science and Technology China Computer Vision Laboratory ETH Zurich Switzerland

We propose a novel structured discriminative blockdiagonal dictionary learning method, referred to as scalable Locality-Constrained Projective Dictionary Learning (LC-PDL), for efficient representation and classification. To improve the scalability by saving both training and testing time, our LC-PDL aims at learning a structured discriminative dictionary and a block-diagonal representation without using costly l0/l1-norm. Besides, it avoids extra time-consuming sparse reconstruction process with the well-trained dictionary for new sample as many existing models. More importantly, LC-PDL avoids using the complementary data matrix to learn the sub-dictionary over each class. To enhance the performance, we incorporate a locality constraint of atoms into the DL procedures to keep local information and obtain the codes of samples over each class separately. A block-diagonal discriminative approximation term is also derived to learn a discriminative projection to bridge data with their codes by extracting the special block-diagonal features from data, which can ensure the approximate coefficients to associate with its label information clearly. Then, a robust multiclass classifier is trained over extracted block-diagonal codes for accurate label predictions. Experimental results verify the effectiveness of our algorithm. Copyright © 2019, The Authors. All rights reserved.

关键词： Machine learning

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Cooperative intelligence for Autonomous Driving

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ZTE Communications 2019年第2期17卷 44-50页

作者： CHENG Xiang DUAN Dongliang YANG Liuqing ZHENG Nanning State Key Laboratory of Advanced Optical Communication Systems and Networks School of Electronics Engineering and Computer SciencePeking UniversityBeijing 100871China Department of Electrical and Computer Engineering University of WyomingLaramieWY 82071USA Department of Electrical and Computer Engineering Colorado State UniversityFort CollinsCO 80523USA Institute of Artificial Intelligence and Robotics Xi’an Jiaotong UniversityXi’anShaanxi 710049China

Autonomous driving is an emerging technology attracting interests from various sectors in recent *** of existing work treats autonomous vehicles as isolated individuals and has focused on developing separate intelligent *** this paper,we attempt to exploit the connectivity among vehicles and propose a systematic framework to develop autonomous driving *** first introduce a general hierarchical information fusion framework for cooperative sensing to obtain global situational awareness for *** this,a cooperative intelligence framework is proposed for autonomous driving *** general framework can guide the development of data collection,sharing and processing strategies to realize different intelligent functions in autonomous driving.

关键词： autonomous driving cooperative intelligence information fusion vehicular communications and networking

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Corrigendum to "PSFHS challenge report: pubic symphysis and fetal head segmentation from intrapartum ultrasound images" [Medical Image Analysis 99 (2025),103353]

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Medical image analysis 2025年 104卷 103651页

作者： Jieyun Bai Zihao Zhou Zhanhong Ou Gregor Koehler Raphael Stock Klaus Maier-Hein Marawan Elbatel Robert Martí Xiaomeng Li Yaoyang Qiu Panjie Gou Gongping Chen Lei Zhao Jianxun Zhang Yu Dai Fangyijie Wang Guénolé Silvestre Kathleen Curran Hongkun Sun Jing Xu Pengzhou Cai Lu Jiang Libin Lan Dong Ni Mei Zhong Gaowen Chen Víctor M Campello Yaosheng Lu Karim Lekadir Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Informatization Jinan University Guangzhou China Auckland Bioengineering Institute The University of Auckland Auckland New Zealand. Electronic address: jbai996@aucklanduni.ac.nz. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Informatization Jinan University Guangzhou China. Division of Medical Image Computing German Cancer Research Center (DKFZ) Heidelberg Germany. Department of Computer Science and Engineering The Chinese University of Hong Kong China. Computer Vision and Robotics Group University of Girona Girona Spain. Canon Medical Systems (China) Co. LTD Beijing China. College of Artificial Intelligence Nankai University Tianjin China. College of Computer Science and Electronic Engineering Hunan University Changsha China. School of Medicine University College Dublin Dublin Ireland. School of Computer Science University College Dublin Dublin Ireland. School of Statistics & Mathematics Zhejiang Gongshang University Hangzhou China. School of Computer Science & Engineering Chongqing University of Technology Chongqing China. National-Regional Key Technology Engineering Laboratory for Medical Ultrasound & Guangdong Provincial Key Laboratory of Biomedical Measurements and Ultrasound Imaging & School of Biomedical Engineering Health Science Center Shenzhen University Shenzhen China. NanFang Hospital of Southern Medical University Guangzhou China. Zhujiang Hospital of Southern Medical University Guangzhou China. Departament de Matemàtiques i Informàtica Universitat de Barcelona Barcelona Spain. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Informatization Jinan University Guangzhou China. Electronic address: tluys@***. Departament de Matemàtiques i Informàtica Universitat de Barcelona Barcelona Spain Institució Catalana de Recerca i Estudis Avançats (ICREA) Barcelona Spain.

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Understanding metric-related pitfalls in image analysis validation

arXiv

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arXiv 2023年

作者： Reinke, Annika Tizabi, Minu D. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Kavur, A. Emre Rädsch, Tim Sudre, Carole H. Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Buettner, Florian Cardoso, M. Jorge Cheplygina, Veronika Chen, Jianxu Christodoulou, Evangelia Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian van Ginneken, Bram Glocker, Ben Godau, Patrick Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Isensee, Fabian Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kleesiek, Jens Kofler, Florian Kooi, Thijs Kopp-Schneider, Annette Kozubek, Michal Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rafelski, Susanne M. Rajpoot, Nasir Reyes, Mauricio Riegler, Michael A. Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. van Calster, Ben Varoquaux, Gaël Yaniv, Ziv R. Jäger, Paul F. Maier-Hein, Lena Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany NCT Heidelberg A Partnership Between DKFZ University Medical Center Heidelberg Germany Heidelberg Division of Medical Image Computing Germany Heidelberg Division of Intelligent Medical Systems Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montreal Canada Division of Computational Pathology Dept of Pathology & Laboratory Medicine Indiana University School of Medicine IU Health Information and Translational Sciences Building Indianapolis United States University of Pennsylvania Richards Medical Research Laboratories FL7 PhiladelphiaPA United States Department of Digital Medical Technologies Holon Institute of Technology Holon Israel European Federation for Medical Informatics Le Mont-sur-Lausanne Switzerland Center for Processing Speech and Images Department of Electrical Engineering KU Leuven Leuven Belgium partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt Marburg Germany Heidelberg Germany Goethe University Frankfurt Department of Medicine Germany Goethe University Frankfurt Department of Informatics Germany and Frankfurt Cancer Insititute Germany Department of Computer Science IT University of Copenhagen Copenhagen Denmark Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Dortmund Germany Imaging Platform Broad Institute of MIT and Harvard CambridgeMA United States Centre for Statistics in Medicine University of Oxford Oxford United Kingdom Center for Biomedical In

Validation metrics are key for tracking scientific progress and bridging the current chasm between artificial intelligence (AI) research and its translation into practice. However, increasing evidence shows that particularly in image analysis, metrics are often chosen inadequately. While taking into account the individual strengths, weaknesses, and limitations of validation metrics is a critical prerequisite to making educated choices, the relevant knowledge is currently scattered and poorly accessible to individual researchers. Based on a multi-stage Delphi process conducted by a multidisciplinary expert consortium as well as extensive community feedback, the present work provides the first reliable and comprehensive common point of access to information on pitfalls related to validation metrics in image analysis. While focused on biomedical image analysis, the addressed pitfalls generalize across application domains and are categorized according to a newly created, domain-agnostic taxonomy. The work serves to enhance global comprehension of a key topic in image analysis validation. © 2023, CC BY.

关键词： computer vision

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A framework and resource for global collaboration in non-human primate neuroscience

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Current Research in Neurobiology 2023年 4卷 100079页

作者： Hartig, Renée Klink, P. Christiaan Polyakova, Zlata Dehaqani, Mohammad-Reza A. Bondar, Igor Merchant, Hugo Vanduffel, Wim Roe, Anna Wang Nambu, Atsushi Thirumala, M. Shmuel, Amir Kapoor, Vishal Gothard, Katalin M. Evrard, Henry C. Basso, Michele A. Petkov, Christopher I. Mitchell, Anna S. Max Planck Institute for Biological Cybernetics Max-Planck-Ring 11 Tübingen 72076 Germany Functional and Comparative Neuroanatomy Laboratory Werner Reichardt Centre for Integrative Neuroscience Eberhard Karls University of Tübingen Otfried-Müller-Straße 25 Tübingen 72076 Germany Department of Psychiatry and Psychotherapy University Medical Center Johannes Gutenberg-University Mainz 55131 Germany Nathan S. Kline Institute for Psychiatric Research Center for Biomedical Imaging and Neuromodulation Orangeburg New York 10962 United States Department of Vision and Cognition Netherlands Institute for Neuroscience Royal Netherlands Academy of Arts and Sciences Meibergdreef 47 Amsterdam 1105 BA Netherlands Laboratory of Visual Brain Therapy Sorbonne Université Institut National de la Santé et de la Recherche Médicale Centre National de la Recherche Scientifique Institut de la Vision Paris F-75012 France Experimental Psychology Helmholtz institute Utrecht University Heidelberglaan 1 Utrecht 3584 CS Netherlands Center for Human Nature Artificial Intelligence and Neuroscience Hokkaido University Sapporo 060-0812 Japan School of Electrical and Computer Engineering College of Engineering University of Tehran Tehran Iran School of Cognitive Sciences Institute for Research in Fundamental Sciences (IPM) Tehran Iran Department of Brain and Cognitive Sciences Cell Science Research Center Royan Institute for Stem Cell Biology and Technology ACECR Tehran Iran Institute of Higher Nervous Activity and Neurophysiology Russian Academy of Sciences Moscow Russian Federation Institute of Neurobiology Universidad Nacional Autónoma de México Campus Juriquilla Department of Neurophysiology Querétaro 76230 Mexico Laboratory for Neuro- and Psychophysiology Department of Neurosciences KU Leuven Medical School Leuven 3000 Belgium Leuven Brain Institute KU Leuven Leuven 3000 Belgium Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital Charlest

As science and technology evolve, there is an increasing need for promotion of international scientific exchange. Collaborations, while offering substantial opportunities for scientists and benefit to society, also present challenges for those working with animal models, such as non-human primates (NHPs). Diversity in regulation of animal research is sometimes mistaken for the absence of common international welfare standards. Here, the ethical and regulatory protocols for 13 countries that have guidelines in place for biomedical research involving NHPs were assessed with a focus on neuroscience. Review of the variability and similarity in trans-national NHP welfare regulations extended to countries in Asia, Europe and North America. A tabulated resource was established to advance solution-oriented discussions and scientific collaborations across borders. Our aim is to better inform the public and other stakeholders. Through cooperative efforts to identify and analyze information with reference to evidence-based discussion, the proposed key ingredients may help to shape and support a more informed, open framework. This framework and resource can be expanded further for biomedical research in other countries. © 2023

关键词： Ethics Macaque Marmoset Regulations Requirements Welfare

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Online multi-object tracking and segmentation with GMPHD filter and mask-based affinity fusion

arXiv

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arXiv 2020年

作者： Song, Young-Min Yoon, Young-Chul Yoon, Kwangjin Jeon, Moongu Lee, Seong-Whan Pedrycz, Witold The School of Electrical Engineering and Computer Science Gwangju Institute of Technology Gwangju61005 Korea Republic of The Robotics Laboratory Hyundai Motor Company Gyeonggi-do 16082 Korea Republic of SI Analytics Co. Ltd. Daejeon34051 Korea Republic of The Department of Artificial Intelligence Korea University Seoul02841 Korea Republic of The Department of Brain and Cognitive Engineering Korea University Seoul02841 Korea Republic of The Department of Electrical and Computer Engineering University of Alberta EdmontonABT6R 2H5 Canada The Department of Electrical and Computer Engineering Faculty of Engineering King Abdulaziz University Jeddah21589 Saudi Arabia The Systems Research Institute Polish Academy of Sciences Warsaw01-447 Poland

In this paper, we propose a highly practical fully online multi-object tracking and segmentation (MOTS) method that uses instance segmentation results as an input. The proposed method is based on the Gaussian mixture probability hypothesis density (GMPHD) filter, a hierarchical data association (HDA), and a mask-based affinity fusion (MAF) model to achieve high-performance online tracking. The HDA consists of two associations: segment-to-track and track-to-track associations. One affinity, for position and motion, is computed by using the GMPHD filter, and the other affinity, for appearance is computed by using the responses from a single object tracker such as a kernalized correlation filter. These two affinities are simply fused by using a score-level fusion method such as min-max normalization referred to as MAF. In addition, to reduce the number of false positive segments, we adopt mask IoU-based merging (mask merging). The proposed MOTS framework with the key modules: HDA, MAF, and mask merging, is easily extensible to simultaneously track multiple types of objects with CPU-only execution in parallel processing. In addition, the developed framework only requires simple parameter tuning unlike many existing MOTS methods that need intensive hyperparameter optimization. In the experiments on the two popular MOTS datasets, the key modules show some improvements. For instance, ID-switch decreases by more than half compared to a baseline method in the training sets. In conclusion, our tracker achieves state-of-the-art MOTS performance in the test sets. Copyright © 2020, The Authors. All rights reserved.

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NTIRE 2021 Challenge on Image Deblurring

arXiv

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arXiv 2021年

作者： Nah, Seungjun Son, Sanghyun Lee, Suyoung Timofte, Radu Lee, Kyoung Mu Chen, Liangyu Zhang, Jie Lu, Xin Chu, Xiaojie Chen, Chengpeng Xiong, Zhiwei Xu, Ruikang Xiao, Zeyu Huang, Jie Zhang, Yueyi Xi, Si Wei, Jia Bai, Haoran Cheng, Songsheng Wei, Hao Sun, Long Tang, Jinhui Pan, Jinshan Lee, Donghyeon Lee, Chulhee Kim, Taesung Wang, Xiaobing Zhang, Dafeng Pan, Zhihong Lin, Tianwei Wu, Wenhao He, Dongliang Li, Baopu Li, Boyun Xi, Teng Zhang, Gang Liu, Jingtuo Han, Junyu Ding, Errui Tao, Guangpin Chu, Wenqing Cao, Yun Luo, Donghao Tai, Ying Lu, Tong Wang, Chengjie Li, Jilin Huang, Feiyue Chen, Hanting Chen, Shuaijun Guo, Tianyu Wang, Yunhe Zamir, Syed Waqas Arora, Aditya Khan, Salman Hayat, Munawar Khan, Fahad Shahbaz Shao, Ling Zuo, Yushen Ou, Yimin Chai, Yuanjun Shi, Lei Liu, Shuai Lei, Lei Feng, Chaoyu Zeng, Kai Yao, Yuying Liu, Xinran Zhang, Zhizhou Huang, Huacheng Zhang, Yunchen Jiang, Mingchao Zou, Wenbin Miao, Si Kim, Yangwoo Sun, Yuejin Deng, Senyou Ren, Wenqi Cao, Xiaochun Wang, Tao Suin, Maitreya Rajagopalan, A.N. Duong, Vinh Van Nguyen, Thuc Huu Yim, Jonghoon Jeon, Byeungwoo Li, Ru Xie, Junwei Han, Jong-Wook Choi, Jun-Ho Kim, Jun-Hyuk Lee, Jong-Seok Zhang, Jiaxin Peng, Fan Svitov, David Pakulich, Dmitry Kim, Jaeyeob Jeong, Jechang Department of ECE ASRI SNU Korea Republic of Computer Vision Lab ETH Zurich Switzerland University of Science and Technology of China China Megvii China Fudan University China Peking University China Netease Games AI Lab Nanjing University of Science and Technology China Guilin University of Electronic Technology China Samsung Electronics Co. Ltd Sunmoon University Asan Korea Republic of Samsung Research China Beijing China Baidu Research United States Department of Computer Vision Technology Baidu Inc China Fudan University China Megvii China Nanjing University China Tencent Noah's Ark Lab Huawei Technologies Co. Ltd Inception Institute of Artificial Intelligence Tsinghua University Beijing China North China University of Technology China Xiaomi South China University of Technology China Lab of Image Science and Technology Southeast University China China Design Group Co. Ltd China JOYY AI GROUP Fujian Normal University China Shanghai Advanced Research Institute Chinese Academy of Sciences China Institute of Information Engineering Chinese Academy of Sciences China Huawei Noah's Ark Lab Indian Institute of Technology Madras India Department of ECE Sungkyunkwan University Korea Republic of Fuzhou University China Imperial Vision Co. Ltd School of Integrated Technology Yonsei University Korea Republic of Expasoft LLC Institute of Automation and Electrometry The SB RAS Image Communication & Signal Processing Laboratory Hanyang University Korea Republic of

Motion blur is a common photography artifact in dynamic environments that typically comes jointly with the other types of degradation. This paper reviews the NTIRE 2021 Challenge on Image Deblurring. In this challenge report, we describe the challenge specifics and the evaluation results from the 2 competition tracks with the proposed solutions. While both the tracks aim to recover a high-quality clean image from a blurry image, different artifacts are jointly involved. In track 1, the blurry images are in a low resolution while track 2 images are compressed in JPEG format. In each competition, there were 338 and 238 registered participants and in the final testing phase, 18 and 17 teams competed. The winning methods demonstrate the state-of-the-art performance on the image deblurring task with the jointly combined artifacts. © 2021, CC BY-NC-ND.

关键词： Image enhancement

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Metrics Reloaded: Recommendations for image analysis validation

arXiv

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arXiv 2022年

作者： Maier-Hein, Lena Reinke, Annika Godau, Patrick Tizabi, Minu D. Buettner, Florian Christodoulou, Evangelia Glocker, Ben Isensee, Fabian Kleesiek, Jens Kozubek, Michal Reyes, Mauricio Riegler, Michael A. Wiesenfarth, Manuel Emre Kavur, A. Sudre, Carole H. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Rädsch, Tim Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Jorge Cardoso, M. Cheplygina, Veronika Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian Ginneken, Bram Van Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kofler, Florian Kopp-Schneider, Annette Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rajpoot, Nasir Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Smeden, Maarten Van Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben Van Varoquaux, Gaël Jäger, Paul F. Heidelberg Division of Intelligent Medical Systems and HI Helmholtz Imaging Germany Faculty of Mathematics and Computer Science and Medical Faculty Heidelberg University Heidelberg Germany NCT Heidelberg a partnership between DKFZ University Medical Center Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt-Marburg Germany Heidelberg Goethe University Frankfurt Germany Department of Medicine Goethe University Frankfurt Germany Department of Informatics Frankfurt Cancer Insititute Germany Department of Computing Imperial College London London United Kingdom Heidelberg Division of Medical Image Computing and HI Applied Computer Vision Lab Germany Institute for AI in Medicine University Medicine Essen Essen Germany Centre for Biomedical Image Analysis Faculty of Informatics Masaryk University Brno Czech Republic ARTORG Center for Biomedical Engineering Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Bern Switzerland Simula Metropolitan Center for Digital Engineering Oslo Norway UiT The Arctic University of Norway Romsø Norway Heidelberg Division of Biostatistics Germany Heidelberg Division of Intelligent Medical Systems Division of Medical Image Computing HI Applied Computer Vision Lab Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Heidelberg Division of Medical Image Computing Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain interest, thus failing to adequately measure scientific progress and hindering translation of ML techniques into practice. To overcome this, we created Metrics Reloaded, a comprehensive framework guiding researchers in the problem-aware selection of metrics. It was developed by a large international consortium in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint – a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output. Based on the problem fingerprint, users are guided through the process of choosing and applying appropriate validation metrics while being made aware of potential pitfalls. Metrics Reloaded targets image analysis problems that can be interpreted as a classification task at image, object or pixel level, namely image-level classification, object detection, semantic segmentation, and instance segmentation tasks. To improve the user experience, we implemented the framework in the Metrics Reloaded online tool. Following the convergence of ML methodology across application domains, Metrics Reloaded fosters the convergence of validation methodology. Its applicability is demonstrated for various biomedical use cases. © 2022, CC BY.

关键词： Semantic Segmentation

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The medical segmentation decathlon

arXiv

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arXiv 2021年

作者： Antonelli, Michela Reinke, Annika Bakas, Spyridon Farahani, Keyvan Kopp-Schneider, Annette Landman, Bennett A. Litjens, Geert Menze, Bjoern Ronneberger, Olaf Summers, Ronald M. van Ginneken, Bram Bilello, Michel Bilic, Patrick Christ, Patrick F. Do, Richard K.G. Gollub, Marc J. Heckers, Stephan H. Huisman, Henkjan Jarnagin, William R. McHugo, Maureen K. Napel, Sandy Golia Pernicka, Jennifer S. Rhode, Kawal Tobon-Gomez, Catalina Vorontsov, Eugene Hulsmon, Hankan Meakin, James A. Ourselin, Sebastien Wiesenfarth, Manuel Arbeláez, Pablo Bae, Byeonguk Chen, Sihong Daza, Laura Feng, Jianjiang He, Baochun Isensee, Fabian Ji, Yuanfeng Jia, Fucang Kim, Namkug Kim, Ildoo Merhof, Dorit Pai, Akshay Park, Beomhee Perslev, Mathias Rezaiifar, Ramin Rippel, Oliver Sarasua, Ignacio Shen, Wei Son, Jaemin Wachinger, Christian Wang, Liansheng Wang, Yan Xia, Yingda Xu, Daguang Xu, Zhanwei Zheng, Yefeng Simpson, Amber L. Maier-Hein, Lena Cardoso, M. Jorge School of Biomedical Engineering & Imaging Sciences King’s College London London United Kingdom Heidelberg Germany Heidelberg Germany Faculty of Mathematics and Computer Science University of Heidelberg Heidelberg Germany University of Pennsylvania PhiladelphiaPA United States BethesdaMD United States Heidelberg Germany Electrical Engineering and Computer Science Vanderbilt University NashvilleTN United States Radboud University Medical Center Radboud Institute for Health Sciences Nijmegen Netherlands Quantitative Biomedicine University of Zurich Zurich Switzerland DeepMind London United Kingdom School of Computing Department of Biomedical and Molecular Sciences Queen’s University KingstonON Canada Department of Surgery Memorial Sloan Kettering Cancer Center New YorkNY United States BethesdaMD United States Department of Informatics Technische Universität München Germany Department of Radiology Memorial Sloan Kettering Cancer Center New YorkNY United States Department of Psychiatry & Behavioral Sciences Vanderbilt University Medical Center NashvilleTN United States Department of Radiology Stanford University StanfordCA United States Department of Computer Science and Software Engineering École Polytechnique de Montréal Department of Radiology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Medical Faculty University of Heidelberg Heidelberg Germany VUNO Inc. Seoul Korea Republic of Universidad de los Andes Colombia Department of Automation Tsinghua University Beijing China Heidelberg Germany Department of Computer Science Xiamen University Xiamen361005 China Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China Kakao Brain Korea Republic of Institute of Imaging & Computer Vision RWTH Aachen University Aachen Germany Cere

International challenges have become the de facto standard for comparative assessment of image analysis algorithms given a specific task. Segmentation is so far the most widely investigated medical image processing task, but the various segmentation challenges have typically been organized in isolation, such that algorithm development was driven by the need to tackle a single specific clinical problem. We hypothesized that a method capable of performing well on multiple tasks will generalize well to a previously unseen task and potentially outperform a custom-designed solution. To investigate the hypothesis, we organized the Medical Segmentation Decathlon (MSD)—a biomedical image analysis challenge, in which algorithms compete in a multitude of both tasks and modalities. The underlying data set was designed to explore the axis of difficulties typically encountered when dealing with medical images, such as small data sets, unbalanced labels, multi-site data and small objects. The MSD challenge confirmed that algorithms with a consistent good performance on a set of tasks preserved their good average performance on a different set of previously unseen tasks. Moreover, by monitoring the MSD winner for two years, we found that this algorithm continued generalizing well to a wide range of other clinical problems, further confirming our hypothesis. Three main conclusions can be drawn from this study: (1) state-of-the-art image segmentation algorithms are mature, accurate, and generalize well when retrained on unseen tasks;(2) consistent algorithmic performance across multiple tasks is a strong surrogate of algorithmic generalizability;(3) the training of accurate AI segmentation models is now commoditized to non AI *** Codes 68T07. © 2021, CC BY-NC-SA.

关键词： Image segmentation

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