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An Exploratory Computational Approach for Elucidating a Nonstructural Protein Interaction in Dengue Virus 2

Procedia computer science 2024年 245卷 470-479页

作者： Alam Ahmad Hidayat Rudi Nirwantono Bens Pardamean Mathematics Department School of Computer Science Bina Nusantara University Indonesia 11480 Biotechnology Department Faculty of Engineering Bina Nusantara University Indonesia 11480 Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia 11480 Computer Science Department BINUS Graduate Program Bina Nusantara University Jakarta Indonesia 11480

As the dengue infection still impacts hundreds of millions of people globally, unprecedented efforts in dengue drug development have been more progressive in recent decades. Computational methods provide a fast, sustainable, and efficient screening of active compounds and newly created drug molecules, including those specifically targeting nonstructural proteins (NS) of dengue viruses. In this work, protein modeling for the NS proteins of DENV-2/16681 strain was performed using a template-based homology modeling for the NS3 protein and an Artificial Intelligence (AI)-based prediction via AlphaFold for the NS4B protein. Moreover, the protein-protein interaction between the two structures was predicted using the HADDOCK server, which employs information about active and passive residues of the interaction interface to guide the docking process. After the modeling and its respective refinement process, the predicted structures of NS3 and NS4B improved their steric clashing scoring from MolProbity assessment. The refined models were then docked, and the resulting docking pose was analyzed to extract the interacting residues based on the polar contacts within the interface of the two proteins. Our result presents a preliminary study to create a dataset related to in silico molecular interactions of the NS3-NS4B interaction of different DENV types. It is helpful for building a computational pipeline for elucidating protein-ligand problems in dengue drug screenings.

关键词： bioinformatics computational biology dengue protein docking structural biology

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Security Risks and Best Practices for Blockchain and Smart Contracts: A Systematic Literature Review

Security Risks and Best Practices for Blockchain and Smart C...

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International Conference on Information Management and Technology (ICIMTech)

作者： Semi Yulianto Harco Leslie Hendric Spits Warnars Harjanto Prabowo Meyliana Achmad Nizar Hidayanto Computer Science Department BINUS Graduate Program - Doctor of Computer Science Bina Nusantara University Jakarta Indonesia Management Department BINUS Business School Undergraduate Program Bina Nusantara University Jakarta Indonesia Information Systems Department School of Information Systems Bina Nusantara University Jakarta Indonesia Faculty of Computer Science Universitas Indonesia Depok Indonesia

The rise of blockchain technology and smart contracts has brought widespread attention due to their capacity to transform multiple industrial sectors through decentralized, transparent, secure transactions. However, despite their promise to revolutionize various fields worldwide, lingering concerns regarding security risks impede their adoption rate. Addressing these concerns is crucial now more than ever; therefore, we conducted a comprehensive literature review within our study's scope that focused on published papers between 2014-2023 centered around security risks concerning blockchain and smart contracts. Our systematic approach using the PRISMA checklist analyzed nine categorized research model-based primary studies while recognizing vulnerabilities in smart contract development and providing best practices to mitigate such issues. These findings benefit both researchers and practitioners as they showcase how acknowledging these vulnerabilities can further develop into exploring more significant aspects of blockchain technology's security issues and smart contract development processes. Our study contributes significantly by expanding knowledge in this field while providing novel insights valuable for individuals involved in designing or implementing blockchain technologies.

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Analysis of the Effect of Internet of Things Implementation on the Taxation Area in Indonesia

Analysis of the Effect of Internet of Things Implementation ...

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Advancement in Data science, E-learning and Information Systems (ICADEIS), International Conference on

作者： Wahyu Sardjono Widhilaga Gia Perdana Achmad Cholidin Information Systems Management Department BINUS Graduate Program Master of Information Systems Management Bina Nusantara University Jakarta Indonesia Post Graduate Program of Management Science State University of Jakarta Jakarta Indonesia Law Study Program Faculty of Law University of Muhammadiyah Jakarta Indonesia

Technology in the tax field is evolving by the minute. Digital technology has many implications for development in various fields. One of them is the field of economics. One of the latest technologies is the Internet of Things, which has attracted the attention of various organizations and governments, more precisely the tax authorities. This research tries to illustrate the impact of the Internet of Things on taxation. The researcher used qualitative research with literature survey methods. Data were collected from various journals, media publications, articles, and previous research papers. The study's findings indicated that the Internet of Things (IoT) is crucial to the development of control technologies. This supports the Director General of Taxes’ (DGT) goal of using big data analytics to optimize the potential of digital taxes through his two mechanisms: predictive analytics and tax ranking.

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The Country's Implementation and Adoption of Standardized Health Terminologies to Promote Interoperability: A Systematic Literature Review

The Country's Implementation and Adoption of Standardized He...

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International Conference on Information Management and Technology (ICIMTech)

作者： Taufiq Sitompul Harco Leslie Hendric Spits Warnars Meyliana Achmad Nizar Hidayanto Harjanto Prabowo Computer Science Department BINUS Graduate Program - Doctor of Computer Science Bina Nusantara University Jakarta Indonesia Information Systems Department School of Information Systems Bina Nusantara University Jakarta Indonesia Faculty of Computer Science Universitas Indonesia Depok Indonesia Management Department BINUS Business School Undergraduate Program Bina Nusantara University Jakarta Indonesia

Modern healthcare systems demand comprehensive information systems but face obstacles during adoption. Organizational and structural complexity, especially decentralized systems, challenges the integrated management and sharing of data across information systems. Interoperability is critical to address these issues effectively in heterogeneous and distributed environments. However, different medical terminology hinders interoperability within health information systems. To address this, a systematic literature review examined various medical terminology standards for national interoperability. From 790 articles, 12 were selected according to PRISMA guidelines with inclusion and exclusion criteria. Standard health terminology is critical to achieving interoperability, and many countries have adopted it, although some have required adaptation to accommodate local contexts. Data models, governance, and maintenance of standards are equally important in achieving national interoperability. In addition, standardized health terminology promotes consistency and uniformity in terminology, which is beneficial for decision-making by stakeholders in the health system.

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Semantic Literature Review on Non-Fungible Token: Expansion Area of Usage & Trends

Semantic Literature Review on Non-Fungible Token: Expansion ...

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International Conference on Information Management and Technology (ICIMTech)

作者： Gede Indra Raditya Martha Harco Leslie Hendric Spits Warnars Harjanto Prabowo Meyliana Achmad Nizar Hidayanto Computer Science Department BINUS Graduate Program - Doctor of Computer Science Bina Nusantara University Jakarta Indonesia Management Department BINUS Business School Undergraduate Program Bina Nusantara University Jakarta Indonesia Information System Department School of Information Systems Bina Nusantara University Jakarta Indonesia Faculty of Computer Science University of Indonesia Depok Indonesia

Blockchain, Metaverse & NFT are technologies that were booming during the Pandemic. As a derivative product of blockchain, the Non-Fungible Token (NFT) is one of the technologies that has attracted the most interest from investors and the public because of its potential benefits and has always been closely associated with the Metaverse as a main purposes research of the NFTs. This paper is to explore the possibilities and provide an overview of the current use of NFT technology so that it can provide insight for further research & gap with the big picture that it is trying to present in this paper. However, after exploring further related to NFT in this research, it was found that the problem that most people are trying to solve through NFT is related to the topic of Decentralization & Web3 not as a Metaverse main backbone.

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Combining DistilBERT and LSTM to Enhanced Detection of Depression in Social Media Text

Combining DistilBERT and LSTM to Enhanced Detection of Depre...

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International Conference on Information Management and Technology (ICIMTech)

作者： Felix Indra Kurniadi Ni Luh Putu Satyaning Pradnya Paramita Erna Fransisca Angela Sihotang Maria Susan Anggreainy Rongfang Zhan Computer Science Department School of Computer Science Bina Nusantara University Jakarta Indonesia Statistics Department School of Computer Science Bina Nusantara University Jakarta Indonesia Computer Science Department BINUS Graduate Program - Doctor of Computer Science Bina Nusantara University Jakarta Indonesia Department of Rehabilitation and Health Service School of Computer Science University of North Texas United States of America

ISBN: (数字)9798350390025

ISBN: (纸本)9798350390032

Depression affects a significant number of people, and it has a significant impact not only on their lives but also on society as a whole. In light of this, we require more advanced methods that are capable of locating individuals who are depressed in a timely and accurate manner. This research investigates the effectiveness of Long Short-Term Mem- ory (LSTM) networks used in conjunction with DistilBERT, a small transformer-based model, in identifying indications of melancholy in posts made on social networking platforms. The text was cleaned up using a dataset that was obtained from Reddit, and then we used the mixed DistilBERT+LSTM model to evaluate how well it performed in comparison to the DistilBERT model by itself. The findings that we obtained indicate that both approaches produce results that are comparable but not flawless, with only slight variations in terms of accuracy, precision, recall, and F1 scores. The fact that this is the case demonstrates that there are issues with optimizing the model and displaying the data.

关键词： Micromechanical devices Accuracy Social networking (online) Mood Mental health Depression Transformers Data models Information management Long short term memory

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Twitter-based text classification using svm for weather information system 6

Twitter-based text classification using svm for weather info...

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6th International Conference on Information Management and Technology, ICIMTech 2021

作者： Purwandari, Kartika Rahutomo, Reza Sigalingging, Join W. C. Ajy Kusuma, Mahisa Prasetyo, Aji Pardamean, Bens Research Center Bina Nusantara University Bioinformatics and Data Science Jakarta11480 Indonesia BMKG Meteorological Climatological and Geophysical Agency Database Center Division Jakarta10720 Indonesia Bina Nusantara University BINUS Graduate Program - Master of Computer Science Computer Science Department Jakarta11480 Indonesia

ISBN: (纸本)9781665449373

The popularity of social media amplified the amount of text data that is used to enrich text classification research with machine learning approach. The modernization in weather information system is needed to produce real-time weather information using the involvement of Twitter users. GetOldTweets was used to cover data acquisition from Twitter. Support Vector Machine (SVM) was deployed as a machine learning model for text classification. The result was delivered in Esri Maps features. It facilitated a social sensing for Indonesia weather information system by using Twitter posts from Indonesian users with 93% accuracy. © 2021 IEEE.

关键词： Data acquisition

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Predicting User Preferences with Neural Network Learning to Rank Method 5

Predicting User Preferences with Neural Network Learning to ...

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5th IEEE International Conference on Information Technology, Information Systems and Electrical Engineering, ICITISEE 2021

作者： Qomariyah, Nunung Nurul Fajar, Ahmad Nurul Bina Nusantara University Faculty Of Computing And Media Computer Science Department Jakarta11480 Indonesia Bina Nusantara University BINUS Graduate Program-Master Of Information Systems Management Information Systems Management Department Jakarta11480 Indonesia

ISBN: (纸本)9781665401968

User preference learning has been around for many years. This is a common problem arise in e-commerce system, where the companies need to understand their customers in order to sell the correct products to their target customers. The user preference is also needed in the movie domain area, as the film companies who produce the movie also need to understand how the customers value their movie products, whether the market like it or not. This can help them to predict the best components for the future movie. In order to produce the recommendation to the customer, we can show a list of item in a correct order, sorted from the most relevant/the most liked one to the most irrelevant item. In this paper, we utilize the Learning to Rank (LTR) approach from information retrieval domain area to learn the user preference in recommender system domain. We applied LTR with pairwise approach from the two most popular algorithms in this area, i.e. RankNet and LambdaRank, on 25, 345 user ratings from 5, 000 movie dataset and evaluate both algorithms. We used a Neural Network architecture as the learning mechanism. We also measuring the speed performance of the two algorithms. © 2021 IEEE.

关键词： Sales

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Design and Implementation of Business Intelligence Dashboard for Project Control at the Port Harbor-Company 12th

Design and Implementation of Business Intelligence Dashboard...

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12th Asian Conference on Intelligent Information and Database Systems, ACIIDS 2020

作者： Lumban Gaol, Ford Syahir, Arsyan Matsuo, Tokuro Computer Science Department BINUS Graduate Program – Doctor of Computer Science Bina Nusantara University Jakarta Indonesia Computer Science Department BINUS Graduate Program – Master of Information System Bina Nusantara University Jakarta Indonesia Advanced Institute of Industry Technology Tokyo Japan

ISBN: (纸本)9789811533792

This study aims to assist resource management and the project controller at Port Harbor Company. Port Harbor Company is an IT Consulting. Problems that often occur in IT Consulting are related to the project cost, resource management and control of each project. Problems that occur at the Port Harbor Company are poor resource management, spending costs that exceed a predetermined budget and how to see the status of ongoing projects. Using Business Intelligence and the dashboard as a front end will help the project controller and resource management manage resources, manage project costs and monitor ongoing projects. In this study, the development and implementation of Business Intelligence and dashboards using the ASAP method are expected to be more structured and can solve the Port Harbor Company problem. © 2020, Springer Nature Singapore Pte Ltd.

关键词： Project management

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Text-based Depression Detection on Social Media Posts: A Systematic Literature Review

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Procedia computer science 2021年 179卷 582-589页

作者： David William Derwin Suhartono Computer Science Department BINUS Graduate Program – Master of Computer Science Bina Nusantara University Jakarta Indonesia 11480 Computer Science Department School of Computer Science Bina Nusantara University Jakarta 11480 Indonesia

Due to the huge increase of awareness of mental health well-being, the detection of mental illness itself is starting to become a huge concern. Many psychiatrists found difficulties in identifying the existence of mental illness in a patient because of the complicated nature of each mental disorder, thus making it hard to give the appropriate treatment to the patient before it’s too late. However, due to the integration of social media into people’s daily life, this create an environment that may provide additional information regarding the mental disorder a patient bear. This study has been undertaken as a Systematic Literature Review (SLR), which is defined as a process of identifying, assessing, and interpreting the available resources to provide answers for a set of research questions. Analysis is made to answer questions regarding text-based mental illness detection based on the social media activity of people with mental disorders, and reveals that it indeed is possible to do early detection of depression on social due to the existence of a particular characteristics in the way these subjects use their social media. This SLR found that from the small amount of research using text-based approach, most studies use deep learning models such as RNN on the early detection of depression cases due to the limitation of data availability. However, this study will look to find method that may prove to be more effective.

关键词： Linguistic analysis Natural language processing Depression detection Social media

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