检索结果-内蒙古大学图书馆

Chinese Materials Conference, 2018

作者： Hu, Chunyan Kong, Zhiqiang Liu, Xinling Tao, Chunhu Beijing Institute of Aeronautical Materials Beijing100095 China Beijing Key Laboratory of Aeronautical Materials Testing and Evaluation Beijing100095 China Aviation key Laboratory of Science and Technology on Materials Testing and Evaluation Beijing100095 China

ISBN: (纸本)9783035713848

With the development of aero-engine with high specific flux, high thrus-weight ratio, and high turbine inlet temperature, it is an effective way to improve the cooling efficiency by designing dense gas film holes on the blade surface of the turbine blades, especially at the intake side. However, the introduction of gas film holes destroys the geometrical integrity of the blade structure, resulting in a multiaxial high stress state of the blade material around the small holes, which seriously affects the strength and life of the cooling blades. In addition, the geometry design of the gas film holes also directly affects the temperature and the oxidation rate of the turbine rotor blades. In this paper, the researches on the mechanical properties and oxidative damage of the gas film holes at home and abroad in recent years have been systematically introduced. The effects of gas film holes on the durability and fatigue properties, the high temperature oxidation behavior of single crystal superalloys, and the thin-walled effect of oxidative damage of gas film holes have been systematically described. © 2019 Trans Tech Publications, Switzerland.

关键词： Turbomachine blades

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Comparison of Proton Shower Developments in the BGO Calorimeter of the Dark Matter Particle Explorer between GEANT4 and FLUKA Simulations

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Chinese Physics Letters 2020年第11期37卷 114-120页

作者： Wei Jiang Chuan Yue Ming-Yang Cui Xiang Li Qiang Yuan Francesca Alemanno Paolo Bernardini Giovanni Catanzani Zhan-Fang Chen Ivan De Mitri Tie-Kuang Dong Giacinto Donvito David Francois Droz Piergiorgio Fusco Fabio Gargano Dong-Ya Guo Dimitrios Kyratzis Shi-Jun Lei Yang Liu Francesco Loparco Peng-Xiong Ma Giovanni Marsella Mario Nicola Mazziotta Xu Pan Wen-Xi Peng Antonio Surdo Andrii Tykhonov Yi-Yeng Wei Yu-Hong Yu Jing-Jing Zang Ya-Peng Zhang Yong-Jie Zhang Yun-Long Zhang Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China Gran Sasso Science Institute(GSSI) Viale F.Crispi 7I-67100L'AquilaItaly Istituto Nazionale di Fisica Nucleare Laboratori Nazionali del Gran SassoVia G.Acitelli 22I-67100AssergiL'AquilaItaly Dipartimento di Matematica e Fisica E.De Giorgi Universitàdel SalentoI-73100 LecceItaly Istituto Nazionale di Fisica Nucleare(INFN)-Sezione di Lecce I-73100 LecceItaly INFN Section of Perugia I-06100 PerugiaItaly University of Perugia I-06100 PerugiaItaly Istituto Nazionale di Fisica Nucleare(INFN)-Sezione di Bari I-70125BariItaly Department of Nuclear and Particle Physics University of GenevaCH-1211Switzerland Dipartimento Interateneo“M.Merlin”dell'Universitàdegli Studi di Bari e del Politecnico di Bari I-70125BariItaly Dipartimento di Fisica e Chimica“E.Segrè” via delle Scienze Edificio 17UniversitàDegli Studi di PalermoI-90128PalermoItaly Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China

The DArk Matter Particle Explorer(DAMPE)is a satellite-borne detector for high-energy cosmic rays and *** fully understand the detector performance and obtain reliable physical results,extensive simulations of the detector are *** simulations are particularly important for the data analysis of cosmic ray nuclei,which relies closely on the hadronic and nuclear interactions of particles in the detector *** adopted simulation softwares include the GEANT4 and FLUKA,both of which have been implemented for the DAMPE simulation *** we describe the simulation tool of DAMPE and compare the results of proton shower properties in the calorimeter from the two simulation *** a comparison gives an estimate of the most significant uncertainties of our proton spectral analysis.

关键词： material. GEANT4 calorimeter

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Dense attention fluid network for salient object detection in optical remote sensing images

arXiv

引用

arXiv 2020年

作者： Zhang, Qijian Cong, Runmin Li, Chongyi Cheng, Ming-Ming Fang, Yuming Cao, Xiaochun Zhao, Yao Kwong, Sam The Department of Computer Science City University of Hong Kong Hong Kong The Institute of Information Science Beijing Jiaotong University Beijing100044 China The Beijing Key Laboratory of Advanced Information Science and Network Technology Beijing100044 China The School of Computer Science and Engineering Nanyang Technological University Singapore The College of Computer Science Nankai University Tianjin300071 China School of Information Technology Jiangxi University of Finance and Economics NanchangJiangxi330032 China The State Key Laboratory of Information Security Institute of Information Engineering Chinese Academy of Sciences Beijing100093 China Cyberspace Security Research Center Peng Cheng Laboratory Shenzhen518055 China School of Cyber Security University of Chinese Academy of Sciences Beijing100049 China The City University of Hong Kong Shenzhen Research Institute Shenzhen51800 China

Despite the remarkable advances in visual saliency analysis for natural scene images (NSIs), salient object detection (SOD) for optical remote sensing images (RSIs) still remains an open and challenging problem. In this paper, we propose an end-to-end Dense Attention Fluid Network (DAFNet) for SOD in optical RSIs. A Global Context-aware Attention (GCA) module is proposed to adaptively capture long-range semantic context relationships, and is further embedded in a Dense Attention Fluid (DAF) structure that enables shallow attention cues flow into deep layers to guide the generation of high-level feature attention maps. Specifically, the GCA module is composed of two key components, where the global feature aggregation module achieves mutual reinforcement of salient feature embeddings from any two spatial locations, and the cascaded pyramid attention module tackles the scale variation issue by building up a cascaded pyramid framework to progressively refine the attention map in a coarse-to-fine manner. In addition, we construct a new and challenging optical RSI dataset for SOD that contains 2,000 images with pixel-wise saliency annotations, which is currently the largest publicly available benchmark. Extensive experiments demonstrate that our proposed DAFNet significantly outperforms the existing state-of-the-art SOD competitors. https://***/ rmcong/DAFNet_TIP20 © 2020, CC BY-NC-SA.

关键词： Object detection

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Bi-affinity Electrolyte Optimizing High-Voltage Lithium-Rich Manganese Oxide Battery via Interface Modulation Strategy

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Angewandte Chemie 2023年第30期135卷

作者： Xuedi Yuan Dr. Tao Dong Jiaxin Liu Dr. Yingyue Cui Haotian Dong Dr. Du Yuan Prof. Haitao Zhang Beijing Key Laboratory of Ionic Liquids Clean Process Institute of Process Engineering Chinese Academy of Sciences Beijing 100190 P. R. China School of Henan Institute of Advanced Technology Zhengzhou University Zhengzhou 450002 P. R. China Contribution: Data curation (lead) Formal analysis (lead) Methodology (lead) Writing - original draft (lead) Contribution: Methodology (supporting) Supervision (lead) Contribution: Methodology (supporting) College of Materials Science and Engineering Changsha University of Science and Technology 960 2nd Section Changsha Hunan 410004 P. R. China Henan Key Laboratory of Energy Storage Materials and Processes Zhengzhou Institute of Emerging Industrial Technology Zhengzhou 450003 P. R. China Contribution: Conceptualization (lead) Funding acquisition (lead) Resources (lead) Supervision (lead) Writing - review & editing (lead)

The practical implementation of high-voltage lithium-rich manganese oxide (LRMO) cathode is limited by the unanticipated electrolyte decomposition and dissolution of transition metal ions. The present study proposes a bi-affinity electrolyte formulation, wherein the sulfonyl group of ethyl vinyl sulfone (EVS) imparts a highly adsorptive nature to LRMO, while fluoroethylene carbonate (FEC) exhibits a reductive nature towards Li metal. This interface modulation strategy involves the synergistic use of EVS and FEC as additives to form robust interphase layers on the electrode. As-formed S-endorsed but LiF-assisted configuration cathode electrolyte interphase with a more dominant −SO 2 − component may promote the interface transport kinetics and prevent the dissolution of transition metal ions. Furthermore, the incorporation of S component into the solid electrolyte interphase and the reduction of its poorly conducting component can effectively inhibit the growth of lithium dendrites. Therefore, a 4.8 V LRMO/Li cell with optimized electrolyte may demonstrate a remarkable retention capacity of 97 % even after undergoing 300 cycles at 1 C.

关键词： Bi-Affinity Electrolyte Ethyl Vinyl Sulfone Fluoroethylene Carbonate Interphase Modulation Strategy Lithium Rich Manganese Oxide Cathode

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Geochemical Characteristics of Wuyang Siliceous Rocks in the Southern Margin of North China Craton and its Constraint on the Formation Environment of BIF of Tieshanmiao Formation

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Acta Geologica Sinica(English Edition) 2019年第6期93卷 1738-1754页

作者： LI Hongzhong HE Junguo LIANG Jin YANG Fei ZHAI Mingguo ZHANG Lianchang Voudouris PANAGIOTIS Guangdong Provincal Key Lab of Geodynamics and Geohazards Guangdong Provincal Key Laboratory of Geological processes and mineral Resource SurveySchool of Earth Sciences and EngineeringSun Yat-sen UniversityGuangzhou 510275China Key Laboratory of Mineral Resource Institute of Geology and GeophysicsChinese Academy of ScienceBeijing 100029China School of Civil and Transportation Engineering Guangdong University of TechnologyGuangzhou 510006China Key Laboratory of Submarine Geosciences Ministry of Natural ResourcesHangzhou 30012China Second Institute of Oceanography Ministry of Natural ResourcesHangzhou 310012China Department of Mineralogy-Petrology National and Kapodistrian University of AthensAthens 15784Greece

Precambrian banded iron formation(BIF)is one of the most important mineral resources in China,mostly abundant in the North China Craton(NCC)with relatively less common in South *** the BIF and siliceous rocks both originated from chemical deposition,the syngenetic BIF and Siliceous rocks can help evaluate their environment of *** examine here the mineralogy and geochemistry of siliceous rocks associated with the Tieshanmiao Formation BIF,aiming to decipher the conditions of formation of both BIF and Siliceous rocks in the Wuyang area in the *** of the geochemical characteristics of whole rock shows that the Si O2 content of the siliceous rock ranges from 90.11%to 94.85%and is relatively high *** element contents of Ba and U are also high,the Ba/Sr ratio ranges from 3.89 to 25.28 and the U/Th ratio ranges from 0.09 to ***,theΣREE value of rare earth elements ranges from 57.03 ppm to 152.59 ppm,and these indexes all indicate that siliceous rock resulted from hydrothermal *** of Al2 O3-Si O2,Si O2/(K2 O+Na2 O)-Mn O2/Ti O2 and Mn-10×(Cu+Co+Ni)-Fe in discrimination diagrams also verify this ***,both the Mg O content,ranging from 0.16 to 0.32,and the Fe/Ti ratio,ranging from 2.50 to 9.72,suggest that terrigenous material was added during the depositional *** and trace element parameters of siliceous rock,such as the Al/(A1+Fe+Mn)ratio(from 0.81 to 0.93),Mn O/Ti O2(from 0.00 to 0.17),Al/(Al+Fe)(from 0.82 to 0.93),Sc/Th ratio(from 0.21 to 0.50),U/Th(from 0.09 to 0.20),(La/Yb)N(from 0.83 to 3.04),and the(La/Ce)N(from 0.01 to 0.02)all imply that the siliceous rock formed in a continental *** addition,the Sr/Ba ratio from 0.08 to 0.26,theδCe value from 0.31 to 0.90,and theδEu value from 0.14 to 0.58,all indicate that the siliceous rock was formed at a relatively deeper water depth and under weak hydrodynamic *** rock and BIF formed in the same geological setting,with t

关键词： siliceous rock banded iron formation geochemistry Tieshanmiao Formation Wuyang area

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Flavor Physics at CEPC: a General Perspective

arXiv

引用

arXiv 2024年

作者： Ai, Xiaocong Altmannshofer, Wolfgang Athron, Peter Bai, Xiaozhi Calibbi, Lorenzo Cao, Lu Che, Yuzhi Chen, Chunhui Chen, Ji-Yuan Chen, Long Chen, Mingshui Chen, Shanzhen Chen, Xuan Cheng, Shan Chiang, Cheng-Wei Crivellin, Andreas Cui, Hanhua Deschamps, Olivier Descotes-Genon, Sébastien Du, Xiaokang Fang, Shuangshi Gao, Yu Geng, Li-Sheng Goldenzweig, Pablo Gu, Jiayin Guo, Feng-Kun Guo, Yuchen Guo, Zhi-Hui Han, Tao He, Hong-Jian He, Jibo He, Miao Huang, Yanping Isidori, Gino Ji, Quan Jiang, Jianfeng Jiang, Xu-Hui Kamenik, Jernej F. Kwok, Tsz Hong Li, Gang Li, Geng Li, Haibo Li, Haitao Li, Hengne Li, Honglei Li, Liang Li, Lingfeng Li, Qiang Li, Shu Li, Xiaomei Li, Xin-Qiang Li, Yiming Li, Yubo Li, Yuji Li, Zhao Liang, Hao Liang, Zhijun Liao, Libo Ligeti, Zoltan Liu, Jia Liu, Jianbei Liu, Tao Liu, Yi Liu, Yong Liu, Zhen Lou, Xinchou Lu, Peng-Cheng Lusiani, Alberto Ma, Hong-Hao Ma, Kai Mao, Yaxian Marzocca, David Niu, Juan-Juan Prell, Soeren Qi, Huirong Qian, Sen Qian, Zhuoni Qin, Qin Rock, Ariel Rosner, Jonathan L. Ruan, Manqi Shao, Dingyu Shen, Chengping Shen, Xiaoyan Shi, Haoyu Shi, Liaoshan Si, Zong-Guo Sierra, Cristian Song, Huayang Su, Shufang Su, Wei Tammaro, Michele Wang, En Wang, Fei Wang, Hengyu Wang, Jian Wang, Jianchun Wang, Kun Wang, Lian-Tao Wang, Wei Wang, Xiaolong Wang, Xiaoping Wang, Yadi Wang, Yifang Wang, Yuexin Wu, Xing-Gang Wu, Yongcheng Xiao, Rui-Qing Xie, Ke-Pan Xie, Yuehong Xu, Zijun Yang, Haijun Yang, Hongtao Yang, Lin Yang, Shuo Yin, Zhongbao Yu, Fusheng Yuan, Changzheng Yuan, Xing-Bo Yuan, Xuhao Yue, Chongxing Zhan, Xi-Jie Zhang, Kaili Zhang, Liming Zhang, Xiaoming Zhang, Yang Zhang, Yanxi Zhang, Yongchao Zhang, Yu Zhang, Zhen-Hua Zhang, Zhong Zhao, Mingrui Zhao, Qiang Zheng, Xu-Chang Zheng, Yangheng Zhou, Chen Zhu, Pengxuan Zhu, Yongfeng Zuo, Xunwu Zupan, Jure School of Physics Zhengzhou University Zhengzhou450001 China Department of Physics Santa Cruz Institute for Particle Physics University of California Santa Cruz95064 United States Department of Physics Institute of Theoretical Physics Nanjing Normal University Nanjing210023 China University of Science and Technology of China Hefei230026 China School of Physics Nankai University Tianjin300071 China Fudan University Shanghai200438 China Hamburg22607 Germany Institute of High Energy Physics Chinese Academy of Sciences Beijing100049 China Beijing100049 China Department of Physics and Astronomy Iowa State University AmesIA50011-1026 United States School of Physics Shandong University Shandong Jinan250100 China School of Physics and Electronics Hunan University Changsha410082 China Department of Physics Center for Theoretical Physics National Taiwan University Taipei10617 Taiwan VilligenCH-5232 Switzerland Physik-Institut Universität Zürich ZürichCH-8057 Switzerland Université Clermont Auvergne CNRS IN2P3 LPC Clermont-Ferrand63178 France Université Paris-Saclay CNRS IN2P3 IJCLab Orsay91405 France Institute of Physics Henan Academy of Sciences Zhengzhou450046 China School of Physics Beihang University Beijing100191 China Karlsruhe76131 Germany Department of Physics Fudan University Shanghai200438 China Center for Field Theory and Particle Physics Fudan University Shanghai200438 China Fudan University Shanghai200438 China CAS Key Laboratory of Theoretical Physics Institute of Theoretical Physics Chinese Academy of Sciences Beijing100190 China Peng Huanwu Collaborative Center for Research and Education Beihang University Beijing100191 China Department of Physics Liaoning Normal University Dalian116029 China Center for Theoretical and Experimental High Energy Physics Liaoning Normal University Dalian116029 China Department of Physics Hebei Key Laboratory of Photophysics Research and Application Hebei Norma

We discuss the landscape of flavor physics at the Circular Electron-Positron Collider (CEPC), based on the nominal luminosity outlined in its Technical Design Report. The CEPC is designed to operate in multiple modes to address a variety of tasks. At the Z pole, the expected production of 4 Tera Z bosons will provide unique and highly precise measurements of Z boson couplings, while the substantial number of boosted heavy-flavored quarks and leptons produced in clean Z decays will facilitate investigations into their flavor physics with unprecedented precision. We investigate the prospects of measuring various physics benchmarks and discuss their implications for particle theories and phenomenological models. Our studies indicate that, with its highlighted advantages and anticipated excellent detector performance, the CEPC can explore beauty and τ physics in ways that are superior to or complementary with the Belle II and Large-Hadron-Collider-beauty experiments, potentially enabling the detection of new physics at energy scales of 10 TeV and above. This potential also extends to the observation of yet-to-be-discovered rare and exotic processes, as well as testing fundamental principles such as lepton flavor universality, lepton and baryon number conservation, etc., making the CEPC a vibrant platform for flavor physics research. The WW threshold scan, Higgs-factory operation and top-pair productions of the CEPC further enhance its merits in this regard, especially for measuring the Cabibbo-Kobayashi-Maskawa matrix elements, and Flavor-Changing-Neutral-Current physics of Higgs boson and top quarks. We outline the requirements for detector performance and considerations for future development to achieve the anticipated scientific goals. The role of machine learning for innovative detector design and advanced reconstruction algorithms is also stressed. The CEPC flavor physics program not only develops new capabilities for exploring flavor physics beyond existing projec

关键词： Bosons

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Positive-parity linear-chain molecular band in 16C

arXiv

引用

arXiv 2020年

作者： Liu, Y. Ye, Y.L. Lou, J.L. Yang, X.F. Baba, T. Kimura, M. Yang, B. Li, Z.H. Li, Q.T. Xu, J.Y. Ge, Y.C. Hua, H. Wang, J.S. Yang, Y.Y.Y. Ma, P. Bai, Z. Hu, Q. Liu, W. Ma, K. Tao, L.C. Jiang, Y. Hu, L.Y. Zang, H.L. Feng, J. Wu, H.Y. Han, J.X. Bai, S.W. Li, G. Yu, H.Z. Huang, S.W. Chen, Z.Q. Sun, X.H. Li, J.J. Tan, Z.W. Gao, Z.H. Duan, F.F. Tan, J.H. Sun, S.Q. Song, Y.S. School of Physics State Key Laboratory of Nuclear Physics and Technology Peking University Beijing100871 China Kitami Institute of Technology Kitami090-8507 Japan Department of Physics Hokkaido University Sapporo060-0810 Japan School of Science Huzhou University Huzhou313000 China Institute of Modern Physics Chinese Academy of Science Lanzhou730000 China Fundamental Science on Nuclear Safety and Simulation Technology Laboratory Harbin Engineering University Harbin150001 China

An inelastic excitation and cluster-decay experiment 2H(16C, 4He + 12Be or 6He + 10Be)2H was carried out to investigate the linear-chain clustering structure in neutron-rich 16C. For the first time, decay-paths from the 16C resonances to various states of the final nuclei were determined, thanks to the well-resolved Q-value spectra obtained from the three-fold coincident measurement. The close-threshold resonance at 16.5 MeV is assigned as the Jπ= 0+ band head of the predicted positive-parity linear-chain molecular band with (3/2-π)2(1/2-δ)2configuration, according to the associated angular correlation and decay analysis. Other members of this band were found at 17.3, 19.4, and 21.6 MeV based on their selective decay properties, being consistent with the theoretical predictions. Another intriguing high-lying state was observed at 27.2 MeV which decays almost exclusively to 6He + 10Be(∼ 6 MeV) final channel, corresponding well to another predicted linear- chain structure with the pure -bond configuration. Copyright © 2020, The Authors. All rights reserved.

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Influences of preparation techniques on glass-forming ability of Fe-P-B-Si-C amorphous alloys

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Journal of Iron and Steel Research International 2018年第6期25卷 674-679页

作者： Ji-jun Zhang Ya-qiang Dong Lu-yang Bie Qiang Li Jia-wei Li Xin-min Wang Key Laboratory of Magnetic Materials and Devices NingboInstitute of Materials Technology and Engineering ChineseAcademy of Sciences Ningbo 315201 Zhejiang China Zhejiang Province Key Laboratory of Magnetic Materials andApplication Technology Ningbo Institute of MaterialsTechnology and Engineering Chinese Academy of SciencesNingbo 315201 Zhejiang China University of Chinese Academy of Sciences Beijing 100049China School of Physics Science and Technology XinjiangUniversity Urumqi 830046 Xinjiang China

It has been widely accepted that the ultrafast cooling rate is required for the glass formation of amorphous alloys. Here, the larger glass-forming ability （GFA） of Fe76P5（B0.5Si0.3C0.2）19 amorphous alloy was achieved by water quenching at lower cooling rate under argon atmosphere. Cylindrical rods with diameters of 1-2 mm were prepared by water quenching without flux treatment, Cu-mold injection casting, and Cu-mold suction casting, respectively. The influences of the preparation techniques with different cooling rates on GFA, thermal property, and nucleation/growth behavior were examined. The critical diameter of the Fe76P5（B0.5Si0.3C0.2）19 amorphous alloys is 1.7 mm for water quenching while smaller than 1.0 mm for injection casting. Microstructure analysis indicates that the crystallization and solidification processes are quite different between the water-quenched and the injection-cast rods. These findings could deepen fun-damental understanding on the relationship between the cooling rate, techniques, and GFA of Fe-based amorphous alloys.

关键词： Fe-based amorphous alloy Preparation technique Glass-forming ability Crystallization behavior

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Phosphate limitation increases coenzyme Q10 production in industrial Rhodobacter sphaeroides HY01

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Synthetic and Systems Biotechnology 2019年第4期4卷 212-219页

作者： Lu Zhang Leshi Liu Ke-Feng Wang Lan Xu Liming Zhou Weishan Wang Chuan Li Zheng Xu Tong Shi Haihong Chen Yuanhang Li Hui Xu XiuLiang Yang Zhichun Zhu Biqin Chen Dan Li Guanghuang Zhan Si-Liang Zhang Li-Xin Zhang Gao-Yi Tan State Key Laboratory of Bioreactor Engineering(SKLBE) And School of BiotechnologyEast China University of Science and Technology(ECUST)No.130 Meilong RoadShanghai200237China State Key Laboratory of Microbial Resources and CAS Key Laboratory of Pathogenic Microbiology and Immunology Institute of MicrobiologyChinese Academy of Sciences(CAS)No.1 Beichen West RoadBeijing100101China Institute of Applied Ecology Chinese Academy of SciencesShenyang110016China Shandong Jincheng Bio-Pharmaceutical Co. LtdNo.117 Qixing River RoadZibo255130China Inner Mongolia Kingdomway Pharmaceutical Co. LtdTuoketuo Power Industrial ParkHohhot010206China Department of Biology Beijing Institute of EducationBeijing 100044China

Coenzyme Q10(CoQ10)is an important component of the respiratory chain in humans and some *** a high-value-added nutraceutical antioxidant,CoQ10 has excellent capacity to prevent cardiovascular *** content of CoQ10 in the industrial Rhodobacter sphaeroides HY01 is hundreds of folds higher than normal physiological *** this study,we found that overexpression or optimization of the synthetic pathway failed CoQ10 overproduction in the HY01 ***,under phosphate-limited conditions(decreased phosphate or in the absence of inorganic phosphate addition),CoQ10 production increased significantly by 12%to220 mg/L,biomass decreased by 12%,and the CoQ10 productivity of unit cells increased by 27%.In subsequent fed-batch fermentation,CoQ10 production reached 272 mg/L in the shake-flask fermentation and 1.95 g/L in a 100-L bioreactor under phosphate ***,to understand the mechanism associated with CoQ10 overproduction under phosphate-limited conditions,the comparatve transcriptome analysis was *** results indicated that phosphate limitation combined with glucose fed-batch fermentation represented an effective strategy for CoQ10 production in the *** limitation induced a pleiotropic effect on cell metabolism,and that improved CoQ10 biosynthesis efficiency was possibly related to the disturbance of energy metabolism and redox potential.

关键词： R sphaeroides CoQ10 Phosphate limitation Overproduction Scale-up Transcriptome

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A Double-Crosslinked Self-Healing Antibacterial Hydrogel with Good Mechanical Performance for Wound Treatment

SSRN

引用

SSRN 2020年

作者： Wang, Lei Yang, Kun Li, Xiaozhen Zhang, Xuehui Zhang, Dawei Wang, Lu-Ning Lee, Chun-Sing Beijing Advanced Innovation Center for Materials Genome Engineering School of Materials Science and Engineering University of Science and Technology Beijing Beijing100083 China Department of Chemistry City University of Hong Kong 83 Tat Chee Avenue Kowloon Hong Kong Department of Dental Materials NMPA Key Laboratory Dental Materials & Dental Medical Devices Testing Center Peking University School and Hospital of Stomatology Zhongguancun South Avenue No 22 Beijing100081 China Corrosion and Protection Centre University of Science and Technology Beijing 30 Xueyuan Road Haidian District Beijing100083 China

Self-healing hydrogel systems usually suffer from poor mechanical performance stemmed from weaker and reversible non-covalent interactions or dynamic chemical bonds, which hamper their practical applications. This issue is addressed by adopting a double-crosslinking design via employing both dynamic Schiff base bonds and non-dynamic photo-induced crosslinking. This leads to the formation of a special topological structure which simultaneously provide good self-healing capability (healing efficiency of 73.5%) and good mechanical performance (good elastic recovery and tensile modulus of 157.4 kPa, close to modulus of native skin). The quaternary ammonium and protonated amino groups can provide superior antibacterial capability, while Schiff base formation between residual aldehyde groups and amino groups on tissue surface contribute to hydrogel’s good adhesion to tissues (5.9 kPa). Furthermore, the multifunctional hydrogel with desirable mechanical performance, self-healing capability, superior antibacterial capability and good tissue adhesion can significantly promote healing of infectious cutaneous wound, tissue remodeling and regeneration. © 2020, The Authors. All rights reserved.

关键词： Tissue regeneration

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