检索结果-内蒙古大学图书馆

Prediction of Potential Disease-Associated MicroRNAs Based on Hidden Conditional Random Field

Journal of Harbin Institute of Technology(New Series) 2018年第1期25卷 57-66页

作者： Maozu Guo Shuang Cheng Chunyu Wang Xiaoyan Liu Yang Liu School of Computer Science and Technology Harbin Institute of Technology Harbin 150001 China School of Electrical and Information Engineering Beijing University of Civil Engineering and Architecture Beijing 100044 China Beijing Key Laboratory for Research on Intelligent Processing Method of Building Big Data( Beijing University of Civil Engineering and Architecture) Beijing 100044China Institute of Materials China Academy of Engineering PhysicsMianyang 621700SichuanChina

MicroRNAs( miRNAs) are reported to be associated with various diseases. The identification of disease-related miRNAs would be beneficial to the disease diagnosis and prognosis. However,in contrast with the widely available expression profiling, the limited knowledge of molecular function restrict the development of previous methods based on network similarity measure. To construct reliable training data,the decision fusion method is used to prioritize the results of existing methods. After that,the performance of decision fusion method is validated. Furthermore,in consideration of the long range dependencies of successive expression values,Hidden Conditional Random Field model( HCRF) is selected and applied to miRNA expression profiling to infer disease-associated miRNAs. The results show that HCRF achieves superior performance and outperforms the previous methods. The results also demonstrate the power of using expression profiling for discovering disease-associated miRNAs.

关键词： expression profiling hidden conditional random field miRNA-disease association network

来源：评论

学校读者我要写书评

暂无评论

A java code protection scheme via dynamic recovering runtime instructions 18th

A java code protection scheme via dynamic recovering runtime...

引用

18th International Conference on Algorithms and Architectures for Parallel processing, ICA3PP 2018

作者： Jiajia, Sun Jinbao, Gao Yu-an, Tan Yu, Zhang Xiao, Yu School of Computer Science and Technology Beijing Institute of Technology Beijing100081 China School of Electrical and Information Engineering Beijing Key Laboratory of Intelligent Processing for Building Big Data Beijing University of Civil Engineering and Architecture Beijing100044 China China University of Mining and Technology Beijing100083 China Department of Computer Science and Technology Shandong University of Technology ZiboShandong255022 China

ISBN: (纸本)9783030050627

As Android operating system and applications on the device play important roles, the security requirements of Android applications increased as well. With the upgrade of Android system, Android runtime mode (ART mode) has gradually become the mainstream architecture of the Android operating system. ART introduces several improvements in Android, but it also introduces new ways to enhance malicious activities. This paper proposed a confidential finer granularity protection scheme for application programs under ART mode of ROOT Android devices. Taking Java method as the protection granularity, the protection scheme increased the accuracy of protecting targets. In addition, the protection scheme provided a more thorough protection for applications by combining dynamic loading technology and encryption technology in ART mode, and improved the security of Android applications. Experiments showed that the proposed protection scheme is effective. © Springer Nature Switzerland AG 2018.

关键词： Android (operating system)

来源：评论

学校读者我要写书评

暂无评论

DPHL:A DIA Pan-human Protein Mass Spectrometry Library for Robust Biomarker Discovery

引用

Genomics, Proteomics & Bioinformatics 2020年第2期18卷 104-119页

作者： Tiansheng Zhu Yi Zhu Yue Xuan Huanhuan Gao Xue Cai Sander R.Piersma Thang V.Pham Tim Schelfhorst Richard R.G.D.Haas Irene V.Bijnsdorp Rui Sun Liang Yue Guan Ruan Qiushi Zhang Mo Hu Yue Zhou Winan J.Van Houdt Tessa Y.S.Le Large Jacqueline Cloos Anna Wojtuszkiewicz Danijela Koppers-Lalic Franziska Bottger Chantal Scheepbouwer Ruud H.Brakenhoff Geert J.L.H.van Leenders Jan N.M.Ijzermans John W.M.Martens Renske D.M.Steenbergen Nicole C.Grieken Sathiyamoorthy Selvarajan Sangeeta Mantoo Sze S.Lee Serene J.Y.Yeow Syed M.F.Alkaff Nan Xiang Yaoting Sun Xiao Yi Shaozheng Dai Wei Liu Tian Lu Zhicheng Wu Xiao Liang Man Wang Yingkuan Shao Xi Zheng Kailun Xu Qin Yang Yifan Meng Cong Lu Jiang Zhu Jin'e Zheng Bo Wang Sai Lou Yibei Dai Chao Xu Chenhuan Yu Huazhong Ying Tony K.Lim Jianmin Wu Xiaofei Gao Zhongzhi Luan Xiaodong Teng Peng Wu Shi'ang Huang Zhihua Tao Narayanan G.Iyer Shuigeng Zhou Wenguang Shao Henry Lam Ding Ma Jiafu Ji Oi L.Kon Shu Zheng Ruedi Aebersold Connie R.Jimenez Tiannan Guo Zhejiang Provincial Laboratory of Life Sciences and Biomedicine Westlake UniversityHangzhou 310024China Key Laboratory of Structural Biology of Zhejiang Province School of Life SciencesWestlake UniversityHangzhou 310024China Institute of Basic Medical Sciences Westlake Institute for Advanced StudyHangzhou 310024China School of Computer Science Shanghai Key Laboratory of Intelligent Information ProcessingFudan UniversityShanghai 200433China Thermo Fisher Scientific(BREMEN)GmbH Bremen 28195Germany OncoProteomics Laboratory Department of Medical OncologyVU University Medical CenterVU UniversityAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamUrologyCancer Center AmsterdamAmsterdam 1011The Netherlands Thermo Fisher Scientific Shanghai 201206China The Netherlands Cancer Institute Surgical OncologyAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamSurgeryCancer Center AmsterdamAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamPediatric Oncology/HematologyCancer Center AmsterdamAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamHematologyCancer Center AmsterdamAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamMedical OncologyCancer Center AmsterdamAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamNeurosurgeryCancer Center AmsterdamAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamPathologyCancer Center AmsterdamAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamOtolaryngology/Head and Neck SurgeryCancer Center AmsterdamAmsterdam 1011The Netherlands Erasmus MC University Medical Center PathologyRotterdam 1016LVThe Netherlands Erasmus MC University Medical Center SurgeryRotterdam 1016LVThe Netherlands Erasmus MC University Medical Center Medical OncologyRotterdam 1016LVThe Netherlands Department of Anatomical Pathology Singapore General HospitalSingapore 169608Singapore Division of Medical Scie

To address the increasing need for detecting and validating protein biomarkers in clinical specimens,mass spectrometry(MS)-based targeted proteomic techniques,including the selected reaction monitoring(SRM),parallel reaction monitoring(PRM),and massively parallel dataindependent acquisition(DIA),have been *** optimal performance,they require the fragment ion spectra of targeted peptides as prior *** this report,we describe a MS pipeline and spectral resource to support targeted proteomics studies for human tissue *** build the spectral resource,we integrated common open-source MS computational tools to assemble a freely accessible computational workflow based on *** then applied the workflow to generate DPHL,a comprehensive DIA pan-human library,from 1096 data-dependent acquisition(DDA)MS raw files for 16 types of cancer *** extensive spectral resource was then applied to a proteomic study of 17 prostate cancer(PCa)***,PRM validation was applied to a larger study of 57 PCa patients and the differential expression of three proteins in prostate tumor was *** a second application,the DPHL spectral resource was applied to a study consisting of plasma samples from 19 diffuse large B cell lymphoma(DLBCL)patients and 18 healthy control *** expressed proteins between DLBCL patients and healthy control subjects were detected by DIA-MS and confirmed by *** data demonstrate that the DPHL supports DIA and PRM MS pipelines for robust protein biomarker *** is freely accessible at https://***/page/***?id=IPX0001400000.

关键词： data-independent acquisition Parallel reaction monitoring Spectral library Prostate cancer Diffuse large B cell lymphoma

来源：评论

学校读者我要写书评

暂无评论

Crowd-Guided Entity Matching with Consolidated Textual data

引用

Journal of Computer Science & Technology 2017年第5期32卷 858-876页

作者： Zhi-Xu Li Qiang Yang An Liu Guan-Feng Liu Jia Zhu Jia-Jie Xu Kai Zheng Min Zhang School of Computer Science and Technology Soochow University Suzhou 215006 China Guangdong Key Laboratory of Big Data Analysis and Processing Guangzhou 510006 China School of Computer Science and Technology Soochow University Suzhou 215006 China School of Computer South China Normal University Guangzhou 510631 China School of Computer Science and Technology Soochow University Suzhou 215006 China Beijing Key Laboratory of Big Data Management and Analysis Methods Beijing 100872 China

Entity matching (EM) identifies records referring to the same entity within or across databases. Existing methods using structured attribute values (such as digital, date or short string values) may fail when the structured information is not enough to reflect the matching relationships between records. Nowadays more and more databases may have some unstructured textual attribute containing extra consolidated textual information (CText) of the record, but seldom work has been done on using the CText for EM. Conventional string similarity metrics such as edit distance or bag-of-words are unsuitable for measuring the similarities between CText since there are hundreds or thousands of words with each piece of CText, while existing topic models either cannot work well since there are no obvious gaps between topics in CText. In this paper, we propose a novel cooccurrence-based topic model to identify various sub-topics from each piece of CText, and then measure the similarity between CText on the multiple sub-topic dimensions. To avoid ignoring some hidden important sub-topics, we let the crowd help us decide weights of different sub-topics in doing EM. Our empirical study on two real-world datasets based on Amzon Mechanical Turk Crowdsourcing Platform shows that our method outperforms the state-of-the-art EM methods and Text Understanding models.

关键词： entity matching consolidated textual data crowdsourcing

来源：评论

学校读者我要写书评

暂无评论

Cascade control for supply air temperature in a variable air volume system

引用

IOP Conference Series. Earth and Environmental Science 2019年第1期238卷 012021-012021页

作者： Zhuang, Junhua Chen, Yimin Wu, Jie School of Electrical and Information Engineering Beijing University of Civil Engineering and Architecture Beijing China Beijing Key Laboratory of Intelligent Processing for Building Big Data Beijing China School of Electrical and Information Engineering Beijing University of Civil Engineering and Architecture Beijing China Beijing Key Laboratory of Intelligent Processing for Building Big Data Beijing China Department of Civil Architectural and Environmental Engineering Drexel University Philadelphia PA 19104 USA Beijing ZXT M&E Engineering Consultant Co. Ltd

Most supply air temperature in variable air volume systems is typically set at 55F(13 °C) that is design value in these systems. However, sometimes the load of cooling varies greatly in different zones, and it means the indoor temperature of low-load zones is lower than comfortable value, even if the supply air damper is at the minimum value that is not closed for minimum outside air requirement. Meanwhile, in transition season, the indoor temperature is also lower due to low outdoor temperature. These factors provided an opportunity to apply higher supply air temperature to reduce air handling unit (AHU) cooling load and box reheating. In this paper, a cascade control method is used to raise the supply air temperature. The external control loop controls the setting value of supply air temperature with the minimum supply air volume as the control target. And the internal control loop controls the supply air temperature by regulating valve. The cascade structure can solve the problem that the time constant of the system is too large. The simulation results show that the quality of control is good and the reheating can be cancelled.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Deep Multi-Metric Learning for Person Re-Identification

Deep Multi-Metric Learning for Person Re-Identification

引用

IEEE International Conference on Multimedia and Expo (ICME)

作者： Yongxin Ge Xinqian Gu Min Chen Hongxing Wang Dan Yang Key Laboratory of Dependable Service Computing in Cyber Physical Society Ministry of Education (Chongqing University) Chongqing China Key Laboratory of Intelligent Information Processing of Chinese Academy of Sciences (CAS) Institute of Computing Technology CAS Beijing China School of Big Data & Software Engineering Chongqing University Chongqing China

In this paper, to exploit more discriminative information of the global-body and body-parts features, we present a novel deep multi-metric learning (DMML) network for person re-identification under the triplet framework. The main novelty of our learning framework lies in two aspects: 1) Unlike most existing metric learning-based approaches, which learn only one distance metric for comparison, our DMM-L method aims to learn different metrics for the global-body and body-parts features respectively by using convolutional neural network (CNN); 2) A new multi-metric loss function is proposed to train the DMML network, under which the distance of each negative pair is greater than that of each positive pair by a predefined margin, and the correlations of different metrics are maximized. Compared with the previous person re-identification methods that have shown state-of-the-art performances, our DMML approach can achieve competitive results on the challenging CUHK03, CUHKOl, VIPeR and iLIDS datasets.

关键词： Measurement Image color analysis Feature extraction Training Machine learning Kernel Learning systems

来源：评论

学校读者我要写书评

暂无评论

Multi-temporal MOD09A1-based detecting of major growth stages of paddy rice on a provincial scale 37

Multi-temporal MOD09A1-based detecting of major growth stage...

引用

37th Annual IEEE International Geoscience and Remote Sensing Symposium, IGARSS 2017

作者： Huang, Linsheng Zhang, Shasha Zhao, Jinling Huang, Wenjiang Huang, Jinyang Qi, Xiaobo Anhui Engineering Laboratory Agro-Ecological Big Data Anhui University Hefei230601 China Key Laboratory of Intelligent Computing and Signal Processing Ministry of Education Anhui University Hefei230039 China Key Laboratory of Digital Earth Science Institute of Remote Sensing and Digital Earth Chinese Academy of Sciences Beijing100094 China

ISBN: (纸本)9781509049516

Growth stage information is a very primary parameter for managing the grain crop. In this study, time series Enhanced Vegetation Index (EVI) data in 2015 were obtained in Anhui Province, China based on 8-day composite MOD09A1 data products, and the extraction method of rice phenology was specifically analyzed at a provincial scale. HANTS (Harmonic Analysis of Time Series) filtering algorithm was firstly used to smooth the time series EVI curves and identify every growth and development period of paddy rice. The results indicate that HANTS has a better performance in removing noise, restoring original information and retain the change information of multi-temporal EVI curves. The primary planting regions were located in the southern Huai-River areas, from early June to late June in 2015. It turned into the transplanting stage in succession from south to north and followed by the heading stage in succession in early August. From early September to late October, it turned into mature stage from south to north in succession. © 2017 IEEE.

关键词： Indexes

来源：评论

学校读者我要写书评

暂无评论

Linked data Crowdsourcing Quality Assessment based on Domain Professionalism

引用

Journal of Physics: Conference Series 2019年第5期1187卷

作者： Lu Yang Li Huang Zhenzhen Liu School of Computer Science and Technology Wuhan University of Science and Technology Wuhan 430065 China Key Laboratory of Intelligent Information Processing and Real-time Industrial System in Hubei Province Wuhan 430065 China Institute of Big Data Science and Engineering Wuhan University of Science and Technology Wuhan 430065 China Key Laboratory of Rich-media Knowledge Organization and Service of Digital Publishing Content National Press and Publication Administration Beijing 100038 China

With the rapid development of Internet technology, crowdsourcing, as a flexible, effective and low-cost problem-solving method, has begun to receive more and more attention. The use of crowdsourcing to evaluate the quality of linked data has also become a research hotspot. This paper proposes the concept of Domain Specialization Test (DST), which uses domain professional testing tasks DSTs to evaluate the professionalism of workers, and combines the idea of Mini-batch Gradient Descent (MBGD) to improve the EM algorithm, and the MBEM algorithm is proposed to achieve efficient and accurate evaluation of task results. The experimental results show that the proposed method can screen out the appropriate workers for the linked data crowdsourcing task and improve the accuracy and iteration efficiency of the results.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Emergency Event Matching using Hierarchical Blocking Method

引用

Journal of Physics: Conference Series 2019年第5期1187卷

作者： Chang Wen Yu Liu College of Computer Science and Technology Wuhan University of Science and Technology Wuhan 430065 China Key Laboratory of Intelligent Information Processing and Real-time Industrial System in Hubei Province Wuhan 430065 China Institute of Big Data Science and Engineering Wuhan University of Science and Technology Wuhan 430065 China Key Laboratory of Rich-media Knowledge Organization and Service of Digital Publishing Content National Press and Publication Administration Beijing 100038 China

With the extensive application of the knowledge base (KB), how to complete it is a hot topic on Semantic Web. However, many problems go with the big data, and the event matching is one of these problems, which is finding out the entities referring to the same things in the real world and also the key point in the extending process. To enrich the emergency knowledge base (E-SKB) we constructed before, we need to filter out the news from several web pages and find the same news to avoid data redundancy. In this paper, we proposed a hierarchy blocking method to reduce the times of comparisons and narrow down the scope by extracting the news properties as the blocking keys. The method transforms the event matching problem into a clustering problem. Experimental results show that the proposed method is superior to the existing text clustering algorithm with high precision and less comparison times.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Tri-level combination for image representation 17th

Tri-level combination for image representation

引用

17th Pacific-Rim Conference on Multimedia, PCM 2016

作者： Li, Ruiying Zhang, Chunjie Huang, Qingming School of Computer and Control Engineering University of Chinese Academy of Sciences Beijing China Key Laboratory of Big Data Mining and Knowledge Management Chinese Academy of Sciences Beijing China Key Laboratory of Intelligent Information Processing Institute of Computing Technology Chinese Academy of Sciences Beijing China

ISBN: (纸本)9783319488899

The context of objects can provide auxiliary discrimination beyond objects. However, this effective information has not been fully explored. In this paper, we propose Tri-level Combination for Image Representation (TriCoIR) to solve the problem at three different levels: object intrinsic, strongly-related context and weakly-related context. Object intrinsic excludes external disturbances and more focuses on the objects themselves. Strongly-related context is cropped from the input image with a more loose bound to contain surrounding context. Weaklyrelated one is recovered from the image other than object for global context. First, strongly and weakly-related context are constructed from input images. Second, we make cascade transformations for more intrinsical object information, which depends on the consistency between generated global context and input images in the regions other than object. Finally, a joint representation is acquired based on these three level features. The experiments on two benchmark datasets prove the effectiveness of TriCoIR. © Springer International Publishing AG 2016.

关键词： Image representation

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：