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Mapping the Behavioral Signatures of Shank3b Mice in Both Sexes

Neuroscience Bulletin 2024年第9期40卷 1299-1314页

作者： Jingjing Liu Jialin Ye Chunyuan Ji Wenting Ren Youwei He Fuqiang Xu Feng Wang NMPA Key Laboratory for Research and Evaluation of Viral Vector Technology in Cell and Gene Therapy Medicinal Products Shenzhen-Hong Kong Institute of Brain ScienceShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen518055China Shenzhen Key Laboratory of Viral Vectors for Biomedicine Translational Research Center for the Nervous SystemShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen518055China Key Laboratory of Quality Control Technology for Virus-Based Therapeutics Guangdong Provincial Medical Products AdministrationShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen518055China Shenzhen Key Lab of Translational Research for Brain Diseases Translational Research Center for the Nervous SystemShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen518055China Guangdong Provincial Key Laboratory of Brain Connectome and Behavior the Brain Cognition and Brain Disease InstituteShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen518055China CAS Key Laboratory of Brain Connectome and Manipulation the Brain Cognition and Brain Disease InstituteShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen518055China University of Chinese Academy of Sciences Beijing100049China

Autism spectrum disorders(ASD)are characterized by social and repetitive *** the ASD mouse model with Shank3b mutations is widely used in ASD research,the behavioral phenotype of this model has not been fully ***,a 3D-motion capture system and linear discriminant analysis were used to comprehensively record and analyze the behavioral patterns of male and female Shank3b mutant *** was found that both sexes replicated the core and accompanied symptoms of ASD,with significant sex ***,Shank3b heterozygous knockout mice exhibited distinct autistic behaviors,that were significantly different from those those observed in the wild type and homozygous knockout *** findings provide evidence for the inclusion of both sexes and experimental approaches to efficiently characterize heterozygous transgenic models,which are more clinically relevant in autistic studies.

关键词： Autism Shank3b Spontaneous behavior 3D animal motion-capture system Computational ethology Sex differences

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Fast N–x Topology Analysis Method Based on Node Branch Calculation Model

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Dianwang Jishu/Power system technology 2023年 47卷 51-59页

作者： Liu, Sheng Shi, Shangqiu Sun, Bo Yu, Yijun Tang, Junci Li, Tong Beijing Key Laboratory of Research and System Evaluation of Power Dispatching Automation Technology China Electric Power Research Institute Haidian District Beijing100192 China State Grid Liaoning Electric Power Corporation Liaoning Province Shenyang110000 China State Grid Liaoning Electric Power Research Institute Liaoning Province Shenyang110000 China

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A SINS Error Correction Approach Based on Dual-Threshold ZV Detection and Cubature Kalman Filter

A SINS Error Correction Approach Based on Dual-Threshold ZV ...

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2023 IEEE International Conference on systems, Man, and Cybernetics, SMC 2023

作者： Xu, Ruijie Chen, Shichao Sun, Wenqiao Lv, Yisheng Luo, Jialiang Tang, Ying Institute of Automation Chinese Academy of Sciences College of Information Science & Technology Beijing University of Chemical Technology The State Key Laboratory for Management and Control of Complex System State Key Laboratory of Multimodal Artificial Intelligence Systems Beijing China Institute of Automation Chinese Academy of Sciences The Center of National Railway Intelligent Transportation System Engineering and Technology China Academy of Railway Sciences Corporation Limited The State Key Laboratory for Management and Control of Complex System State Key Laboratory of Multimodal Artificial Intelligence Systems Beijing China Transportation and Economics Research Institute The Center of National Railway Intelligent Transportation System Engineering and Technology China Academy of Railway Sciences Corporation Limited Beijing China Institute of Automation Chinese Academy of Sciences The State Key Laboratory for Management and Control of Complex System State Key Laboratory of Multimodal Artificial Intelligence Systems Beijing China Institute of Automation Chinese Academy of Sciences China University of Geosciences Beijing School of Information Engineering The State Key Laboratory for Management and Control of Complex System State Key Laboratory of Multimodal Artificial Intelligence Systems Beijing China Rowan University Department of Electrical and Computer Engineering Glassboro United States

ISBN: (纸本)9798350337020

Global Navigation Satellite systems (GNSS) can provide real-time positioning information for outdoor users, but cannot for indoor scenarios or heavily occluded outdoor scenarios. Strap-down Inertial Navigation system (SINS) are widely used to locate people in complex interior or heavily occluded outdoor scenarios due to its light weight and low power consumption. However, IMU of SINS are noisy, and the sampling data error is large, which is a divergence of the error with time. Therefore, it will generate a positioning accumulation error, which affects the final positioning accuracy. The problem of cumulative IMU errors is usually dealt with by Zero-Velocity Update (ZUPT). The zero-velocity detection part of basic ZUPT method usually uses a single threshold to determine the gait of pedestrian, which often has the problem of gait misjudgment and omission. To address these problems, this paper proposes a composite conditional detection method to solve the problem of misjudgment in the zero-velocity interval. In addition, we redesign the zero-velocity update algorithm and uses the Cubature Kalman filter (CKF) for pedestrian positioning error correction. The experimental results demonstrate that the proposed ZUPT method based on dual-threshold detection can better detect the interval between pedestrian motion and stationery than ones with single threshold. The zero-velocity update algorithm based on CKF has higher performance than conventional EKF and UKF methods, which constrains the cumulative error of SINS to about 0.2% of the whole walking distance. © 2023 IEEE.

关键词： Cubature Kalman Filter Inertial Pedestrian Navigation Zero-Velocity Update

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research on the security sharing method of power grid dispatching control data based on Alliance Blockchain and Zero-Knowledge Proof technology

Research on the security sharing method of power grid dispat...

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IEEE Advanced Information Management,Communicates,Electronic and automation Control Conference (IMCEC)

作者： Zhoujie Zhang Lei Tao Can Cui Yunhao Huang Qingbo Yang Qiong Feng Xinxin Ma Yupeng Huang Beijing Key Lab of Research and System Evaluation of Power Dispatching Automation Technology China Electric Power Research Institute Beijing China

ISBN: (纸本)9781665479691

With the widespread application of power system digital technology and the advancement of dispatch control cloud construction, the development of power grid regulation business presents the basic characteristics of many business participants, frequent business interactions, and large data exchange. The alliance chain technology in blockchain technology has become an important basis for the research of this paper because of its native support for multi-party business scenarios. Based on the alliance blockchain technology, this paper designs a multi-channel data isolation scheme for the grid dispatching control business to achieve efficient data sharing within a controllable range. At the same time, in order to ensure the security of the private data in the grid dispatching control business in the business interaction process. Furthermore, this paper designs a business interaction process for private data based on the zero-knowledge verification algorithm. Combined with smart contract technology, it automatically completes the entire network verification process of data encryption and zero-knowledge credentials, and realizes data security interaction in secret scenarios.

关键词： Data security Smart contracts Process control Ontologies dispatching Power grids Regulation

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The Realization and Application of Dispatch Training Simulator based on Multi-machine technology 5

The Realization and Application of Dispatch Training Simulat...

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5th IEEE Advanced Information technology, Electronic and automation Control Conference, IAEAC 2021

作者： Wang, Gang Wang, Baihuai Huang, Zhigang Fang, Xuezhen Xu, Xuan Sun, Zhengming Han, Yi State Grid Tianjin Electric Power Co. Ltd Tianjin China China Electric Power Research Institute Beijing Key Laboratory of Research and System Evaluation of Power Dispatching Automation Technology Beijing China

ISBN: (纸本)9781728180281

Traditional dispatcher training simulator (DTS) is commonly used for individual practice or joint anti-accident exercises that all people in single scenario. Problems includes the lack of sharing mechanism, fixed process and single machine control, which cannot support multiple people to train or do competitive exam in the same scenario simultaneously. In order to expand the use scenarios of DTS and solve the above problems, this paper suggests that applying the multi-machine technology to traditional DTS, including cloud storage technology through WEB to realize the sharing of exam cases, and establish an event-aware triggering mechanism and multi-machine centralized control technology of simulation virtual machines to achieve the individual process leading and multi-people competitive exam centralized control and interaction. Finally, by an simulation application instance of DTS in the multi-people competition and comparing with the traditional DTS functions and performance, the feasibility and practicability of DTS system in multi-person competitive exam scenario after implementing these new technologies are verified. © 2021 IEEE.

关键词： Process control

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Performance Realization for Gas Turbine system: Adaptive Constraint Regulation Framework 6

Performance Realization for Gas Turbine System: Adaptive Con...

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6th International Conference on Electronic Engineering and Informatics, EEI 2024

作者： Du, Peihao Zhong, Weimin Li, Hongyi Li, Linlin Peng, Xin He, Kaixun School of Electronic and Information Engineering Chongqing Key Laboratory of Generic Technology and System of Service Robots Southwest University Chongqing400715 China School of Automation and Electrical Engineering University of Science and Technology Beijing Key Laboratory of Knowledge Automation for Industrial Processes of Ministry of Education Beijing100083 China East China University of Science and Technology Key Laboratory of Smart Manufacturing in Energy Chemical Process Ministry of Education Shanghai200237 China Engineering Research Center of Process System Engineering Ministry of Education East China University of Science and Technology Shanghai200237 China College of Electrical Engineering and Automation Shandong University of Science and Technology Qingdao266590 China

ISBN: (纸本)9798350353594

With the excessive consumption of fossil energy and the growing environmental pollution caused by its combustion, the gas turbine system (GTS) plays a key role in distributed renewable energy fields due to its versatility, efficiency and controllability. This paper focuses on the adaptive constraint regulation problem for the GTS with time-varying load disturbance, thereby facilitating exact speed tracking to regulate the fuel flow for the turbine under variable load conditions. Therein, a residual transformation dynamics based on the performance function are established for triggering the preset-time residual convergence and output performance constraints. Then, an adaptive constraint controller is developed to ensure the desired regulation level of the GTS. Simulation results illustrate that the proposed strategy can mitigate the load disturbance effect and guarantee the GTS performance constraints. © 2024 IEEE.

关键词： Gas turbines

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Optimal scheduling strategies for electrochemical energy storage power stations in the electricity spot market

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Frontiers in Energy research 2024年 12卷

作者： Li, Yuanyuan Zhang, Shuyan Yang, Luye Gong, Qihang Li, Xiaojing Fan, Biwu Beijing Key Laboratory of Research and System Evaluation of Power China Electric Power Research Institute Power Automation Department Beijing China PKU-Changsha Institute for Computing and Digital Economy Changsha China

Introduction: This paper constructs a revenue model for an independent electrochemical energy storage (EES) power station with the aim of analyzing its full life-cycle economic benefits under the electricity spot market. Methods: The model integrates the marginal degradation cost (MDC), energy arbitrage, ancillary services, and annual operation and maintenance (O&M) costs to calculate the net profits of the EES power station. Using an iterative optimization approach, we determine the optimal MDC and analyze the economic end of life (EOL) for different types of EES power stations. Results: By examining real-world examples from the California energy market, we find that the full life-cycle benefits of an EES power station peak when its MDC is optimal, at $45/MWh-throughput. Under these conditions, the economic and physical EOL of commercial/industrial EES power station is 9 years, while the economic EOL of residential-grade EES power station is 8 years, which is shorter than their physical EOL of 9 years. Discussion: The study further indicates that the economic life of an EES power station is influenced by multiple factors, and operators need to determine the optimal economic EOL to maximize revenue based on battery degradation characteristics, market conditions and operational strategy. Copyright © 2024 Li, Zhang, Yang, Gong, Li and Fan.

关键词： Profitability

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Impact of net-zero emissions on atmospheric CO_(2) concentration in China: Ideal simulations based on the GEOS-Chem model

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Science China Earth Sciences 2025年第3期68卷 867-881页

作者： Jingye TAN Jun WANG Huiqin MAO Hengmao WANG Zhiqiang LIU Meirong WANG Ran YAN Xunmei WANG Fei JIANG Frontiers Science Center for Critical Earth Material Cycling International Institute for Earth System ScienceNanjing UniversityNanjing 210023China Jiangsu Provincial Key Laboratory of Geographic Information Science and Technology Key Laboratory for Land Satellite Remote Sensing Applications of Ministry of Natural ResourcesSchool of Geography and Ocean ScienceNanjing UniversityNanjing 210023China Satellite Environmental Application Center Ministry of Environmental ProtectionBeijing 100094China CMA Key Open Laboratory of Transforming Climate Resources to Economy Chongqing Institute of Meteorological SciencesChongqing 401147China State Key Laboratory of Climate System Prediction and Risk Management Key Laboratory of Meteorological DisasterMinistry of EducationCollaborative Innovation Center on Forecast and Evaluation of Meteorological DisastersNanjing University of Information Science and TechnologyNanjing 210044China Xizang Field Station for Scientific Observation and Research on Atmospheric Water Cycle in Mêdog Xigazêand Mêdog National Climate ObservatoryXizang Meteorological ServiceLhasa 850000China

Elevated atmospheric carbon dioxide(CO_(2)) concentrations have caused global climate change such as global warming and more frequent climate extremes. Countries worldwide have proposed carbon neutrality strategies to curb the rising CO_(2) concentrations. To investigate the impact of China's carbon neutrality goal on atmospheric CO_(2) concentrations, we conducted a series of ideal simulations from 2015 to 2019 using a global 3D chemistry transport model, Goddard Earth Observing system Chemistry(GEOS-Chem). Compared with the column-averaged dry-air mole fraction of atmospheric CO_(2) (XCO_(2) ) from Orbiting Carbon Observatory-2(OCO-2) and surface CO_(2) measurements in Obs Pack, we find that GEOS-Chem effectively reproduces the spatiotemporal variability of CO_(2) . The model exhibits a root mean square error(RMSE) of 1.51 ppm(R^(2)=0.89) for OCO-2 XCO_(2) in China and 2.65 ppm(R^(2)=0.75) for surface CO_(2) concentrations at the WLG station. Further, compared to 2.83 ppm yr^(-1)in the control experiment, we suggest that net-zero CO_(2) emissions in China decelerate the increasing trends of XCO_(2) to 1.81 ppm yr^(-1),making a decrease of approximately 35.89%. Meanwhile, the seasonal cycle amplitude(SCA) of XCO_(2) is moderately reduced from 7.39±0.81 to 6.75±0.70 ppm, representing a relative reduction of 9.91%. Spatially, net-zero CO_(2) emissions induce a more significant decrease in XCO_(2) trends over northern and southern China, while their impact on SCA is more evident in northern and northeastern China. Moreover, ideal experiments demonstrate that zero fossil CO_(2) emissions lead to a greater attenuation of the linear trends of XCO_(2) by 40.81%, while the absence of terrestrial CO_(2) sinks largely diminishes the SCA by 16.61%. Additionally,trends and SCA in surface CO_(2) concentrations exhibit almost identical decreasing responses to net-zero CO_(2) emissions but display greater sensitivities compared to XCO_(2) . Overall, our study underscores the pote

关键词： XCO_(2) GEOS-Chem Carbon neutrality Net-zero emissions Surface CO_(2)concentrations

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research on Consistency Tracing technology of dispatching Control Model Data based on Blockchain 5

Research on Consistency Tracing Technology of Dispatching Co...

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5th IEEE Advanced Information technology, Electronic and automation Control Conference, IAEAC 2021

作者： Zhang, Zhoujie Cui, Can Tao, Lei Wang, Jiaqi Li, Dapeng Wu, Shuzhou Feng, Qiong Yang, Qingbo Chen, Jian Zhang, Jie Zhang, Peng Zhang, Zhijun China Electric Power Research Institute Beijing Key Lab of Research and System Evaluation of Power Dispatching Automation Technology Beijing China State Grid Tianjin Electric Power Company Tianjin China

In the era of big data and artificial intelligence development, data has become an important asset. Open data ecology has become an inevitable choice to promote business success. In the process of data open sharing, data provenance technology can supervise the data sharing path among multiple entities, and protect the interests of data owners. This paper proposes a data provenance technology for dispatching and control data based on blockchain. Firstly, a data provenance model is designed based on blockchain, which describes the provenance process of dispatching and control model ***, the distributed ledger of blockchain is used to record the data sharing path described by the data traceability ***, the automatic implementation of provenance process is realized by using smart contract of blockchain. © 2021 IEEE.

关键词： Smart contract

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Short Circuit Fault Characteristics of Low Frequency AC Transmission system Based on Modular Multilevel Matrix Converter

Short Circuit Fault Characteristics of Low Frequency AC Tran...

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2023 International Conference on Power Energy systems and Applications, ICoPESA 2023

作者： Zhao, Zexin Han, Bin Zhao, Guoliang Xu, Yunfei Lu, Zhengang Xiang, Nianwen Wang, Shulai China Electric Power Research Institute Power System Department Beijing China State Grid Smart Grid Research Institute State Key Laboratory of Advanced Power Transmission Technology Beijing China Hefei University of Technology School of Electrical Engineering and Automation Hefei China

ISBN: (纸本)9798350345605

Compared with power frequency AC transmission and DC transmission, low frequency AC transmission has its unique advantages, which is suitable for long distance transmission, large scale renewable generation and regulation of regional power grid. The fault characteristics affect the system design and operation, which is necessary to study. From the perspective of system topology and converter control, the characteristics of three-phase short circuit fault are analyzed and a simulation model is built on PSCAD for verification in this paper. After a fault occurs, it can be divided into two stages before and after the control responses. Before the control responses, the overvoltage is generated between the terminals of branch reactors and modular capacitors discharges. After the control responses, system characteristics are related to fault location and control strategy. The control and modulation of the converter can make the low frequency and power frequency systems interact with each other. This study can provide a reference for the parameters of equipment and converter control, as well as fault protection in low frequency systems. © 2023 IEEE.

关键词： Timing circuits

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