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Joint high-resolution feature learning and vessel-shape aware convolutions for efficient vessel segmentation

computers in Biology and Medicine 2025年 191卷 109982-109982页

作者： Zhang, Xiang Zhu, Qiang Hu, Tao Guo, Song Bian, Genqing Dong, Wei Hong, Rao Lin, Xia Ling Wu, Peng Zhou, Meili Yan, Qingsen Mohi-ud-din, Ghulam Ai, Chen Li, Zhou College of Information and Control Engineering Xi'an University of Architecture and Technology Xi'an China Shaanxi Provincial Key Lab of Bigdata of Energy and Intelligence Processing School of Physics and Electronic Information Yanan University Yanan China School of Computer Science and Engineering Northwestern Polytechnical University Xi'an China School of Software Nanchang University Nanchang China School of Cyber Security Zhejiang University Hangzhou China Department of Basic Education and Research Jiangxi Police College Nanchang China Northwestern Polytechnical University China

Clear imagery of retinal vessels is one of the critical shreds of evidence in specific disease diagnosis and evaluation, including sophisticated hierarchical topology and plentiful-and-intensive capillaries. In this work, we propose a new topology- and shape-aware model named Multi-branch Vessel-shaped Convolution Network (MVCN) to adaptively learn high-resolution representations from retinal vessel imagery and thereby capture high-quality topology and shape information thereon. Two steps are involved in our pipeline. The former step is proposed as Multiple High-resolution Ensemble Module (MHEM) to enhance high-resolution characteristics of retinal vessel imagery via fusing scale-invariant hierarchical topology thereof. The latter is a novel vessel-shaped convolution that captures the retinal vessel topology to emerge from unrelated fundus structures. Moreover, our MVCN of separating such topology from the fundus is a dynamical multiple sub-label generation via using epistemic uncertainty, instead of manually separating raw labels to distinguish definitive and uncertain vessels. Compared to other existing methods, our method achieves the most advanced AUC values of 98.31%, 98.80%, 98.83%, and 98.65%, and the most advanced ACC of 95.83%, 96.82%, 97.09%,and 96.66% in DRIVE, CHASE_DB1, STARE, and HRF datasets. We also employ correctness, completeness, and quality metrics to evaluate skeletal similarity. Our method's evaluation metrics have doubled compared to previous methods, thereby demonstrating the effectiveness thereof. © 2025 Elsevier Ltd

关键词： Ophthalmology

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Visual Tuning

arXiv

引用

arXiv 2023年

作者： Yu, Bruce X.B. Chang, Jianlong Wang, Haixin Liu, Lingbo Wang, Shijie Wang, Zhiyu Lin, Junfan Xie, Lingxi Li, Haojie Lin, Zhouchen Tian, Qi Chen, Chang Wen Zhejiang University University of Illinois Urbana-Champaign Institute Zhejiang University China Huawei China National Engineering Research Center for Software Engineering Peking University China Peng Cheng Laboratory China College of Computer Science and Engineering Shandong University of Science and Technology China National Key Lab of General AI School of Intelligence Science and Technology Peking University China Department of Computing The Hong Kong Polytechnic University Hong Kong

Fine-tuning visual models has been widely shown promising performance on many downstream visual tasks. With the surprising development of pre-trained visual foundation models, visual tuning jumped out of the standard modus operandi that fine-tunes the whole pre-trained model or just the fully connected layer. Instead, recent advances can achieve superior performance than full-tuning the whole pre-trained parameters by updating far fewer parameters, enabling edge devices and downstream applications to reuse the increasingly large foundation models deployed on the cloud. With the aim of helping researchers get the full picture and future directions of visual tuning, this survey characterizes a large and thoughtful selection of recent works, providing a systematic and comprehensive overview of existing work and models. Specifically, it provides a detailed background of visual tuning and categorizes recent visual tuning techniques into five groups: fine-tuning, prompt tuning, adapter tuning, parameter tuning, and remapping tuning. Meanwhile, it offers some exciting research directions for prospective pre-training and various interactions in visual tuning. Copyright © 2023, The Authors. All rights reserved.

关键词： Vision

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Vaccine Allocation Strategy for Addressing Vaccine-Induced Asymptomatic Infections

Vaccine Allocation Strategy for Addressing Vaccine-Induced A...

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IEEE WIC ACM International Conference on Web intelligence (WI)

作者： Aibin Tang Yineng Gao Miao Liu Yue Peng Jiming Liu Benyun Shi College of Computer and Information Engineering Nanjing Tech University Nanjing P.R. China College of Artificial Intelligence Nanjing Tech University Nanjing P.R. China Department of Computer Science Hong Kong Baptist University Hong Kong State Key Lab for Novel Software Technology Nanjing University P.R. China

This study investigates the role of mass vaccination in mitigating the impact of infectious diseases, with a focus on the often-overlooked issue of asymptomatic carriers among vaccinated individuals. To accurately capture the occurrence of asymptomatic infections after vaccination, we propose a SEIAQ model that incorporates age-specific contact patterns in a population. Using census data from Shanghai, China, we simulate the potential transmission of the disease in an age-specific structured population. In light of potential constraints on vaccine coverage during the early stages of an epidemic, we also propose a vaccine allocation strategy that prioritizes different age groups based on the next-generation matrix concept. Our simulation results demonstrate that this strategy significantly reduces overall infections and the proportion of symptomatic infections. These findings highlight the effectiveness of the proposed strategy in containing disease spread, particularly when the vaccine may not fully prevent asymptomatic infections.

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Online Container Scheduling for Low-Latency IoT Services in Edge Cluster Upgrade: A Reinforcement Learning Approach

arXiv

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arXiv 2023年

作者： Cui, Hanshuai Tang, Zhiqing Lou, Jiong Jia, Weijia Institute of Artificial Intelligence and Future Networks Beijing Normal University Zhuhai519087 China School of Artificial Intelligence Beijing Normal University Beijing100875 China Department of Computer Science and Engineering Shanghai Jiao Tong University Shanghai200240 China Guangdong Key Lab of AI and Multi-Modal Data Processing BNU-HKBU United International College Zhuhai519087 China

In Mobile Edge Computing (MEC), Internet of Things (IoT) devices offload computationally-intensive tasks to edge nodes, where they are executed within containers, reducing the reliance on centralized cloud infrastructure. Frequent upgrades are essential to maintain the efficient and secure operation of edge clusters. However, traditional cloud cluster upgrade strategies are ill-suited for edge clusters due to their geographically distributed nature and resource limitations. Therefore, it is crucial to properly schedule containers and upgrade edge clusters to minimize the impact on running tasks. In this paper, we propose a low-latency container scheduling algorithm for edge cluster upgrades. Specifically: 1) We formulate the online container scheduling problem for edge cluster upgrade to minimize the total task latency. 2) We propose a policy gradient-based reinforcement learning algorithm to address this problem, considering the unique characteristics of MEC. 3) Experimental results demonstrate that our algorithm reduces total task latency by approximately 27% compared to baseline algorithms. Copyright © 2023, The Authors. All rights reserved.

关键词： Reinforcement learning

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MetAug: Contrastive Learning via Meta Feature Augmentation

arXiv

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arXiv 2022年

作者： Li, Jiangmeng Qiang, Wenwen Zheng, Changwen Su, Bing Xiong, Hui Science & Technology on Integrated Information System Laboratory Institute of Software Chinese Academy of Sciences Beijing China University of Chinese Academy of Sciences Beijing China Guangdong China Gaoling School of Artificial Intelligence Renmin University of China Beijing China Beijing Key Laboratory of Big Data Management and Analysis Methods Beijing China Guangzhou China Department of Computer Science Engineering The Hong Kong University of Science and Technology Hong Kong

What matters for contrastive learning? We argue that contrastive learning heavily relies on informative features, or "hard" (positive or negative) features. Early works include more informative features by applying complex data augmentations and large batch size or memory bank, and recent works design elaborate sampling approaches to explore informative features. The key challenge toward exploring such features is that the source multi-view data is generated by applying random data augmentations, making it infeasible to always add useful information in the augmented data. Consequently, the informativeness of features learned from such augmented data is limited. In response, we propose to directly augment the features in latent space, thereby learning discriminative representations without a large amount of input data. We perform a meta learning technique to build the augmentation generator that updates its network parameters by considering the performance of the encoder. However, insufficient input data may lead the encoder to learn collapsed features and therefore malfunction the augmentation generator. A new margin-injected regularization is further added in the objective function to avoid the encoder learning a degenerate mapping. To contrast all features in one gradient back-propagation step, we adopt the proposed optimization-driven unified contrastive loss instead of the conventional contrastive loss. Empirically, our method achieves state-of-the-art results on several benchmark datasets. Copyright © 2022, The Authors. All rights reserved.

关键词： Backpropagation

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TAG: Task-based Accumulated Gradients for Lifelong learning

arXiv

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arXiv 2021年

作者： Malviya, Pranshu Ravindran, Balaraman Chandar, Sarath Department of Computer and Software Engineering Mila - Quebec AI Institute École Polytechnique de Montréal Montréal Canada Robert Bosch Center for Data Science and Artificial Intelligence Department of Computer Science and Engineering IIT Madras Chennai India

When an agent encounters a continual stream of new tasks in the lifelong learning setting, it leverages the knowledge it gained from the earlier tasks to help learn the new tasks better. In such a scenario, identifying an efficient knowledge representation becomes a challenging problem. Most research works propose to either store a subset of examples from the past tasks in a replay buffer, dedicate a separate set of parameters to each task or penalize excessive updates over parameters by introducing a regularization term. While existing methods employ the general task-agnostic stochastic gradient descent update rule, we propose a task-aware optimizer that adapts the learning rate based on the relatedness among tasks. We utilize the directions taken by the parameters during the updates by additively accumulating the gradients specific to each task. These task-based accumulated gradients act as a knowledge base that is maintained and updated throughout the stream. We empirically show that our proposed adaptive learning rate not only accounts for catastrophic forgetting but also exhibits knowledge transfer. We also show that our method performs better than several state-of-the-art methods in lifelong learning on complex datasets. Moreover, our method can also be combined with the existing methods and achieve substantial improvement in performance. Copyright © 2021, The Authors. All rights reserved.

关键词： Knowledge representation

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Interventional Contrastive Learning with Meta Semantic Regularizer

arXiv

引用

arXiv 2022年

作者： Qiang, Wenwen Li, Jiangmeng Zheng, Changwen Su, Bing Xiong, Hui Science & Technology on Integrated Information System Laboratory Institute of Software Chinese Academy of Sciences Beijing China University of Chinese Academy of Sciences Beijing China Guangdong China Gaoling School of Artificial Intelligence Renmin University of China Beijing China Beijing Key Laboratory of Big Data Management and Analysis Methods Beijing China Guangzhou China Department of Computer Science & Engineering The Hong Kong University of Science and Technology Hong Kong

Contrastive learning (CL)-based self-supervised learning models learn visual representations in a pairwise manner. Although the prevailing CL model has achieved great progress, in this paper, we uncover an ever-overlooked phenomenon: When the CL model is trained with full images, the performance tested in full images is better than that in foreground areas;when the CL model is trained with foreground areas, the performance tested in full images is worse than that in foreground areas. This observation reveals that backgrounds in images may interfere with the model learning semantic information and their influence has not been fully eliminated. To tackle this issue, we build a Structural Causal Model (SCM) to model the background as a confounder. We propose a backdoor adjustment-based regularization method, namely Interventional Contrastive Learning with Meta Semantic Regularizer (ICL-MSR), to perform causal intervention towards the proposed SCM. ICL-MSR can be incorporated into any existing CL methods to alleviate background distractions from representation learning. Theoretically, we prove that ICL-MSR achieves a tighter error bound. Empirically, our experiments on multiple benchmark datasets demonstrate that ICL-MSR is able to improve the performances of different state-of-the-art CL methods. Copyright © 2022, The Authors. All rights reserved.

关键词： Semantics

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A heterogeneous group CNN for image super-resolution

arXiv

引用

arXiv 2022年

作者： Tian, Chunwei Zhang, Yanning Zuo, Wangmeng Lin, Chia-Wen Zhang, David Yuan, Yixuan The School of Software Northwestern Polytechnical University Shaanxi Xi’an710129 China The National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology Shaanxi Xi’an710129 China The School of Computer Science Northwestern Polytechnical University The National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology Shaanxi Xi’an710129 China The School of Computer Science and Technology Harbin Institute of Technology Heilongjiang Harbin150001 China The Department of Electrical Engineering The Institute of Communications Engineering National Tsing Hua University Hsinchu Taiwan Guangdong Shenzhen518172 China The Shenzhen Institute of Artificial Intelligence and Robotics for Society Shenzhen China The Department of Electronic Engineering The Chinese University of Hong Kong Hong Kong

Convolutional neural networks (CNNs) have obtained remarkable performance via deep architectures. However, these CNNs often achieve poor robustness for image superresolution (SR) under complex scenes. In this paper, we present a heterogeneous group SR CNN (HGSRCNN) via leveraging structure information of different types to obtain a high-quality image. Specifically, each heterogeneous group block (HGB) of HGSRCNN uses a heterogeneous architecture containing a symmetric group convolutional block and a complementary convolutional block in a parallel way to enhance internal and external relations of different channels for facilitating richer low-frequency structure information of different types. To prevent appearance of obtained redundant features, a refinement block with signal enhancements in a serial way is designed to filter useless information. To prevent loss of original information, a multi-level enhancement mechanism guides a CNN to achieve a symmetric architecture for promoting expressive ability of HGSRCNN. Besides, a parallel up-sampling mechanism is developed to train a blind SR model. Extensive experiments illustrate that the proposed HGSRCNN has obtained excellent SR performance in terms of both quantitative and qualitative analysis. Codes can be accessed at https://***/hellloxiaotian/HGSRCNN. © 2022, CC BY-NC-SA.

关键词： Convolutional neural networks

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Shape-aware contrastive deep supervision for esophageal tumor segmentation from CT scans

Shape-aware contrastive deep supervision for esophageal tumo...

引用

IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

作者： Qiangguo Jin Hui Cui Changming Sun Jiapeng Huang Ping Xuan Yiyue Xu Linlin Wang Leilei Cao Leyi Wei Ran Su School of Software Northwestern Polytechnical University Shaanxi China Yangtze River Delta Research Institute of Northwestern Polytechnical University Taicang China Department of Computer Science and Information Technology La Trobe University Melbourne Australia CSIRO Data61 Sydney Australia Department of Computer Science School of Engineering Shantou University Guangdong China Department of Radiation Oncology Shandong Cancer Hospital and Institute Shandong First Medical University and Shandong Academy of Medical Sciences Shandong China Innovation Center of Yangtze River Delta Zhejiang University Zhejiang China School of Software Shandong University Shandong China School of Computer Software College of Intelligence and Computing Tianjin University Tianjin China

Accurate tumor segmentation is crucial for esophageal cancer radiotherapy treatment planning. The low contrast among the esophagus, tumors, and surrounding tissues, and irregular tumor shapes limit the performance of automatic segmentation methods. In this paper, we aim to exploit the irregular shapes of tumors to facilitate accurate segmentation. We propose a simple and pluggable shape-aware contrastive deep supervision network (SCDSNet) with shape-aware regularization and voxel-to-voxel contrastive deep supervision. Specifically, the shape-aware regularization with an uncertainty minimization strategy encourages the precise predictions of an additional shape-aware head. The voxel-to-voxel contrastive deep supervision enhances the multi-scale shape-tumor contrast for better voxel-to-voxel prediction of shapes. The proposed method is simple and highly pluggable, which can easily be extended to other frameworks. Further, we establish a large in-house dataset on esophageal cancer to validate the effectiveness of our proposed method. The quantitative and qualitative experimental results demonstrate the effectiveness of SCDSNet on the esophageal cancer dataset.

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Structure Embedded Nucleus Classification for Histopathology Images

arXiv

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arXiv 2023年

作者： Lou, Wei Wan, Xiang Li, Guanbin Lou, Xiaoying Li, Chenghang Gao, Feng Li, Haofeng Shenzhen Research Institute of Big Data Guangdong Provincial Key Laboratory of Big Data Computing The Chinese University of Hong Kong at Shenzhen Shenzhen518172 China Pazhou Lab Guangzhou510330 China The School of Computer Science and Engineering Sun Yat-sen University Guangzhou510006 China Department of Pathology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou China Artificial Intelligence Thrust The Hong Kong University of Science and Technology at Guangzhou Guangzhou510030 China Department of Colorectal Surgery Department of General Surgery Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital Sun Yat-sen University Guangzhou510655 China Shanghai Artificial Intelligence Laboratory Shanghai China

Nuclei classification provides valuable information for histopathology image analysis. However, the large variations in the appearance of different nuclei types cause difficulties in identifying nuclei. Most neural network based methods are affected by the local receptive field of convolutions, and pay less attention to the spatial distribution of nuclei or the irregular contour shape of a nucleus. In this paper, we first propose a novel polygon-structure feature learning mechanism that transforms a nucleus contour into a sequence of points sampled in order, and employ a recurrent neural network that aggregates the sequential change in distance between key points to obtain learnable shape features. Next, we convert a histopathology image into a graph structure with nuclei as nodes, and build a graph neural network to embed the spatial distribution of nuclei into their representations. To capture the correlations between the categories of nuclei and their surrounding tissue patterns, we further introduce edge features that are defined as the background textures between adjacent nuclei. Lastly, we integrate both polygon and graph structure learning mechanisms into a whole framework that can extract intra and inter-nucleus structural characteristics for nuclei classification. Experimental results show that the proposed framework achieves significant improvements compared to the state-of-the-art methods. Copyright © 2023, The Authors. All rights reserved.

关键词： Classification (of information)

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