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7th International Conference on Information Management and Technology, ICIMTech 2022

作者： Rahutomo, Reza Elwirehardja, Gregorius Natanael Dominic, Nicholas Caesario, Benedict Pardamean, Bens School of Information Systems Bina Nusantara University Information Systems Department Jakarta11480 Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia BINUS Graduate Program - Master of Computer Science Bina Nusantara University Computer Science Department Jakarta11480 Indonesia

ISBN: (数字)9781665450904

ISBN: (纸本)9781665450904

The launch of StuntingDB is believed to enliven the role of database management systems (DBMS) in Indonesia's stunting research. However, a novelty in stunting data management that enables parallel project activation in multiple observation areas is necessary. Several improved functionalities in StuntingDB must be designed to prevent the high demand for accessibility in the middle of stunting research. Connolly and Begg's principle of database design is adopted along with Software Development Life Cycle's Waterfall model for creating a continuous development of the system. This research produces a new database design in the form of Entity Relationship Diagram (ERD) and Use Case Diagram to help system developers realizing a new version of StuntingDB for stunting research in several observation areas. © 2022 IEEE.

关键词： database systems

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Quantum variational autoencoder utilizing regularized mixed-state latent representations

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Physical Review A 2025年第4期111卷 042416-042416页

作者： Gaoyuan Wang Jonathan Warrell Prashant S. Emani Mark Gerstein Program in Computational Biology and Bioinformatics Yale University New Haven Connecticut 06520 USA Department of Molecular Biophysics and Biochemistry Yale University New Haven Connecticut 06520 USA NEC Laboratories America Princeton New Jersey 08540 USA Department of Computer Science Yale University New Haven Connecticut 06520 USA Department of Statistics & Data Science Yale University New Haven Connecticut 06520 USA Department of Biomedical Informatics & Data Science Yale University New Haven Connecticut 06520 USA

A major challenge in near-term quantum computing is its application to large real-world datasets due to scarce quantum hardware resources. One approach to enabling tractable quantum models for such datasets involves finding low-dimensional representations that preserve essential information for downstream analysis. In classical machine learning, variational autoencoders (VAEs) facilitate efficient data compression, representation learning for subsequent tasks, and novel data generation. However, no quantum model has been proposed that exactly captures all of these features for direct application to quantum data on quantum computers. Some existing quantum models for data compression lack regularization of latent representations, thus preventing direct use for generation and control of generalization. Others are hybrid models with only some internal quantum components, impeding direct training on quantum data. To address this, we present a fully quantum framework, ζ-QVAE, which encompasses all the capabilities of classical VAEs and can be directly applied to map both classical and quantum data to a lower-dimensional space, while effectively reconstructing much of the original state from it. Our model utilizes regularized mixed states to attain optimal latent representations. It accommodates various divergences for reconstruction and regularization. Furthermore, by accommodating mixed states at every stage, it can utilize the full data density matrix and allow for a training objective defined on probabilistic mixtures of input data. Doing so, in turn, makes efficient optimization possible and has potential implications for private and federated learning. In addition to exploring the theoretical properties of ζ-QVAE, we demonstrate its performance on representative genomics and synthetic data. Our results indicate that ζ-QVAE consistently learns representations that better utilize the capacity of the latent space and exhibits similar or better performance compared with

关键词： Quantum computers

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Machine Learning Approaches in Detecting Autism Spectrum Disorder

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Procedia Computer science 2023年 227卷 1070-1076页

作者： Daniel Nicholas Dominic Tjeng Wawan Cenggoro Bens Pardamean Computer Science Department BINUS Graduate Program – Master of Computer Science Program Bina Nusantara University Jakarta Indonesia 11480 Computer Science Department School of Computer Science Bina Nusantara University Jakarta Indonesia 11480 Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia 11480

Early detection of Autism Spectrum Disorder (ASD) needs to be increased to prevent further adverse impacts. Thus, the classifi-cation between ASD and Typically Development (TD) individuals is an intriguing task. This review study has collected 26 related papers to answer four research questions, i.e., what are the most used data inputs, brain atlases, and machine learning models for ASD classification, as also to discover the significant parts of the brain correlated with the ASD. It was eventually found that functional connectivity matrix, Support Vector Machine, and CC200 are the most frequently used data input, model, and brain atlas, respectively. Researchers also concluded that the posterior temporal fusiform cortex, intracalcarine cortex, cuneal cortex, subcallosal cortex, occipital pole, and lateral occipital cortex are the brain regions highly correlated with ASD.

关键词： autism spectrum disorder brain atlas brain region machine learning

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Sentiment Analysis for TikTok Review Using VADER Sentiment and SVM Model

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Procedia Computer science 2023年 227卷 168-175页

作者： Mahmud Isnan Gregorius Natanael Elwirehardja Bens Pardamean Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta 11480 Indonesia Computer Science Department School of Computer Science Bina Nusantara University Jakarta 11480 Indonesia Computer Science Department BINUS Graduate Program – Master of Computer Science Program Bina Nusantara University Jakarta 11480 Indonesia

TikTok, a social networking site for uploading short videos, has become one of the most popular. Despite this, not all users are happy with the app; there are criticisms and suggestions, one of which is reviewed via the TikTok app on the Google Play Store. The reviews were extracted and then used for training a sentiment analysis model. The VADER sentiment method was utilized to offer the review's initial labeling (positive, neutral, and negative). The result revealed that most reviews were classified as positive, meaning that the data were imbalanced and challenging to handle in further analysis. Therefore, Random Under-sampling (RUS) and Random Over-sampling (ROS) methods were deployed to deal with that condition. The labeled reviews were subsequently pre-processed using tools such as case folding, noise removal, normalization, and stopwords before being used for training a Support Vector Machine (SVM) model for sentiment classification. The SVM trained without resampling produced the most favorable results, with an F1-score of 0.80.

关键词： Sentiment Analysis TikTok SVM VADER Sentiment Google Play Store

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The Technology behind Genomic database 4

The Technology behind Genomic Database

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4th International Conference on Cybernetics and Intelligent System, ICORIS 2022

作者： Trinugroho, Joko Pebrianto Perbangsa, Anzaludin Samsinga Pardamean, Bens Bina Nusantara University Bioinformatics and Data Science Research Center Jakarta11480 Indonesia School of Information Systems Bina Nusantara University Information Systems Department Jakarta11480 Indonesia Bina Nusantara University BINUS Graduate Program - Master of Computer Science Computer Science Department Jakarta11480 Indonesia

ISBN: (纸本)9781665453950

In this digital era, we are exposed to a large amount of data. This includes biological data, which stores information about living organisms, including Deoxyribonucleic acid (DNA), genes, and proteins. With the development of information technology and information system, most of available biological data are stored in an online public database. Many of the databases are free-access and easily used, which helps the users, especially researchers, to make use of the data. Among the known public biological databases are the University of California Santa Cruz (UCSC) Genome Browser database and the Rat Genome database (RGD). These two databases provide access to the biological data from different organisms. This paper aims to describe the technology of public biological databases. Also elucidated in this paper are the differences features between UCSC Genome Browser database and the RGD. Our results showed that the UCSC contains much more biological data and features than the RGD. However, the genome browser of UCSC has a complex display, while the RGD has a simple display. Overall, both databases give the users the option to choose the most suitable database for them. © 2022 IEEE.

关键词： Rats

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Kirigami: large convolutional kernels improve deep learning-based RNA secondary structure prediction

arXiv

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arXiv 2024年

作者： Harary, Marc Zhang, Chengxin Department of Data Science Dana-Farber Cancer Institute BostonMA02115 United States Department of Computational Medicine and Bioinformatics University of Michigan Ann ArborMI48109 United States

We introduce a novel fully convolutional neural network (FCN) architecture for predicting the secondary structure of ribonucleic acid (RNA) molecules. Interpreting RNA structures as weighted graphs, we employ deep learning to estimate the probability of base pairing between nucleotide residues. Unique to our model are its massive 11-pixel kernels, which we argue provide a distinct advantage for FCNs on the specialized domain of RNA secondary structures. On a widely adopted, standardized test set comprised of 1,305 molecules, the accuracy of our method exceeds that of current state-of-the-art (SOTA) secondary structure prediction software, achieving a Matthews Correlation Coefficient (MCC) over 11-40% higher than that of other leading methods on overall structures and 58-400% higher on pseudoknots specifically. © 2024, CC BY.

关键词： RNA

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Machine Learning Approach for Single Nucleotide Polymorphism Selection in Genetic Testing Results

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Procedia Computer science 2023年 227卷 46-54页

作者： Joko Pebrianto Trinugroho Alam Ahmad Hidayat Mahmud Isnan Bens Pardamean Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta 11480 Indonesia Department of Mathematics School of Computer Science Bina Nusantara University Jakarta 11480 Indonesia Computer Science Department BINUS Graduate Program Bina Nusantara University Jakarta 11480 Indonesia

Lactose intolerance is a type of digestive problem that may threaten the population because milk and dairy products compose of nutrients that are essential for human body. Genetic tests possess a great potential to detect lactose intolerance as it can be used in children and even infants. However, a new approach to analyze the genetic test results is needed to elucidate the Single Nucleotide Polymorphisms (SNPs) that are related to lactose intolerance. In this work, we utilized the machine learning based feature selection to select the SNPs associated with lactose tolerance trait from genotyping samples of direct-to-customer (DTCG genetic tests, obtained from the public database. Recursive Feature Elimination (RFE) with XGBoost model was used to perform feature selection. We also compared three different models, such as XGBoost, support vector machine (SVM), and random forest (RF) for training the selected features. Our findings revealed that 20 SNPs (out of 3501) were chosen, with rs4394668 as the most important variables (F-score 0.009). Furthermore, when compared to the RF and SVM models, the XGBoost model had the highest accuracy (0.87). Further studies should be undertaken to elucidate how the selected SNPs may lead to the lactose intolerance trait.

关键词： lactose intolerance SNP genetic test feature selection

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m6A peak calling accounting for varying sequencing bias across regions and samples

m6A peak calling accounting for varying sequencing bias acro...

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IEEE International Conference on bioinformatics and Biomedicine (BIBM)

作者： Lanyu Zhang Zhenxing Guo Zhaohui Qin Zhijin Wu Dept of Biostatistics Brown University Providence RI USA School of Data Science The Chinese University of Hong Kong Shenzhen China Dept of Biostatistics and Bioinformatics Emory University Atlanta Georgia USA

ISBN: (数字)9798350386226

ISBN: (纸本)9798350386233

N 6 -Methyladenosine (m 6 A) is the most abundant type of mRNA methylation and is most widely measured by methylated RNA immunoprecipitation sequencing (MeRIP-seq). In MeRIP-seq, an immunoprecipitation (IP) sample and a pairing control (input) sample are sequenced for each biological sample. Methylated regions are identified as peaks showing increased counts in the IP sample versus the input. We report that technical bias in sequencing can vary substantially in the IP and input samples depending on the local sequence context. Current sequencing depth-based normalization does not appropriately account for the varying technical bias along the transcriptome and leads to inaccurate identification of m 6 A regions. We describe a method to estimate a local size factor that reflects the RNA sequence context and show that peak calling using these region-specific size factors identifies more accurate peak regions.

关键词： Sequential analysis Accuracy RNA Biomedical measurement Biology IP networks bioinformatics Immune system

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data mining for epidemiology: The correlation of typhoid fever occurrence and environmental factors 7

Data mining for epidemiology: The correlation of typhoid fev...

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7th International Conference on Computer science and Computational Intelligence, CSCI 2022

作者： Asadi, Faisal Trinugroho, Joko Pebrianto Hidayat, Alam Ahmad Rahutomo, Reza Pardamean, Bens Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia Information System Department School of Information System Bina Nusantara University Jakarta11480 Indonesia Computer Science Department BINUS Graduate Program-Master of Computer Science Program Bina Nusantara University Jakarta 11480 Indonesia

Typhoid fever is an endemic disease that burdens Indonesia and has a potentially fatal infection multisystem. Salmonella typhi bacterium is responsible for typhoid fever disease. Poor sanitation, crowding, and slums are the main factors of increasing typhoid fever incidences. Environmental factors directly connected to meteorological factors are the main factor in breeding the Salmonella typhi bacterium. This study aims to identify the correlation between meteorological parameters and typhoid fever disease occurrence. The study was carried out in Jakarta, Indonesia, and the Bureau of Meteorological, Climatology, and Geophysics (BMKG) provided the meteorological parameter data. In addition, the Jakarta health surveillance office provided information on typhoid fever hospitalizations from 2019 to 2021. Pearson's concept was utilized d to investigate the correlation between typhoid fever incidences and the meteorological parameters. Humidity, precipitation, and wind speed are the meteorological parameters that significantly affect in contribute to the occurrence of typhoid fever disease. These findings might be used as a reference for Indonesia's government in making public policy to prevent typhoid fever in Indonesia. © 2022 Elsevier B.V.. All rights reserved.

关键词： data mining

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Scheme and Construction of a Smart Vacuum Cleaner Robot 3

Scheme and Construction of a Smart Vacuum Cleaner Robot

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3rd International Conference on Advances in Electrical, Computing, Communication and Sustainable Technologies, ICAECT 2023

作者： Hasan, Md. Ibrahim Zeyad, Mohammad Ahmed, S.M. Masum Tasrif Anubhove, Md. Sadik Hossain, Eftakhar Hasan, Sayeed Mahmud, Dewan Mahnaaz Advanced Bioinformatics Computational Biology and Data Science Laboratory Bangladesh Energy and Technology Research Division Chattogram4226 Bangladesh Erasmus+ Joint MSC in Smart Cities and Communities Heriot-Watt University Edinburgh United Kingdom Erasmus+ Joint MSC in Smart Cities and Communities Faculty of Engineering Mons Belgium

ISBN: (纸本)9781665494007

A smart vacuum robot is a remarkable technological achievement that makes cleaning more efficient, faster, and easier. According to this study, the smart vacuum cleaning robot can be operated manually, automatically, mopped/swept, vacuumed/vacuumed, and observed from 360°. A design of a smart vacuum-cleaning robot is proposed with different characteristics. The Arduino IDE and Proteus Design Suite 8 Professional software were employed for analytical analysis, with a microcontroller serving as the primary control component. The hardware implementation comprises a microcontroller, ultrasonic sensor, and light-dependent resistor (LDR) where the ultrasonic sensor identifies obstacles (trash). Therefore, the LDR emits light and sends the microcontroller's signal to the microprocessor. All the sensors in the proposed system operated flawlessly during the experiment. Moreover, all the sensors were performing perfectly. With additional features of this robot, it can continue its operation during darkness. The proposed robot is equipped with a number of creative and intelligent features that allow it to provide the maximum possible support to employees, housewives, and ordinary people. This work presents a new notion of an advanced cleaning robot employing cutting-edge technology that can work independently in automated and regular situations and dramatically improve the cleaning system for humanity. © 2023 IEEE.

关键词： Microcontrollers

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