Near-Infrared Spectroscopy (NIRS) is an effective technique for monitoring cerebral hemodynamics and oxygenation. We report a study of the cerebral hemoglobin concentration changes during electro- convulsive therapy (...
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In this paper we present a new, adaptive spatial-derivative circuit for CMOS image sensors. The circuit removes its offset as a natural part of its operation using a combination of electron tunneling and hot-electron ...
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In this paper we present a new, adaptive spatial-derivative circuit for CMOS image sensors. The circuit removes its offset as a natural part of its operation using a combination of electron tunneling and hot-electron injection to add or remove charge on a floating-gate of an auto-zeroing amplifier. We designed, fabricated and successfully tested a chip with the circuit. Test results show that the circuit reduces the offsets by more than an order of magnitude.
We present a second-derivative scheme of image processing to enhance the detection of regions of higher absorbance in optical mammograms. The second-derivative images facilitate a spectral analysis that estimates the ...
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In this paper we present the recent technological development of optical coherence tomography (OCT). We also discuss the potential clinical applications of OCT for diagnosing pathological changes in different organs a...
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In this paper we present the recent technological development of optical coherence tomography (OCT). We also discuss the potential clinical applications of OCT for diagnosing pathological changes in different organs and systems.
Biomedical image registration often requires local elastic matching after initial global alignment. Due to their universal approximation property, neural networks may be used for landmark-based elastic registration. A...
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Biomedical image registration often requires local elastic matching after initial global alignment. Due to their universal approximation property, neural networks may be used for landmark-based elastic registration. A supervised learning approach using backpropagation, Bayesian regularization, Gauss-sigmoid networks, and radial basis function networks is presented for 2D elastic registration.
This paper presents a novel approach to ultrasound backscatter characterization based on generalized entropy. This approach makes no assumptions about the specific scattering distribution. Low order Renyi and Tsallis ...
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This paper presents a novel approach to ultrasound backscatter characterization based on generalized entropy. This approach makes no assumptions about the specific scattering distribution. Low order Renyi and Tsallis entropies have a higher dynamic range than Shannon entropy over a range of scattering conditions, and are therefore useful in estimating scatterer density and regularity. A neural network estimator is constructed to illustrate the validity of this approach.
The juxtaposition of computation and biology opens up a new world of science and technology. Richard Feynman characterizes the young and fast-developing world of computerscience as follows: "[it] is like enginee...
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The juxtaposition of computation and biology opens up a new world of science and technology. Richard Feynman characterizes the young and fast-developing world of computerscience as follows: "[it] is like engineering-it is all about getting something to do something."1 Viewed from this perspective, the scope of research and development at this intersection is a vast, two-way street that computerscience has to offer to biological science and biotechnology and vice versa. Computational thinking helps characterize, predict, and influence the dynamics of biological processes from molecular to cellular to organ in a way that revolutionizes our understanding of health and drug design. In turn, understanding the architecture and principles of natural biological processes and organization might require new models of computation, which could lead to robustness in the design of large-scale software and hardware systems, a hitherto elusive goal.
Bragg gratings fabricated on top of ion exchanged glass waveguides using PECVD-deposited silicon overlays are reported. The resulting Bragg gratings are characterized and transmission dips at 1536 nm in excess of 18 d...
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The effects of exercise, nutrition, and aging on the development of human skeletal muscles can be observed from the morphological changes of the Z-band under the electron microscope. Quantification of the Z-band damag...
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