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Longitudinal, Multimodal Tracking Reveals Lasting Neurovascular Impact of Individual Microinfarcts

Advanced science 2025年第0期12卷 e2417003页

作者： Jin, Yifu He, Fei Rathore, Haad Sun, Yingchu Zhang, Jia-ao Li, Xinyu Yin, Rongkang Zhu, Hanlin Xie, Chong Luan, Lan Department of Electrical and Computer Engineering Rice University HoustonTX77005 United States Neuroengineering Initiative Rice University HoustonTX77005 United States Applied Physics Program Rice University HoustonTX77005 United States Department of Bioengineering Rice University HoustonTX77005 United States

Microinfarcts, the "invisible lesions", are prevalent in aged and injured brains and associated with cognitive impairments, yet their neurophysiological impact remains largely unknown. Using a multimodal chronic neural platform that combines functional microvasculature imaging with spatially resolved neural recording, the neurovascular effect of a single microinfarct is investigated. Unlike larger strokes, microinfarcts induced only temporary suppression of neural activity with minimal cell death, with recovery paralleling vasculature remodeling at the infarct core. Neural activity is more severely suppressed at the shallower cortical layer despite milder vascular damage compared to deeper layers, and the excitability of fast-spiking interneurons attenuation is accompanied by heightened bursting of regular spiking neurons. Spike phase locking at the low-gamma band is disrupted, indicating a lasting impairment of long-range assembly communication. These results highlight the subtle yet significant neurovascular disruptions of a single microinfarct. © 2025 The Author(s). Advanced science published by Wiley-VCH GmbH.

关键词： Flexible electronics

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Ultrathin-shell epitaxial Ag@Au core-shell nanowires for high-performance and chemically-stable electronic, optical, and mechanical devices

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Nano Research 2021年第11期14卷 4294-4303页

作者： Yangzhi Zhu Sanggon Kim Xuezhi Ma Peter Byrley Ning Yu Qiushi Liu Xiaoming Sun Da Xu Sangshan Peng Martin C.Hartel Shiming Zhang Vadim Jucaud Mehmet R.Dokmeci Ali Khademhosseini Ruoxue Yan Department of Chemical and Environmental Engineering Bourns College of EngineeringUniversity of California-RiversideRiversideCA92521USA Terasaki Institute for Biomedical Innovation Los AngelesCA90064USA Department of Electrical and Computer Engineering University of California-RiversideRiversideCA92521USA State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical TechnologyBeijing100029China State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha410082China Department of Bioengineering University of California-Los AngelesLos AngelesCA90095USA Department of Electrical and Electronic Engineering The University of Hong KongHong KongChina Material Science and Engineering Program University of California-RiversideRiversideCA92521USA

Silver nanowires (AgNWs) hold great promise for applications in wearable electronics, flexible solar cells, chemical and biological sensors, photonic/plasmonic circuits, and scanning probe microscopy (SPM) due to their unique plasmonic, mechanical, and electronic properties. However, the lifetime, reliability, and operating conditions of AgNW-based devices are significantly restricted by their poor chemical stability, limiting their commercial potentials. Therefore, it is crucial to create a reliable oxidation barrier on AgNWs that provides long-term chemical stability to various optical, electrical, and mechanical devices while maintaining their high performance. Here we report a room-temperature solution-phase approach to grow an ultra-thin, epitaxial gold coating on AgNWs to effectively shield the Ag surface from environmental oxidation. The Ag@Au core-shell nanowires (Ag@Au NWs) remain stable in air for over six months, under elevated temperature and humidity (80 °C and 100% humidity) for twelve weeks, in physiological buffer solutions for three weeks, and can survive overnight treatment of an oxidative solution (2% H2O2). The Ag@Au core-shell NWs demonstrated comparable performance as pristine AgNWs in various electronic, optical, and mechanical devices, such as transparent mesh electrodes, surface-enhanced Raman spectroscopy (SERS) substrates, plasmonic waveguides, plasmonic nanofocusing probes, and high-aspect-ratio, high-resolution atomic force microscopy (AFM) probes. These Au@Ag core-shell NWs offer a universal solution towards chemically-stable AgNW-based devices without compromising material property or device performance.

关键词： epitaxial growth core-shell nanowire plasmonic waveguides atomic force microscopy(AFM)probe transparent electrode wearable electronics

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Automated classification of renal tumors on ultrasound images using deep neural network

Automated classification of renal tumors on ultrasound image...

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International Symposium on Environmentally Conscious Design and Inverse Manufacturing (EcoDesign)

作者： Wei-Chieh Wu Te-Mei Chiang Zhi-Ren Tsai Program in Artificial Intelligence College of Information and Electrical Engineering Asia University Taichung City Taiwan Department of Radiation Oncology Asia University Hospital Taichung City Taiwan Department of Computer Science & Information Engineering Asia University

ISBN: (数字)9798350363043

ISBN: (纸本)9798350363050

Kidney cancer is one of the most common cancers worldwide. The major types of malignant renal tumors are renal cell carcinoma and urothelial carcinoma. Although the majority of renal tumors are malignant, up to $20\%$ are benign, most commonly renal cyst and angiomyolipomas. Ultrasound is the most accessible imaging tool in medical practice, but it highly depends on operator skill, which may lead to high false-negative rate in diagnosis. The purpose of this study was to develop a predictive model for the automated classification of renal tumors on ultrasound images using deep neural network. A total of 880 kidney ultrasound images were used for training and testing. Transfer learning was used to the ten Convolution neural network models. The kidney ultrasound images were classified as benign or malignant tumors. The classification performance of the model was evaluated by sensitivity and specificity. The research results show that VGG18 yielded the best performance, with a sensitivity of $79 \%$, and a specificity of $86 \%$.

关键词： Training Ultrasonic imaging Sensitivity Convolution Transfer learning Artificial neural networks Sensitivity and specificity Kidney Cancer Testing

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Investigation of neurovascular coupling in four vigilance states of the human brain by simultaneous EEG-fNIRS measurement and wavelet coherence analysis

Investigation of neurovascular coupling in four vigilance st...

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Optics and the Brain, BRAIN 2021 - Part of Biophotonics Congress: Optics in the Life sciences 2021

作者： Rabbani, Parisa Wang, Xinlong Babawale, Olajide Kim, Jae Gwan Liu, Hanli University of Texas at Arlington Department of Bioengineering ArlingtonTX76010 United States Gwangju Institute of Science and Technology School of Electrical Engineering and Computer Science Gwangju61005 Korea Republic of

We conducted wavelet coherence analysis to quantify/image the cerebral neurovascular coupling at infra-slow frequencies during four different awake-to-sleep vigilance states using whole-head, simultaneous EEG and func... 详细信息

ISBN: (纸本)9781557528209

关键词： Infrared devices

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Design and Development of Low-cost Wearable Electroencephalograms (EEG) Headset

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Intelligent Automation & Soft Computing 2023年第3期35卷 2821-2835页

作者： Riaz Muhammad Ahmed Ali M.Abid Anwar Toufique Ahmed Soomro Omar AlShorman Adel Alshahrani Mahmoud Masadeh Ghulam Md Ashraf Naif H.Ali Muhammad Irfan Athanasios Alexiou Department of Electrical Engineering Sukkur IBA University65200SukkurPakistan Department of Electronic Engineering Quaid-e-Awam University of EngineeringScience and TechnologyLarkana77150Pakistan Faculty of Engineering and AlShrouk Trading Company Najran UniversityNajran61441Saudi Arabia Department of Medical Rehabilitation Sciences-Physiotherapy Program College of Applied Medical SciencesNajran UniversityNajran61441Saudi Arabia Computer Engineering Department Yarmouk UniversityIrbid21163Jordan Pre-Clinical Research Unit King Fahd Medical Research CenterKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Medical Laboratory Technology Faculty of Applied Medical SciencesKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Internal Medicine Medical CollegeNajran UniversityNajran61441Saudi Arabia Electrical Engineering Department College of EngineeringNajran University Saudi ArabiaNajran61441Saudi Arabia Novel Global Community Educational Foundation HebershamNSW 2770AustraliaAFNP Med AustriaWien2770Austria

Electroencephalogram(EEG)is a method of capturing the electrophy-siological signal of the *** EEG headset is a wearable device that records electrophysiological data from the *** paper presents the design and fab-rication of a customized low-cost Electroencephalogram(EEG)headset based on the open-source OpenBCI Ultracortex Mark IV *** electrode placement locations are modiﬁed under a 10–20 standard *** fabricated headset is then compared to commercially available headsets based on the following para-meters:affordability,accessibility,noise,signal quality,and ***,the data is recorded from 20 subjects who used the EEG Headset,and signals were ***,the participants marked the accuracy,set up time,participant comfort,and participant perceived ease of set-up on a scale of 1 to 7(7 being excellent).Thirdly,the self-designed EEG headband is used by 5 participants for slide *** raw EEG signal is decomposed into a series of band sig-nals using discrete wavelet transform(DWT).Lastly,theseﬁndings have been compared to previously reported *** concluded that when used for slide-changing control,our self-designed EEG headband had an accuracy of 82.0 *** also concluded from the results that our headset performed well on the cost-effectiveness scale,had a reduced setup time of 2±0.5 min(the short-est among all being compared),and demonstrated greater ease of use.

关键词： Brain-computer interface EEG consumer-grade accessibility headset

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CLINICAL DETERIORATION PREDICTION IN BRAZILIAN HOSPITALS BASED ON ARTIFICIAL NEURAL NETWORKS AND TREE DECISION MODELS 15

CLINICAL DETERIORATION PREDICTION IN BRAZILIAN HOSPITALS BAS...

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15th International Conference on ICT, Society and Human Beings, ICT 2022, 19th International Conference on Web Based Communities and Social Media, WBC 2022 and 14th International Conference on e-Health, EH 2022 - Held at the 16th Multi Conference on computer science and Information Systems, MCCSIS 2022

作者： Yazdanpanah, Hamed Silva, Augusto C.M. Guedes, Murilo Morales, Hugo M.P. dos Coelho, Leandro S. Moro, Fernando G. Department of Research Robô Laura PR Curitiba Brazil Department of Computer Science University of São Paulo SP São Paulo Brazil Industrial and Systems Engineering Graduate Program Pontifical Catholic University of Parana PR Curitiba Brazil Electrical Engineering Graduate Program Federal University of Parana PR Curitiba Brazil

ISBN: (纸本)9789898704405

Early recognition of clinical deterioration (CD) has vital importance in patients’ survival from exacerbation or death. Electronic health records (EHRs) data have been widely employed in Early Warning Scores (EWS) to measure CD risk in hospitalized patients. Recently, EHRs data have been utilized in Machine Learning (ML) models to predict mortality and CD. The ML models have shown superior performance in CD prediction compared to EWS. Since EHRs data are structured and tabular, conventional ML models are generally applied to them, and less effort is put into evaluating the artificial neural network’s performance on EHRs data. Thus, in this article, an extremely boosted neural network (XBNet) is used to predict CD, and its performance is compared to eXtreme Gradient Boosting (XGBoost) and random forest (RF) models. For this purpose, 103,105 samples from thirteen Brazilian hospitals are used to generate the models. Moreover, the principal component analysis (PCA) is employed to verify whether it can improve the adopted models’ performance. The performance of ML models and Modified Early Warning Score (MEWS), an EWS candidate, are evaluated in CD prediction regarding the accuracy, precision, recall, F1-score, and geometric mean (G-mean) metrics in a 10-fold cross-validation approach. According to the experiments, the XGBoost model obtained the best results in predicting CD among Brazilian hospitals’ data. © 2022 15th International Conference on ICT, Society and Human Beings, ICT 2022, 19th International Conference on Web Based Communities and Social Media, WBC 2022 and 14th International Conference on e-Health, EH 2022 - Held at the 16th Multi Conference on computer science and Information Systems, MCCSIS 2022. All rights reserved.

关键词： Neural networks

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A Genetic Algorithm to Optimize Cargo Stability in Container Transportation 11

A Genetic Algorithm to Optimize Cargo Stability in Container...

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11th IEEE Global Conference on Consumer Electronics, GCCE 2022

作者： Hsieh, Chi-Jung Wu, Kuang-Sung Wu, Tin-Yu Tey, Fu Jie Chen, Yi-Kai Ho, Jye Yi National Ilan University Department of Computer Science and Information Engineering Ilan County Taiwan National Ilan University Master Program of E-Learning for Multimedia and Network Communications Yilan Taiwan National Pingtung University of Science and Technology Department of Management Information Systems Pingtung County Taiwan National Taiwan University of Science and Technology Department of Electrical Engineering Taipei Taiwan

ISBN: (纸本)9781665492324

In the era of the global village, frequent cross-border trade in goods has made container transportation a significant part in delivery of cargo. However, rollover accidents of container trucks often occur because of tall truck height, improper cargo stowage or crooked roads. Therefore, how to find the optimal center of gravity (CG) of the packed cargo remains an issue that the transportation industry should not neglect. To optimize cargo stability and reduce the incidence of rollovers, this paper proposes a genetic algorithm that scores the cargo stacking process to find the best CG of the cargo based on the CG of the vehicle. According to the deviation angle and the point closest to the best CG, we can Figure out the optimal cargo stacking method. © 2022 IEEE.

关键词： Genetic algorithms

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Global distribution of forest classes and leaf biomass for use as alternative foods to minimize malnutrition

World Food Policy

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World Food Policy 2021年第2期7卷 128-146页

作者： Fist, Tim Adesanya, Adewale A. Denkenberger, David Pearce, Joshua M. Alliance to Feed the Earth in Disasters (ALLFED) Environmental and Energy Program Social Science Department Michigan Technological University Department of Mechanical Engineering University of Alaska Fairbanks Department of Electrical and Computer Engineering Western University

Due to the ready availability of tree leaves in many geographies, the alternative food of leaf concentrate currently has the potential to alleviate hunger in over 800 million people. It is therefore potentially highly impactful to determine the edibility of leaf concentrates, which are in the same regions as the world's most undernourished populations. Unfortunately, the toxicity of leaf concentrate for most common tree leaf types has not been screened and the cost of doing so demands a prioritization. This preliminary study explores this potential solution to world hunger by finding the forest classes most likely to offer proximate access to the world's hungry, thus providing the basis for a prioritized list of leaf types to screen for toxicity. Specifically, this study describes a novel methodology for mapping available green leaf biomass and corresponding forest classes (e.g., tropical moist deciduous forest), and their spatial relationship to the global distribution of people who are underweight. These results will be useful for developing a targeted list of tree species to conduct leaf toxicity analysis on, in the interest of developing leaves as an alternative food source for both current malnutrition problems and global catastrophic scenarios. © 2021 Policy Studies Organization.

关键词： agriculture edible leaves forests GIS global catastrophic risk hunger

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DART: Deformable Anatomy-Aware Registration Toolkit for Lung CT Registration with Keypoints Supervision

DART: Deformable Anatomy-Aware Registration Toolkit for Lung...

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IEEE International Symposium on Biomedical Imaging

作者： Yunzheng Zhu Luoting Zhuang Yannan Lin Tengyue Zhang Hossein Tabatabaei Denise R Aberle Ashley E Prosper Aichi Chien William Hsu Department of Radiological Sciences Medical & Imaging Informatics David Geffen School of Medicine at UCLA Department of Electrical & Computer Engineering UCLA Samueli School of Engineering Medical Informatics Home Area UCLA Graduate Programs in Bioscience Department of Computer Science UCLA Samueli School of Engineering Department of Radiological Sciences David Geffen School of Medicine at UCLA Department of Bioengineering UCLA Samueli School of Engineering

ISBN: (数字)9798350313338

ISBN: (纸本)9798350313345

Spatially aligning two computed tomography (CT) scans of the lung using automated image registration techniques is a challenging task due to the deformable nature of the lung. However, existing deep-learning-based lung CT registration models are not trained with explicit anatomical knowledge. We propose the deformable anatomy-aware registration toolkit (DART), a masked autoencoder (MAE)-based approach, to improve the keypoint-supervised registration of lung CTs. Our method incorporates features from multiple decoders of networks trained to segment anatomical structures, including the lung, ribs, vertebrae, lobes, vessels, and airways, to ensure that the MAE learns relevant features corresponding to the anatomy of the lung. The pretrained weights of the transformer encoder and patch embeddings are then used as the initialization for the training of downstream registration. We compare DART to existing state-of-the-art registration models. Our experiments show that DART outperforms the baseline models (Voxelmorph, ViT-V-Net, and MAE-TransRNet) in terms of target registration error of both corrField-generated keypoints with 17%, 13%, and 9% relative improvement, respectively, and bounding box centers of nodules with 27%, 10%, and 4% relative improvement, respectively. Our implementation is available at https://***/yunzhengzhu/DART.

关键词： Training Image registration Computed tomography Computational modeling Lung Brain modeling Transformers

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Contract-Inspired Contest Theory for Controllable Image Generation in Mobile Edge Metaverse

arXiv

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arXiv 2025年

作者： Liu, Guangyuan Du, Hongyang Wang, Jiacheng Niyato, Dusit Kim, Dong In College of Computing and Data Science The Energy Research Institute @ NTU Interdisciplinary Graduate Program Nanyang Technological University Singapore Department of Electrical and Electronic Engineering University of Hong Kong Hong Kong College of Computing and Data Science Nanyang Technological University Singapore Department of Electrical and Computer Engineering Sungkyunkwan University Korea Republic of

The rapid advancement of immersive technologies has propelled the development of the Metaverse, where the convergence of virtual and physical realities necessitates the generation of high-quality, photorealistic images to enhance user experience. However, generating these images, especially through Generative Diffusion Models (GDMs), in mobile edge computing environments presents significant challenges due to the limited computing resources of edge devices and the dynamic nature of wireless networks. This paper proposes a novel framework that integrates contract-inspired contest theory, Deep Reinforcement Learning (DRL), and GDMs to optimize image generation in these resource-constrained environments. The framework addresses the critical challenges of resource allocation and semantic data transmission quality by incentivizing edge devices to efficiently transmit high-quality semantic data, which is essential for creating realistic and immersive images. The use of contest and contract theory ensures that edge devices are motivated to allocate resources effectively, while DRL dynamically adjusts to network conditions, optimizing the overall image generation process. Experimental results demonstrate that the proposed approach not only improves the quality of generated images but also achieves superior convergence speed and stability compared to traditional methods. This makes the framework particularly effective for optimizing complex resource allocation tasks in mobile edge Metaverse applications, offering enhanced performance and efficiency in creating immersive virtual environments. © 2025, CC BY.

关键词： Mobile edge computing

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