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Mechanistic modeling of copper corrosions in data center environments

Building Simulation 2024年第3期17卷 483-492页

作者： Rui Zhang Jianshun Zhang Roger Schmidt Jeremy L.Gilbert Department of Mechanical and Aerospace Engineering College of Engineering and Computer ScienceSyracuse UniversitySyracuseNY13244USA Buildings and Transportation Science Division Oak Ridge National LaboratoryOak RidgeTN37830USA SyracuseCoE-New York Center of Excellence in Environmental and Energy Systems Syracuse University727 E.Washington StreetSyracuseNY13244USA Department of Bioengineering Clemson UniversityClemson-Medical University of South Carolina Bioengineering ProgramCharlestonSC29425USA

Air-side economizers are increasingly used to take advantage of“free-cooling”in data centers with the intent of reducing the carbon footprint of ***,they can introduce outdoor pollutants to indoor environment of data centers and cause corrosion damage to the information technology *** evaluate the reliability of information technology equipment under various thermal and air-pollution conditions,a mechanistic model based on multi-ion transport and chemical reactions was *** model was used to predict Cu corrosion caused by Cl_(2)-containing pollutant *** also accounted for the effects of temperature(25℃and 28℃),relative humidity(50%,75%,and 95%),and *** also identified higher air temperature as a corrosion barrier and higher relative humidity as a corrosion accelerator,which agreed well with the experimental *** average root mean square error of the prediction was 13.7Å.The model can be used to evaluate the thermal guideline for data centers design and operation when Cl_(2)is present based on pre-established acceptable risk of corrosion in data centers’environment.

关键词： chloride pollutant mixture copper corrosion model data center temperature relative humidity synergistic effect

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Camera-based Motion Correction for PET/MR Brain Imaging

Camera-based Motion Correction for PET/MR Brain Imaging

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2022 IEEE Nuclear science Symposium, Medical Imaging Conference, and Room Temperature Semiconductor Detector Conference, IEEE NSS MIC RTSD 2022

作者： Fisher, Jonathan Groll, Andrew Kim, Chris C. Innes, Derek Levin, Craig S. Stanford University Department of Electrical Engineering CA United States Molecular Imaging Program Stanford University Department of Radiology CA United States Stanford University Department of Computer Science CA United States Stanford University Physics Electrical Engineering and Bioengineering Department of Radiology CA United States

ISBN: (纸本)9781665488723

In this work, we evaluated the performance of a camera-based rigid body motion correction solution in PET studies. We compared the image quality obtained by reconstructing a static phantom scan to those obtained by reconstructing a moving phantom scan with and without applying motion correction. Our suggested solution uses a camera to track a 3D marker attached to the object to be imaged (in this work, a resolution phantom). This data was incorporated in the multiple acquisition frames (MAF) image reconstruction algorithm to compensate for motion. While we got multiple spatially shifted replicas of the resolution phantom in the motion study's reconstructed image when motion correction was not applied, the motion-corrected image was comparable to the static image, with some degradation in spatial resolution (3.2-4.2 vs. 2.8-3.2 mm) and lower peak to valley ratio (indicating lower contrast to noise ratio). The context of the results presented is in PET/MR imaging, but in principle, this motion compensation method could be used in any type of medical imaging modality. © 2022 IEEE.

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Human intracortical responses to varying electrical stimulation conditions are separable in low-dimensional subspaces

Human intracortical responses to varying electrical stimulat...

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2022 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2022

作者： Sun, Samantha Levinson, Lila H. Paschall, Courtnie J. Herron, Jeffrey Weaver, Kurt Hauptman, Jason Ko, Andrew Ojemann, Jeffrey Rao, Rajesh P. N. University of Washington Paul G. Allen School of Computer Science & Engineering Department of Bioengineering SeattleWA98195 United States University of Washington Graduate Program in Neuroscience Paul G. Allen School of Computer Science & Engineering SeattleWA98195 United States University of Washington Paul G. Allen School of Computer Science & Engineering Department of Neurological Surgery SeattleWA98195 United States University of Washington Paul G. Allen School of Computer Science & Engineering Department of Radiology SeattleWA98195 United States

ISBN: (数字)9781665452588

ISBN: (纸本)9781665452588

Electrical stimulation is a powerful tool for targeted neurorehabilitation, and recent work in adaptive stimulation where stimulation can be adjusted in real-time has shown promise in improving stimulation outcomes and reducing stimulation-induced side effects. Mapping the relationship between electrical stimulation input and neural activity response can help reveal their interactions and can give us tools to iterate and improve on our stimulation protocols. Here, we introduce methods for identifying low-dimensional subspaces of human intracortical responses to electrical stimulation in invasive electroencephalography. In epilepsy patients (n=4) undergoing clinical monitoring, we applied a stimulation protocol of varying amplitude and frequency in 5-second intervals to capture a range of responses to different stimulation conditions. We characterized these responses using time-frequency spectral power, applied baseline subtraction and outlier removal procedures, and performed principal component analysis across frequencies. We identified that intracortical responses to different stimulation conditions can be represented in a 3-dimensional subspace, accounting for more than 95% of the variance. Using support vector machine classification, we demonstrated separability of intracortical responses in different stimulation conditions across subjects, where this separability was contingent on applying baseline subtraction and outlier removal. Our results represent a first step towards building a predictive model of neural response from stimulation input, an important prerequisite for adaptive closed-loop stimulation for targeted neurorehabilitation. © 2022 IEEE.

关键词： Electroencephalography

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Deep-learning triage of 3D pathology data for improved disease detection while reducing pathologist workloads

Deep-learning triage of 3D pathology data for improved disea...

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Microscopy Histopathology and Analytics, Microscopy 2024 - Part of Optica Biophotonics Congress: Biomedical Optics

作者： Gao, Gan Wang, Fiona Brenes, David Song, Andrew H. Chow, Sarah S.L. Mahmood, Faisal Liu, Jonathan T.C. Department of Mechanical Engineering University of Washington SeattleWA98195 United States Department of Computer Science University of Washington SeattleWA98195 United States Department of Pathology Brigham and Women's Hospital Harvard Medical School BostonMA02115 United States Department of Pathology Massachusetts General Hospital Harvard Medical School BostonMA02114 United States Cancer Program Broad Institute of Harvard and MIT CambridgeMA02142 United States Data Science Program Dana-Farber Cancer Institute BostonMA02215 United States Department of Bioengineering University of Washington SeattleWA98195 United States Department of Laboratory Medicine & Pathology University of Washington School of Medicine SeattleWA98195 United States

3D pathology can potentially improve disease detection, but the datasets are too large to review. We're developing a deep-learning-based triage method to identify the highest-risk 2D sections within 3D pathology d... 详细信息

关键词： Adversarial machine learning

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Empirical influence functions to understand the logic of fine-tuning

arXiv

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arXiv 2024年

作者： Matelsky, Jordan K. Ungar, Lyle Kording, Konrad P. Department of Bioengineering University of Pennsylvania PhiladelphiaPA United States Research & Exploratory Development Department Johns Hopkins University Applied Physics Laboratory LaurelMD United States Department of Computer and Information Science University of Pennsylvania PhiladelphiaPA United States Department of Bioengineering Department of Neuroscience University of Pennsylvania PhiladelphiaPA United States CIFAR LMB Program Canada

Understanding the process of learning in neural networks is crucial for improving their performance and interpreting their behavior. This can be approximately understood by asking how a model's output is influenced when we fine-tune on a new training sample. There are desiderata for such influences, such as decreasing influence with semantic distance, sparseness, noise invariance, transitive causality, and logical consistency. Here we use the empirical influence measured using fine-tuning to demonstrate how individual training samples affect outputs. We show that these desiderata are violated for both for simple convolutional networks and for a modern LLM. We also illustrate how prompting can partially rescue this failure. Our paper presents an efficient and practical way of quantifying how well neural networks learn from fine-tuning stimuli. Our results suggest that popular models cannot generalize or perform logic in the way they appear to. © 2024, CC BY.

关键词： Sampling

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Opto2P-FCM: A MEMS Based Miniature Two-Photon Microscope with Patterned Optogenetic Stimulation

Opto2P-FCM: A MEMS Based Miniature Two-Photon Microscope wit...

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Microscopy Histopathology and Analytics, Microscopy 2024 - Part of Optica Biophotonics Congress: Biomedical Optics

作者： Futia, Gregory L. Zohrabi, Mo McCullough, Connor Teel, Alec de Souza, Fabio Simoes Oroke, Ryan Bright, Victor M. Restrepo, Diego Gopinath, Juliet T. Gibson, Emily A. Department of Bioengineering University of Colorado Anschutz Medical Campus AuroraCO80045 United States Department of Cell and Developmental Biology University of Colorado Anschutz Medical Campus AuroraCO80045 United States Department of Electrical Computer and Energy Engineering University of Colorado BoulderCO80309 United States Department of Mechanical Engineering University of Colorado BoulderCO80309 United States Department of Physics University of Colorado BoulderCO80309 United States Materials Science and Engineering Program University of Colorado BoulderCO80309 United States

Miniaturized microscopes for monitoring neural activity are an indispensable tool for neuroscience research. We present a novel MEMS based miniature microscope with patterned optogenetic stimulation capabilities enabl... 详细信息

ISBN: (纸本)9781957171340

关键词： Microscopes

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A large language model-assisted education tool to provide feedback on open-ended responses

arXiv

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arXiv 2023年

作者： Matelsky, Jordan K. Parodi, Felipe Liu, Tony Lange, Richard D. Kording, Konrad P. Department of Bioengineering University of Pennsylvania United States Research & Exploratory Development Department Johns Hopkins University Applied Physics Laboratory United States Department of Neuroscience University of Pennsylvania United States Department of Computer Science University of Pennsylvania United States Department of Computer Science Rochester Institute of Technology United States CIFAR LMB Program

Open-ended questions are a favored tool among instructors for assessing student understanding and encouraging critical exploration of course material. Providing feedback for such responses is a time-consuming task that can lead to overwhelmed instructors and decreased feedback quality. Many instructors resort to simpler question formats, like multiple-choice questions, which provide immediate feedback but at the expense of personalized and insightful comments. Here, we present a tool that uses large language models (LLMs), guided by instructor-defined criteria, to automate responses to open-ended questions. Our tool delivers rapid personalized feedback, enabling students to quickly test their knowledge and identify areas for improvement. We provide open-source reference implementations both as a web application and as a Jupyter Notebook widget that can be used with instructional coding or math notebooks. With instructor guidance, LLMs hold promise to enhance student learning outcomes and elevate instructional methodologies. © 2023, CC BY-NC-SA.

关键词： Students

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GranatumX:A Community-engaging, Modularized, and Flexible Webtool for Single-cell Data Analysis

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Genomics, Proteomics & Bioinformatics 2021年第3期19卷 452-460页

作者： David G.Garmire Xun Zhu Aravind Mantravadi Qianhui Huang Breck Yunits Yu Liu Thomas Wolfgruber Olivier Poirion Tianying Zhao Cédric Arisdakessian Stefan Stanojevic Lana X.Garmire Department of Electrical Engineering&Computer Science University of MichiganAnn ArborMI 48109USA Epidemiology Program University of Hawaii Cancer CenterHonoluluHI 96813USA Department of Biostatistics University of MichiganAnn ArborMI 48109USA Department of Computational Medicine and Bioinformatics University of MichiganAnn ArborMI 48105USA Molecular Biosciences and Bioengineering Graduate Program University of Hawaii at ManoaHonoluluHI 96822USA

We present GranatumX,a next-generation software environment for single-cell RNA sequencing(scRNA-seq)data *** is inspired by the interactive webtool *** enables biologists to access the latest scRNA-seq bioinformatics methods in a web-based graphical *** also offers software developers the opportunity to rapidly promote their own tools with others in customizable *** architecture of GranatumX allows for easy inclusion of plugin modules,named Gboxes,which wrap around bioinformatics tools written in various programming languages and on various *** can be run on the cloud or private servers and generate reproducible *** is a community-engaging,flexible,and evolving software ecosystem for scRNA-seq analysis,connecting developers with bench *** is freely accessible at http://***/granatumx/app.

关键词： Single-cell RNA sequencing Analysis Pipeline Webtool Module

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Fabric-substrated capacitive biopotential sensors enhanced by dielectric nanoparticles

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Nano Research 2021年第9期14卷 3248-3252页

作者： Xiangjun Chen Xiaoxiang Gao Akihiro Nomoto Keren Shi Muyang Lin Hongjie Hu Yue Gu Yangzhi Zhu Zhuohong Wu Xue Chen Xinyu Wang Baiyan Qi Sai Zhou Hong Ding Sheng Xu Materials Science and Engineering Program University of California San DiegoLa JollaCA 92093USA Department of NanoEngineering University of California San DiegoLa JollaCA 92093USA Department of Electrical and Computer Engineering University of California San DiegoLa JollaCA 92093USA Department of Bioengineering University of California San DiegoLa JollaCA 92093USA

Wearable biopotential sensing devices are essential to long-term and real-time monitoring of human ***-contact,capacitive sensing electrodes prevent potential skin iritations,and are thus beneficial for long-term *** capacitive electrodes are either connected to a separate control circuit via external wires or have limited sensing capacitances,which leads to low signal *** study demonstrates a stretchable capacitive sensing device with integrated electrodes and control electronics,with enhanced signal *** electrodes and the control electronics are fabricated on a common fabric substrate for breathability and strain-limiting *** stretchable electrodes are based on an island-bridge design with a stretchability as high as-100%,and an area ratio as high as-80%.By using a dielectric calcium copper titanate(CCTO)composite as the adhesive layer,the electrode capacitance can be increased,yielding an enhanced signal-to-noise ratio(SNR)in the acquired *** device offers a convenient and comfortable approach for long-term non-contact monitoring of biopotential signals.

关键词： capacitive sensing biopotential stretchable calcium copper titanate(CCTO) signal-to-noise ratio(SNR)

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Comprehensive Study on Cherenkov Radiation for Ultrafast PET Detectors, Considering Refractive Index and Wavelength

Comprehensive Study on Cherenkov Radiation for Ultrafast PET...

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IEEE Symposium on Nuclear science (NSS/MIC)

作者： H.S. Shim H. Kang J. Kim J.S. Lee Y. Jeong Interdisciplinary Program of Bioengineering Seoul National University Seoul Republic of Korea Integrated Major in Innovative Medical Science Seoul National University Seoul Republic of Korea Department of Electrical and Computer Engineering Seoul National University Seoul Republic of Korea

This study aims to investigate the characteristics of Cherenkov radiation with respect to wavelength and refractive index. Refractive index is a function of wavelength, and when it changes, not only does the gain of Cherenkov radiation increase, but also the photon loss in the medium increases. Therefore, we examine how photons of different wavelengths behave under changing refractive index conditions. We adjust the refractive index to maintain a constant emission angle of Cherenkov radiation based on the deceleration rate of electrons moving in the medium. When electrons generating Cherenkov radiation move a total of 200 μm, both long-wavelength and short-wavelength photons are emitted at the initial stage; however, only short-wavelength photons are emitted at the late stage. Although the shorter-wavelength photons arrive first among the photons that reach the detector, the longer-wavelength photons are detected more, forming a significant peak, which is due to the fact that the former experience more absorption-based photon loss in the medium than the latter.

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