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Multiday electrophysiological recordings from freely behaving primates

Multiday electrophysiological recordings from freely behavin...

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28th Annual International Conference of the IEEE engineering in Medicine and Biology Society, EMBS'06

作者： Gilja, Vikash Linderman, Michael D. Santhanam, Gopal Afshar, Afsheen Ryu, Stephen Meng, Teresa H. Shenoy, Krishna V. Department of Electrical Engineering Stanford University Stanford CA United States Department of Computer Science Stanford University Stanford CA United States School of Medicine Stanford University Stanford CA United States Department of Neurosurgery Stanford University Stanford CA United States Neurosciences Program Stanford University Stanford CA United States

ISBN: (纸本)1424400325

Continuous multiday broadband neural data provide a means for observing effects at fine timescales over long periods. In this paper we present analyses on such data sets to demonstrate neural correlates for physically active and inactive time periods, as defined by the response of a head-mounted accelerometer. During active periods, we found that 5-25 Hz local field potential (LFP) power was significantly reduced, firing rate variability increased, and firing rates have greater temporal correlation. Using a single threshold fit to LFP power, 93% of the 403 5 minute blocks tested were correctly classified as active or inactive (as labeled by thresholding each block's maximal accelerometer magnitude). These initial results motivate the use of such data sets for testing neural prosthetics systems and for finding the neural correlates of natural behaviors. © 2006 IEEE.

关键词： Electrophysiology

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Neural recording stability of chronic electrode arrays in freely behaving primates

Neural recording stability of chronic electrode arrays in fr...

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28th Annual International Conference of the IEEE engineering in Medicine and Biology Society, EMBS'06

作者： Linderman, Michael D. Gilja, Vikash Santhanam, Gopal Afshar, Afsheen Ryu, Stephen Meng, Teresa H. Shenoy, Krishna V. Department of Electrical Engineering Stanford University Stanford CA United States Department of Computer Science Stanford University Stanford CA United States School of Medicine Stanford University Stanford CA United States Department of Neurosurgery Stanford University Stanford CA United States Neurosciences Program Stanford University Stanford CA United States

ISBN: (纸本)1424400325

Chronically implanted electrode arrays have enabled a broad range of advances, particularly in the field of neural prosthetics. Those successes motivate development of prototype implantable prosthetic processors for long duration, continuous use in freely behaving subjects. However, traditional experimental protocols have provided limited information regarding the stability of the electrode arrays and their neural recordings. In this paper we present preliminary results derived from long duration neural recordings in a freely behaving primate which show variations in action potential shape and RMS noise across a range of time scales. These preliminary results suggest that spike sorting algorithms can no longer assume stable neural signals and will need to transition to adaptive signal processing methodologies to maximize performance. ©2006 IEEE.

关键词： Prosthetics

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A biomimetic MEMS neurotransmitter detector

A biomimetic MEMS neurotransmitter detector

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10th International Conference on Miniaturized Systems for Chemistry and Life sciences, MicroTAS 2006

作者： Koev, Stephan T. Wu, Li-Qun Payne, Gregory F. Ghodssi, Reza Department of Electrical and Computer Engineering University of Maryland College Park MD 20742 United States Institute for Systems Research University of Maryland College Park MD 20742 United States University of Maryland Biotechnology Institute University of Maryland College Park MD 20742 United States Bioengineering Graduate Program University of Maryland College Park MD 20742 United States

We demonstrate, for the first time, micromechanical detection of the neurotransmitter dopamine and its discrimination from ascorbic acid. Microcantilever sensors were fabricated and coated with the polysaccharide chitosan by electrodeposition. The cantilevers were used for electrochemical oxidation of dopamine solution. The products of this reaction crosslink the chitosan film and create a tensile stress, bending the cantilever out of plane considerably. By contrast, electrochemical oxidation of ascorbic acid solution does not cause chitosan crosslinking and appreciable cantilever bending. This method is an improvement over conventional electrochemical dopamine detection techniques (e.g. cyclic voltammetry) that are highly non-specific. © 2006 Society for Chemistry and Micro-Nano Systems.

关键词： Chitosan

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Where the girls are: Applying an integrated marketing approach to attract girls into engineering programs

Where the girls are: Applying an integrated marketing approa...

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113th Annual ASEE Conference and Exposition, 2006

作者： Pyke, Pat Aburusa-Lete, Leandra Budinoff, Christa Hampikian, Janet Luque, Michael Schrader, Cheryl Taylor, Michelle Boise State University United States College of Engineering Boise State University United States Visioneering LLC NASA Goddard Space Flight Center United States Academic Affairs Boise State University United States Materials Science and Engineering Department Boise School District United States Boise Science and Technology Girls Program United States College of Engineering Department of Electrical and Computer Engineering Boise State University United States Micron Technology Inc. United States

The steady national decline in women engineering students persists despite a plethora of programs and camps at engineering colleges around the country aimed at attracting girls into engineering and technical fields.1Discussions about this decline often suggest that influential cultural, media and marketing images may affect girls' career choices in ways that steer girls in directions other than engineering. When planning the first-ever overnight engineering camp for high school girls hosted at Boise State University, the planning team decided to embrace marketing methods to create realistic images about engineering that are relevant to the lives of girls. The planning team represented a partnership among Micron Technology, the southwest Idaho Society of Women Engineers section, Boise public school staff, and Boise State University faculty, staff and graduate students. The team defined four messages that formed the foundation for curriculum development and communications with prospective participants: 1) Engineers help the world;2) Engineers think creatively;3) Engineers enjoy working with other people;and 4) Engineers earn a good living. Demand for the "e-Girls" camp far exceeded expectations, and student evaluations at the end of the program indicated success at affecting the girls' understanding, perceptions and interest about engineering careers. The program will continue in 2006. © American Society for engineering Education, 2006.

关键词： Marketing

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Custom error control schemes for energy efficient bluetooth sensor networks

Custom error control schemes for energy efficient bluetooth ...

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International Symposium on Telecommunications

作者： Joao H. Kleinschmidt Walter C. Borelli Marcelo E. Pellenz Department of Telematics School of Electrical and Computer Engineering State University of Campinas Sao Paulo Brazil Graduate Program in Computer Science Pontifical Catholic University of Paraná Curitiba Parana Brazil

This paper analyzes the effect of custom error control schemes on the energy efficiency in Bluetooth sensor networks. The energy efficiency metric considers in just one parameter the energy and reliability constraints of the wireless sensor networks. New packet types are introduced using some error control strategies in the AUX1 packet, such as Hamming and BCH codes, with and without CRC for error detection. Two adaptive techniques are proposed that change the error control strategy based on the number of hops traversed by a packet through the network. The performance results are obtained through simulations in a channel with Rayleigh fading for networks with different number of hops, showing that error control can improve the energy efficiency of a Bluetooth-based sensor network.

关键词： Error correction Energy efficiency Bluetooth Wireless sensor networks Media Access Protocol Energy consumption Sensor phenomena and characterization Automatic repeat request Analytical models Cyclic redundancy check

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Best practices for promoting diversity in graduate engineering education

Best practices for promoting diversity in graduate engineeri...

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113th Annual ASEE Conference and Exposition, 2006

作者： Davis, Isadore DeLoatch, Eugene Kerns, Sherra Morell, Lueny Purdy, Carla Smith, Paige Truesdale, Samuel Rolls-Royce Morgan State University United States Morgan State College of Engineering United States Franklin W. Olin College of Engineering United States ASEE Hewlett-Packard United States Hewlett Packard Latin America University Relations Program United States Department of Chemical Engineering University of Puerto Rico Mayaguez Puerto Rico University of Cincinnati United States Department of Electrical and Computer Engineering and Computer Science University of Cincinnati United States University of Maryland College Park United States Engineering Program James A. Clark School of Engineering University of Maryland United States Employee Development Strategic Engineering Business Improvement Engineering Education Council Rolls-Royce Corporation United States

This presentation builds on panel discussions that began at the ASEE 2004 National Conference and continued at the 2005 Conference. Our focus is on promoting diversity in engineering education, with an emphasis on graduate education. This paper serves as a summary and introduction to this session, which is co-sponsored by three ASEE divisions-the Graduate Division, Women in engineering Division, and Minorities in engineering Division. In previous years, we presented evidence of the need for diversity in engineering education to promote the national good. We discussed specific issues of concern for promoting diversity in graduate engineering education. We outlined an overall strategy for achieving diversity in engineering education in general and in graduate engineering education in particular, based on a holistic model applicable to both education and industry. Now our goal is to identify best practices which can help to implement this strategy and to disseminate these practices to a broad audience. © American Society for engineering Education, 2006.

关键词： engineering education

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Cellular sorting with femtoliter fluid displacement for integrated flow cytometry systems

Cellular sorting with femtoliter fluid displacement for inte...

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Conference on Lasers and Electro-Optics (CLEO)

作者： Nicole B. Justis Victor Lien Randy Chen Yu-Hwa Lo Department of Materials Science and Engineering University of California San Diego La Jolla CA USA Department of Electrical and Computer Engineering University of California San Diego La Jolla CA USA Department of Bioengineering University of California San Diego San Diego CA USA

An acousto-optical microfluidic flow cytometer featuring femtoliter fluid-displacement was demonstrated with cellular sorting efficiencies at upwards of 99% at 5 kHz frequency actuation. Simulation and validation was ... 详细信息

ISBN: (纸本)1557528136

关键词： Microfluidics Ultrafast optics Computational modeling Atmospheric modeling Optical sensors Optical pulses Biomedical optical imaging

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Time-Frequency Analysis of Endogenous Calf Skeletal Muscle Vibromyograms

Time-Frequency Analysis of Endogenous Calf Skeletal Muscle V...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： A.A. Goddard G. Madhavan J.P. Cole M.L. Fowler K.J. McLeod Clinical Science and Engineering Research Center Department of BioengineeringInnovative Technologies ComplexThomas J. Watson School of Engineering and Applied Science State University of New York Binghamton NY USA Department of Electrical and Computer Engineering Thomas J. Watson School of Engineering and Applied Science State University of New York Binghamton NY USA

Calf skeletal muscle pump activity is essential for maintaining adequate venous and interstitial fluid flows in the dependent body. Correspondingly, failure of this extracorporeal pump leads to a host of acute and chronic physiological complications. The focus of this study is to assess the calf muscle pump contractility, more specifically through analysis of soleus muscle firing dynamics, in supine and seated positions, utilizing vibromyography (VMG). We have extended our previous investigations which relied on Fourier analysis of VMG recordings by utilizing wavelet-based time-frequency analysis to characterize the intrinsically non-stationary peripheral postural muscle dynamics during quiet sitting. Our objective was to identify the fibers types responsible for muscle pump activity during sitting, by looking for significant increases in activity in specific muscle fiber groups when a subject assumes an upright position from recumbency, and examine their temporal dynamics

关键词： Time frequency analysis Muscles Pumps Blood Heart Fluid flow Humans Extremities Fluid dynamics Wavelet analysis

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A Supervised Constructive Neuro-Immune Network for Pattern Classification

A Supervised Constructive Neuro-Immune Network for Pattern C...

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International Joint Conference on Neural Networks (IJCNN)

作者： H. Knidel L. Nunes de Castro F.J. Von Zuben Laboratory of Bioinformatics and Bioinspired Computing-LBiC Department of Computer Engineering and Industrial Automation-DCA School of Electrical and Computer Engineering-FEEC State University of Campinas-UNICAMP Sao Paulo Brazil Graduate Program in Computer Science Catholic University of Santos Sao Paulo Brazil

This paper proposes a supervised version of a learning algorithm for a constructive neuro-immune network. The proposed methodology is developed by taking ideas from the immune system and learning vector quantization. The resulting classification algorithm is characterized by high-performance, similar to the ones produced by alternative methods in the literature, and parsimonious solutions, with a much smaller set of prototypes per class when compared with the other approaches. The number of prototypes is automatically defined by the convergence criterion. The algorithm requires a single user-defined parameter for training, associated with the convergence criterion, and the computational cost is sufficiently reduced to support applications involving large data sets.

关键词： Pattern classification Immune system Neurons Supervised learning Vector quantization Classification algorithms Prototypes Clustering algorithms Unsupervised learning Artificial neural networks

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Diamond Ultramicroelectrode Chemical Sensing Arrays

Diamond Ultramicroelectrode Chemical Sensing Arrays

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IEEE SENSORS

作者： W.P. Kang J.L. Davidson K.L. Soh Y.M. Wong D.E. Cliffel A.B. Bonds Department of Electrical and Computer Engineering Vanderbilt University Nashville TN USA Interdisciplinary Program in Materials Science Vanderbilt University Nashville TN USA Department of Chemistry Vanderbilt University Nashville TN USA

Diamond ultramicroelectrode arrays (D-UMEAs) have been fabricated and evaluated experimentally for chemical sensing. D-UMEAs were found to demonstrate higher current density per unit active area than planar diamond macroelectrode and glassy carbon electrode. D-UMEAs could address new operating envelopes in electrochemical detection, and provide stable sensor electrodes for bio and extreme environments.

关键词： Sensor arrays USA Councils Fabrication Microelectrodes Chemical sensors Envelope detectors Chemical and biological sensors Biosensors Biomedical electrodes Powders

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