检索结果-内蒙古大学图书馆

Hazard Assessment of Permethrin, Copper Hydroxide, Acephate and Validamycin Nanopesticides on the Physiology of Drosophila: Novel Insights into the Cellular Internalization and Biological Effects

SSRN

引用

SSRN 2022年

作者： Demir, Eşref Kansız, Seyithan Doğan, Mehmet Topel, Önder Akkoyunlu, Gökhan Kandur, Muhammed Yusuf Demir, Fatma Turna Antalya Bilim University Vocational School of Health Services Department of Medical Services and Techniques Medical Laboratory Techniques Program Dosemealti Antalya07190 Turkey Akdeniz University Faculty of Science Department of Chemistry Antalya07070 Turkey Ankara University Faculty of Science Department of Chemistry Ankara07100 Turkey Akdeniz University Faculty of Medicine Department of Histology and Embryology Antalya07070 Turkey Department of Histology and Embryology Faculty of Medicine Kırklareli University Kırklareli Turkey Marmara University Faculty of Engineering Department of Bioengineering Industrial Biotechnology and Systems Biology Research Group İstanbul Turkey

New insights into the interaction between nanopesticides and edible plants are required to elucidate their impact on human health and agriculture. Nanopesticides include formulations consisting of organic/inorganic nanoparticles. Drosophila melanogaster has become a powerful model in genetic research thanks to its genetic similarity to mammals. This project mainly aimed to generate new evidence for toxic/genotoxic properties of different nanopesticides [nanoemulsion (permethrin nanopesticides, 20±5 nm), an inorganic nanoparticle as active ingredient [copper (II) hydroxide;Cu(OH)2 nanopesticides, 15±6 nm], polymer-based nanopesticide (acephate nanopesticides, 55±25 nm) and an inorganic nanoparticle associated with an organic active ingredient (validamycin nanopesticides, 1177±220 nm)] and their microparticulate forms (permethrin, copper (II) sulfate pentahydrate;CuSO4.5H2O, acephate and validamycin) widely used against agricultural pests, also showing merits of using Drosophila, a non-target in vivo eukaryotic model organism in nanogenotoxicology studies. Significant biological effects were noted at the highest doses of permethrin (0.06 and 0.1 mM), permethrin nanopesticides (1 and 2.5 mM), CuSO4.5H2O (1 and 5 mM), acephate and acephate nanopesticides (1 and 5 mM), validamycin and validamycin nanopesticides (1 and 2.5 mM). The results demonstrating the toxic/genotoxic potential of these nanopesticides through their impact on cellular internalization and gene expression will make significant contributions to future nanogenotoxicology studies. © 2022, The Authors. All rights reserved.

关键词： Risk assessment

来源：评论

学校读者我要写书评

暂无评论

Perovskite superlattices with efficient carrier dynamics

Research Square

引用

Research Square 2021年

作者： Xu, Sheng Lei, Yusheng Li, Yuheng Lu, Chengchangfeng Yan, Qizhang Gong, Huaxin Zhang, Song Zhou, Jiayun Zhang, Ruiqi Chen, Yimu Tsai, Hsinhan Gu, Yue Hu, Hongjie Lo, Yu-Hwa Nie, Wanyi Lee, Taeyoon Luo, Jian Yang, Kesong Jang, Kyung-In Department of Nanoengineering University of California San Diego La Jolla CA92093-0448 United States Department of Chemical Engineering Stanford University StanfordCA94305 United States Department of Electrical and Computer Engineering University of California San Diego La Jolla CA92093 United States Material Science and Engineering Program University of California San Diego La Jolla CA92093-0418 United States Los Alamos National Laboratory Los AlamosNM87545 United States School of Electrical and Electronic Engineering Yonsei University Seoul03722 Korea Republic of Department of Bio and Brain Engineering Korea Institute of Science and Technology Korea Republic of Department of Robotics Engineering Daegu Gyeongbuk Institute of Science and Technology Daegu42988 Korea Republic of Department of Bioengineering University of California San Diego La Jolla CA92093-0412 United States

Compared with their three-dimensional counterparts, low-dimensional metal halide perovskites with periodic inorganic/organic structures have shown promising stability and hysteresis-free electrical performance, which paves the way for next-generation optoelectronic devices. However, when integrated in devices, they have relatively limited efficiencies because devices usually require carrier transport through the film thickness direction. In conventionally grown single crystals, the carrier transport in the thickness direction is hindered by the insulating organic spacers. In addition, the strong quantum confinement from the organic spacers limits the generation and transport of free carriers. The carrier dynamics is further compromised by the presence of grain boundaries in polycrystals. Here, we report a low-dimensional metal halide perovskite superlattice with efficient carrier transport in three dimensions by epitaxial growth. Epitaxy on a slightly lattice-mismatched substrate compresses the organic spacers in the superlattice, which weakens the quantum confinement and further improves carrier dynamics. The performance of a low-dimensional perovskite superlattice solar cell has been certified under the quasi-steady state for the first time. Moreover, the device shows an unusually high open-circuit voltage, due to a unique intra-band exciton relaxation mechanism. © 2021, CC BY.

关键词： Grain boundaries

来源：评论

学校读者我要写书评

暂无评论

Author Correction: Dynamical flexible inference of nonlinear latent factors and structures in neural population activity

引用

Nature biomedical engineering 2025年第2期9卷 283页

作者： Hamidreza Abbaspourazad Eray Erturk Bijan Pesaran Maryam M Shanechi Ming Hsieh Department of Electrical and Computer Engineering Viterbi School of Engineering University of Southern California Los Angeles CA USA. Departments of Neurosurgery Neuroscience and Bioengineering University of Pennsylvania Philadelphia PA USA. Ming Hsieh Department of Electrical and Computer Engineering Viterbi School of Engineering University of Southern California Los Angeles CA USA. shanechi@usc.edu. Thomas Lord Department of Computer Science Alfred E. Mann Department of Biomedical Engineering Neuroscience Graduate Program University of Southern California Los Angeles CA USA. shanechi@usc.edu.

来源：评论

学校读者我要写书评

暂无评论

Microspheres for 3D bioprinting: a review of fabrication methods and applications

引用

Frontiers in bioengineering and biotechnology 2025年 13卷 1551199页

作者： Dmitri Karaman Kira Williams Jolene Phelps Fynn La Boucan Gretchen Lewandowski Kerrin O'Grady Bosco Yu Stephanie M Willerth Department of Mechanical Engineering University of Victoria Victoria BC Canada. Division of Medical Sciences University of Victoria Victoria BC Canada. Axolotl Biosciences Victoria BC Canada. Biomedical Engineering Program Department of Mechanical Engineering University of Victoria Victoria BC Canada. Biology Program Department of Science University of Victoria Victoria BC Canada. Department of Biomedical and Chemical Engineering Syracuse University Syracuse NY United States. BioInspired Syracuse Institute for Material and Living Systems Syracuse University Syracuse NY United States. School of Biomedical Engineering Faculty of Applied Science and Faculty of Medicine University of British Columbia Vancouver BC Canada.

Bioprinting incorporates printable biomaterials into 3D printing to create intricate tissues that maintain a defined 3D structure while supporting the survival and function of relevant cell types. A major challenge in 3D bioprinting is tuning material properties to ensure compatibility with different types of cells, while accurately mimicking the physiological microenvironment. Developing novel bioinks tailored to specific applications can help address this challenge by combining various materials and additives to tune the bioink formulation. Microspheres - small spherical particles - can incorporate drugs or growth factors to enable their controlled release, encapsulate cells to provide protection during printing, and provide structural reinforcement to tune mechanical properties and enable complex architectures. The particles range in size from 1 to 1000 μm and can be tuned to meet desired functions by optimizing their mode of production and the materials used for fabrication. This review presents an overview of microsphere production methods and considerations for optimizing the production process. It then summarizes how microspheres have been used to date in bioprinting applications. Finally, the existing challenges associated with the creation and use of microspheres are discussed along with avenues for future research.

关键词： biomaterials bioprinting drug encapsulation electrospray emulsification microfluidics microspheres

来源：评论

学校读者我要写书评

暂无评论

Radio-pathomic estimates of cellular growth kinetics predict survival in recurrent glioblastoma

引用

CNS Oncology 2024年第1期13卷 2415285页

作者： Oshima, Sonoko Yao, Jingwen Bobholz, Samuel Nagaraj, Raksha Raymond, Catalina Teraishi, Ashley Guenther, Anna-Marie Kim, Asher Sanvito, Francesco Cho, Nicholas S C Eldred, Blaine S Connelly, Jennifer M Nghiemphu, Phioanh L Lai, Albert Salamon, Noriko Cloughesy, Timothy F LaViolette, Peter S Ellingson, Benjamin M UCLA Brain Tumor Imaging Laboratory (BTIL) Center for Computer Vision & Imaging Biomarkers University of California Los Angeles Los Angeles 90024 CA United States Department of Radiological Sciences David Geffen School of Medicine University of California Los Angeles Los Angeles 90024 CA United States Department of Bioengineering Henry Samueli School of Engineering & Applied Science University of California Los Angeles Los Angeles 90024 CA United States Department of Radiology Medical College of Wisconsin Milwaukee 53226 WI United States Medical Scientist Training Program David Geffen School of Medicine University of California Los Angeles Los Angeles 90024 CA United States UCLA Neuro-Oncology Program David Geffen School of Medicine University of California Los Angeles Los Angeles 90024 CA United States Department of Neurology Medical College of Wisconsin Milwaukee 53226 WI United States Department of Neurology David Geffen School of Medicine University of California Los Angeles Los Angeles 90024 CA United States Department of Biophysics Medical College of Wisconsin Milwaukee 53226 WI United States Department of Biomedical Engineering Medical College of Wisconsin Milwaukee 53226 WI United States Department of Psychiatry & Biobehavioral Sciences David Geffen School of Medicine University of California Los Angeles Los Angeles 90024 CA United States Department of Neurosurgery David Geffen School of Medicine University of California Los Angeles Los Angeles 90024 CA United States

Aim: A radio-pathomic machine learning (ML) model has been developed to estimate tumor cell density, cytoplasm density (Cyt) and extracellular fluid density (ECF) from multimodal MR images and autopsy pathology. In this multicenter study, we implemented this model to test its ability to predict survival in patients with recurrent glioblastoma (rGBM) treated with chemotherapy. Methods: Pre- and post-contrast T₁-weighted, FLAIR and ADC images were used to generate radio-pathomic maps for 51 patients with longitudinal pre- and post-treatment scans. Univariate and multivariate Cox regression analyses were used to test the influence of contrast-enhancing tumor volume, total cellularity, mean Cyt and mean ECF at baseline, immediately post-treatment and the pre- and post-treatment rate of change in volume and cellularity on overall survival (OS). Results: Smaller Cyt and larger ECF after treatment were significant predictors of OS, independent of tumor volume and other clinical prognostic factors (HR = 3.23 × 10^-6, p < 0.001 and HR = 2.39 × 10⁵, p < 0.001, respectively). Both post-treatment volumetric growth rate and the rate of change in cellularity were significantly correlated with OS (HR = 1.17, p = 0.003 and HR = 1.14, p = 0.01, respectively). Conclusion: Changes in histological characteristics estimated from a radio-pathomic ML model are a promising tool for evaluating treatment response and predicting outcome in rGBM. © 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

关键词： MRI rad-path radiopathomic mapping recurrent glioblastoma survival tumor growth rate

来源：评论

学校读者我要写书评

暂无评论

Isothermal Crystallization Kinetics of Nylon 10T and Nylon 10T/1010 Copolymers:Effect of Sebacic Acid as a Third Comonomer

引用

Journal of Wuhan University of Technology(materials science) 2018年第5期33卷 1247-1255页

作者： WANG Zhongqiang HU Guosheng ZHANG Jingting XU Jiusheng SHI Wenbo Institute of Maeromolecules and Bioengineering School o/Materials Science and EngineeringNorth University of ChinaTaiyuan 030051China Guangdong Sinoplast Advanced Material Co.Ltd. Dongguan 523860China

Nylon 10T and nylon 10T/1010 samples were synthesized by direct melt *** isothermal crystallization kinetics of nylon 10T and nylon 10T/1010 was investigated by means of differential scanning calorimetry（DSC）.The crystallization kinetics under isothermal condition has been analyzed by the Avrami *** was found that the Avrami equation was well-suited to describe the isothermal crystallization kinetics,combined with the results of the Turnbull-Fisher *** values of Tm^0 and Kg were obtained by Hoffman-Weeks and Lauritzen-Hoffman equations,*** activation energies for isothermal crystallization of nylon 10T and nylon 10T/1010 were determined using the Arrhenius equation and found to be-123.24 and-81.86 kJ·mol^（-1）,respectively,which reveals that the crystallization ability of nylon 10T/1010was lower than that of nylon 10T during the isothermal crystallization *** crystal morphology was observed by means of polarized optical microscopy（POM）and X-ray diffraction（XRD）.It was found that the addition of sebacic acid comonomer did not change the crystal form of nylon 10T,but significantly increased the number and decreased the size of spherulites.

关键词： melt polymerization nylon 10T nylon 10T/1010 semiaromatic polyamides crystallization kinetics isothermal crystallization

来源：评论

学校读者我要写书评

暂无评论

Quantitative contributions of solution atoms, precipitates and deformation to microstructures and properties of Al-Sc-Zr alloys

引用

Transactions of Nonferrous Metals Society of China 2019年第5期29卷 907-918页

作者： Ren-guo GUAN Hong-mei JIN Wensen JIANG Xiang WANG Yu-xiang WANG Zheng LI Jian ZHANG Huinan LIU Center of Advanced Lubrication and Seal Materials State Key Laboratory of Solidification ProcessingNorthwestern Polytechnical UniversityXi’an 710072China School of Material Science and Engineering Northeastern UniversityShenyang 110819China Materials Science and Engineering Program University of California at Riverside900 University AvenueRiversideCalifornia 92521USA Department of Bioengineering University of California at Riverside900 University AvenueRiversideCalifornia 92521USA

In order to investigate the effects of solid solution atoms, precipitated particles and cold deformation on the microstructures and properties of Al-Sc-Zr alloys, the Al-Sc-Zr alloys prepared by continuous rheo-extrusion were treated by thermomechanical treatment, analyzed for conductivity and mechanical properties by tensile and microhardness testing, and characterized using optical microscope, TEM and STEM. A mathematical model was established to quantitatively characterize the contribution of solid solution atoms, precipitates and cold deformation to the conductivity of the alloy. The results show that the strength of Al alloy can be significantly improved by solid solution, aging and cold deformation, and the quantitative impacts of solution atoms, precipitates and cold deformation on the conductivity of Al alloy are 10.5%(IACS), 2.3%(IACS) and 0.5%(IACS), respectively. Aging and cold deformation treatments are the keys to obtain high-strength and high-conductivity aluminum alloy wires.

关键词： Al.Sc.Zr alloy thermal treatment cold deformation mechanical properties conductivity

来源：评论

学校读者我要写书评

暂无评论

Coating of polydimethylsiloxane nanoparticles improves bioactivity of cellulose paper for culture of fibroblasts

引用

International Journal of Biological Macromolecules 2025年第Pt 4期311卷 143975页

作者： Maparu, Auhin Kumar Singh, Prerana Rai, Beena Sharma, Ashutosh Sivakumar, Sri Physical Sciences Research Area TCS Research Tata Research Development and Design Centre Tata Consultancy Services 54-B Hadapsar Industrial Estate Maharashtra Pune411013 India Department of Chemical Engineering Indian Institute of Technology Kanpur Uttar Pradesh208016 India Department of Biological Sciences and Bioengineering Indian Institute of Technology Kanpur Uttar Pradesh208016 India Material Science Programme Thematic Unit of Excellence on Soft Nanofabrication Centre for Environmental Science & Engineering Mehta Family Centre for Engineering in Medicine Gangwal School of Medical Sciences and Technology Indian Institute of Technology Kanpur Uttar Pradesh208016 India

Paper has recently emerged as a promising platform for cell culture owing to its flexible three-dimensional matrix, high porosity, biocompatibility, cost-effectiveness and widespread availability. However, native paper is devoid of cell adhesion motifs and various surface modification techniques are generally employed on paper substrate before cell seeding, most of which are complicated, expensive, time-consuming and require use of sophisticated instruments. In the present work, for the first time, we have coated polydimethylsiloxane (PDMS) nanoparticles (NPs) onto the cellulose fibers of paper to improve its bioactivity while retaining the fibrous morphology. A modified nanoprecipitation method was employed to prepare PDMS NPs of ~30 nm size and 1 mg/ml concentration. Owing to the inherent skin-like mechanical properties of PDMS, the NPs could offer anchoring sites to the skin cells in the form of nanotopographic and biomechanical cues for enhanced interaction with the paper matrix. NIH/3T3 fibroblast cells cultured on the coated paper substrate exhibited elongated and spindle like morphology (characteristic of fibroblasts in vivo) with an increase in cellular adhesion and proliferation (ca. 74 % more cell viability after 48 h as compared to uncoated paper). After culturing for 15 days, the fibroblasts secreted excessive collagen and formed tissue-like sheet of cells which further advocate for the excellent suitability of the PDMS NPs coated paper substrate for culture of skin cells. © 2025 Elsevier B.V.

关键词： Tissue culture

来源：评论

学校读者我要写书评

暂无评论

Erratum to: materials and devices for flexible and stretchable photodetectors and light-emitting diodes

引用

Nano Research 2021年第11期14卷 4362-4362页

作者： Jun-Kyul Song Min Sung Kim Seungwon Yoo Ja Hoon Koo Dae-Hyeong Kim Center for Nanoparticle Research Institute for Basic Science(IBS)Seoul08826Republic of Korea School of Chemical and Biological Engineering and Institute of Chemical Processes Seoul National UniversitySeoul08826Republic of Korea Interdisciplinary Program for Bioengineering Seoul National UniversitySeoul08826Republic of Korea Department of Materials Science and Engineering Seoul National UniversitySeoul08826Republic of Korea

Erratum to Nano Research 2021,14(9):2919-2937 https://***/10.1007/s 12274-021-3447-3 The figure caption of Figure 1,instead of Figure 1 Schematic illustration of various nanomaterials and organic materials used in fle... 详细信息

关键词： diodes emitting Figure

来源：评论

学校读者我要写书评

暂无评论

Microscopic picture of paraelectric perovskites from structural prototypes

引用

Physical Review Research 2022年第1期4卷 L012042-L012042页

作者： Michele Kotiuga Samed Halilov Boris Kozinsky Marco Fornari Nicola Marzari Giovanni Pizzi Theory and Simulation of Materials (THEOS) National Centre for Computational Design and Discovery of Novel Materials (MARVEL) École Polytechnique Fédérale de Lausanne CH-1015 Lausanne Switzerland Designed Material Technologies LLC P.O. Box 14548 Richmond Virginia 23221-9998 USA John A. Paulson School of Engineering and Applied Sciences Harvard University 29 Oxford Street Cambridge Massachusetts 02138 USA Robert Bosch LLC Research and Technology Center Cambridge Massachusetts 02139 USA Department of Physics and Science of Advanced Materials Program Central Michigan University Mt. Pleasant Michigan 48859 USA

We highlight with first-principles molecular dynamics the persistence of intrinsic 〈111〉 Ti off-centerings for BaTiO3 in its cubic paraelectric phase. Intriguingly, these are inconsistent with the Pm3¯m space group often used to atomistically model this phase using density-functional theory or similar methods. Therefore, we deploy a systematic symmetry analysis to construct representative structural models in the form of supercells that satisfy a desired point symmetry but are built from the combination of lower-symmetry primitive cells. We define as structural prototypes the smallest of these that are both energetically and dynamically stable. Remarkably, two 40-atom prototypes can be identified for paraelectric BaTiO3; these are also common to many other ABO3 perovskites. These prototypes can offer structural models of paraelectric phases that can be used for the computational engineering of functional materials. Last, we show that the emergence of B-cation off-centerings and the primitive-cell phonon instabilities is controlled by the equilibrium volume, in turn, dictated by the filler A cation.

关键词： Crystal symmetry Ferroelectricity Structural order parameter Paraelectrics

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：