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Annual Northeast bioengineering Conference

作者： Antony Thomas Chi-mon Chen Shu Yang Xuanhong Chen Yaling Liu Bioengineering Program Lehigh University USA Material Science and Engineering University of Pennsylvania USA Material Science and Engineering Lehigh University USA Mechanical Engineering and Mechanics Lehigh University USA

This work aims to design, fabricate, and characterize a micro-patterned surface that will be integrated into microfluidic devices to enhance particle and rare cell capture efficiency. Capture of ultralow concentration of circulating tumor cells in a blood sample is of vital importance for early diagnostics of cancer diseases. Despite the significant progress achieved in development of cell capture techniques, the enhancement in capture efficiency is still limited and often accompanied with drawbacks such as low throughput, low selectivity, pre-diluting requirement, and cell viability issues. The goal of this work is to design a biomimetic surface that could significantly enhance particle/cell capture efficacy through computational modeling, surface patterning, and microfluidic integration and testing. A PDMS surface with microscale ripples is functionalized with epithelial cell adhesion molecule (EpCAM) antibody to capture prostate cancer PC3 cells. Our microfluidic chip with micropatterns has shown significantly higher cell capture efficiency and selectivity compared to the chips with plane surface or classical herringbone-grooves.

关键词： Surface waves Microfluidics Tumors Educational institutions USA Councils materials Testing

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In vitro cytotoxicity evaluation of four vital pulp therapy materials on l929 fibroblasts

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ISRN dentistry 2014年第1期2014卷 191068页

作者： Aniket S Wadajkar Chul Ahn Kytai T Nguyen Qiang Zhu Takashi Komabayashi Department of Bioengineering University of Texas at Arlington Arlington TX 76019 USA Joint Biomedical Engineering Program University of Texas at Arlington and University of Texas Southwestern Medical Center Dallas TX 75390 USA. Department of Clinical Sciences University of Texas Southwestern Medical Center Dallas TX 75390-9066 USA. Division of Endodontology University of Connecticut Health Center Farmington CT 06030-1715 USA. Department of Endodontics West Virginia University School of Dentistry One Medical Center Drive P.O. Box 9450 Health Science Center North Morgantown WV 26506-9450 USA.

The aim of this study was to evaluate cytotoxicity of direct pulp capping materials such as Dycal, Life, ProRoot MTA, and Super-Bond C&B on L929 fibroblasts. Freshly mixed or set materials were prepared and eluted by incubation with cell culture medium for working time period (fresh) or for 6 hours (set). The cells were exposed to media containing elutes for 24 hours, after which the cell survival was evaluated by MTS assays. In freshly mixed materials, average ± standard deviation % cell viabilities were 40.2 ± 14.0%, 43.7 ± 16.0%, 72.9 ± 12.7%, and 66.0 ± 13.6% for Dycal, Life, ProRoot MTA, and Super-Bond C&B, respectively. There was no statistical difference in cell viabilities among material groups, whereas in set materials, the cell viabilities were 48.7 ± 14.8%, 37.2 ± 10.6%, 46.7 ± 15.2%, and 100 ± 21.9% for Dycal, Life, ProRoot MTA, and Super-Bond C&B, respectively. Super-Bond C&B showed more cell viabilities than the other three material groups (P < 0.05). The four vital pulp therapy materials had similar cytotoxicity when the materials were fresh. Super-Bond C&B was less cytotoxic than Dycal, Life, and ProRoot MTA after the materials were set, which suggests the use of SB-C&B in future in vivo clinical investigations.

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Metal oxides as catalyst promoters for methanol oxidation

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2012 MRS Spring Meeting

作者： Kolla, Praveen Kerce, Kimberly Fong, Hao Smirnova, Alevtina Material Engineering Science Program South Dakota School of Mines and Technology Rapid City SD 57701 United States Department of Chemistry South Dakota School of Mines and Technology Rapid City SD 57701 United States

ISBN: (纸本)9781605114231

The Transition metal oxides such as TiO2 and CeO2 as catalyst and co-catalyst materials were studied for methanol oxidation. The metal oxide nanoparticles were impregnated into carbon aerogel and Pt-Ru/C (Tanaka) by modified sol-gel Pechini method and heat-treated at different temperatures. Crystal structure, particle size and composition of the catalyst particles were studied using XRD, TEM and EDS techniques. The electrochemical activity and stability of these catalyst materials were studied in acidic medium and the results were compared to their corresponding specific and active surface areas. The aerogel supported metal oxides were stable and proved for better methanol oxidation, while a significant synergetic effect in electro-oxidation is observed when the metal oxides were impregnated into the structure of Pt-Ru/C catalyst. The methanol-oxidation was further improved after heat treatment due to its improved structural and surface properties. © 2012 materials Research Society.

关键词： Electrooxidation

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Metal Oxides as Catalyst Promoters for Methanol Oxidation

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MRS Online Proceedings Library (OPL) 2012年第1期1446卷 mrss12-1446-u09-36-mrss12-1446-u09-36页

作者： Praveen Kolla Kimberly Kerce Hao Fong Alevtina Smirnova Material Engineering Science Program South Dakota School of Mines and Technology Rapid City SD 57701 U.S.A. Department of Chemistry South Dakota School of Mines and Technology Rapid City SD 57701 U.S.A. Material Engineering Science Program

关键词： aerogel catalytic nanostructure

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Preparation of submicron-sized hydroxyapatite powders by spray pyrolysis

Preparation of submicron-sized hydroxyapatite powders by spr...

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23rd Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2011

作者： Cho, Jung Sang Rhee, Sang-Hoon Interdisciplinary Program of Bioengineering College of Engineering Seoul National University Seoul 152-742 Korea Republic of Department of Dental Biomaterials Science School of Dentistry Seoul National University Seoul 110-749 Korea Republic of

ISBN: (纸本)9783037852552

Dense and submicron-sized hydroxyapatite powders were synthesized through spray pyrolysis of calcium phosphate solution with polyethylene glycol (PEG). Irregular shaped and fragile hydroxyapatite aggregates, and spherical and hollow hydroxyapatite particles were obtained after spray pyrolysis at 1100 °C when using calcium phosphate solution with and without PEG, respectively. After dewaxing at 650 °C for 3 hours, the hydroxyapatite aggregates were broken into submicron-sized particles whereas micron-sized spherical hollow particles were almost intact. The relative densities of hydroxyapatite disks made by submicron and micron sized hydroxyapatite particles were about 90% and 81%, respectively, after sintering at 1110 °C for 3 hours. The results were explained in terms of the disintegrating function of carbon which was previously formed among the hydroxyapatite aggregates by the decomposition of PEG during spray pyrolysis. © (2012) Trans Tech Publications.

关键词： Carbon

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Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015

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BMC genomics 2016年第6期17 Suppl 6卷 487页

作者： Jerry W. Shay Noriko Homma Ruyun Zhou Muhammad Imran Naseer Adeel G. Chaudhary Mohammed Al-Qahtani Nobutaka Hirokawa Maryam Goudarzi Albert J. Fornace Saleh Baeesa Deema Hussain Mohammed Bangash Fahad Alghamdi Hans-Juergen Schulten Angel Carracedo Ishaq Khan Hanadi Qashqari Nawal Madkhali Mohamad Saka Kulvinder S. Saini Awatif Jamal Jaudah Al-Maghrabi Adel Abuzenadah Adeel Chaudhary Mohammed Al Qahtani Ghazi Damanhouri Heba Alkhatabi Anne Goodeve Laura Crookes Nikolas Niksic Nicholas Beauchamp Adel M. Abuzenadah Jim Vaught Bruce Budowle Mourad Assidi Abdelbaset Buhmeida Leena Merdad Sudhir Kumar Sayaka Miura Karen Gomez Mahmood Rasool Ahmed Rebai Sajjad Karim Hend F. Nour Eldin Heba Abusamra Elham M. Alhathli Nada Salem Mohammed H. Al-Qahtani Hossam Faheem Ashok Agarwa Eberhard Nieschlag Joachim Wistuba Oliver S. Damm Mohd A. Beg Taha A. Abdel-Meguid Hisham A. Mosli Osama S. Bajouh Serdar Coskun Muhammad Abu-Elmagd Ashraf Dallol Sahar Hakamy Wejdan Al-Qahtani Asia Al-Harbi Shireen Hussain Burak Ozkosem Rick DuBois Safia S. Messaoudi Maryam T. Dandana Touhami Mahjoub Wassim Y. Almawi S. Abdalla M. Nabil Al-Aama Asmaa Elzawahry Tsuyoshi Takahashi Sachiyo Mimaki Eisaku Furukawa Rie Nakatsuka Isao Kurosaka Takahiko Nishigaki Hiromi Nakamura Satoshi Serada Tetsuji Naka Seiichi Hirota Tatsuhiro Shibata Katsuya Tsuchihara Toshirou Nishida Mamoru Kato Sajid Mehmood Naeem Mahmood Ashraf Awais Asif Muhammad Bilal Malik Siddique Mehmood Aadil Hussain Qazi Mohammad Sajid Jamal Mughees Uddin Siddiqui Mohammad A. Alzohairy Mohammad A. Al Karaawi Taoufik Nedjadi Heba Al-Khattabi Adel Al-Ammari Ahmed Al-Sayyad Hédia Zitouni Nozha Raguema Marwa Ben Ali Wided Malah Raja Lfalah Wassim Almawi Mohammed Elanbari Andrey Ptitsyn Sana Mahjoub Rabeb El Ghali Bechir Achour Nidhal Ben Amor Brahim N’siri Hamid Morjani Esam Azhar Vera Chayeb Maryam Dendena Hedia Zitouni Khedija Zouari-Limayem Bassem Refaat Ahmed M. Ashshi Sarah A. Batwa Hazem Ramadan Amal Awad Ahmed Ateya Adel Galal Ahmed El-Shemi Ahmad Ashshi Mohammed Basalamah Youjin Na Cha University of Texas Southwestern Medical Center Dallas USA Department of Cell Biology and Anatomy Graduate School of Medicine the University of Tokyo Tokyo Japan Center of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Department of Biochemistry and Molecular & Cellular Biology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Oncology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Radiation Medicine Lombardi Comprehensive Cancer Center Georgetown University Washington USA Center of Excellence in Genomic Medicine Research (CEGMR) King Abdulaziz University Jeddah Kingdom of Saudi Arabia King Fahd Medical Research Centre King Abdulaziz University Jeddah Saudi Arabia Centre of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Sheffield Diagnostic Genetic Service Sheffield Children’s NHS Foundation Trust Western Bank Sheffield UK Center of Innovations in Personalized Medicine King Abdulaziz University Jeddah Saudi Arabia President ISBER Editor-in-Chief Biopreservation & Biobanking ᅟ USA Institute of Applied Genetics Department of Molecular and Medical Genetics University of North Texas Health Science Center Fort Worth USA Department of Dental Public Health Faculty of Dentistry King Abdulaziz University Jeddah Saudi Arabia Institute for Genomics and Evolutionary Medicine Temple University Philadelphia USA Center of Excellence in Genomic Medicine King Abdulaziz University Jeddah Kingdom of Saudi Arabia Laboratory of Molecular and Cellular Screening Processes (Bioinformatics Group) Centre of Biotechnology of Sfax Sfax Tunisia Fujitsu Technology Solutions International ᅟ ᅟ Case Western Reserve University School of Medicine and Lerner College of Medicine Cleveland Clinic Foundation Cleveland USA American Center for Reproductive Medicine Andrology Center Cleveland USA Center for Reproductive Medicine and

O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabolomics in gut microbiome research Maryam Goudarzi, Albert J. Fornace Jr. O4 A unique integrated system to discern pathogenesis of central nervous system tumors Saleh Baeesa, Deema Hussain, Mohammed Bangash, Fahad Alghamdi, Hans-Juergen Schulten, Angel Carracedo, Ishaq Khan, Hanadi Qashqari, Nawal Madkhali, Mohamad Saka, Kulvinder S. Saini, Awatif Jamal, Jaudah Al-Maghrabi, Adel Abuzenadah, Adeel Chaudhary, Mohammed Al Qahtani, Ghazi Damanhouri O5 RPL27A is a target of miR-595 and deficiency contributes to ribosomal dysgenesis Heba Alkhatabi O6 Next generation DNA sequencing panels for haemostatic and platelet disorders and for Fanconi anaemia in routine diagnostic service Anne Goodeve, Laura Crookes, Nikolas Niksic, Nicholas Beauchamp O7 Targeted sequencing panels and their utilization in personalized medicine Adel M. Abuzenadah O8 International biobanking in the era of precision medicine Jim Vaught O9 Biobank and biodata for clinical and forensic applications Bruce Budowle, Mourad Assidi, Abdelbaset Buhmeida O10 Tissue microarray technique: a powerful adjunct tool for molecular profiling of solid tumors Jaudah Al-Maghrabi O11 The CEGMR biobanking unit: achievements, challenges and future plans Abdelbaset Buhmeida, Mourad Assidi, Leena Merdad O12 Phylomedicine of tumors Sudhir Kumar, Sayaka Miura, Karen Gomez O13 Clinical implementation of pharmacogenomics for colorectal cancer treatment Angel Carracedo, Mahmood Rasool O14 From association to causality: translation of GWAS findings for genomic me

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A Superior Low‐Cost Cathode for a Na‐Ion Battery†

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Angewandte Chemie 2013年第7期125卷

作者： Long Wang Yuhao Lu Jue Liu Maowen Xu Jinguang Cheng Dawei Zhang John B. Goodenough Material Science and Engineering Program and Texas Materials Institute The University of Texas at Austin Austin TX 78712 (USA) Chemistry Department State University of New York at Stony Brook Stony Brook NY 11794 (USA) School of Chemical Engineering Hefei University of Technology Hefei 230009 (P.R. China)

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Properties and preparation of porous carbon material supported with modified TiO2

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Procedia engineering 2012年 27卷 557-563页

作者： Chengbao Liu Zhigang Chen Zhi Miao Feng Chen Cheng Gu Minqi Huang Xiaobing Zhao Department of Chemistry and Bioengineering Suzhou University of Science and Technology Suzhou 215009 China Jiangsu Key Laboratory for Environment Functional Materials Suzhou University of Science and Technology Suzhou 215009 School of Materials Science and Engineering Jiangsu University Zhenjiang 212013 China State Key laboratory of Crystal Material (Shandong University) Jinan 250100 School of Materials Science and Engineering Changzhou University Changzhou 213164 China

Titania (P25-type) was used as photocatalytic matrix, and ceria was introduced to modify P25 by a deposit method in order to improve the photocatalytic property. Recombination of charge carriers have been restrained by the oxygen storage effect of rare earth elements. Modified P25 (CeO2/TiO2) has been proved to be more effective in photocatalytic application by fluorescence spectrum. Then CeO2/TiO2 was wrapped on the surface of expanded graphite-amorphous carbon (EGC) to form a new kind of carbon based composite- adsorption and photocatalytic integration material (CTO/EGC). With a large amount of micropores on the surface, the specific surface area could reach 963m2/g, and the composite has a benefit in little molecular organic pollutants adsorption. With a synergistic effect of adsorption and photocatalytic, 100 mL methyl orange with the concentration of 50 mg/L could be effectively decomposed by 100 mg CTO/EGC, up to 96% after 3 hours.

关键词： Titania Porous carbon based adsorption material Ceria Surface modification Adsorption and photocatalytic synergistic effect

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Biotemplate synthesis of porous titanium oxide fiber and study on its photocatalytic performance

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Procedia engineering 2012年 27卷 519-525页

作者： Feng Chen Zhigang Chen Chengbao Liu Wei Wang Cheng Gu Juanning Ma School of Materials Science and Engineering Jiangsu University Zhenjiang 212013 China Jiangsu Key Laboratory for Environment Functional Materials Suzhou University of Science and Technology Suzhou 215009 China Department of Chemistry and Bioengineering Suzhou University of Science and Technology Suzhou 215009 China State Key laboratory of Crystal Material (Shandong University) Jinan 250100

Medium speed filter paper is applied as biotemplates to synthesize biogenic-TiO2. Through one step infiltration process in titanium-chloride-ethanol solution, followed by washing with ethanol, white sheets was obtained after calcination. Unique bio-morphic film-anatase-titania with diameter of ca. 1-3 μm were synthesized and characterized by Field Emission Scanning Electron Microscope (FESEM), High Resolution Transmission Electron Microscopy (HRTEM), X-ray Diffraction Spectroscopy (XRD) and so forth. The results showed that the products were composed 2-6 nm piled pores stacked by polycrystalline nanoparticles with sizes about 10 nm which arranged on the surface of biomorphic titania. The specific area of the sample was 71 m2/g. While the concentration of helianthine solution is 20 mg/L, catalyst amount 0.1 g/L, the reaction had a higher decoloring rate following irradiation with a UV light source, the decoloring rate can reach over 100% after 150 min.

关键词： Titania Bio-template Porous fibre Photocatalysis

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Preparation of porous TiO2 using eggshell membrane as template and its photocatalytic activity

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Procedia engineering 2012年 27卷 512-518页

作者： Zhigang Chen Chengbao Liu Feng Chen Yu Cao Jingjing Fan Jing Zhou Department of Chemistry and Bioengineering Suzhou University of Science and Technology Suzhou 215009 China Jiangsu Key Laboratory for Environment Functional Materials Suzhou University of Science and Technology Suzhou 215009 China School of Materials Science and Engineering Jiangsu University Zhenjiang 212013 China State Key laboratory of Crystal Material (Shandong University) Jinan 250100

Eggshell membrane (ESM) has been employed as a natural biotemplate. Using tetrabutyl titanate as titanium resource and ethanol as solvent, through a two-step infiltration process based on the surface chemistry and biochemistry interactions involved in organic-inorganic interface, titanium ion evenly combined with biomembrane by controlling impregnant pH value. And then the hierarchical fibrous nano-porous anatase titanium dioxide was prepared after high temperature calcination. Unique bio-morphic microstructures with interwoven networks were synthesized and characterized by Field Emission Scanning Electron Microscope (FESEM), High Resolution Transmission Electron Microscopy (HRTEM), X-ray Diffraction Spectroscopy (XRD) and so forth. Titania was characterized by repetitious networks consisting of the porous hollow tubes with inner diameter of ca. 500 nm and thickness of about 300 nm. The tube wall was studded with piled pores which had 1∼5 nm aperture. While the concentration of phenol solution is 20 mg/L, catalyst amount 0.2 g/L, the reaction had a higher decoloring rate under an ultraviolet Hg lamp irradiation, the decoloring rate can reach over 90% after 120 min.

关键词： Titania Eggshell membrane Pores Photocatalysis phenol

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