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Current biology : CB 2025年第5期35卷 R173-R174页

作者： Maaike J Bierenbroodspot Tatyana Darienko Sophie de Vries Thomas Pröschold Iker Irisarri Jan de Vries University of Goettingen Institute for Microbiology and Genetics Department of Applied Bioinformatics Goettingen Germany. University of Goettingen Institute for Microbiology and Genetics Department of Applied Bioinformatics Goettingen Germany University of Goettingen Albrecht-von-Haller-Institute for Plant Sciences Department of Experimental Phycology and Culture Collection of Algae Goettingen Germany. Research Department for Limnology University of Innsbruck Mondsee Austria. Department of Biodiversity and Evolutionary Biology Museo Nacional de Ciencias Naturales Madrid Spain Campus Institute Data Science University of Goettingen Goettingen Germany. Electronic address: Iker.Irisarri@mncn.csic.es. Campus Institute Data Science University of Goettingen Goettingen Germany Goettingen Center for Molecular Biosciences (GZMB) Department of Applied Bioinformatics University of Goettingen Goettingen Germany. Electronic address: devries.jan@uni-goettingen.de.

The more we learn about the algal relatives of embryophytes (land plants), the more complex and fascinating the evolution of key streptophyte traits becomes. With the sequencing of the Klebsormidium nitens genome, a range of molecular traits shared with land plants were found - despite ca. 800 million years of divergence. A few years ago, Streptofilum was described, superficially resembling members of Klebsormidiophyceae but showing divergence in traits. In our recent study, we reconstructed a phylogenomic backbone for Klebsormidiophyceae, and Streptofilum was nested within, although we pointed out the difficulties in placing Streptofilum. Now, Žárský and Eliáš have commented on this placement, building on a different approach to analyze the data.

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Systematic Literature Review on Statistics and Machine Learning Predictive Models for Rice Phenotypes 8

Systematic Literature Review on Statistics and Machine Learn...

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8th International Conference on Computer science and Computational Intelligence, ICCSCI 2023

作者： Dominic, Nicholas Cenggoro, Tjeng Wawan Pardamean, Bens Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia Computer Science Department School of Computer Science Bina Nusantara University Jakarta11480 Indonesia Computer Science Department BINUS Graduate Program - Master of Computer Science Bina Nusantara University Jakarta11480 Indonesia

Predicting the best-quality of rice phenotypes is the priority among agricultural researchers to fulfill worldwide food security. Trend development of predictive models from statistics to machine learning is the subject of this review. Gathered from the Google Scholar database, 14 appropriate papers (2016-2020) related to the rice phenotypes prediction were selected through title and abstract content filtering. The outputs show that Support Vector Machine, Multi-layer Perceptron, and regression are the most used models, while yield is the priority prediction point besides tiller, panicle, and 1000-grain weight of rice. However, finding the accurate predictor is invariably challenging due to distinct rice varieties in the world and high confounding factors. Thus, developing an advanced deep learning model that accommodates these needs is worth considering further. © 2023 The Authors. Published by Elsevier B.V.

关键词： machine learning rice phenotypes prediction statistics

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A review: data pre-processing techniques used for diabetes prediction 9th

A review: Data pre-processing techniques used for diabetes p...

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9th International Conference on Computer science and Computational Intelligence, ICCSCI 2024

作者： Isnan, Mahmud Elwirehardja, Gregorius Natanael Pardamean, Bens Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia Computer Science Department School of Computer Science Bina Nusantara University Jakarta11480 Indonesia Cmputer Science Department BINUS Graduate Program Computer Science Program Bina Nusantara University Jakarta11480 Indonesia

When processing datasets in diabetes classification, common problems included a large number of missing values, outliers, and dataset imbalance. To deal with those issues, this study analyzed 18 studies on diabetes classification with machine learning algorithms over the past 5 years. This revealed the important role of data pre-processing in creating effective classification models, as it was found that by using different data pre-processing techniques, the same model can provide different performance. The study identified K-Nearest Neighbor (KNN) and support vector machine (SVM) as superior methods for filling in missing values, achieving an accuracy of 98.49% and 94.89%, respectively. These approaches outperformed traditional methods such as median or mean replacement. However, the challenge of imbalanced data sets remains in all studies reviewed. The common evaluation metrics used to evaluate the created models in previous studies included accuracy, precision, specificity, sensitivity/recall, and F1 Score. Overall, this review showed that the role of data pre-processing is no less important than algorithm selection to improve the performance of machine learning models in diabetes classification. © 2024 The Authors.

关键词： Adversarial machine learning

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Machine Learning Approach for Single Nucleotide Polymorphism Selection in Genetic Testing Results 8

Machine Learning Approach for Single Nucleotide Polymorphism...

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8th International Conference on Computer science and Computational Intelligence, ICCSCI 2023

作者： Trinugroho, Joko Pebrianto Hidayat, Alam Ahmad Isnan, Mahmud Pardamean, Bens Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia Department of Mathematics School of Computer Science Bina Nusantara University Jakarta11480 Indonesia Computer Science Department BINUS Graduate Program Bina Nusantara University Jakarta11480 Indonesia

Lactose intolerance is a type of digestive problem that may threaten the population because milk and dairy products compose of nutrients that are essential for human body. Genetic tests possess a great potential to detect lactose intolerance as it can be used in children and even infants. However, a new approach to analyze the genetic test results is needed to elucidate the Single Nucleotide Polymorphisms (SNPs) that are related to lactose intolerance. In this work, we utilized the machine learning based feature selection to select the SNPs associated with lactose tolerance trait from genotyping samples of direct-to-customer (DTCG genetic tests, obtained from the public database. Recursive Feature Elimination (RFE) with XGBoost model was used to perform feature selection. We also compared three different models, such as XGBoost, support vector machine (SVM), and random forest (RF) for training the selected features. Our findings revealed that 20 SNPs (out of 3501) were chosen, with rs4394668 as the most important variables (F-score 0.009). Furthermore, when compared to the RF and SVM models, the XGBoost model had the highest accuracy (0.87). Further studies should be undertaken to elucidate how the selected SNPs may lead to the lactose intolerance trait. © 2023 The Authors. Published by Elsevier B.V.

关键词： feature selection genetic test lactose intolerance SNP

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UniSleepPos: Sleep Posture Identification System Utilizing Millimeter-wave Radar

UniSleepPos: Sleep Posture Identification System Utilizing M...

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2024 IEEE International Conference on bioinformatics and Biomedicine, BIBM 2024

作者： Liu, Kun Li, Min He, Chu Tian, Xu Mao, Junbin Zeng, Min Liu, Jin Xinjiang University Xinjiang Engineering Research Center of Big Data and Intelligent Software School of Software Urumqi China Central South University Hunan Provincial Key Lab on Bioinformatics School of Computer Science and Engineering Changsha China

ISBN: (纸本)9798350386226

Sleep posture identification is crucial for accurately assessing sleep quality and diagnosing related diseases. In the realm of non-intrusive sleep monitoring, non-contact technologies are becoming increasingly mainstream. Millimeter-wave radar is frequently utilized in sleep posture identification due to its high resolution, strong penetration, and excellent sensitivity. However, traditional radar-based methods for sleep posture identification often struggle with reliability when dealing with diverse individuals and complex sleep environments. To address these challenges, we propose UniSleepPos, which designs a novel dual-view fusion mechanism to integrate depression and elevation angle signals obtained from radar, thus accurately capturing the posture information of the monitored subject in three-dimensional space. Furthermore, we combine sleep posture identification with individual characteristics, utilizing existing individual labels as prior knowledge to assist in sleep posture identification. The integration of prior knowledge provides a valuable information source for the model, helping to enhance its understanding of the data and improve its performance. We collected sleep posture data from eight volunteers using millimeter-wave radar devices under various environmental conditions. Leave-one-subject-out experiments were conducted to validate the effectiveness of UniSleepPos. The results indicated that UniSleepPos significantly outperforms existing methods, demonstrating its potential for practical applications. © 2024 IEEE.

关键词： Sleep research

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BERT-based Topic Modeling Approach for Malaria research Publication 4

BERT-based Topic Modeling Approach for Malaria Research Publ...

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4th International Conference on Informatics, Multimedia, Cyber and Information System, ICIMCIS 2022

作者： Hidayat, Alam Ahmad Nirwantono, Rudi Budiarto, Arif Pardamean, Bens Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia School of Computer Science Bina Nusantara University Computer Science Department Jakarta11480 Indonesia Bina Nusantara University Binus Graduate Program - Master of Computer Science Computer Science Department Jakarta11480 Indonesia

ISBN: (纸本)9781665473279

Malaria is a communicable disease with half of the global population at risk due to its high morbidity and mortality rates. A massive number of studies are dedicated to malaria research, so it plays a key role in formulating the proper prevention strategy and effective malaria treatment. With the overwhelming number of updated publications in the field, an unsupervised text mining approach such as topic modeling may provide an alternative method for the malaria researcher to keep pace with new insights. In this work, we collect metadata of malaria publications from the PubMed database to perform BERT-based topic modeling to find well-defined topics regarding malaria research. The method is largely based on the popular BERTopic pipeline. We compare the performance of three different language models to generate document embeddings from the data. The dimension reduction and the density-based clustering algorithm are used to cluster the embeddings. The topic representation is computed based on the semantic similarity of the class TF-IDF representation. The substance of the resulting topics is then manually annotated based on the top words of each topic. We demonstrate that by merging initial topics into larger topics using hierarchical clustering and manual content-based examination, the evaluated coherence measure can be further improved, thus enhancing the topic's interpretability. Our modeling result is able to extract ten major topics recurring in the malaria research publication published from 2017-2022. The result provides preliminary insight to understand the dynamics and patterns of malaria research over the years © 2022 IEEE.

关键词： Diseases

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Repurposing transfer learning strategy of computer vision for owl sound classification 7

Repurposing transfer learning strategy of computer vision fo...

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7th International Conference on Computer science and Computational Intelligence, CSCI 2022

作者： Gunawan, Kevin William Hidayat, Alam Ahmad Cenggoro, Tjeng Wawan Pardamean, Bens Computer Science Department BINUS Graduate Program-Master of Computer Science Bina Nusantara University Jakarta11480 Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia Computer Science Department School of Computer Science Bina Nusantara University Jakarta11480 Indonesia

Accurately predicting an owl species based on its sound can be helpful for owl conservation. To build an accurate model for owl sound classification, deep learning is currently the most preferred algorithm, due to its excellent performance for modeling audio data. However, deep learning is generally underperformed for a small dataset, which is the case for recognizing scops owl sound. To overcome the issue, we proposed a transfer learning strategy, which is common for computer vision tasks, that can alleviate overfitting in a deep learning model for the owl sound classification. In our approach, we propose a neural network architecture consisting of the backbone of a EfficientNet model pre-Trained on the massive ImageNet database. The model takes the sound input that has been converted as two image representations: Spectrogram and Mel Frequency Cepstral Coefficients. Our strategy enables the use of a relatively small size of pre-Trained image classification model, which is widely available, for transfer learning in owl sound classification. Deploying the lightweight model in an automatic sound classifier provides a fast and accurate tool for various owl conservation purposes. © 2022 Elsevier B.V.. All rights reserved.

关键词： Deep learning

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Expert system for oil palm leaves deficiency to support precision agriculture 6

Expert system for oil palm leaves deficiency to support prec...

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6th International Conference on Information Management and Technology, ICIMTech 2021

作者： Putra, Dian Pratama Bimantio, Prasanto Suparyanto, Teddy Pardamean, Bens Institute of Agriculture STIPER Agrotechnology Department Yogyakarta55281 Indonesia Institute of Agriculture STIPER Agricultural Engineering Department Yogyakarta55281 Indonesia Research Center Bina Nusantara University Bioinformatics and Data Science Jakarta11480 Indonesia

ISBN: (纸本)9781665449373

Expert systems are an option in the implementation of agricultural cultivation, which can provide comprehensive information to make crop cultivation more precise. The expert program currently used in oil palm plants is still unable to provide accurate information on actual deficiencies. Thus, there is a need for an expert system that can provide valid information. This research creates an expert system in agriculture that can help farmers to make decisions by knowing the types of nutrient deficiencies in oil palm. Besides that, it can help the process of disseminating information and knowledge through applications that can be accessed at any time by farmers to save time and money and support their existence. Edge detection using the Sobel method and the Robert method using the High Pass Filter (HPF) is the basis for this expert system creation method. This expert system can be used for any type of mature oil palm plant where yellow spots are found, due to a lack of nutrients or deficiency. Diseases that arise due to deficiencies depend on each nutrient, in this study all deficiencies are specific to the upper part of the plant, namely leaves. Tests carried out 15 times resulted in the deficiency most often raised by oil palm trees due to the lack of primary essential nutrients, namely nitrogen nutrients. The validation assessment is then carried out by an expert (human) directly and assesses the deficiency directly, then from the results of the test and assessment, there are 11 images from 15 images that match the assessment by the expert. © 2021 IEEE.

关键词： High pass filters

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Multi-Task Learning for Alzheimer's Disease Diagnosis and Mini-Mental State Examination Score Prediction

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Big data Mining and Analytics 2024年第3期7卷 828-842页

作者： Jin Liu Xu Tian Hanhe Lin Hong-Dong Li Yi Pan Hunan Provincial Key Lab on Bioinformatics School of Computer Science and EngineeringCentral South UniversityChangsha 410083China Xinjiang Engineering Research Center of Big Data and Intelligent Software School of SoftwareXinjiang UniversityUrumqi 830091China School of Science and Engineering University of DundeeDundeeDD14HNUK Faculty of Computer Science and Control Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

Accurately diagnosing Alzheimer's disease is essential for improving elderly ***,accurate prediction of the mini-mental state examination score also can measure cognition impairment and track the progression of Alzheimer's ***,most of the existing methods perform Alzheimer's disease diagnosis and mini-mental state examination score prediction separately and ignore the relation between these two *** address this challenging problem,we propose a novel multi-task learning method,which uses feature interaction to explore the relationship between Alzheimer's disease diagnosis and minimental state examination score *** our proposed method,features from each task branch are firstly decoupled into candidate and non-candidate parts for ***,we propose feature sharing module to obtain shared features from candidate features and return shared features to task branches,which can promote the learning of each *** validate the effectiveness of our proposed method on multiple *** Alzheimer's disease neuroimaging initiative 1 dataset,the accuracy in diagnosis task and the root mean squared error in prediction task of our proposed method is 87.86%and 2.5,*** results show that our proposed method outperforms most state-of-the-art *** proposed method enables accurate Alzheimer's disease diagnosis and mini-mental state examination score ***,it can be used as a reference for the clinical diagnosis of Alzheimer's disease,and can also help doctors and patients track disease progression in a timely manner.

关键词： multi-task learning Alzheimer's disease diagnosis mini-mental state examination score prediction

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Machine Learning Approaches in Detecting Autism Spectrum Disorder 8

Machine Learning Approaches in Detecting Autism Spectrum Dis...

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8th International Conference on Computer science and Computational Intelligence, ICCSCI 2023

作者： Daniel Dominic, Nicholas Cenggoro, Tjeng Wawan Pardamean, Bens Computer Science Department BINUS Graduate Program - Master of Computer Science Program Bina Nusantara University Jakarta11480 Indonesia Computer Science Department School of Computer Science Bina Nusantara University Jakarta11480 Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia

Early detection of Autism Spectrum Disorder (ASD) needs to be increased to prevent further adverse impacts. Thus, the classification between ASD and Typically Development (TD) individuals is an intriguing task. This review study has collected 26 related papers to answer four research questions, i.e., what are the most used data inputs, brain atlases, and machine learning models for ASD classification, as also to discover the significant parts of the brain correlated with the ASD. It was eventually found that functional connectivity matrix, Support Vector Machine, and CC200 are the most frequently used data input, model, and brain atlas, respectively. researchers also concluded that the posterior temporal fusiform cortex, intracalcarine cortex, cuneal cortex, subcallosal cortex, occipital pole, and lateral occipital cortex are the brain regions highly correlated with ASD. © 2023 The Authors. Published by Elsevier B.V.

关键词： autism spectrum disorder brain atlas brain region machine learning

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