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Worldwide Soundscapes: A Synthesis of Passive Acoustic Monitoring Across Realms

Global Ecology and Biogeography 2025年第5期34卷

作者： Kevin F. A. Darras Rodney A. Rountree Steven L. Van Wilgenburg Anna F. Cord Frederik Pitz Youfang Chen Lijun Dong Agnès Rocquencourt Camille Desjonquères Patrick Mauritz Diaz Tzu-Hao Lin Théophile Turco Louise Emmerson Tom Bradfer-Lawrence Amandine Gasc Sarah Marley Marcus Salton Laura Schillé Paul J. Wensveen Shih-Hung Wu Adriana C. Acero-Murcia Orlando Acevedo-Charry Matyáš Adam Jacopo Aguzzi Irmak Akoglu M. Clara P. Amorim Mina Anders Michel André Alexandre Antonelli Leandro Aparecido Do Nascimento Giulliana Appel Stephanie Archer Christos Astaras Andrey Atemasov Jamieson Atkinson Joël Attia Emanuel Baltag Luc Barbaro Fritjof Basan Carly Batist Julio Ernesto Baumgarten Just T. Bayle Sempere Kristen Bellisario Asaf Ben David Oded Berger-Tal Frédéric Bertucci Matthew G. Betts Iqbal S. Bhalla Thiago Bicudo Marta Bolgan Sara Bombaci Gerard Bota Martin Boullhesen Robert A. Briers Susannah Buchan Michal Budka Katie Burchard Giuseppa Buscaino Alice Calvente Marconi Campos-Cerqueira Maria Isabel Carvalho Gonçalves Maria Ceraulo Maite Cerezo-Araujo Gunnar Cerwén Adams A. Chaskda Maria Chistopolova Christopher W. Clark Kieran D. Cox Benjamin Cretois Chapin Czarnecki Luis P. da Silva Wigna da Silva Laurence H. De Clippele David de la Haye Ana Silvia de Oliveira Tissiani Devin de Zwaan M. Eugenia Degano Jessica Deichmann Joaquin del Rio Christian Devenish Ricardo Díaz-Delgado Pedro Diniz Dorgival Diógenes Oliveira-Júnior Thiago Dorigo Saskia Dröge Marina Duarte Adam Duarte Kerry Dunleavy Robert Dziak Simon Elise Hiroto Enari Haruka S. Enari Florence Erbs Britas Klemens Eriksson Pınar Ertör-Akyazi Nina C. Ferrari Luane Ferreira Abram B. Fleishman Paulo J. Fonseca Bárbara Freitas Nicholas R. Friedman Jérémy S. P. Froidevaux Svetlana Gogoleva Carolina Gonzaga José Miguel González Correa Eben Goodale Benjamin Gottesman Ingo Grass Jack Greenhalgh Jocelyn Gregoire Samuel Haché Jonas Hagge William Halliday Antonia Hammer Tara Hanf-Dressler Sylvain Haupert Samara Haver Becky Heath Daniel Hending Jose Hernandez-Blanco Dennis Higgs EFNO ECODIV INRAE Domaine des Barres Nogent-sur-Vernisson France Sustainable Agricultural Systems & Engineering Lab School of Engineering Westlake University Hangzhou Zhejiang China Chair of Computational Landscape Ecology Faculty of Environmental Sciences Dresden University of Technology Dresden Germany Biology Department University of Victoria Victoria British Columbia Canada The Fish Listener Waguoit Massachusetts USA Terrestrial Unit Prairie Region Canadian Wildlife Service Environment & Climate Change Canada Prairie & Northern Wildlife Research Centre Saskatoon Saskatchewan Canada Agro-ecological Modeling Group Faculty of Agriculture University of Bonn Bonn Germany Marine Mammal and Marine Bioacoustics Laboratory Department of Deep Sea Science Institute of Deep-sea Science and Engineering Chinese Academy of Sciences Sanya Hainan China Institut de Systématique Évolution Biodiversité Muséum National d’Histoire Naturelle Paris France Université Grenoble Alpes Université Savoie Mont Blanc CNRS LECA Grenoble France Climate Change and Biodiversity Hanns R. Neumann Stiftung Indonesia Muaradua Indonesia Biodiversity Research Center Academia Sinica Nankang Taipei Taiwan ENES Bioacoustics Research Laboratory University of Saint-Etienne CRNL CNRS UMR 5292 Inserm UMR_S 1028 Saint-Etienne France Australian Antarctic Division Science Branch Department of Climate Change Energy Environment and Water Channel Highway Kingston Tasmania Australia Biological and Environmental Sciences University of Stirling Stirling Scotland Centre for Conservation Science RSPB Edinburgh UK IMBE Aix Marseille Univ Avignon Univ CNRS IRD Aix-en-Provence France Scotland's Rural College Craibstone Estate Aberdeen UK BIOGECO INRAE University of Bordeaux Cestas France Westman Islands Research Centre University of Iceland Vestmannaeyjar Iceland Qigu Research Center Taiwan Biodiversity Research Institute Nantou County Taiwan Programa de Pós-graduação em Ecologia

Aim The urgency for remote, reliable and scalable biodiversity monitoring amidst mounting human pressures on ecosystems has sparked worldwide interest in Passive Acoustic Monitoring (PAM), which can track life underwater and on land. However, we lack a unified methodology to report this sampling effort and a comprehensive overview of PAM coverage to gauge its potential as a global research and monitoring tool. To address this gap, we created the Worldwide Soundscapes project, a collaborative network and growing database comprising metadata from 416 datasets across all realms (terrestrial, marine, freshwater and subterranean). Location Worldwide, 12,343 sites, all ecosystem types. Time Period 1991 to present. Major Taxa Studied All soniferous taxa. Methods We synthesise sampling coverage across spatial, temporal and ecological scales using metadata describing sampling locations, deployment schedules, focal taxa and audio recording parameters. We explore global trends in biological, anthropogenic and geophysical sounds based on 168 selected recordings from 12 ecosystems across all realms. Results Terrestrial sampling is spatially denser (46 sites per million square kilometre—Mkm 2 ) than aquatic sampling (0.3 and 1.8 sites/Mkm 2 in oceans and fresh water) with only two subterranean datasets. Although diel and lunar cycles are well sampled across realms, only marine datasets (55%) comprehensively sample all seasons. Across the 12 ecosystems selected for exploring global acoustic trends, biological sounds showed contrasting diel patterns across ecosystems, declined with distance from the Equator, and were negatively correlated with anthropogenic sounds. Main Conclusions PAM can inform macroecological studies as well as global conservation and phenology syntheses, but representation can be improved by expanding terrestrial taxonomic scope, sampling coverage in the high seas and subterranean ecosystems, and spatio-temporal replication in freshwater habitats. Overall, this

关键词： ARU automated sound recorder biodiversity conservation biology ecoacoustics IUCN GET realm Passive Acoustic Monitoring phenology soundscape ecology

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Author Correction: Ongoing declines for the world's amphibians in the face of emerging threats

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Nature 2024年第7993期625卷 E2页

作者： Jennifer A Luedtke Janice Chanson Kelsey Neam Louise Hobin Adriano O Maciel Alessandro Catenazzi Amaël Borzée Amir Hamidy Anchalee Aowphol Anderson Jean Ángel Sosa-Bartuano Ansel Fong G Anslem de Silva Antoine Fouquet Ariadne Angulo Artem A Kidov Arturo Muñoz Saravia Arvin C Diesmos Atsushi Tominaga Biraj Shrestha Brian Gratwicke Burhan Tjaturadi Carlos C Martínez Rivera Carlos R Vásquez Almazán Celsa Señaris S R Chandramouli Christine Strüssmann Claudia Fabiola Cortez Fernández Claudio Azat Conrad J Hoskin Craig Hilton-Taylor Damion L Whyte David J Gower Deanna H Olson Diego F Cisneros-Heredia Diego José Santana Elizah Nagombi Elnaz Najafi-Majd Evan S H Quah Federico Bolaños Feng Xie Francisco Brusquetti Francisco S Álvarez Franco Andreone Frank Glaw Franklin Enrique Castañeda Fred Kraus Gabriela Parra-Olea Gerardo Chaves Guido F Medina-Rangel Gustavo González-Durán H Mauricio Ortega-Andrade Iberê F Machado Indraneil Das Iuri Ribeiro Dias J Nicolas Urbina-Cardona Jelka Crnobrnja-Isailović Jian-Huan Yang Jiang Jianping Jigme Tshelthrim Wangyal Jodi J L Rowley John Measey Karthikeyan Vasudevan Kin Onn Chan Kotambylu Vasudeva Gururaja Kristiina Ovaska Lauren C Warr Luis Canseco-Márquez Luís Felipe Toledo Luis M Díaz M Monirul H Khan Madhava Meegaskumbura Manuel E Acevedo Marcelo Felgueiras Napoli Marcos A Ponce Marcos Vaira Margarita Lampo Mario H Yánez-Muñoz Mark D Scherz Mark-Oliver Rödel Masafumi Matsui Maxon Fildor Mirza D Kusrini Mohammad Firoz Ahmed Muhammad Rais N'Goran G Kouamé Nieves García Nono Legrand Gonwouo Patricia A Burrowes Paul Y Imbun Philipp Wagner Philippe J R Kok Rafael L Joglar Renoir J Auguste Reuber Albuquerque Brandão Roberto Ibáñez Rudolf von May S Blair Hedges S D Biju S R Ganesh Sally Wren Sandeep Das Sandra V Flechas Sara L Ashpole Silvia J Robleto-Hernández Simon P Loader Sixto J Incháustegui Sonali Garg Somphouthone Phimmachak Stephen J Richards Tahar Slimani Tamara Osborne-Naikatini Tatianne P F Abreu-Jardim Thais H Condez Thiago R De Carvalho Timothy P Cutajar Todd W Pierson Truong Re:wild Austin TX USA. jluedtke@***. IUCN SSC Amphibian Specialist Group Toronto Ontario Canada. jluedtke@***. Re:wild Austin TX USA. IUCN SSC Amphibian Specialist Group Toronto Ontario Canada. Museu Paraense Emílio Goeldi CZO/Herpetologia Belém Brazil. Florida International University Miami FL USA. Centro de Ornitologia y Biodiversidad (CORBIDI) Lima Peru. Laboratory of Animal Behaviour and Conservation College of Life Sciences Nanjing Forestry University Nanjing People's Republic of China. Laboratory of Herpetology Museum Zoologicum Bogoriense Research Center for Biosystematics and Evolution National Research and Innovation Agency (BRIN) Cibinong Indonesia. Department of Zoology Faculty of Science Kasetsart University Bangkok Thailand. Action Pour la Sauvegarde de l'Ecologie en Haïti (ACSEH) Les Cayes Haiti. Environmental Protection In the Caribbean (EPIC) Maho Sint Maarten. Museo de Vertebrados de la Universidad de Panamá Ciudad de Panama Panama. Centro Oriental de Ecosistemas y Biodiversidad (BIOECO) Museo de Historia Natural "Tomás Romay" Santiago de Cuba Cuba. IUCN SSC Amphibian Specialist Group Sri Lanka Gampola Sri Lanka. Laboratoire Évolution & Diversité Biologique UMR 5174 Université Toulouse III Paul Sabatier Toulouse France. Russian State Agrarian University-MTAA Moscow Russia. IUCN SSC Amphibian Specialist Group Bolivia La Paz Bolivia. Animal Nutrition Unit Department of Veterinary and Biosciences Ghent University Ghent Belgium. ASEAN Centre for Biodiversity University of the Philippines Los Baños Laguna Philippines. HerpWatch Pilipinas Manila Philippines. Faculty of Education University of the Ryukyus Okinawa Japan. Graduate School of Engineering and Science University of the Ryukyus Okinawa Japan. SAVE THE FROGS! Laguna Beach CA USA. The University of Texas at Arlington Arlington TX USA. Smithsonian Conservation Biology Institute Front Royal VA USA. Center for Environmental Studies Sanata Dharma University (CESSDU) Yogya

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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

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Nature 2024年第8003期627卷 347-357页

作者： Ken Suzuki Konstantinos Hatzikotoulas Lorraine Southam Henry J Taylor Xianyong Yin Kim M Lorenz Ravi Mandla Alicia Huerta-Chagoya Giorgio E M Melloni Stavroula Kanoni Nigel W Rayner Ozvan Bocher Ana Luiza Arruda Kyuto Sonehara Shinichi Namba Simon S K Lee Michael H Preuss Lauren E Petty Philip Schroeder Brett Vanderwerff Mart Kals Fiona Bragg Kuang Lin Xiuqing Guo Weihua Zhang Jie Yao Young Jin Kim Mariaelisa Graff Fumihiko Takeuchi Jana Nano Amel Lamri Masahiro Nakatochi Sanghoon Moon Robert A Scott James P Cook Jung-Jin Lee Ian Pan Daniel Taliun Esteban J Parra Jin-Fang Chai Lawrence F Bielak Yasuharu Tabara Yang Hai Gudmar Thorleifsson Niels Grarup Tamar Sofer Matthias Wuttke Chloé Sarnowski Christian Gieger Darryl Nousome Stella Trompet Soo-Heon Kwak Jirong Long Meng Sun Lin Tong Wei-Min Chen Suraj S Nongmaithem Raymond Noordam Victor J Y Lim Claudia H T Tam Yoonjung Yoonie Joo Chien-Hsiun Chen Laura M Raffield Bram Peter Prins Aude Nicolas Lisa R Yanek Guanjie Chen Jennifer A Brody Edmond Kabagambe Ping An Anny H Xiang Hyeok Sun Choi Brian E Cade Jingyi Tan K Alaine Broadaway Alice Williamson Zoha Kamali Jinrui Cui Manonanthini Thangam Linda S Adair Adebowale Adeyemo Carlos A Aguilar-Salinas Tarunveer S Ahluwalia Sonia S Anand Alain Bertoni Jette Bork-Jensen Ivan Brandslund Thomas A Buchanan Charles F Burant Adam S Butterworth Mickaël Canouil Juliana C N Chan Li-Ching Chang Miao-Li Chee Ji Chen Shyh-Huei Chen Yuan-Tsong Chen Zhengming Chen Lee-Ming Chuang Mary Cushman John Danesh Swapan K Das H Janaka de Silva George Dedoussis Latchezar Dimitrov Ayo P Doumatey Shufa Du Qing Duan Kai-Uwe Eckardt Leslie S Emery Daniel S Evans Michele K Evans Krista Fischer James S Floyd Ian Ford Oscar H Franco Timothy M Frayling Barry I Freedman Pauline Genter Hertzel C Gerstein Vilmantas Giedraitis Clicerio González-Villalpando Maria Elena González-Villalpando Penny Gordon-Larsen Myron Gross Lindsay A Guare Sophie Hackinger Liisa Hakaste Sohee Han Andrew T Hattersley Christian Herder Momoko Horikoshi Annie-Green Howard Willa Centre for Genetics and Genomics Versus Arthritis Centre for Musculoskeletal Research Division of Musculoskeletal and Dermatological Sciences University of Manchester Manchester UK. Department of Diabetes and Metabolic Diseases Graduate School of Medicine University of Tokyo Tokyo Japan. Department of Statistical Genetics Osaka University Graduate School of Medicine Suita Japan. Institute of Translational Genomics Helmholtz Zentrum München German Research Center for Environmental Health Neuherberg Germany. konstantinos.hatzikotoulas@helmholtz-munich.de. Institute of Translational Genomics Helmholtz Zentrum München German Research Center for Environmental Health Neuherberg Germany. Center for Precision Health Research National Human Genome Research Institute National Institutes of Health Bethesda MD USA. British Heart Foundation Cardiovascular Epidemiology Unit Department of Public Health and Primary Care University of Cambridge Cambridge UK. Heart and Lung Research Institute University of Cambridge Cambridge UK. Department of Epidemiology School of Public Health Nanjing Medical University Nanjing China. Department of Biostatistics and Center for Statistical Genetics University of Michigan Ann Arbor MI USA. Corporal Michael J. Crescenz VA Medical Center Philadelphia PA USA. Department of Systems Pharmacology and Translational Therapeutics University of Pennsylvania Perelman School of Medicine Philadelphia PA USA. Department of Genetics University of Pennsylvania Perelman School of Medicine Philadelphia PA USA. Programs in Metabolism and Medical and Population Genetics Broad Institute of Harvard and MIT Cambridge MA USA. Diabetes Unit and Center for Genomic Medicine Massachusetts General Hospital Boston MA USA. TIMI Study Group Division of Cardiovascular Medicine Brigham and Women's Hospital Harvard Medical School Boston MA USA. William Harvey Research Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London L

Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms that are often specific to cell type. Here, to characterize the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study data from 2,535,601 individuals (39.7% not of European ancestry), including 428,452 cases of T2D. We identify 1,289 independent association signals at genome-wide significance (P < 5 × 10) that map to 611 loci, of which 145 loci are, to our knowledge, previously unreported. We define eight non-overlapping clusters of T2D signals that are characterized by distinct profiles of cardiometabolic trait associations. These clusters are differentially enriched for cell-type-specific regions of open chromatin, including pancreatic islets, adipocytes, endothelial cells and enteroendocrine cells. We build cluster-specific partitioned polygenic scores in a further 279,552 individuals of diverse ancestry, including 30,288 cases of T2D, and test their association with T2D-related vascular outcomes. Cluster-specific partitioned polygenic scores are associated with coronary artery disease, peripheral artery disease and end-stage diabetic nephropathy across ancestry groups, highlighting the importance of obesity-related processes in the development of vascular outcomes. Our findings show the value of integrating multi-ancestry genome-wide association study data with single-cell epigenomics to disentangle the aetiological heterogeneity that drives the development and progression of T2D. This might offer a route to optimize global access to genetically informed diabetes care.

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Author Correction: GLORIA - A globally representative hyperspectral in situ dataset for optical sensing of water quality

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Scientific data 2023年第1期10卷 191页

作者： Moritz K Lehmann Daniela Gurlin Nima Pahlevan Krista Alikas Ted Conroy Janet Anstee Sundarabalan V Balasubramanian Cláudio C F Barbosa Caren Binding Astrid Bracher Mariano Bresciani Ashley Burtner Zhigang Cao Arnold G Dekker Courtney Di Vittorio Nathan Drayson Reagan M Errera Virginia Fernandez Dariusz Ficek Cédric G Fichot Peter Gege Claudia Giardino Anatoly A Gitelson Steven R Greb Hayden Henderson Hiroto Higa Abolfazl Irani Rahaghi Cédric Jamet Dalin Jiang Thomas Jordan Kersti Kangro Jeremy A Kravitz Arne S Kristoffersen Raphael Kudela Lin Li Martin Ligi Hubert Loisel Steven Lohrenz Ronghua Ma Daniel A Maciel Tim J Malthus Bunkei Matsushita Mark Matthews Camille Minaudo Deepak R Mishra Sachidananda Mishra Tim Moore Wesley J Moses Hà Nguyễn Evlyn M L M Novo Stéfani Novoa Daniel Odermatt David M O'Donnell Leif G Olmanson Michael Ondrusek Natascha Oppelt Sylvain Ouillon Waterloo Pereira Filho Stefan Plattner Antonio Ruiz Verdú Salem I Salem John F Schalles Stefan G H Simis Eko Siswanto Brandon Smith Ian Somlai-Schweiger Mariana A Soppa Evangelos Spyrakos Elinor Tessin Hendrik J van der Woerd Andrea Vander Woude Ryan A Vandermeulen Vincent Vantrepotte Marcel R Wernand Mortimer Werther Kyana Young Linwei Yue Xerra Earth Observation Institute PO Box 400 Alexandra 9340 New Zealand. moritz.lehmann@***. School of Science University of Waikato Private Bag 3105 Hamilton 3240 New Zealand. moritz.lehmann@***. Wisconsin Department of Natural Resources Bureau of Water Quality 101 S Webster Street Madison WI 53707 USA. Science Systems and Applications Inc. (SSAI) Lanham MD USA. NASA Goddard Space Flight Center Greenbelt MD USA. Tartu Observatory of the University of Tartu Tartumaa 61602 Estonia. School of Science University of Waikato Private Bag 3105 Hamilton 3240 New Zealand. Coasts and Oceans Systems Program (COS) CSIRO Environment Business Unit Acton ACT 2601 Australia. GeoSensing and Imaging Consultancy Trivandrum Kerala India. Instrumentation Lab for Aquatic Systems (LabISA) National Institute for Space Research (INPE) São José dos Campos Brazil. Environment and Climate Change Canada Burlington ON Canada. Phytooptics Group Physical Oceanography of Polar Seas Climate Sciences Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research Bremerhaven Germany. Department of Physics and Electrical Engineering Institute of Environmental Physics University of Bremen Bremen Germany. National Research Council of Italy Institute for Electromagnetic Sensing of the Environment CNR-IREA Milano Italy. Cooperative Institute for Great Lakes Research University of Michigan 4840 South State Road Ann Arbor MI 48108 USA. Nanjing Institute of Geography and Limnology Chinese Academy of Sciences Nanjing 210008 China. SatDek Pty Ltd 99 Read Rd Sutton NSW 2620 Australia. Wake Forest University Engineering 455 Vine Street Winston-Salem NC 27101 USA. NOAA Great Lakes Environmental Research Laboratory Ann Arbor MI USA. Department of Geography Universidad de la República Montevideo Uruguay. Institute of Biology and Earth Sciences Pomeranian University Arciszewskiego 22 76-200 Slupsk Poland. Department of Earth and Environment Boston University Boston

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Cladophialophora bantiana metabolites are efficient in the larvicidal and ovicidal control of Aedes aegypti, and Culex quinquefasciatus and have low toxicity in zebrafish embryo

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The science of the total environment 2022年 852卷 158502页

作者： Chinnasamy Ragavendran Govindasamy Balasubramani Cherian Tijo Venkatesan Manigandan Eliningaya J Kweka Pandi Karthika Palaniappan Sivasankar Adelina Thomas Devarajan Natarajan Ismini Nakouti Guilherme Malafaia Natural Drug Research Laboratory Department of Biotechnology School of Biosciences Periyar University Salem 636 011 Tamil Nadu India Department of Cariology Saveetha Dental College and Hospitals Saveetha Institute of Medical and Technical Sciences (SIMATS) Chennai 600 077 India. Electronic address: ragavan889@***. Department of Research and Innovation Saveetha School of Engineering Saveetha Institute of Medical and Technical Sciences (SIMATS) Chennai 602105 Tamil Nadu India. Department of Ocean Studies and Marine Biology Pondicherry University Port Blair Campus Brookshabad Port Blair Andamans 744112 India. University of Texas Health Science Center San Antonio TX USA. Division of Livestock and Human Diseases Vector Control Tropical Pesticides Research Institute P.O. Box 3024 Arusha Tanzania Department of Medical Parasitology and Entomology Catholic University of Health and Allied Sciences P.O. Box 1464 Mwanza Tanzania. Natural Drug Research Laboratory Department of Biotechnology School of Biosciences Periyar University Salem 636 011 Tamil Nadu India. Water Supply and Bioeconomy Division Faculty of Environmental Engineering and Energy Poznan University of Technology Berdychowo 4 60-965 Poznan Poland. School of Pharmacy Catholic University of Health and Allied Sciences P.O. Box 1464 Mwanza Tanzania. Centre for Natural Products Discovery (CNPD) School of Pharmacy and Biomolecular Sciences Liverpool John Moores University Liverpool L3 3AF UK. Laboratory of Toxicology Applied to the Environment Goiano Federal Institute Urutaí GO Brazil Post-Graduation Program in Conservation of Cerrado Natural Resources Goiano Federal Institute Urutaí GO Brazil Post-Graduation Program in Ecology Conservation and Biodiversity Federal University of Uberlândia Uberlândia MG Brazil Post-Graduation Program in Biotechnology and Biodiversity Federal University of Goiás Goiânia GO Brazil. Electronic address: guilhermeifgoiano@gmail.com.

Mosquitoes' current insecticide resistance status in available public health insecticides is a serious threat to mosquito control initiatives. Microbe-based control agents provide an alternative to conventional pesticides and insecticides, as they can be more targeted than synthetic insecticides. The present study was focused on identifying and investigating the mosquitocidal potential of Cladophialophora bantiana, an endophytic fungus isolated from Opuntia ficus-indica. The Cladophialophora species was identified through phylogenetic analysis of the rDNA sequence. The isolated fungus was first evaluated for its potential to produce metabolites against Aedes aegpti and Culex quinquefasciatus larvae in the 1-4th instar. The secondary metabolites of mycelium extract were assessed at various test doses (100, 200, 300, 400, and 500 μg/mL) in independent bioassays for each instar of selected mosquito larvae. After 48 h of exposure, A. aegypti expressed LC values of 13.069, 18.085, 9.554, and 11.717 μg/mL and LC = 25.702, 30.860, 17.275, and 19.601 μg/mL; followed by C. quinquefasciatus LC = 14.467, 11.766, 5.934, and 7.589 μg/mL, and LC = 29.529, 20.767, 11.192, and 13.296 μg/mL. The mean % of ovicidal bioassay was recorded 120 h after exposure. The hatchability (%) was proportional to mycelia metabolite concentration. The enzymatic level of acetylcholinesterase in fungal mycelial metabolite treated 4th instar larvae indicated a dose-dependent pattern. The GC-MS profile of C. bantiana extracts identified five of the most abundant compounds, namely cyclobutane, trans-3-undecene-1,5-diyne, 1-bromo-2-chloro, propane, 1,2,3-trichloro-2-methyl-, 5,5,10,10-tetrachlorotricyclo, and phenol, which had the killing effect in mosquitoes. Furthermore, the C. bantiana fungus ethyl acetate extracts had a strong larvicidal action on A. aegypti and C. quinquefasciatus. Finally, the toxicity test on zebrafish embryos revealed the induction of malformations only at concentrations above 1 m

关键词： Biopesticide Ecotoxicity Endophytic fungal Mosquitoes Vector control

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Beyond Low Earth Orbit: Biological Research, Artificial Intelligence, and Self-Driving Labs

arXiv

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arXiv 2021年

作者： Sanders, Lauren M. Yang, Jason H. Scott, Ryan T. Qutub, Amina Ann Martin, Hector Garcia Berrios, Daniel C. Hastings, Jaden J.A. Rask, Jon Mackintosh, Graham Hoarfrost, Adrienne L. Chalk, Stuart Kalantari, John Khezeli, Kia Antonsen, Erik L. Babdor, Joel Barker, Richard Baranzini, Sergio E. Beheshti, Afshin Delgado-Aparicio, Guillermo M. Glicksberg, Benjamin S. Greene, Casey S. Haendel, Melissa Hamid, Arif A. Heller, Philip Jamieson, Daniel Jarvis, Katelyn J. Komarova, Svetlana V. Komorowski, Matthieu Kothiyal, Prachi Mahabal, Ashish Manor, Uri Mason, Christopher E. Matar, Mona Mias, George I. Miller, Jack Myers, Jerry G. Nelson, Charlotte Oribello, Jonathan Park, Seung-Min Parsons-Wingerter, Patricia Prabhu, R.K. Reynolds, Robert J. Saravia-Butler, Amanda Saria, Suchi Sawyer, Aenor Singh, Nitin Kumar Soboczenski, Frank Snyder, Michael Soman, Karthik Theriot, Corey A. van Valen, David Venkateswaran, Kasthuri Warren, Liz Worthey, Liz Zitnik, Marinka Costes, Sylvain V. Blue Marble Space Institute of Science Space Biosciences Division NASA Ames Research Center Moffett Field CA94035 United States Center for Emerging and Re-Emerging Pathogens Department of Microbiology Biochemistry and Molecular Genetics Rutgers New Jersey Medical School NewarkNJ07103 United States KBR Space Biosciences Division NASA Ames Research Center Moffett Field CA94035 United States AI MATRIX Consortium Department of Biomedical Engineering University of Texas San Antonio and UT Health Sciences San AntonioTX78249 United States Biological Systems and Engineering Division Lawrence Berkeley National Lab. BerkeleyCA94608 United States DOE Agile BioFoundry EmeryvilleCA94608 United States Joint BioEnergy Institute EmeryvilleCA94608 United States Department of Physiology and Biophysics Weill Cornell Medicine New YorkNY10065 United States Office of the Center Director NASA Ames Research Center Moffett Field CA94035 United States Bay Area Environmental Research Institute NASA Ames Research Center Moffett Field CA94035 United States Space Biosciences Division NASA Ames Research Center Moffett Field CA94035 United States Department of Chemistry University of North Florida JacksonvilleFL32224 United States Center for Individualized Medicine Department of Surgery Department of Quantitative Health Sciences Mayo Clinic RochesterMN55905 United States Department of Emergency Medicine Center for Space Medicine Baylor College of Medicine HoustonTX77030 United States Department of Microbiology and Immunology Department of Otolaryngology Head and Neck Surgery University of California San Francisco San FranciscoCA94143 United States The Gilroy AstroBiology Research Group The University of Wisconsin - Madison MadisonWI53706 United States Weill Institute for Neurosciences Department of Neurology University of California San Francisco San FranciscoCA94158 United States Data Science Analytics Georgia Institute of Technology Lima15024

Space biology research aims to understand fundamental effects of spaceflight on organisms, develop foundational knowledge to support deep space exploration, and ultimately bioengineer spacecraft and habitats to stabilize the ecosystem of plants, crops, microbes, animals, and humans for sustained multi-planetary life. To advance these aims, the field leverages experiments, platforms, data, and model organisms from both spaceborne and ground-analog studies. As research is extended beyond low Earth orbit, experiments and platforms must be maximally autonomous, light, agile, and intelligent to expedite knowledge discovery. Here we present a summary of recommendations from a workshop organized by the National Aeronautics and Space Administration on artificial intelligence, machine learning, and modeling applications which offer key solutions toward these space biology challenges. In the next decade, the synthesis of artificial intelligence into the field of space biology will deepen the biological understanding of spaceflight effects, facilitate predictive modeling and analytics, support maximally autonomous and reproducible experiments, and efficiently manage spaceborne data and metadata, all with the goal to enable life to thrive in deep space. © 2021, CC BY.

关键词： Predictive analytics

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Beyond Low Earth Orbit: Biomonitoring, Artificial Intelligence, and Precision Space Health

arXiv

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arXiv 2021年

作者： Scott, Ryan T. Antonsen, Erik L. Sanders, Lauren M. Hastings, Jaden J.A. Park, Seung-Min Mackintosh, Graham Reynolds, Robert J. Hoarfrost, Adrienne L. Sawyer, Aenor Greene, Casey S. Glicksberg, Benjamin S. Theriot, Corey A. Berrios, Daniel C. Miller, Jack Babdor, Joel Barker, Richard Baranzini, Sergio E. Beheshti, Afshin Chalk, Stuart Delgado-Aparicio, Guillermo M. Haendel, Melissa Hamid, Arif A. Heller, Philip Jamieson, Daniel Jarvis, Katelyn J. Kalantari, John Khezeli, Kia Komarova, Svetlana V. Komorowski, Matthieu Kothiyal, Prachi Mahabal, Ashish Manor, Uri Martin, Hector Garcia Mason, Christopher E. Matar, Mona Mias, George I. Myers, Jerry G. Nelson, Charlotte Oribello, Jonathan Parsons-Wingerter, Patricia Prabhu, R.K. Qutub, Amina Ann Rask, Jon Saravia-Butler, Amanda Saria, Suchi Singh, Nitin Kumar Soboczenski, Frank Snyder, Michael Soman, Karthik van Valen, David Venkateswaran, Kasthuri Warren, Liz Worthey, Liz Yang, Jason H. Zitnik, Marinka Costes, Sylvain V. KBR Space Biosciences Division NASA Ames Research Center Moffett FieldCA94035 United States Department of Emergency Medicine Center for Space Medicine Baylor College of Medicine HoustonTX77030 United States Blue Marble Space Institute of Science Space Biosciences Division NASA Ames Research Center Moffett FieldCA94035 United States Department of Physiology and Biophysics Weill Cornell Medicine New YorkNY10065 United States Department of Urology Department of Radiology Stanford University School of Medicine StanfordCA94305 United States Bay Area Environmental Research Institute NASA Ames Research Center Moffett FieldCA94035 United States Mortality Research & Consulting Inc. HoustonTX77058 United States Space Biosciences Division NASA Ames Research Center Moffett FieldCA94035 United States UC Space Health Department of Orthopaedic Surgery University of California San Francisco San FranciscoCA94143 United States Center for Health AI Department of Biochemistry and Molecular Genetics University of Colorado School of Medicine Anschutz Medical Campus AuroraCO80045 United States Hasso Plattner Institute for Digital Health at Mount Sinai Department of Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai New YorkNY10065 United States Department of Preventive Medicine and Community Health UTMB GalvestonTX77551 United States Human Health and Performance Directorate NASA Johnson Space Center HoustonTX77058 United States Department of Microbiology and Immunology Department of Otolaryngology Head and Neck Surgery University of California San Francisco San FranciscoCA94143 United States The Gilroy AstroBiology Research Group The University of Wisconsin Madison MadisonWI53706 United States Weill Institute for Neurosciences Department of Neurology University of California San Francisco San FranciscoCA94158 United States Department of Chemistry University of North Florida JacksonvilleFL32224 United States Data Scienc

Human space exploration beyond low Earth orbit will involve missions of significant distance and duration. To effectively mitigate myriad space health hazards, paradigm shifts in data and space health systems are necessary to enable Earth-independence, rather than Earth-reliance. Promising developments in the fields of artificial intelligence and machine learning for biology and health can address these needs. We propose an appropriately autonomous and intelligent Precision Space Health system that will monitor, aggregate, and assess biomedical statuses;analyze and predict personalized adverse health outcomes;adapt and respond to newly accumulated data;and provide preventive, actionable, and timely insights to individual deep space crew members and iterative decision support to their crew medical officer. Here we present a summary of recommendations from a workshop organized by the National Aeronautics and Space Administration, on future applications of artificial intelligence in space biology and health. In the next decade, biomonitoring technology, biomarker science, spacecraft hardware, intelligent software, and streamlined data management must mature and be woven together into a Precision Space Health system to enable humanity to thrive in deep space. © 2021, CC BY.

关键词： Earth (planet)

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Surveillance of avian influenza through bird guano in remote regions of the global south to uncover transmission dynamics

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Nature communications 2025年第1期16卷 4900页

作者： Dhammika Leshan Wannigama Mohan Amarasiri Phatthranit Phattharapornjaroen Cameron Hurst Charin Modchang John Jefferson V Besa Kazuhiko Miyanaga Longzhu Cui Stefan Fernandez Angkana T Huang Puey Ounjai W K C P Werawatte Ali Hosseini Rad S M Porames Vatanaprasan Dylan John Jay Thammakorn Saethang Sirirat Luk-In Phitsanuruk Kanthawee Wanwara Thuptimdang Ratana Tacharoenmuang Bernadina Cynthia S P H Spencer Vitharana Natharin Ngamwongsatit Hitoshi Ishikawa Takashi Furukawa Yangzhong Wang Andrew C Singer Naveen Kumar Devanga Ragupathi Tanittha Chatsuwan Kazunari Sei Asuka Nanbo Asada Leelahavanichkul Talerngsak Kanjanabuch Hiroshi Hamamoto Paul G Higgins Daisuke Sano Anthony Kicic José O Valdebenito Jonas Bonnedahl Sam Trowsdale Parichart Hongsing Aisha Khatib Kenji Shibuya Shuichi Abe Department of Infectious Diseases Faculty of Medicine Yamagata University Yamagata Japan. leshanwannigama@med.id.yamagata-u.ac.jp. Department of Infectious Diseases and Infection Control Yamagata Prefectural Central Hospital Yamagata Japan. leshanwannigama@med.id.yamagata-u.ac.jp. Pathogen Hunter's Research Collaborative Team Department of Infectious Diseases and Infection Control Yamagata Prefectural Central Hospital Yamagata Japan. leshanwannigama@med.id.yamagata-u.ac.jp. Yamagata Prefectural University of Health Sciences Kamiyanagi Yamagata Japan. leshanwannigama@med.id.yamagata-u.ac.jp. The Lygodium Ceylon Health and Environmental Policy Research Center Colombo Sri Lanka. leshanwannigama@med.id.yamagata-u.ac.jp. Biofilms and Antimicrobial Resistance Consortium of ODA receiving countries The University of Sheffield Sheffield UK. leshanwannigama@med.id.yamagata-u.ac.jp. Pathogen Hunter's Research Collaborative Team Department of Infectious Diseases and Infection Control Yamagata Prefectural Central Hospital Yamagata Japan. Department of Civil and Environmental Engineering Graduate School of Engineering Tohoku University Sendai Miyagi Japan. Faculty of Health Science Technology Chulabhorn Royal Academy Bangkok Thailand. HRH Princess Chulabhorn Disaster and Emergency Medicine Center Chulabhorn Royal Academy Bangkok Thailand. Department of Clinical Epidemiology Faculty of Medicine Thammasat University Rangsit Thailand. Center of Excellence in Applied Epidemiology Thammasat University Rangsit Thailand. Mater Research Institute University of Queensland Brisbane QLD Australia. Biophysics Group Department of Physics Faculty of Science Mahidol University Bangkok Thailand. Centre of Excellence in Mathematics MHESI Bangkok Thailand. Thailand Center of Excellence in Physics Ministry of Higher Education Science Research and Innovation Bangkok Thailand. Department of Infectious Diseases and Infection Control Yamagata Prefectural Central Hospital Yamagata Japan. Co

Avian influenza viruses (AIVs) pose a growing global health threat, particularly in low- and middle-income countries (LMICs), where limited surveillance capacity and under-resourced healthcare systems hinder timely detection and response. Migratory birds play a significant role in the transboundary spread of AIVs, yet data from key regions along migratory flyways remain sparse. To address these surveillance gaps, we conducted a study between December 2021 and February 2023 using fresh bird guano collected across 10 countries in the Global South. Here, we show that remote, uninhabited regions in previously unsampled areas harbor a high diversity of AIV strains, with H5N1 emerging as the most prevalent. Some of these H5N1 samples also carry mutations that may make them less responsive to the antiviral drug oseltamivir. Our findings documented the presence of AIVs in several underrepresented regions and highlighted critical transmission hotspots where viral evolution may be accelerating. These results underscore the urgent need for geographically targeted surveillance to detect emerging variants, inform public health interventions, and reduce the risk of zoonotic spillover.

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Complete mitochondrial genome of the nesting Colombian Caribbean Hawksbill Turtle

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Mitochondrial DNA Part B 2017年第1期2卷 128-129页

作者： Javier Hernández-Fernández Gerson Beltrán-Torres Leonardo Mariño-Ramírez Deparment of Natural and Environmental Science Marine Biology Program Faculty of Science and Engineering Genetics Molecular Biology and Bioinformatic Research Group –GENBIMOL Jorge Tadeo Lozano University Bogotá Colombia National Center for Biotechnology Information National Library of Medicine National Institutes of Health Bethesda MD USA

The hawksbill turtle,Eretmochelis imbricata(Linnaeus, 1766), is an endangered sea turtle in Colombian Caribbean beach. In this study, we report the complete mitochondrial DNA sequences of hawksbill turtle. The entire genome comprised 16,386 base pairs, and a nucleotide frequency of T: 25.6%, C: 26.9%, A: G 35.4% and 12.1%. The mitogenome sequence of hawksbill turtle would contribute to better understand population genetics, and evolution of sea turtles. Molecule was deposited at the GenBank database under the accession number KP221806.

关键词： Testudines eretmochelys imbricata mitogenome endangered turtle

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Author Correction: π-HuB: the proteomic navigator of the human body

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Nature 2025年第8046期637卷 E22页

作者： Fuchu He Ruedi Aebersold Mark S Baker Xiuwu Bian Xiaochen Bo Daniel W Chan Cheng Chang Luonan Chen Xiangmei Chen Yu-Ju Chen Heping Cheng Ben C Collins Fernando Corrales Jürgen Cox Weinan E Jennifer E Van Eyk Jia Fan Pouya Faridi Daniel Figeys George Fu Gao Wen Gao Zu-Hua Gao Keisuke Goda Wilson Wen Bin Goh Dongfeng Gu Changjiang Guo Tiannan Guo Yuezhong He Albert J R Heck Henning Hermjakob Tony Hunter Narayanan Gopalakrishna Iyer Ying Jiang Connie R Jimenez Lokesh Joshi Neil L Kelleher Ming Li Yang Li Qingsong Lin Cui Hua Liu Fan Liu Guang-Hui Liu Yansheng Liu Zhihua Liu Teck Yew Low Ben Lu Matthias Mann Anming Meng Robert L Moritz Edouard Nice Guang Ning Gilbert S Omenn Christopher M Overall Giuseppe Palmisano Yaojin Peng Charles Pineau Terence Chuen Wai Poon Anthony W Purcell Jie Qiao Roger R Reddel Phillip J Robinson Paola Roncada Chris Sander Jiahao Sha Erwei Song Sanjeeva Srivastava Aihua Sun Siu Kwan Sze Chao Tang Liujun Tang Ruijun Tian Juan Antonio Vizcaíno Chanjuan Wang Chen Wang Xiaowen Wang Xinxing Wang Yan Wang Tobias Weiss Mathias Wilhelm Robert Winkler Bernd Wollscheid Limsoon Wong Linhai Xie Wei Xie Tao Xu Tianhao Xu Liying Yan Jing Yang Xiao Yang John Yates Tao Yun Qiwei Zhai Bing Zhang Hui Zhang Lihua Zhang Lingqiang Zhang Pingwen Zhang Yukui Zhang Yu Zi Zheng Qing Zhong Yunping Zhu State Key Laboratory of Medical Proteomics Beijing Proteome Research Center National Center for Protein Sciences (Beijing) Beijing Institute of Lifeomics Beijing China. hefc@***. International Academy of Phronesis Medicine (Guangdong) Guangdong China. hefc@***. Department of Biology Institute of Molecular Systems Biology ETH Zurich Zurich Switzerland. aebersold@imsb.biol.ethz.ch. Macquarie Medical School Macquarie University Sydney New South Wales Australia. Institute of Pathology and Southwest Cancer Center Southwest Hospital Third Military Medical University (Army Medical University) and Key Laboratory of Tumor Immunopathology Ministry of Education of China Chongqing China. Institute of Health Service and Transfusion Medicine Beijing China. Department of Pathology and The Sidney Kimmel Comprehensive Cancer Center Johns Hopkins University Baltimore MD USA. State Key Laboratory of Medical Proteomics Beijing Proteome Research Center National Center for Protein Sciences (Beijing) Beijing Institute of Lifeomics Beijing China. Key Laboratory of Systems Biology Center for Excellence in Molecular Cell Science Shanghai Institute of Biochemistry and Cell Biology Chinese Academy of Sciences Shanghai China. Department of Nephrology First Medical Center of Chinese PLA General Hospital Nephrology Institute of the Chinese People's Liberation Army State Key Laboratory of Kidney Diseases National Clinical Research Center for Kidney Diseases Beijing Key Laboratory of Kidney Disease Research Beijing China. Institute of Chemistry Academia Sinica Taipei China. National Biomedical Imaging Center State Key Laboratory of Membrane Biology Institute of Molecular Medicine Peking-Tsinghua Center for Life Sciences College of Future Technology Peking University Beijing China. School of Biological Sciences Queen's University of Belfast Belfast UK. Functional Proteomics Laboratory Centro Nacional de Biotecnología-CSIC Madrid Spain. Computational Systems Biochemistry Research Group Ma

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