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13th International Multi-Conference on Complexity, Informatics and Cybernetics, IMCIC 2022

作者： Hashimoto, Shigehiro Matsumoto, Taketo Uehara, Shogo Endo, Yoshiaki Biomedical Engineering Department of Mechanical Engineering Kogakuin University Tokyo163-8677 Japan Biomedical Engineering Systems Design Kogakuin University Tokyo163-8677 Japan Biomedical Engineering Mechanical Engineering Kogakuin University Tokyo163-8677 Japan

ISBN: (纸本)9781950492619

The bumping movement of the cell flowing over the oblique micro groove has been analyzed in comparison with the movement of the cell flowing outside groove in vitro. The micro flow-channel (0.05 mm high, 1 mm wide, 25 mm long) with grooves (4.5 μm deep) has been manufactured of polydimethylsiloxane (PDMS) by micromachining technique. The angle between the main flow direction and the longitudinal axis of the groove is 45 degrees. Variation has been made on the width (0.03 mm, 0.04 mm, and 0.05 mm) of the groove. Myoblast (C2C12: mouse myoblast cell line) was used in the test. A main flow velocity (0.02 mm/s © by the International Institute of Informatics and Systemics.

关键词： Cells

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Effect of Wall Shear Stress Field on Deformation Cycle of 3T3-L1 26

Effect of Wall Shear Stress Field on Deformation Cycle of 3T...

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26th World Multi-Conference on Systemics, Cybernetics and Informatics, WMSCI 2022

作者： Ono, Ryuya Hashimoto, Shigehiro Yonezawa, Hiroki Kinoshiro, Haruki Biomedical Engineering Mechanical Engineering Kogakuin University Tokyo163-8677 Japan Biomedical Engineering Department of Mechanical Engineering Kogakuin University Tokyo163-8677 Japan Biomedical Engineering Systems Design Kogakuin University Tokyo163-8677 Japan

ISBN: (纸本)9781950492657

The effect of the shear stress on deformation cycle has been investigated in vitro. To make a Couette type of shear flow, the culture medium fluid was sandwiched with a constant gap between parallel walls: a lower stationary culture disk, and an upper rotating disk. Mouse fat precursor cells (3T3-L1) were used in the test. After cultivation without flow for 24 hours for adhesion of cells on the lower plate, the shear stress τ (0.4 Pa Copyright 2022 © by the International Institute of Informatics and Systemics. All rights reserved.

关键词： Shear stress

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Bidirectional rotating direct-current triboelectric nanogenerator with self-adaptive mechanical switching for harvesting reciprocating motion

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International Journal of Extreme Manufacturing 2024年第4期6卷 324-335页

作者： Donghan Lee Joonmin Chae Sumin Cho Jong Woo Kim Awais Ahmad Mohammad Rezaul Karim Moonwoo La Sung Jea Park Dongwhi Choi Department of Mechanical Engineering(Integrated Engineering Program) Kyung Hee University1732 Deogyeong-daeroYonginGyeonggi 17104Republic of Korea Department of Chemistry University of LahoreLahorePakistan Department of Mechanical Engineering College of EngineeringKing Saud UniversityRiyadh 11421Saudi Arabia School of Mechanical Engineering Korea University of Technology and Education1600 Chungjeol-roCheonanChungnam 31253Republic of Korea

Amid the growing interest in triboelectric nanogenerators(TENGs)as novel energy-harvesting devices,several studies have focused on direct current(DC)TENGs to generate a stable DC output for operating electronic ***,owing to the working mechanisms of conventional DC TENGs,generating a stable DC output from reciprocating motion remains a ***,we propose a bidirectional rotating DC TENG(BiR-TENG),which can generate DC outputs,regardless of the direction of rotation,from reciprocating *** distinct design of the BiR-TENG enables the mechanical rectification of the alternating current output into a rotational-direction-dependent DC ***,it allows the conversion of the rotational-direction-dependent DC output into a unidirectional DC output by adapting the configurations depending on the rotational *** to these tailored design strategies and subsequent optimizations,the BiR-TENG could generate an effective unidirectional DC *** of the BiR-TENG for the reciprocating motions of swinging doors and waves were demonstrated by harnessing this *** study demonstrates the potential of the BiR-TENG design strategy as an effective and versatile solution for energy harvesting from reciprocating motions,highlighting the suitability of DC outputs as an energy source for electronic devices.

关键词： direct-current triboelectric nanogenerator mechanical rectification self-adaptive mechanical design harvesting reciprocation motion

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Automated segmentation of central airway obstruction from endoscopic video stream with deep learning

Automated segmentation of central airway obstruction from en...

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Medical Imaging 2025: Image-Guided Procedures, Robotic Interventions, and Modeling

作者： Li, Hao Wang, Jiacheng Kumar, Nithin d'Almeida, Jesse Lu, Daiwei Acar, Ayberk Han, John Yang, Qingyun Ertop, Tayfun Efe Wu, Jie Ying Webster, Robert J. Oguz, Ipek Department of Computer Science Vanderbilt University Nashville United States Department of Mechanical Engineering Vanderbilt University Nashville United States Department of Mechanical Aerospace and Biomedical Engineering University of Tennessee Knoxville United States

ISBN: (纸本)9781510685949

Central airway obstruction (CAO) can disrupt normal breathing and pose significant risks, with treatments often involving surgical removal. Accurate image segmentation is crucial for identifying the target region to assist surgeons or robotic surgery system during operations. Although manual annotation is the gold standard, it is time-consuming and subjective, making a robust automated segmentation algorithm desirable. In this paper, we propose an automated deep learning framework for CAO segmentation. As a benchmark study, we build a custom CAO phantom model and acquire endoscopy videos. We then establish inter-rater variability. To assess the effectiveness of the proposed method, a 4-fold cross-validation is performed with The Dice score as an evaluation metric. The proposed CAO segmentation method yields mean binary Dice scores of 0.95 and 0.89 against annotations from two human raters, respectively, compared to an inter-rater variability Dice score of 0.88. This indicates that the proposed framework can provide robust CAO segmentation from endoscopic video. © 2025 SPIE

关键词： Image segmentation

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Control engineering investigation of the effects of proliferative diabetic retinopathy on the crystalline lens and ciliary muscle dynamic behavior

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Research on biomedical engineering 2023年第3期39卷 663-676页

作者： Oliveira, Rebeca Hannah de M. Silva, Mayla dos S. Nunes, Gustavo A. M. A. Faria, Rafael Mendes Santos, Kleriston Silva Rosa, Leandro L. F. Rosa, Mário F. F. Rosa, Suélia de S. R. F. Department of Biomedical Engineering Johns Hopkins University School of Medicine BaltimoreMD United States Postgraduate Program in Mechatronic Systems University of Brasília DF Brasilia Brazil Optometry Clinic GO Goiânia Brazil Biomedical Engineering Graduate Program University of Brasília DF Brasilia Brazil University of Brasilia – UnB DF Brasilia Brazil

Purpose: Proliferative diabetic retinopathy (PDR) affects more than 100 million adults worldwide and is one of the primary diseases leading to blindness and affecting the eye’s retina. Few papers mention its impact on the anterior segment of the eye. Methods: We present a novel bond graph model of the human eye calibrated with data from the literature to simulate the effects of retinopathy on lens behavior. Through mathematical representation in state space and transfer functions, we simulate the dynamic responses of the physiological and pathological systems. Results: The dynamic response to impulse inputs shows a distinct peak amplitude (0.01 difference) and transient time (0.0001 s) for PDR and Healthy systems at Region B (lens and ciliary muscle). Qualitative increase in ocular vasculature aggravation attenuates PDR dynamic response to unitary step input compared to Healthy (50% decay at 20 days of simulation) at Region B. Conclusions: The model suggests the potential impact of PDR on ciliary muscle behavior, which can have a clinical translation on diagnosis, follow-up, and treatment of the disease. It can be used for future studies on the effects of retinopathy on different ocular regions. © 2023, The Author(s), under exclusive licence to The Brazilian Society of biomedical engineering.

关键词： Eye protection

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Improving Thyroid Disorder Diagnosis via Ensemble Stacking and Bidirectional Feature Selection

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Computers, Materials & Continua 2024年第3期78卷 4225-4241页

作者： Muhammad Armghan Latif Zohaib Mushtaq Saad Arif Sara Rehman Muhammad Farrukh Qureshi Nagwan Abdel Samee Maali Alabdulhafith Yeong Hyeon Gu Mohammed A.Al-masni Department of Computer and Information System Cleveland State UniversityOhio44115USA Department of Electrical Electronics and Computer SystemsCollege of Engineering and TechnologyUniversity of SargodhaSargodha40100Pakistan Department of Mechanical Engineering College of EngineeringKing Faisal UniversityAl-Ahsa31982Saudi Arabia Department of Biomedical Engineering Riphah International UniversityIslamabad44000Pakistan Department of Electrical Engineering Riphah International UniversityIslamabad44000Pakistan Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Artificial Intelligence College of Software and Convergence TechnologySejong UniversitySeoul05006Korea

Thyroid disorders represent a significant global health challenge with hypothyroidism and hyperthyroidism as two common conditions arising from dysfunction in the thyroid *** and timely diagnosis of these disorders is crucial for effective treatment and patient *** research introduces a comprehensive approach to improve the accuracy of thyroid disorder diagnosis through the integration of ensemble stacking and advanced feature selection *** forward feature selection,sequential backward feature elimination,and bidirectional feature elimination are investigated in this *** ensemble learning,random forest,adaptive boosting,and bagging classifiers are *** effectiveness of these techniques is evaluated using two different datasets obtained from the University of California Irvine-Machine Learning Repository,both of which undergo preprocessing steps,including outlier removal,addressing missing data,data cleansing,and feature *** experimentation demonstrates the remarkable success of proposed ensemble stacking and bidirectional feature elimination achieving 100%and 99.86%accuracy in identifying hyperthyroidism and hypothyroidism,*** enhancing detection accuracy,the ensemble stacking model also demonstrated a streamlined computational complexity which is pivotal for practical medical *** significantly outperformed existing studies with similar objectives underscoring the viability and effectiveness of the proposed *** research offers an innovative perspective and sets the platform for improved thyroid disorder diagnosis with broader implications for healthcare and patient well-being.

关键词： Ensemble learning random forests boosting dimensionality reduction machine learning smart healthcare computer aided diagnosis

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Regional Framework Towards Establishing Treatment, Storage, and Disposal (TSD) Facilities for PV Waste Management in the Philippines: A Case Study of Laguna Province

Regional Framework Towards Establishing Treatment, Storage, ...

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2024 Symposium on Insight to Foresight via Geospatial Technologies

作者： Diccion, Antonio L. Duran, Jeffrey Z. Engineering Program School of Advanced Studies Saint Louis University Baguio City2600 Philippines Mechanical and Mechatronics Engineering Department School of Engineering and Architecture Saint Louis University Baguio City2600 Philippines

The accelerated adoption of photovoltaic (PV) systems for renewable power generation in the Philippines will yield a tremendous amount of PV waste. However, the country lacks a comprehensive framework for understanding PV module waste volume growth and optimally siting Treatment, Storage, and Disposal (TSD) facilities for PV waste management based on minimum siting factor. The study aims to develop a regional framework that utilizes a geographic information system (GIS)-based approach to find the potential sites and optimal locations of TSD facilities in Laguna, Philippines, based on the estimated PV module waste growth of solar energy systems with service contracts and minimum siting criteria under department of Environment and Natural Resources (DENR) Administrative Order 2013-22. By 2060, the projected amount of PV module waste in Laguna province will be around 162,230 metric tons based on the waste projection results. The suitable sites cover around 19,720.5 hectares or 11.21% of the total land area of Laguna, which were determined by various siting factors that encompass social, economic, and environmental factors and obtained using binary suitability analysis and vector overlay analysis. The optimal locations of the two TSD facilities were identified using strategic positioning based on hotspot analysis, clustering algorithm, and proximity analysis. Consequently, the distance and GHG emissions of the two optimal locations were calculated. Indeed, the approach will serve as a guide for policymakers and other stakeholders in understanding PV module waste growth and strategically and optimally position TSD facilities on suitable sites for efficient and effective PV waste management. © Author(s) 2024.

关键词： Waste treatment

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Hysteresis Effect of Tangential Force Field on Cell Deformation on Micro-striped Topography: Behavior of Cell Migrating between Different Pattern Compartments 13

Hysteresis Effect of Tangential Force Field on Cell Deformat...

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13th International Multi-Conference on Complexity, Informatics and Cybernetics, IMCIC 2022

作者： Hashimoto, Shigehiro Sekine, Wataru Yonezawa, Hiroki Endo, Yuji Biomedical Engineering Department of Mechanical Engineering Kogakuin University Tokyo163-8677 Japan Biomedical Engineering Systems Design Kogakuin University Tokyo163-8677 Japan Biomedical Engineering Mechanical Engineering Kogakuin University Tokyo163-8677 Japan

ISBN: (纸本)9781950492619

The hysteresis effect of tangential force field on deformation of a cell has been studied in relation to the behavior of the cell migrating to different topography pattern compartments in vitro. The stripe-pattern ridges (0.7 μm height, 3 μm width, and 3 μm interval) was made on the surface of the scaffold plate. Variation was made on the angle between the longitudinal direction of the ridge and the direction of the tangential force by centrifuge: 0 degrees, 45 degrees, and 90 degrees. Myoblast (C2C12: mouse myoblast cell line) was used in the experiment. After the centrifugation of 50 G for 5 hours, the two-dimensional projected area (S) of each cell has been tracked by the time-lapse microscope images for 48 hours. The experimental results show that the cell area S tended to shrink and stabilize as a cell migrated into the striped compartment of surface topography parallel to the tangential force field. The variation in the cell area S was greater in the surface topography compartment with the diagonal stripes with respect to the tangential force field. These reactions of the cells remained for 30 hours after the stimulation was stopped. © by the International Institute of Informatics and Systemics.

关键词： Cell culture

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Effect of Anthropometry on Plantar Pressure Distribution during Gait in Overweight Male Subjects 46

Effect of Anthropometry on Plantar Pressure Distribution dur...

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46th Annual International Conference of the IEEE engineering in Medicine and Biology Society, EMBC 2024

作者： Alkhalaileh, Abdelsalam Tareq Abdullah, Muhammed Hulleck, Abdul Aziz Khalaf, Kinda Jelinek, Herbert F. El Rich, Marwan Khalifa University Department of Mechanical Engineering Abu Dhabi United Arab Emirates Khalifa University Health Care Engineering and Innovation Center Department of Biomedical Engineering Abu Dhabi United Arab Emirates Khalifa University Department of Medical Sciences Biotechnology Center Abu Dhabi United Arab Emirates Khalifa University Health Care Engineering and Innovation Center Department of Mechanical Engineering Abu Dhabi United Arab Emirates

ISBN: (纸本)9798350371499

Traditionally, research on plantar pressure in overweight/obese populations has predominantly focused on dividing the plantar surface into two or three regions, considering factors such as body mass index (BMI), age, and gender. This study took a more comprehensive approach, incorporating various anthropometric measurements representing body shape, including arm, leg, and shoulder lengths, as well as thigh, chest, waist, hip, and ankle circumferences. Utilizing retrospective data from overweight but healthy male subjects, the study yielded results revealing robust correlations with Euclidean measurements, circumferential measurements, and circumferential ratios. Interestingly, while no significant correlations were found between peak plantar pressure magnitude and location with BMI, significant correlations were seen with lower arm length (-0.73), shoulder length (0.69), ankle circumference (0.69), thigh circumference (0.66 and 0.68). Incorporating ratios that combined multiple measurements showed promise, with correlation coefficients exceeding 0.7. These findings suggest that a comprehensive plantar pressure analysis should not solely rely on BMI but rather include a thorough examination of subject anthropometry. The results also shed light on the feasibility of developing an index for predicting plantar pressure characteristics based on anthropometric data. Further research and expanded datasets are crucial for refining and validating these findings. © 2024 IEEE.

关键词： Anthropometry

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Synthesis of amorphous silica from rice husk ash using the sol–gel method: Effect of alkaline and alkaline concentration

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Materials Today: Proceedings 2023年 87卷 225-229页

作者： Aprilia S. Rosnelly C.M. Zuhra Fitriani F. Haffiz Akbar E. Raqib M. Rahmah K. Amin A. Baity R.A. Department of Chemical Engineering Engineering Faculty Universitas Syiah Kuala Banda Aceh 23111 Indonesia Doctoral Program School of Engineering Post Graduate Program Universitas Syiah Kuala Banda Aceh 23111 Indonesia Mechanical Engineering Department Engineering Faculty University of Abulyatama Lampoh Keude-Aceh Besar Indonesia

In this study, silica extraction from RHA (rice husk ash) has been successfully performed by alkaline using KOH and NaOH with sol–gel precipitation. The silica gel was characterized for the functional group by FTIR, crystallinity with XRD, structure silica with SEM and particle size with PSA. The results show the higher concentration of solvent led to higher silica. The FTIR analysis revealed vibrations of Si[sbnd]O and Si[sbnd]O[sbnd]Si on the product. Additionally, observed to be amorphous and aggregated, the silica extracted from RHA also exhibited a decrease in all samples. © 2023

关键词： Alkaline extraction Concentration of solvent Potassium hydroxide Rice husk ash Silica Sodium hydroxide

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