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Gas marbles: ultra-long-lasting and ultra-robust bubbles formed by particle stabilization

Frontiers of Chemical Science and engineering 2022年第11期16卷 1681-1687页

作者： Xuxin Zhao Kunling Yang Zhou Liu Ho Cheung Shum Tiantian Kong College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen 518000China Department of Mechanical Engineering University of Hong KongHong KongChina Advanced Biomedical Instrumentation Centre Hong KongChina Department of Biomedical Engineering School of MedicineShenzhen UniversityShenzhen 518000China Department of Urology The Institute of Translational MedicineThe First Affiliated Hospital of Shenzhen UniversityShenzhen Second People’s HospitalShenzhen 518000China

Bubbles and foams are ubiquitous in daily life and industrial *** their dynamic behaviors is of key importance for foam manufacturing processes in food packaging,cosmetics and *** bubbles are inherently fragile and transient;enhancing their robustness and shelf lives is an ongoing *** rupture can be attributed to liquid evaporation,thin film drainage and the nuclei of environmental *** by particle-stabilized interfaces in Pickering emulsions,armored bubbles and liquid marble,bubbles are protected by an enclosed particle-entrapping liquid thin film,and the resultant soft object is termed gas *** gas marble exhibits mechanical strength orders of magnitude higher than that of soap bubbles when subjected to overpressure and underpressure,owing to the compact particle monolayer straddling the surface liquid *** using a water-absorbent glycerol solution,the resulting gas marble can persist for 465 d in normal atmospheric *** particle-stabilizing approach not only has practical implications for foam manufacturing processes but also can inspire the new design and fabrication of functional biomaterials and biomedicines.

关键词： bubble particles interfaces armored bubble liquid marble gas marble Pickering emulsion

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All-Textile Pressure Sensitive Sock for Mobile Health Applications

All-Textile Pressure Sensitive Sock for Mobile Health Applic...

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2024 International Conference on the Challenges, Opportunities, Innovations and Applications in Electronic Textiles, E-Textiles 2024

作者： Galli, Valeria Kohler, Tobias Menon, Carlo ETH Zurich Biomedical and Mobile Health Technology Group Department of Health Sciences and Technology Zurich Switzerland ETH Zurich Biomedical and Mobile Health Technology group Department of Health Sciences and Technology Department of Mechanical and Process Engineering Zurich Switzerland

ISBN: (纸本)9783000804298

Monitoring plantar pressure continuously is relevant in different applications, e.g., in gait monitoring, foot ulcer prevention, and more. Current solutions include pressure sensitive insoles that are expensive and cannot fully conform to the feet or shoes surface (e.g., in orthotics for diabetic patients). We propose a soft and flexible smart sock to monitor pressure continuously and unobtrusively. The sock features eight textile-based capacitive pressure sensors on the load-bearing areas of the foot. Electromechanical characterization showed suitability of the sensors for the intended application (high pressure up to 500 kPa). Preliminary tests on a healthy participant walking with the sock showed good agreement with commercial smart insoles. This is the first example of a fully textile smart sock with more than four capacitive pressure sensors for in-shoe plantar pressure measurement. The presented prototype shows potential as an inexpensive and comfortable solution for day-to-day monitoring of plantar pressure across various applications. © 2024 Fraunhofer IZM.

关键词： Smart textiles

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Development of paper-based rna amplification devices for point-of-care detection of hiv

Development of paper-based rna amplification devices for poi...

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ASME 2023 International mechanical engineering Congress and Exposition, IMECE 2023

作者： Adedokun, George Sidhu, Gurjit Wang, Gary P. Hugh Fan, Z. Department of Mechanical and Aerospace Engineering United States Department of Medicine United States Purrit Family Department of Biomedical Engineering University of Florida PO Box 116250 GainesvilleFL32611 United States

ISBN: (纸本)9780791887622

Point-of-care (POC) testing of human immunodeficiency virus (HIV) infection is challenging in resource-limited settings, where conventional nucleic acid tests are costly and complex. Paper-based devices offer a low-cost, simple, and rapid alternative, but most of them rely on antibody or antigen detection, which have limitations in sensitivity and specificity. In this work, we develop and evaluate a miniaturized platform for the detection of HIV infection in resource-limited settings. The platform uses low-cost and environment-friendly paper for sample preparation as a nucleic-Acid-extraction substrate followed by isothermal amplification in a battery-powered coffee mug and colorimetric detection. Our platform can detect HIV in human serum and plasma samples with high sensitivity and specificity. We demonstrate the feasibility and performance of our platform using clinical samples and compare it with conventional nucleic acid tests. © 2023 American Society of mechanical Engineers (ASME). All rights reserved.

关键词： Biomolecules

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Comparison of Hemodynamic Circulation in Pulsatile and Nonpulsatile Extracorporeal Membrane Oxygenation Systems Using an In-Vitro Heart Model

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ASAIO Journal 2025年 2025 Apr 17页

作者： Yoo, Changyoung Jang, Hyun-Woo Kang, Seongmin Choi, Seong-Wook Interdisciplinary Program in Biohealth-Machinery Convergence Engineering Kangwon National University Chuncheon-si Korea Republic of Program of Mechanical and Biomedical Engineering College of Engineering Kangwon National University Chuncheon-si Korea Republic of

This study conducts an in-vitro experiment using a mock circulation system that mimics human circulation to assess the veno-arterial extracorporeal membrane oxygenation (ECMO) system. This study aims to compare the hemodynamic effects of centrifugal and pulsatile ECMO systems on the body using an in-vitro cardiogenic shock model. The heart model used in this study involves a contracting blood sac with inlet and outlet valves, capable of maintaining arterial pressure between 80 and 120 mm Hg while delivering a blood flow of 1.8-2 L/min, effectively replicating a cardiogenic shock model. The contraction force in the heart model was generated using a pneumatic cylinder and gradually decreased to simulate reduced cardiac function. The initial blood flow rates of both ECMO systems were maintained at 2 L/min under identical conditions for a fair comparison. Upon reducing the stroke volume of the heart to 35 ml, the ECMO system with counter-pulsation control increased the cardiac output by 10.7% and systemic circulation by 3.8% compared with the conventional ECMO system. This study demonstrates the hemodynamic benefits provided by the sustained counter-pulsation in an in-vitro weakened heart model. Pulsatile flow ECMO systems may serve as an alternative to address the limitations of continuous flow ECMO systems. © ASAIO 2025.

关键词： Heart

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A novel label-free electrochemical immunosensor for the detection of heat shock protein 70 of lung adenocarcinoma cell line following paclitaxel treatment using l-cysteine-functionalized Au@MnO2/MoO3 nanocomposites

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RSC Advances 2023年第43期13卷 29847-29861页

作者： Chen, Yi-An Shie, Ming-You Ho, Chia-Che Ye, Sheng-Wen Chen, I.-Wen Peter Shih, Yu-Yin Shen, Yu-Fang Chen, Yi-Wen x-Dimension Center for Medical Research and Translation China Medical University Hospital Taichung City404332 Taiwan The Master Program for Biomedical Engineering China Medical University Taichung City406040 Taiwan Department of Biomedical Engineering China Medical University Taichung City40447 Taiwan Department of Bioinformatics and Medical Engineering Asia University Taichung City41354 Taiwan Department of Chemistry National Cheng Kung University Tainan70101 Taiwan Graduate Institute of Biomedical Sciences China Medical University Taichung City40447 Taiwan

The future trend in achieving precision medicine involves the development of non-invasive cancer biomarker sensors that offer high accuracy, low cost, and time-saving benefits for risk clarification, early detection, disease detection, and therapeutic monitoring. A facile approach for the synthesis of MoO3 nanosheets was developed by thermally oxidizing MoS2 nanosheets in air followed by thermal annealing. Subsequently, Au@MnO2 nanocomposites were prepared using a combined hydrothermal process and in situ chemical synthesis. In this study, we present a novel immunosensor design strategy involving the immobilization of antiHSP70 antibodies on Au@MnO2/MoO3 nanocomposites modified on a screen-printed electrode (SPE) using EDC/NHS chemistry. This study establishes HSP70 as a potential biomarker for monitoring therapeutic response during anticancer therapy. Impedance measurements of HSP70 on the Au@MnO2/MoO3/SPE immunosensor using EIS showed an increase in impedance with an increase in HSP70 concentration. The electrochemical immunosensor demonstrated a good linear response in the range of 0.001 to 1000 ng mL−1 with a detection limit of 0.17 pg mL−1 under optimal conditions. Moreover, the immunosensor was effective in detecting HSP70 at low concentrations in a lung adenocarcinoma cell line following Paclitaxel treatment, indicating its potential for early detection of the HSP70 biomarker in organ-on-a-chip and clinical applications. © 2023 The Royal Society of Chemistry.

关键词： Nanosheets

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Removal of As(V)in the presence of Cr(VI)in contaminated water from the Bajio region of Mexico using ferrihydrite-functionalized graphene oxide(GOFH):A case study

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Emerging Contaminants 2024年第3期10卷 134-144页

作者： D.R.Joya-Cardenas J.P.Rodríguez-Caicedo M.A.Corona-Rivera N.Saldana-Robles C.E.Damian-Ascencio A.Saldana-Robles Graduate Program in Biosciences University of GuanajuatoIrapuato36500Mexico Facultad de Ingenierías y Tecnologías Instituto XeriraUniversidad de SantanderBucaramanga680003Colombia Chemical Engineering Unit Academic Multidisciplinary Region Altiplano UAMRA.Autonomous University of San Luis PotosíMatehualaSan Luis Potosí78000Mexico Department of Agricultural Engineering University of GuanajuatoIrapuato36500Mexico Department of Mechanical Engineering University of GuanajuatoSalamanca36800Mexico Mechanical Engineering Department Virginia TechBlacksburgVA24061USA

The presence of heavy metals such as arsenic(As)and chromium(Cr)can be considered one of the most toxic heavy *** study aims to develop and evaluate a graphene oxide(GO)based material functionalized with ferrihydrite for the removal of As(V)in the presence of Cr(VI).The adsorbent ferrihydrite-functionalized graphene oxide(GOFH)was characterized by SEM,FTIR,XRD,XPS,surface charge,BET and *** adsorption capacities for As(V)and Cr(VI)were 160 and 66 mg g^(-1)respectively at pH 4 and 298 K,fitting the Langmuir *** binary systems,GOFH adsorbed As(V)with an adsorption capacity of 137 mg g^(-1)in the presence of 20 mg L^(-1)Cr(VI)at room *** analysis revealed an exothermic and spontaneous ***,GOFH effectively removed several coexisting anions from groundwater,including SO_(4)^(2-),CO_(3)^(2-)and Cl^(-).This work evidences the potential of GOFH for competitive adsorption of priority pollutants from complex *** GOFH material represents a technically and economically viable technology for application in groundwater decontamination,as it requires inexpensive precursors and ambient conditions during synthesis and operation.

关键词： Competition Ions Contamination Groundwater Adsorption capacity

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Plasma-Enabled Graphene Quantum Dot Hydrogel-Magnesium Composites as Bioactive Scaffolds for In Vivo Bone Defect Repair

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ACS Applied Materials and Interfaces 2023年第38期15卷 44607-44620页

作者： Wong, Pei-Chun Kurniawan, Darwin Wu, Jia-Lin Wang, Wei-Ru Chen, Kuan-Hao Chen, Chieh-Ying Chen, Ying-Chun Veeramuthu, Loganathan Kuo, Chi-Ching Ostrikov, Kostya Ken Chiang, Wei-Hung Graduate Institute of Biomedical Optomechatronics College of Biomedical Engineering Taipei Medical University Taipei110 Taiwan Orthopedics Research Center Taipei Medical University Hospital Taipei110 Taiwan Department of Chemical Engineering National Taiwan University of Science and Technology Taipei10607 Taiwan Department of Orthopedics School of Medicine College of Medicine Taipei Medical University Taipei110 Taiwan Department of Orthopedics Taipei Medical University Hospital Taipei110 Taiwan Centers for Regional Anesthesia and Pain Medicine Wan Fang Hospital Taipei Medical University Taipei110 Taiwan School of Biomedical Engineering College of Biomedical Engineering Taipei Medical University Taipei110 Taiwan Graduate Institute of Biomedical Materials and Tissue Engineering College of Biomedical Engineering Taipei Medical University Taipei110 Taiwan Department of Orthopedics Shuang Ho Hospital Taipei Medical University New Taipei235 Taiwan Department of Mechanical Engineering National Taiwan University of Science and Technology Taipei10607 Taiwan Department of Molecular Science and Engineering Institute of Organic and Polymeric Materials National Taipei University of Technology Taipei106 Taiwan BrisbaneQLD4000 Australia

Bioactive and mechanically stable metal-based scaffolds are commonly used for bone defect repair. However, conventional metal-based scaffolds induce nonuniform cell growth, limiting damaged tissue restoration. Here, we develop a plasma nanotechnology-enhanced graphene quantum dot (GQD) hydrogel-magnesium (Mg) composite scaffold for functional bone defect repair by integrating a bioresource-derived nitrogen-doped GQD (NGQD) hydrogel into the Mg ZK60 alloy. Each scaffold component brings major synergistic advantages over the current alloy-based state of the art, including (1) mechanical support of the cortical bone and calcium deposition by the released Mg2+ during degradation;(2) enhanced uptake, migration, and distribution of osteoblasts by the porous hydrogel;and (3) improved osteoblast adhesion and proliferation, osteogenesis, and mineralization by the NGQDs in the hydrogel. Through an in vivo study, the hybrid scaffold with the much enhanced osteogenic ability induced by the above synergy promotes a more rapid, uniform, and directional bone growth across the hydrogel channel, compared with the control Mg-based scaffold. This work provides insights into the design of multifunctional hybrid scaffolds, which can be applied in other areas well beyond the demonstrated bone defect repair. © 2023 American Chemical Society.

关键词： Semiconductor quantum dots

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Degradation of Tattoo Inks by Cold Atmospheric Plasma Treatment: A Proof-of-Concept Study

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Plasma Medicine 2022年第3期12卷 1-21页

作者： Çukur, Elif Ercan, Utku Kürşat Department of Biomedical Engineering School of Engineering and Architecture İzmir Katip Çelebi University Çiğli İzmir35620 Turkey Isparta University of Applied Sciences Uluborlu Vocational School Biomedical Device Technologies Program Isparta32200 Turkey

Tattoos have been a part of the culture and a way of expression for a remarkable portion of society throughout history. However, different dissatisfactions related to tattoos lead people to tattoo removal procedures that can be carried out in various ways. Among them, laser tattoo removal is the most common technique. However, laser tattoo removal could have downsides;thus, novel technologies that either support or replace conventional methods are needed. In the present study, the degradation of red, yellow, green, blue, black and white tattoo inks by plasma treatment was evaluated for possible future use of cold plasma in tattoo removal. Tattoo inks were treated with DBD air plasma in the aqueous form and in the agarose gel. Furthermore, also tattoo pigments were exposed to plasma-treated water. The KI-starch reagent was used to correlate the oxidative strength of plasma-treated water with the degradation of tattoo inks. Degradation of tattoo inks was determined by reflectance measurements and was measured as color change with respect to plasma treatment time. Color changes of tattoo inks were represented using the CIELAB color system and CIE xyY color space. Our results suggest that air DBD plasma treatment and plasma-treated water are capable of degrading tattoo inks. The color change of tattoo inks due to degradation by plasma was clearly distinguishable by the naked eye, and the maximum value corresponding to color change was measured for red tattoo ink. © 2022 by Begell House, Inc.

关键词： Color

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Tracking Markers on Scaffold Associated with Movement of Cultured Myotubes 26

Tracking Markers on Scaffold Associated with Movement of Cul...

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26th World Multi-Conference on Systemics, Cybernetics and Informatics, WMSCI 2022

作者： Endo, Yoshiaki Hashimoto, Shigehiro Sakai, Shusei Shimayama, Tomoki Biomedical Engineering Systems Design Kogakuin University Tokyo163-8677 Japan Biomedical Engineering Department of Mechanical Engineering Kogakuin University Tokyo163-8677 Japan

ISBN: (纸本)9781950492657

The movement of micro matrix pattern markers on the rear side of the scaffold thin film has been tracked associated with the movement of the layer of myotubes under the cyclic electric pulse stimulation in vitro. The scaffold was made of a thin polydimethylsiloxane film (thickness of 6 µm), of which the back side had arrangement of micro-protrusions (4 µm diameter, 2 µm height, interval 30 µm) made by the photolithography technique. Mouse myoblasts (C2C12) were cultured to be differentiated into myotubes on the scaffold for 10 days. Markers on the film could be observed under a microscope, although the contrast of markers was not sufficient to be automatically distinguished from the pattern of myotubes. The experimental results show that the local cyclic movement of the markers was able to be measured. The designed scaffold has a potential to analyze the local contractile movement of the layer of myotubes in vitro. The technology can be applied to functional evaluation of engineered tissue. Copyright 2022 © by the International Institute of Informatics and Systemics. All rights reserved.

关键词： Cell culture

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Inverse Origami Design Model for Soft Robotic Development

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Soft Robotics 2024年第1期11卷 131-139页

作者： Hu, Qiqiang Li, Junyang Tao, Jian Dong, Erbao Sun, Dong Department of Biomedical Engineering City University of Hong Kong Hong Kong Department of Precision Machinery and Precision Instrumentation University of Science and Technology of China Hefei China Department of Electronic Engineering Ocean University of China Qingdao China CAS Key Laboratory of Mechanical Behavior and Design of Materials School of Engineering Science University of Science and Technology of China Hefei China Centre for Robotics and Automation Shenzhen Research Institute of City University of Hong Kong Shenzhen China

Origami provides an opportunity to construct a wide range of 3D functional structures by folding a flat sheet. It can be used to develop various soft functional robots by combining soft smart actuators. However, a simple and an effective model that can address the challenging problem of designing origami patterns to connect origami design with robotics is lacking, thereby greatly increasing the threshold of soft origami robots and hindering its development. This study proposes an easy-to-use inverse origami design model to generate the flat crease pattern from the desired folded shape automatically while simulating origami morphing by simply providing the shape parameters or 2D shape graphics. This method overcomes the difficulty of origami design and enables a close connection between origami and robotics. Through this method, various soft origami robots can be developed with low design complexity and time cost to achieve different functions, thereby promoting the development of soft origami robots. © 2024 Mary Ann Liebert Inc.. All rights reserved.

关键词： Robots

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