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Author Correction: A recellularized human colon model identifies cancer driver genes

Nature biotechnology 2019年第7期37卷 820页

作者： Huanhuan Joyce Chen Zhubo Wei Jian Sun Asmita Bhattacharya David J Savage Rita Serda Yuri Mackeyev Steven A Curley Pengcheng Bu Lihua Wang Shuibing Chen Leona Cohen-Gould Emina Huang Xiling Shen Steven M Lipkin Neal G Copeland Nancy A Jenkins Michael L Shuler Department of Biomedical Engineering Cornell University Ithaca New York USA. Cancer Research Program Houston Methodist Research Institute Houston Texas USA. Department of Medicine Weill Cornell Medical College New York New York USA. Department of Genetic Medicine Weill Cornell Medical College New York New York USA. Genetics Genomics and Development Cornell University Ithaca New York USA. University of Texas Medical School at Houston Houston Texas USA. Department of Chemistry Rice University Houston Texas USA. Department of Surgery Baylor College of Medicine Houston Texas USA. Department of Biological and Environmental Engineering Cornell University Ithaca New York USA. Chemical Biology in Surgery Weill Cornell Medical College New York New York USA. Department of Biochemistry Weill Cornell Medical College New York New York USA. Department of Stem Cell Biology and Regenerative Medicine Cleveland Clinic Cleveland Ohio USA. Department of Colorectal Surgery Cleveland Clinic Cleveland Ohio USA. Cancer Research Program Houston Methodist Research Institute Houston Texas USA. njenkins2@***. Department of Biomedical Engineering Cornell University Ithaca New York USA. mls50@cornell.edu.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Hearing loss prevalence and years lived with disability, 1990-2019: Findings from the Global Burden of Disease Study 2019

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The Lancet 2021年第10278期397卷 996-1009页

作者： Haile, Lydia M. Kamenov, Kaloyan Briant, Paul Svitil Orji, Aislyn U. Steinmetz, Jaimie D. Abdoli, Amir Abdollahi, Mohammad Abu-Gharbieh, Eman Afshin, Ashkan Ahmed, Haroon Rashid, Tarik Ahmed Akalu, Yonas Alahdab, Fares Alanezi, Fahad Mashhour Alanzi, Turki M. Al Hamad, Hanadi Ali, Liaqat Alipour, Vahid Al-Raddadi, Rajaa M. Amu, Hubert Arabloo, Jalal Arab-Zozani, Morteza Arulappan, Judie Ashbaugh, Charlie Atnafu, Desta Debalkie Babar, Zaheer-Ud-Din Baig, Atif Amin Banik, Palash Chandra Bärnighausen, Till Winfried Barrow, Amadou Bender, Rose G. Bhagavathula, Akshaya Srikanth Bhardwaj, Nikha Bhardwaj, Pankaj Bibi, Sadia Bijani, Ali Burkart, Katrin Cederroth, Christopher R. Charan, Jaykaran Choudhari, Sonali Gajanan Chu, Dinh-Toi Couto, Rosa A.S. Dagnew, Amare Belachew Dagnew, Baye Dahlawi, Saad M.A. Dai, Xiaochen Dandona, Lalit Dandona, Rakhi Desalew, Assefa Dhamnetiya, Deepak Dhimal, Mandira Lamichhane Dhimal, Meghnath Doyle, Kerrie E. Duncan, Bruce B. Ekholuenetale, Michael Filip, Irina Fischer, Florian Franklin, Richard Charles Gaidhane, Abhay Motiramji Gaidhane, Shilpa Gallus, Silvano Ghamari, Farhad Ghashghaee, Ahmad Ghozali, Ghozali Gilani, Syed Amir Glǎvan, Ionela-Roxana Golechha, Mahaveer Goulart, Barbara Niegia Garcia Gupta, Veer Bala Gupta, Vivek Kumar Hamidi, Samer Hammond, Billy Randall Hay, Simon I. Hayat, Khezar Heidari, Golnaz Hoffman, Howard J. Hopf, Kathleen Pillsbury Hosseinzadeh, Mehdi Househ, Mowafa Hussain, Rabia Hwang, Bing-Fang Iavicoli, Ivo Ibitoye, Segun Emmanuel Ilesanmi, Olayinka Stephen Irvani, Seyed Sina Naghibi Islam, Sheikh Mohammed Shariful Iwagami, Masao Jacob, Louis Jayapal, Sathish Kumar Jha, Ravi Prakash Jonas, Jost B. Kalhor, Rohollah Al-Salihi, Nawzad Kameran Kandel, Himal Kasa, Ayele Semachew Kayode, Gbenga A. Khalilov, Rovshan Khan, Ejaz Ahmad Khatib, Mahalaqua Nazli Kosen, Soewarta Koyanagi, Ai Kumar, G. Anil Landires, Ivan Lasrado, Savita Lim, Stephen S. Liu, Xuefeng Lobo, Stany W. Lugo, Alessandra Makki, Alaa Mendoza, Walter Mersha, Amanual Getnet Mihretie, Kebadnew Mulatu Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Noncommunicable Diseases World Health Organization (WHO) Geneva Switzerland Department of Parasitology and Mycology Jahrom University of Medical Sciences Jahrom Iran The Institute of Pharmaceutical Sciences (TIPS) Tehran University of Medical Sciences Tehran Iran School of Pharmacy Tehran University of Medical Sciences Tehran Iran Clinical Sciences Department University of Sharjah Sharjah United Arab Emirates Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Department of Biosciences COMSATS Institute of Information Technology Islamabad Pakistan Department of Computer Science and Engineering University of Kurdistan Hewler Erbil Iraq Department of Medical Physiology University of Gondar Gondar Ethiopia Mayo Evidence-based Practice Center Mayo Clinic Foundation for Medical Education and Research Rochester MN United States Imam Abdulrahman Bin Faisal University Dammam Saudi Arabia Health Information Management and Technology Department Dammam Saudi Arabia Geriatric and Long Term Care Department Hamad Medical Corporation Doha Qatar Rumailah Hospital Hamad Medical Corporation Doha Qatar Department of Biological Sciences National University of Medical Sciences (NUMS) Rawalpindi Pakistan Health Management and Economics Research Center Tehran Iran Department of Community Medicine King Abdulaziz University Jeddah Saudi Arabia Department of Population and Behavioural Sciences University of Health and Allied Sciences Ho Ghana Social Determinants of Health Research Center Birjand University of Medical Sciences Birjand Iran Department of Maternal and Child Health Sultan Qaboos University Muscat Oman Department of Health System and Health Economics Bahir Dar University Bahir Dar Ethiopia Department of Pharmacy University of Huddersfield Huddersfield United Kingdom Unit of Biochemistry Universiti

Background: Hearing loss affects access to spoken language, which can affect cognition and development, and can negatively affect social wellbeing. We present updated estimates from the Global Burden of Disease (GBD) study on the prevalence of hearing loss in 2019, as well as the condition's associated disability. Methods: We did systematic reviews of population-representative surveys on hearing loss prevalence from 1990 to 2019. We fitted nested meta-regression models for severity-specific prevalence, accounting for hearing aid coverage, cause, and the presence of tinnitus. We also forecasted the prevalence of hearing loss until 2050. Findings: An estimated 1·57 billion (95% uncertainty interval 1·51–1·64) people globally had hearing loss in 2019, accounting for one in five people (20·3% [19·5–21·1]). Of these, 403·3 million (357·3–449·5) people had hearing loss that was moderate or higher in severity after adjusting for hearing aid use, and 430·4 million (381·7–479·6) without adjustment. The largest number of people with moderate-to-complete hearing loss resided in the Western Pacific region (127·1 million people [112·3–142·6]). Of all people with a hearing impairment, 62·1% (60·2–63·9) were older than 50 years. The Healthcare Access and Quality (HAQ) Index explained 65·8% of the variation in national age-standardised rates of years lived with disability, because countries with a low HAQ Index had higher rates of years lived with disability. By 2050, a projected 2·45 billion (2·35–2·56) people will have hearing loss, a 56·1% (47·3–65·2) increase from 2019, despite stable age-standardised prevalence. Interpretation: As populations age, the number of people with hearing loss will increase. Interventions such as childhood screening, hearing aids, effective management of otitis media and meningitis, and cochlear implants have the potential to ameliorate this burden. Because the burden of moderate-to-complete hearing loss is concentrated in countries with low health-ca

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Selection of propolis Tetragonula sp. extract solvent with flavonoids and polyphenols concentration and antioxidant activity parameters

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AIP Conference Proceedings 2018年第1期1933卷

作者： Daisy Christina Heri Hermansyah Anondho Wijanarko Etin Rohmatin Muhamad Sahlan Diah Kartika Pratami Abdul Mun’im 1Departement of Chemical Engineering University of Indonesia Depok 16425 Indonesia 2Midwifery Department of Health Polytechnic Republic of Indonesia’s Health Ministry Tasikmalaya Indonesia 3Research Center for Biomedical Engineering (RCBE) Universitas Indonesia Kampus Baru UI Depok 16425 Indonesia 4Graduate Program of Pharmaceutical Sciences Faculty of Pharmacy University of Indonesia Depok 16425 Indonesia 5Department of Pharmacognosy-Phytochemistry Faculty of Pharmacy University of Indonesia Depok 16425 Indonesia

Antioxidants are inhibitory compounds that can inhibit auto oxidation reaction by binding to free radicals and highly reactive molecules. The human body needs antioxidant. Antioxidants can be obtained from a variety of natural ingredients, including propolis. Propolis is the natural sap of the bees, obtained from the herbs around the honeycomb. Ethanol is the solvent that often used to extract propolis. Although it has many advantages, ethanol also has weaknesses such as intolerance to alcohol by some people. Therefore, this research was to extract propolis Tetragonula sp. coarse (C) and soft (S) using four varieties of organic solvent, i.e. olive oil (OO), virgin coconut oil (VCO), propylene glycol (PG), and lecithin (L). It was expected to get the best solvent in extracting propolis. The selection of the best solvent was determined by total flavonoids and polyphenols content assay and antioxidant activity. At each test, the absorbance value read by a microplate reader. Flavonoids content assay is using AlCl3 method with best result on rough-VCO propolis extract of 2509,767 ± 615,02 µg/mL. Polyphenols content assay was using Folin Ciocalteu method with the best results on soft-VCO propolis extract of 1391 ± 171.47 µg/mL. Antioxidant activity assay is using DPPH method with best result on soft-VCO propolis extract with IC50 value of 1,559 ± 0,222 µg/mL.

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Conformational transitions of thai silk fibroin secondary structures

Conformational transitions of thai silk fibroin secondary st...

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biomedical engineering International Conference (BMEiCON)

作者： Supawich Chankow Somchai Luemunkong Sorada Kanokpanont Multidisciplinary in Biomedical Engineering Program Chulalongkorn University Bangkok Thailand Queen Sirikit Sericulture Center (Sisaket) Sisaket Thailand Department of Chemical Engineering Chulalongkorn University Bangkok Thailand

ISBN: (纸本)9781509039418

Secondary structures of silk fibroin (SF) related directly to their gelling, degradability, mechanical properties which affects its applications. The current works investigated the changes of Thai SF's secondary structure during the process of film fabrication. Thai SF from domestic silk cocoons, Bombyx mori (Nangnoi Sisaket 1) were dissolved into water soluble protein using two solvent systems, 9.3 M LiBr solution, and Ajisawa's reagent (CaCl 2 :water:EtOH at 1: 8: 2 by mole). The SF solution was subjected to liquid nitrogen followed by lyophilization to preserve the protein's structure. Films were casted from the SF solutions and were immersed in ethanol to regenerate the protein's original conformations. Attenuated totally reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) was used to quantify relative contents of protein's secondary structures altered by each step of the processes. Degummed silk fibers had the highest beta sheet crystallinity of 59.1%. Random coils and beta sheet structures of the SF prepared with Ajisawa's reagent were at 41.5% and 18.2%, and those prepared with LiBr solution were at 45.8% and 14.4%, respectively. The non-treated SF films consisted of 33.8-35.0% and 23.2-25.9% of beta sheets and random coils, respectively, despite of their preparation processes. Regeneration of the SF using ethanol immersion increased the beta sheet contents by 10-12% compared to the non-treated ones. Relative contents of beta turn, alpha helix, and tyrosine side chains were unchanged. The EtOH-regenerated Thai SF films contained 11-17% lower in beta sheet structures than the native fiber, suggesting the silk II formation was partially regained.

关键词： Films Coils Proteins Ethanol Solvents Fabrication Protein engineering

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Low‐Dimensional Organic Tin Bromide Perovskites and Their Photoinduced Structural Transformation

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Angewandte Chemie 2017年第31期129卷

作者： Chenkun Zhou Yu Tian Mingchao Wang Alyssa Rose Tiglet Besara Nicholas K. Doyle Zhao Yuan Jamie C. Wang Ronald Clark Yanyan Hu Theo Siegrist Shangchao Lin Biwu Ma Department of Chemical and Biomedical Engineering FAMU-FSU College of Engineering USA Materials Science and Engineering Program Florida State University USA Department of Mechanical Engineering FAMU-FSU College of Engineering USA Department of Chemistry and Biochemistry Florida State University USA National High Magnetic Field Laboratory Florida State University USA

Hybrid organic–inorganic metal halide perovskites possess exceptional structural tunability, with three‐ (3D), two‐ (2D), one‐ (1D), and zero‐dimensional (0D) structures on the molecular level all possible. While remarkable progress has been realized in perovskite research in recent years, the focus has been mainly on 3D and 2D structures, with 1D and 0D structures significantly underexplored. The synthesis and characterization of a series of low‐dimensional organic tin bromide perovskites with 1D and 0D structures is reported. Using the same organic and inorganic components, but at different ratios and reaction conditions, both 1D (C 4 N 2 H 14 )SnBr 4 and 0D (C 4 N 2 H 14 Br) 4 SnBr 6 can be prepared in high yields. Moreover, photoinduced structural transformation from 1D to 0D was investigated experimentally and theoretically in which photodissociation of 1D metal halide chains followed by structural reorganization leads to the formation of a more thermodynamically stable 0D structure.

关键词： Lichtinduzierte Strukturänderungen Metallhalogenid-Perowskite Niederdimensionale Strukturen Photolumineszenz Zinn

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Wrinkling Devices: Moisture‐Responsive Wrinkling Surfaces with Tunable Dynamics (Adv. Mater. 24/2017)

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Advanced Materials 2017年第24期29卷

作者： Songshan Zeng Rui Li Stephan G. Freire Vivian M. M. Garbellotto Emily Y. Huang Andrew T. Smith Cong Hu William R. T. Tait Zichao Bian Guoan Zheng Dianyun Zhang Luyi Sun Department of Chemical and Biomolecular Engineering and Polymer Program Institute of Materials Science University of Connecticut Storrs CT 06269 USA Department of Mechanical Engineering University of Connecticut Storrs CT 06269 USA Department of Biomedical Engineering University of Connecticut Storrs CT 06269 USA

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Strategies to improve stimulation efficiency for retinal prostheses

Strategies to improve stimulation efficiency for retinal pro...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Navya S. Davuluri Kiran Nimmagadda Artin Petrossians Mark S. Humayun James D. Weiland Department of Biomedical Engineering University of Southern California Los Angeles CA USA Neuroscience Graduate Program and MD/PhD Program University of Southern California Los Angeles CA USA Mork Family Department of Chemical Engineering and Materials Science University of Southern California Los Angeles CA USA Department of Ophthalmology and the Department of Biomedical Engineering University of Southern California LosAngeles USA

Retinitis Pigmentosa (RP) is a degenerative disease of the retina that leads to vision loss. Retinal prostheses are being developed in order to restore functional vision in patients suffering from RP. We conducted in-vivo experiments in order to identify strategies to efficiently stimulate the retina. We electrically stimulated the retina and measured electrically evoked potentials (EERs) from the superior colliculus of rats. We compared the strength of EERs when voltage-controlled and current-controlled pulses of varying pulse width and charge levels were applied to the retina. In addition to comparing EER strength, we evaluated improvement in power efficiency afforded by a high surface area platinum-iridium material. Voltage-controlled pulses were more efficient than current-controlled pulses when the pulses have a short duration (

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Exploring low internal reorganization energies for silicene nanoclusters

arXiv

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arXiv 2017年

作者： Pablo-Pedro, Ricardo Lopez-Rios, Hector Mendoza-Cortes, Jose-L Kong, Jing Fomine, Serguei van Voorhis, Troy Dresselhaus, Mildred S. Department of Chemistry Massachusetts Institute of Technology 77 Massachusetts Avenue CambridgeMA02139 United States Instituto de Investigaciones en Materiales Universidad Nacional Autónoma de México Apartado Postal 70-360 CU Coyoacán Ciudad de México04510 Mexico Department of Chemical & Biomedical Engineering Florida A&M University Florida State University Joint College of Engineering Tallahassee FL32310 United States Scientific Computing Department Materials Science and Engineering Program High Performance Material Institute Condensed Matter Theory National High Magnetic Field Laboratory Florida State University TallahasseeFL32310 United States Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology CambridgeMA02139 United States Department of Physics Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology CambridgeMA02139 United States

High-performance materials rely on small reorganization energies to facilitate both charge separation and charge transport. Here, we performed DFT calculations to predict small reorganization energies of rectangular silicene nanoclusters with hydrogen-passivated edges denoted by H-SiNC. We observe that across all geometries, H-SiNCs feature large electron affinities and highly stabilized anionic states, indicating their potential as n-type materials. Our findings suggest that fine-tuning the size of H-SiNCs along the "zigzag" and "armchair" directions may permit the design of novel n-type electronic materials and spinctronics devices that incorporate both high electron affinities and very low internal reorganization energies. Copyright © 2017, The Authors. All rights reserved.

关键词： Silicene

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Exploring Low Internal Reorganization Energies for Silicene Nanoclusters

arXiv

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arXiv 2017年

关键词： Silicene

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ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase (vol 557, pg 510, 2018)

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NATURE 2018年第7720期560卷 E35-E35页

作者： Vo, My-Nuong Terrey, Markus Lee, Jeong Woong Roy, Bappaditya Moresco, James J. Sun, Litao Fu, Hongjun Liu, Qi Weber, Thomas G. Yates, John R., III Fredrick, Kurt Schimmel, Paul Ackerman, Susan L. The Skaggs Institute for Chemical Biology Department of Molecular Medicine Scripps Research Institute La Jolla USA Howard Hughes Medical Institute Department of Cellular and Molecular Medicine School of Medicine University of California San Diego La Jolla USA Section of Neurobiology University of California San Diego La Jolla USA Graduate School of Biomedical Sciences and Engineering University of Maine Orono USA The Jackson Laboratory Bar Harbor USA Korea Research Institute of Bioscience and Biotechnology Daejeon South Korea Department of Microbiology The Ohio State University Columbus USA Center for RNA Biology The Ohio State University Columbus USA Department of Chemical Physiology Scripps Research Institute La Jolla USA Salk Institute for Biological Studies La Jolla USA Department of Pathology and Cell Biology Columbia University Medical Center New York USA Taub Institute for Research on Alzheimer’s Disease and the Aging Brain Columbia University Medical Center New York USA Ohio State Biochemistry Program The Ohio State University Columbus USA Sharklet Technologies Aurora USA Dynamic Biosensors GmbH Munich Germany The Scripps Research Institute Jupiter USA

In the Fig. 3b western blot of this Article, 'Myc-AlaRS' in row one should have been 'Myc-AAD Aars', 'AlaRS' in row two should have been 'Aars' and 'ANKRD16' in row four should ...

In the Fig. 3b western blot of this Article, 'Myc-AlaRS' in row one should have been 'Myc-AAD Aars', 'AlaRS' in row two should have been 'Aars' and 'ANKRD16' in row four should have been 'Ankrd16'. In Fig. 4f, 'ANKRD16' and 'ANKRD16(3xR)' should have been 'Ankrd16' and 'Ankrd16; and in Fig. 3c the position of the molecular mass markers had shifted. These figures have been corrected online, and see Supplementary Information to the accompanying Amendment for the original figure.

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