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Multimodal Imaging: Surfactant‐Stripped Frozen Pheophytin Micelles for Multimodal Gut Imaging (Adv. Mater. 38/2016)

Advanced Materials 2016年第38期28卷

作者： Yumiao Zhang Depeng Wang Shreya Goel Boyang Sun Upendra Chitgupi Jumin Geng Haiyan Sun Todd E. Barnhart Weibo Cai Jun Xia Jonathan F. Lovell Department of Biomedical Engineering University at Buffalo The State University of New York Buffalo NY 14260 USA Department of Chemical and Biological Engineering University at Buffalo The State University of New York Buffalo NY 14260 USA Materials Science Program University of Wisconsin–Madison Madison WI 53705 USA Department of Radiology University of Wisconsin–Madison Madison WI 53705 USA Department of Medical Physics University of Wisconsin–Madison Madison WI 53705 USA

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Primary valvular interstitial cell subpopulations isolated based on adhesion strength

Primary valvular interstitial cell subpopulations isolated b...

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Food, Pharmaceutical and Bioengineering Division 2014 - Core programming Area at the 2014 AIChE Annual Meeting

作者： Coombs, Kent E. Rush, Matthew N. Hedberg-Dirk, Elizabeth L. Biomedical Science Graduate Program University of New Mexico AlbuquerqueNM United States Center for Biomedical Engineering University of New Mexico AlbuquerqueNM United States Chemical and Nuclear Engineering University of New Mexico AlbuquerqueNM United States

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The studies of short-chain phosphatidylcholine effect on the spontaneous lipid transfer in phospholipid-based vesicles using differential scanning calorimetry

The studies of short-chain phosphatidylcholine effect on the...

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Student Poster Sessions 2014 - Core programming Area at the 2014 AIChE Annual Meeting

作者： Charubin, Kamil Xia, Yan Nieh, Mu-Ping Department of Chemical and Biomolecular Engineering University of Connecticut StorrsCT United States Polymer Program Institute of Material Science University of Connecticut CT United States Department of Biomedical Engineering University of Connecticut CT United States

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Global, regional, and national sex-specific burden and control of the HIV epidemic, 1990–2019, for 204 countries and territories: the Global Burden of Diseases Study 2019

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The Lancet HIV 2021年第10期8卷 e633-e651页

作者： Jahagirdar, Deepa Walters, Magdalene K. Novotney, Amanda Brewer, Edmond D. Frank, Tahvi D. Carter, Austin Biehl, Molly H. Abbastabar, Hedayat Abhilash, E.S. Abu-Gharbieh, Eman Abu-Raddad, Laith Jamal Adekanmbi, Victor Adeyinka, Daniel Adedayo Adnani, Qorinah Estiningtyas Sakilah Afzal, Saira Aghababaei, Soodabeh Ahinkorah, Bright Opoku Ahmad, Sajjad Ahmadi, Keivan Ahmadi, Sepideh Ahmadpour, Ehsan Ahmed, Muktar Beshir Rashid, Tarik Ahmed Salih, Yusra Ahmed Aklilu, Addis Akram, Tayyaba Akunna, Chisom Joyqueenet Al Hamad, Hanadi Alahdab, Fares Alanezi, Fahad Mashhour Aleksandrova, Ekaterina A. Alene, Kefyalew Addis Ali, Liaqat Alipour, Vahid Almustanyir, Sami Alvis-Guzman, Nelson Ameyaw, Edward Kwabena Amu, Hubert Andrei, Catalina Liliana Andrei, Tudorel Anvari, Davood Arabloo, Jalal Aremu, Olatunde Arulappan, Judie Atnafu, Desta Debalkie Quintanilla, Beatriz Paulina Ayala Ayza, Muluken Altaye Azari, Samad Darshan, B.B. Banach, Maciej Bärnighausen, Till Winfried Barra, Fabio Barrow, Amadou Basu, Sanjay Bazargan-Hejazi, Shahrzad Belay, Habtamu Gebrehana Berheto, Tezera Moshago Bezabhe, Woldesellassie Mequanint Bezabih, Yihienew Mequanint Bhagavathula, Akshaya Srikanth Bhardwaj, Nikha Bhardwaj, Pankaj Bhattacharyya, Krittika Bibi, Sadia Bijani, Ali Bisignano, Catherine Bolarinwa, Obasanjo Afolabi Boloor, Archith Boltaev, Azizbek A. Briko, Nikolay Ivanovich Buonsenso, Danilo Burkart, Katrin Butt, Zahid A. Cao, Chao Charan, Jaykaran Chatterjee, Souranshu Chattu, Soosanna Kumary Chattu, Vijay Kumar Choudhari, Sonali Gajanan Chu, Dinh-Toi Couto, Rosa A.S. Cowden, Richard G. Dachew, Berihun Assefa Dadras, Omid Dagnew, Amare Belachew Dahlawi, Saad M.A. Dai, Xiaochen Dandona, Lalit Dandona, Rakhi das Neves, José Degenhardt, Louisa Demeke, Feleke Mekonnen Desta, Abebaw Alemayehu Deuba, Keshab Dhamnetiya, Deepak Dhungana, Govinda Prasad Dianatinasab, Mostafa Diaz, Daniel Djalalinia, Shirin Doan, Linh Phuong Dorostkar, Fariba Edinur, Hisham Atan Effiong, Andem Eftekharzadeh, Sahar El Sayed Zaki, Maysaa Elayedath, Rajesh Elhadi, Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Division of Allergy and Infectious Diseases University of Washington Seattle WA United States Department of Global Health University of Washington Seattle WA United States School of Social Work University of Washington Seattle WA United States Department of Medicine University of Washington Seattle WA United States Vagelos College of Physicians and Surgeones Columbia University Medical Center New York NY United States Division of Data Analytics and Delivery for Impact WHO Geneva Switzerland Advanced Diagnostic and Interventional Radiology Research Centre Tehran University of Medical Sciences Tehran Iran Multiple Sclerosis Research Centre Tehran University of Medical Sciences Tehran Iran School of Public Health Tehran University of Medical Sciences Tehran Iran Department of Epidemiology and Biostatistics Tehran University of Medical Sciences Tehran Iran Paediatric Chronic Kidney Disease Research Centre Tehran University of Medical Sciences Tehran Iran Department of Psychiatry Tehran University of Medical Sciences Tehran Iran Metabolomics and Genomics Research Centre Tehran University of Medical Sciences Tehran Iran Sina Trauma and Surgery Research Centre Tehran University of Medical Sciences Tehran Iran Research Centre for Immunodeficiencies Tehran University of Medical Sciences Tehran Iran Non-Communicable Diseases Research Centre Tehran University of Medical Sciences Tehran Iran Department of Botany Sree Narayana Guru College Chelannur Kozhikode India Clinical Sciences Department University of Sharjah Sharjah United Arab Emirates Mass Communication Department University of Sharjah Sharjah United Arab Emirates Department of Health-Care Policy and Research Weill Cornell Medical College in Qatar Doha Qatar Department of Population Medicine Ca

Background: The sustainable development goals (SDGs) aim to end HIV/AIDS as a public health threat by 2030. Understanding the current state of the HIV epidemic and its change over time is essential to this effort. This study assesses the current sex-specific HIV burden in 204 countries and territories and measures progress in the control of the epidemic. Methods: To estimate age-specific and sex-specific trends in 48 of 204 countries, we extended the Estimation and Projection Package Age-Sex Model to also implement the spectrum paediatric model. We used this model in cases where age and sex specific HIV-seroprevalence surveys and antenatal care-clinic sentinel surveillance data were available. For the remaining 156 of 204 locations, we developed a cohort-incidence bias adjustment to derive incidence as a function of cause-of-death data from vital registration systems. The incidence was input to a custom Spectrum model. To assess progress, we measured the percentage change in incident cases and deaths between 2010 and 2019 (threshold >75% decline), the ratio of incident cases to number of people living with HIV (incidence-to-prevalence ratio threshold <0·03), and the ratio of incident cases to deaths (incidence-to-mortality ratio threshold <1·0). Findings: In 2019, there were 36·8 million (95% uncertainty interval [UI] 35·1–38·9) people living with HIV worldwide. There were 0·84 males (95% UI 0·78–0·91) per female living with HIV in 2019, 0·99 male infections (0·91–1·10) for every female infection, and 1·02 male deaths (0·95–1·10) per female death. Global progress in incident cases and deaths between 2010 and 2019 was driven by sub-Saharan Africa (with a 28·52% decrease in incident cases, 95% UI 19·58–35·43, and a 39·66% decrease in deaths, 36·49–42·36). Elsewhere, the incidence remained stable or increased, whereas deaths generally decreased. In 2019, the global incidence-to-prevalence ratio was 0·05 (95% UI 0·05–0·06) and the global incidence-to-mortality ratio was

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Optimizing recombinant antibodies for intracellular function using hitchhiker-mediated survival selection

Optimizing recombinant antibodies for intracellular function...

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作者： Waraho-Zhmayev, Dujduan Meksiriporn, Bunyarit Portnoff, Alyse D. DeLisa, Matthew P. Bradbury, Andrew School of Chemical and Biomolecular Engineering Cornell University IthacaNY14853 United States Biological Engineering Program Faculty of Engineering King Mongkut's University of Technology Thonburi 126 Pracha-utid Road Bangmod Toongkru Bangkok10140 Thailand Department of Biomedical Engineering Cornell University IthacaNY14853 United States

The 'hitchhiker' mechanism of the bacterial twin-arginine translocation pathway has previously been adapted as a genetic selection for detecting pairwise protein interactions in the cytoplasm of living Escherichia coli cells. Here, we extended this method, called FLI-TRAP, for rapid isolation of intracellular antibodies (intrabodies) in the single-chain Fv format that possess superior traits simply by demanding bacterial growth on high concentrations of antibiotic. Following just a single round of survival-based enrichment using FLI-TRAP, variants of an intrabody against the dimerization domain of the yeast Gcn4p transcription factor were isolated having significantly greater intracellular stability that translated to yield enhancements of >10-fold. Likewise, an intrabody specific for the non-amyloid component region of a-synuclein was isolated that has ∼8-fold improved antigen-binding affinity. Collectively, our results illustrate the potential of the FLI-TRAP method for intracellular stabilization and affinity maturation of intrabodies, all without the need for purification or immobilization of the antigen. © The Author 2014. Published by Oxford University Press. All rights reserved.

关键词： Escherichia coli

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Cover Picture: Precise Design of Phosphorescent Molecular Butterflies with Tunable Photoinduced Structural Change and Dual Emission (Angew. Chem. Int. Ed. 33/2015)

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Angewandte Chemie International Edition 2015年第33期54卷

作者： Chenkun Zhou Yu Tian Dr. Zhao Yuan Dr. Mingu Han Jamie Wang Prof. Lei Zhu Maliheh Shaban Tameh Prof. Chen Huang Prof. Biwu Ma Chemical and Biomedical Engineering FAMU-FSU College of Engineering (USA) Materials Science Program Florida State University (USA) Department of Chemistry and Biochemistry Florida State University (USA) Department of Scientific Computing Florida State University (USA) Chen Huang Materials Science Program Florida State University (USA) Biwu Ma Chemical and Biomedical Engineering FAMU-FSU College of Engineering (USA)

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Erratum to: Open-source, small-animal magnetic resonance-guided focused ultrasound system

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Journal of therapeutic ultrasound 2016年第1期4卷 29页

作者： Megan E Poorman Vandiver L Chaplin Ken Wilkens Mary D Dockery Todd D Giorgio William A Grissom Charles F Caskey Department of Biomedical Engineering Vanderbilt University PMB 351631 2301 Vanderbilt Place Nashville TN 37235 USA. Department of Biomedical Engineering Vanderbilt University PMB 351631 2301 Vanderbilt Place Nashville TN 37235 USA Chemical and Physical Biology Program Vanderbilt University 1161 21st Avenue South Nashville TN 37232 USA. Institute of Imaging Science Vanderbilt University 1161 21st Avenue South Nashville TN 37232 USA. Institute of Imaging Science Vanderbilt University 1161 21st Avenue South Nashville TN 37232 USA Department of Radiology Vanderbilt University 1161 21st Avenue South Nashville TN 37232 USA.

[This corrects the article DOI: 10.1186/s40349-016-0066-7.].

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Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers Abstracts

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FLUIDS AND BARRIERS OF THE CNS 2017年第SUPPL 2期14卷 27-27页

作者： [Anonymous] The Jerzy Kukuczka Academy of Physical Education Katowice Poland The Institute of Animal Physiology and Food Research Polish Academy of Sciences Olsztyn Poland University of Miami Miami FL USA Institute of Pharmaceutical Science King’s College London London United Kingdom Department of Ophthalmology and Molecular and Integrative Physiology The University of Michigan Ann Arbor MI USA Department of Internal Medicine and Cardiology The University of Michigan Ann Arbor MI USA School of Medicine Department of Cellular and Molecular Medicine Koc University Istanbul Turkey Department of Cellular and Molecular Medicine Medical Faculty Koc University Istanbul Turkey Department of Neuroscience School of Medicine Koc University Istanbul Turkey Department of Neuroscience Medical Faculty Koc University Istanbul Turkey Department of Laboratory Animals Science Aziz Sancar Experimental Medicine Research Institute Istanbul University Istanbul Turkey Department of Neuroscience Aziz Sancar Experimental Medicine Research Institute Istanbul University Istanbul Turkey School of Medicine Koc University Istanbul Turkey Department of Forensic Science Istanbul Faculty of Medicine Istanbul University Istanbul Turkey Department of Histology and Embryology School of Medicine Koc University Istanbul Turkey Department of Histology and Embryology Istanbul Faculty of Medicine Istanbul University Istanbul Turkey Department of Physiology School of Medicine Koc University Istanbul Turkey Theodor Kocher Institute University of Bern Bern Switzerland Institute of Veterinary Physiology Vetsuisse Faculty University of Zurich Zurich Switzerland Zurich Center for Integrative Human Physiology University of Zurich Zurich Switzerland Zurich Center of Integrative Human Physiology University of Zurich Zurich Switzerland Institute for Veterinary Physiology and Zurich Center for Integrative Human Physiology University of Zurich Zurich Switzerland Institute of Veterinary Physiology Univer

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Intraocular retinal prostheses: Monocular depth perception in the low resolution limit

Intraocular retinal prostheses: Monocular depth perception i...

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Laser Science, LS 2014

作者： Stiles, N.R. McIntosh, B.P. Tanguay, A.R. Humayun, M.S. Computation and Neural Systems Program California Institute of Technology PasadenaCAMC 136-93 United States Electrical Engineering-Electrophysics University of Southern California United States Electrical Engineering-Electrophysics Chemical Engineering Material Sci. Biomed. Engg. Ophthalmology Physics and Astronomy and Neuroscience Grad. Program University of Southern California United States Ophthalmology Cell and Neurobiology and Biomedical Engineering University of Southern California United States

Depth perception via monocular cues was studied with a reach and grasp task in a retinal prosthesis simulator at low resolution. Results indicate that depth perception may be possible with retinal prostheses implanted... 详细信息

ISBN: (纸本)1557522863

关键词： Ophthalmology

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Targeted blood-brain barrier disruption: Polymersomes used as mannitol carriers

Targeted blood-brain barrier disruption: Polymersomes used a...

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Food, Pharmaceutical and Bioengineering Division 2014 - Core programming Area at the 2014 AIChE Annual Meeting

作者： Larsen, Jessica Martin, Douglas Byrne, Mark Biomimetic and Biohybrid Materials Biomedical Devices and Drug Delivery Laboratories Department of Chemical Engineering United States Scott-Ritchey Research Center College of Veterinary Medicine United States US Department of Education GAANN Graduate Fellowship Program in Biological Pharmaceutical Engineering Auburn University AuburnAL United States

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