The material concept of resin cements capable of disintegrating due to near-infrared (NIR) radiation was verified. The cements were prepared by adding silicon carbide (SiC), which heats upon absorbing NIR rays, and th...
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Herein, we reported the in-situ preparation of manganese ferrite (MnFe2O4) grafted polyaniline (Pani), a magnetic nanocomposite for the potential visible light photocatalytic material as well as electrode material for...
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作者：
Bakr, Hend A.Salama, Ahmed M.Fares, AhmedZaky, Ahmed B.Cairo University
Biomedical Engineering Program Faculty of Engineering Giza Egypt Benha University
Computer Systems Engineering Program Faculty of Engineering at Shoubra Banha Egypt
Computer science and information technology Programs Alexandria Egypt Benha University
On leave from Computer Systems Engineering Program Faculty of Engineering at Shoubra Egypt
Physician scheduling is a critical task that impacts the quality of patient care, staff satisfaction, and operational efficiency in healthcare institutions. The traditional approach to physician scheduling is manual a...
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We demonstrate elliptical beam shaping in a miniaturized two-photon microscope enabling cellular resolution fluorescence imaging at over three times faster frame rate than point scanning over a 400 µm diameter FO...
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Model Predictive Control (MPC) is an optimal control technique where control action is obtained by minimizing the objective (cost) function subject to the model equation of the plant. In this basic study, the feasibil...
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Neurodegenerative diseases,a group of disorders associated with advanced age,are typified by the disease-specific accumulation of mutant proteins and *** decades,treatment modalities for these disorders have focused o...
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Neurodegenerative diseases,a group of disorders associated with advanced age,are typified by the disease-specific accumulation of mutant proteins and *** decades,treatment modalities for these disorders have focused on addressing neuronal malfu nction,which has resulted in the failure of *** studies have identified the crucial role of glial cells in exacerbating neurodegenerative processes via the release of neuroinflammatory ***,the major immune component of the central nervous system (CNS),undergo numerous phenotypic transitions and regulate the outcomes of various pathologies (Afridi et al.,2022).
Transplanting cell cultured brown adipocytes(BAs)represents a promising approach to prevent and treat obesity(OB)and its associated metabolic disorders,including type 2 diabetes mellitus(T2DM).However,transplanted BAs...
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Transplanting cell cultured brown adipocytes(BAs)represents a promising approach to prevent and treat obesity(OB)and its associated metabolic disorders,including type 2 diabetes mellitus(T2DM).However,transplanted BAs have a very low survival rate in *** enzymatic dissociation during the harvest of fully differentiated BAs also loses significant *** is a critical need for novel methods that can avoid cell death during cell preparation,transplantation,and in ***,we reported that preparing BAs as injectable microtissues could overcome the *** found that 3D culture promoted BA differentiation and UCP-1 expression,and the optimal initial cell aggregate size was 100μ*** microtissues could be produced at large scales via 3D suspension assisted with a PEG hydrogel and could be *** microtissues could survive in vivo for long *** alleviated body weight and fat gain and improved glucose tolerance and insulin sensitivity in high-fat diet(HFD)-induced OB and T2DM *** microtissues impacted multiple organs,secreted protein factors,and influenced the secretion of endogenous *** our best knowledge,this is the first report on fabricating human BA microtissues and showing their safety and efficacy in T2DM *** proposal of transplanting fabricated BA microtissues,the microtissue fabrication method,and the demonstration of efficacy in T2DM mice are all *** results show that engineered 3D human BA microtissues have considerable advantages in product scalability,storage,purity,safety,dosage,survival,and efficacy.
Molecular diagnostic technologies empower new clinical opportunities in precision ***,existing approaches face limitations with respect to performance,operation and *** molecules including proteins and nucleic acids a...
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Molecular diagnostic technologies empower new clinical opportunities in precision ***,existing approaches face limitations with respect to performance,operation and *** molecules including proteins and nucleic acids are being increasingly adopted as tools in the development of new molecular diagnostic *** particular,leveraging their complementary properties—the functional diversity of proteins and the precision programmability of nucleic acids—a wide range of protein–nucleic acid hybrid nanostructures have been *** hybrid structures take diverse forms,ranging from one-dimensional to three-dimensional hybrids,as static assemblies to dynamic machines,and possess myriad functions to recognize target biomarkers,encode vast information and execute catalytic *** by recent advances in this area of molecular nanotechnology,we review the state-of-art design and application of various types of protein–nucleic acid hybrid nanostructures for molecular diagnostics,and present an outlook on the challenges and opportunities for emerging pre-clinical and clinical applications,highlighting the promise for earlier detection,more refined diagnosis and highly tailored treatment decision that ultimately lead to improved patient outcomes.
Electrocardiographic imaging (ECGI) is a non-invasive technique for reconstructing cardiac electrical activity from body surface electrocardiogram (ECG) signals. The collection of ECG signals from the body surface is ...
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