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Conotruncal Heart Defects: Altered Tissue Morphology and Hemodynamics

Microscopy and Microanalysis 2017年第S1期23卷 1174-1175页

作者： Rebecca S Jones Lorain Junor Mary R Hutson Margaret L Kirby Richard L Goodwin Biomedical Engineering Program College of Engineering and Computing University of South Carolina Columbia SC 29208 USA Department of Cell Biology and Anatomy University of South Carolina School of Medicine Columbia SC 29209 USA Department of Pediatrics (Neonatology) Neonatal-Perinatal Research Institute Duke University Medical Center Durham NC 297710 USA Department of Cell Biology Duke University Medical Center Durham NC 297710 USA Department of Biomedical Sciences University of South Carolina School of Medicine Greenville Greenville SC 29605 USA

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Computer-aided identification and quantitative system for assessment of knee cartilage thickness using ultrasound images

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Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology 2017年 9卷 99-100页

作者： Chung-Chien Lee Ruey-Feng Chang Hang Lin Kuang-Che Chang Chien Department of Orthopedic Surgery New Taipei City Hospital Taiwan Department of Graduate Institute of Biomedical Electronics And Bioinformatics National Taiwan University Taiwan Department of Orthopedic Surgery National Taiwan University Hospital Taiwan Department of Computer Science And Information Engineering National Taiwan University Taiwan

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WE-DE-207B-11: Implementation of Size-Specific 3D Beam Modulation Filters On a Dedicated Breast CT Platform Using Breast Immobilization

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Medical Physics 2016年第6PART40期43卷 3819-3820页

作者： A Hernandez J Boone Department of Radiology Biomedical Engineering Graduate Group University of California Davis Sacramento CA Departments of Radiology and Biomedical Engineering University of California Davis Sacramento CA

Purpose: To implement a 3D beam modulation filter (3D-BMF) in dedicated breast CT (bCT) and develop a method for conforming the patient's breast to a pre-defined shape, optimizing the effects of the filter. This work expands on previous work reporting the methodology for designing a 3D-BMF that can spare unnecessary dose and improve signal equalization at the detector by preferentially filtering the beam in the thinner anterior and peripheral breast regions. Methods: Effective diameter profiles were measured for 219 segmented bCT images, grouped into volume quintiles, and averaged within each group to represent the range of breast sizes found clinically. These profiles were then used to generate five size-specific computational phantoms and fabricate five size-specific UHMW phantoms. Each computational phantom was utilized for designing a size-specific 3D-BMF using previously reported methods. Glandular dose values and projection images were simulated in MCNP6 with and without the 3DBMF using the system specifications of our prototype bCT scanner “Doheny”. Lastly, thermoplastic was molded around each of the five phantom sizes and used to produce a series of breast immobilizers for use in conforming the patient's breast during bCT acquisition. Results: After incorporating the 3D-BMF, MC simulations estimated an 80% average reduction in the detector dynamic range requirements across all phantom sizes. The glandular dose was reduced on average 57% after normalizing by the number of quanta reaching the detector under the thickest region of the breast. Conclusion: A series of bCT-derived breast phantoms were used to design size-specific 3D-BMFs and breast immobilizers that can be used on the bCT platform to conform the patient's breast and therefore optimally exploit the benefits of the 3D-BMF. Current efforts are focused on fabricating several prototype 3D-BMFs and performing phantom scans on Doheny for MC simulation validation and image quality analysis. Research repor

关键词： Three dimensional sensing Image sensors Computed tomography Monte Carlo methods Three dimensional image processing Medical image segmentation Image scanners Particle beam detectors Medical image quality

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Using a smartwatch with real-time feedback instructions improves the delivery of high-quality cardiopulmonary resuscitation

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Resuscitation 2018年 130卷 e109-e109页

作者： Lu, Tsung-Chien Chang, Yao-Ting Ho, Te-Wei Chen, Yi Lee, Yi-Ting Wang, Yu-Siang Chen, Yen-Pin Tsai, Chu-Lin Ma, Matthew Huei-Ming Fang, Cheng-Chung Lai, Feipei Turner, Anne Department of Emergency Medicine National Taiwan University Hospital Taipei Taiwan Biomedical and Health Informatics University of Washington Seattle United States Department of Computer Science and Information Engineering National Taiwan University Taipei Taiwan Graduate Inst. of Biomedical Electronics and Bioinformatics National Taiwan University Taipei Taiwan Department of Physics National Taiwan University Taipei Taiwan

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Hearing loss prevalence and years lived with disability, 1990-2019: Findings from the Global Burden of Disease Study 2019

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The Lancet 2021年第10278期397卷 996-1009页

作者： Haile, Lydia M. Kamenov, Kaloyan Briant, Paul Svitil Orji, Aislyn U. Steinmetz, Jaimie D. Abdoli, Amir Abdollahi, Mohammad Abu-Gharbieh, Eman Afshin, Ashkan Ahmed, Haroon Rashid, Tarik Ahmed Akalu, Yonas Alahdab, Fares Alanezi, Fahad Mashhour Alanzi, Turki M. Al Hamad, Hanadi Ali, Liaqat Alipour, Vahid Al-Raddadi, Rajaa M. Amu, Hubert Arabloo, Jalal Arab-Zozani, Morteza Arulappan, Judie Ashbaugh, Charlie Atnafu, Desta Debalkie Babar, Zaheer-Ud-Din Baig, Atif Amin Banik, Palash Chandra Bärnighausen, Till Winfried Barrow, Amadou Bender, Rose G. Bhagavathula, Akshaya Srikanth Bhardwaj, Nikha Bhardwaj, Pankaj Bibi, Sadia Bijani, Ali Burkart, Katrin Cederroth, Christopher R. Charan, Jaykaran Choudhari, Sonali Gajanan Chu, Dinh-Toi Couto, Rosa A.S. Dagnew, Amare Belachew Dagnew, Baye Dahlawi, Saad M.A. Dai, Xiaochen Dandona, Lalit Dandona, Rakhi Desalew, Assefa Dhamnetiya, Deepak Dhimal, Mandira Lamichhane Dhimal, Meghnath Doyle, Kerrie E. Duncan, Bruce B. Ekholuenetale, Michael Filip, Irina Fischer, Florian Franklin, Richard Charles Gaidhane, Abhay Motiramji Gaidhane, Shilpa Gallus, Silvano Ghamari, Farhad Ghashghaee, Ahmad Ghozali, Ghozali Gilani, Syed Amir Glǎvan, Ionela-Roxana Golechha, Mahaveer Goulart, Barbara Niegia Garcia Gupta, Veer Bala Gupta, Vivek Kumar Hamidi, Samer Hammond, Billy Randall Hay, Simon I. Hayat, Khezar Heidari, Golnaz Hoffman, Howard J. Hopf, Kathleen Pillsbury Hosseinzadeh, Mehdi Househ, Mowafa Hussain, Rabia Hwang, Bing-Fang Iavicoli, Ivo Ibitoye, Segun Emmanuel Ilesanmi, Olayinka Stephen Irvani, Seyed Sina Naghibi Islam, Sheikh Mohammed Shariful Iwagami, Masao Jacob, Louis Jayapal, Sathish Kumar Jha, Ravi Prakash Jonas, Jost B. Kalhor, Rohollah Al-Salihi, Nawzad Kameran Kandel, Himal Kasa, Ayele Semachew Kayode, Gbenga A. Khalilov, Rovshan Khan, Ejaz Ahmad Khatib, Mahalaqua Nazli Kosen, Soewarta Koyanagi, Ai Kumar, G. Anil Landires, Ivan Lasrado, Savita Lim, Stephen S. Liu, Xuefeng Lobo, Stany W. Lugo, Alessandra Makki, Alaa Mendoza, Walter Mersha, Amanual Getnet Mihretie, Kebadnew Mulatu Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Noncommunicable Diseases World Health Organization (WHO) Geneva Switzerland Department of Parasitology and Mycology Jahrom University of Medical Sciences Jahrom Iran The Institute of Pharmaceutical Sciences (TIPS) Tehran University of Medical Sciences Tehran Iran School of Pharmacy Tehran University of Medical Sciences Tehran Iran Clinical Sciences Department University of Sharjah Sharjah United Arab Emirates Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Department of Biosciences COMSATS Institute of Information Technology Islamabad Pakistan Department of Computer Science and Engineering University of Kurdistan Hewler Erbil Iraq Department of Medical Physiology University of Gondar Gondar Ethiopia Mayo Evidence-based Practice Center Mayo Clinic Foundation for Medical Education and Research Rochester MN United States Imam Abdulrahman Bin Faisal University Dammam Saudi Arabia Health Information Management and Technology Department Dammam Saudi Arabia Geriatric and Long Term Care Department Hamad Medical Corporation Doha Qatar Rumailah Hospital Hamad Medical Corporation Doha Qatar Department of Biological Sciences National University of Medical Sciences (NUMS) Rawalpindi Pakistan Health Management and Economics Research Center Tehran Iran Department of Community Medicine King Abdulaziz University Jeddah Saudi Arabia Department of Population and Behavioural Sciences University of Health and Allied Sciences Ho Ghana Social Determinants of Health Research Center Birjand University of Medical Sciences Birjand Iran Department of Maternal and Child Health Sultan Qaboos University Muscat Oman Department of Health System and Health Economics Bahir Dar University Bahir Dar Ethiopia Department of Pharmacy University of Huddersfield Huddersfield United Kingdom Unit of Biochemistry Universiti

Background: Hearing loss affects access to spoken language, which can affect cognition and development, and can negatively affect social wellbeing. We present updated estimates from the Global Burden of Disease (GBD) study on the prevalence of hearing loss in 2019, as well as the condition's associated disability. Methods: We did systematic reviews of population-representative surveys on hearing loss prevalence from 1990 to 2019. We fitted nested meta-regression models for severity-specific prevalence, accounting for hearing aid coverage, cause, and the presence of tinnitus. We also forecasted the prevalence of hearing loss until 2050. Findings: An estimated 1·57 billion (95% uncertainty interval 1·51–1·64) people globally had hearing loss in 2019, accounting for one in five people (20·3% [19·5–21·1]). Of these, 403·3 million (357·3–449·5) people had hearing loss that was moderate or higher in severity after adjusting for hearing aid use, and 430·4 million (381·7–479·6) without adjustment. The largest number of people with moderate-to-complete hearing loss resided in the Western Pacific region (127·1 million people [112·3–142·6]). Of all people with a hearing impairment, 62·1% (60·2–63·9) were older than 50 years. The Healthcare Access and Quality (HAQ) Index explained 65·8% of the variation in national age-standardised rates of years lived with disability, because countries with a low HAQ Index had higher rates of years lived with disability. By 2050, a projected 2·45 billion (2·35–2·56) people will have hearing loss, a 56·1% (47·3–65·2) increase from 2019, despite stable age-standardised prevalence. Interpretation: As populations age, the number of people with hearing loss will increase. Interventions such as childhood screening, hearing aids, effective management of otitis media and meningitis, and cochlear implants have the potential to ameliorate this burden. Because the burden of moderate-to-complete hearing loss is concentrated in countries with low health-ca

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Author Correction: The interrelation of sleep and mental and physical health is anchored in grey-matter neuroanatomy and under genetic control

Communications biology

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Communications biology 2020年第1期3卷 290页

作者： Masoud Tahmasian Fateme Samea Habibolah Khazaie Mojtaba Zarei Shahrzad Kharabian Masouleh Felix Hoffstaedter Julia Camilleri Peter Kochunov B T Thomas Yeo Simon Bodo Eickhoff Sofie Louise Valk Institute of Medical Science and Technology Shahid Beheshti University Tehran Iran. Sleep Disorders Research Center Kermanshah University of Medical Sciences Kermanshah Iran. Institute of Neuroscience and Medicine (INM-7: Brain and Behaviour) Research Centre Jülich 52425 Jülich Germany. Institute of Systems Neuroscience Heinrich Heine University Düsseldorf 40225 Düsseldorf Germany. Maryland Psychiatric Research Center University of Maryland School of Medicine Baltimore MD 21201 USA. Department of Electrical and Computer Engineering Clinical Imaging Research Centre N.1 Institute for Health and Memory Networks Program National University of Singapore Singapore 119077 Singapore. Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital Charlestown MA 02114 USA. Centre for Sleep and Cognition National University of Singapore Singapore 119077 Singapore. NUS Graduate School for Integrative Sciences and Engineering National University of Singapore Singapore 119077 Singapore. Institute of Neuroscience and Medicine (INM-7: Brain and Behaviour) Research Centre Jülich 52425 Jülich Germany. svalk@fz-juelich.de. Institute of Systems Neuroscience Heinrich Heine University Düsseldorf 40225 Düsseldorf Germany. svalk@fz-juelich.de.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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A new margin-based AdaBoost algorithm: Even more robust than RobustBoost to class-label noise

A new margin-based AdaBoost algorithm: Even more robust than...

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Canadian Conference on Electrical and Computer engineering (CCECE)

作者： Omid Ranjbar Pouya Biomedical Engineering Program University of Manitoba Winnipeg Canada

ISBN: (纸本)9781467387224

In this paper, we present a new modification of AdaBoost (Adaptive-Boosting) algorithm that improves its efficiency in presence of class-label noise. The proposed algorithm is significantly more robust against label noise than RobusBoost, the best available and implemented solution. Moreover, unlike RobusBoost, the proposed method does not need optimization toolbox or external parameters provided by user. The empirical results on 9 benchmark datasets showed the proposed method significantly outperforms RobustBoost in terms of classification accuracy and computation time in majority of the examined data sets.

关键词： Training Robustness Noise measurement Classification algorithms Benchmark testing Machine learning algorithms Signal processing algorithms

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Erratum to: A Reference Genome Assembly of Simmental Cattle, Bos taurus taurus

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The Journal of heredity 2021年第6期112卷 565页

作者： Michael P Heaton Timothy P L Smith Derek M Bickhart Brian L Vander Ley Larry A Kuehn Jonas Oppenheimer Wade R Shafer Fred T Schuetze Brad Stroud Jennifer C McClure Jennifer P Barfield Harvey D Blackburn Theodore S Kalbfleisch Kimberly M Davenport Kristen L Kuhn Richard E Green Beth Shapiro Benjamin D Rosen USDA ARS U.S. Meat Animal Research Center Clay Center NE USA. USDA ARS U.S. Dairy Forage Research Center Madison WI USA. Great Plains Veterinary Educational Center University of Nebraska-Lincoln Lincoln NE USA. Department of Biomolecular Engineering University of California Santa Cruz CA USA. American Simmental Association Bozeman MT USA. Simmentals of Texas Granbury TX USA. Stroud Veterinary Embryo Services Weatherford TX USA. College of Veterinary Medicine and Biomedical Sciences Colorado State University Fort Collins CO USA. USDA ARS National Animal Germplasm Program Fort Collins CO USA. Gluck Equine Research Center University of Kentucky Lexington KY USA. Department of Animal Veterinary and Food Science University of Idaho Moscow ID USA. Department of Ecology and Evolutionary Biology University of California Santa Cruz CA USA. Howard Hughes Medical Institute University of California Santa Cruz Santa Cruz CA USA. USDA ARS Animal Genomics and Improvement Laboratory Beltsville MD USA.

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Cryo-Electron Microscopy: Cryo-EM-On-a-Chip: Custom-Designed Substrates for the 3D Analysis of Macromolecules (Small 21/2019)

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Small 2019年第21期15卷

作者： Nick A. Alden A. Cameron Varano William J. Dearnaley Maria J. Solares William Y. Luqiu Yanping Liang Zhi Sheng Sarah M. McDonald John Damiano Jennifer McConnell Madeline J. Dukes Deborah F. Kelly Virginia Tech Carilion Research Institute Virginia Tech Roanoke VA 24016 USA Department of Biomedical Engineering Pennsylvania State University University Park PA 16802 USA Center for Structural Oncology Pennsylvania State University University Park PA 16802 USA Translational Biology Medicine and Health Graduate Program Virginia Tech Blacksburg VA 24061 USA Huck Institutes of the Life Sciences Pennsylvania State University University Park PA 16802 USA Department of Biology Wake Forest University Winston-Salem NC 27109 USA Application Science Protochips Inc. Morrisville NC 27560 USA

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A broadband thermal emission spectrum of the ultra-hot Jupiter WASP-18b

arXiv

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arXiv 2023年

作者： Coulombe, Louis-Philippe Benneke, Björn Challener, Ryan Piette, Anjali A.A. Wiser, Lindsey S. Mansfield, Megan MacDonald, Ryan J. Beltz, Hayley Feinstein, Adina D. Radica, Michael Savel, Arjun B. Dos Santos, Leonardo A. Bean, Jacob L. Parmentier, Vivien Wong, Ian Rauscher, Emily Komacek, Thaddeus D. Kempton, Eliza M.-R. Tan, Xianyu Hammond, Mark Lewis, Neil T. Line, Michael R. Lee, Elspeth K.H. Shivkumar, Hinna Crossfield, Ian J.M. Nixon, Matthew C. Rackham, Benjamin V. Wakeford, Hannah R. Welbanks, Luis Zhang, Xi Batalha, Natalie M. Berta-Thompson, Zachory K. Changeat, Quentin Désert, Jean-Michel Espinoza, Néstor Goyal, Jayesh M. Harrington, Joseph Knutson, Heather A. Kreidberg, Laura López-Morales, Mercedes Shporer, Avi Sing, David K. Stevenson, Kevin B. Aggarwal, Keshav Ahrer, Eva-Maria Alam, Munazza K. Bell, Taylor J. Blecic, Jasmina Caceres, Claudio Carter, Aarynn L. Casewell, Sarah L. Crouzet, Nicolas Cubillos, Patricio E. Decin, Leen Fortney, Jonathan J. Gibson, Neale P. Heng, Kevin Henning, Thomas Iro, Nicolas Kendrew, Sarah Lagage, Pierre-Olivier Leconte, Jérémy Lendl, Monika Lothringer, Joshua D. Mancini, Luigi Mikal-Evans, Thomas Molaverdikhani, Karan Nikolov, Nikolay K. Ohno, Kazumasa Palle, Enric Piaulet, Caroline Redfield, Seth Roy, Pierre-Alexis Tsai, Shang-Min Venot, Olivia Wheatley, Peter J. Department of Physics Trottier Institute for Research on Exoplanets Université de Montréal MontréalQC Canada Department of Astronomy University of Michigan Ann ArborMI United States Earth and Planets Laboratory Carnegie Institution for Science WashingtonDC United States School of Earth and Space Exploration Arizona State University TempeAZ United States Steward Observatory University of Arizona TucsonAZ United States NHFP Sagan Fellow United States Department of Astronomy Carl Sagan Institute Cornell University NY United States Department of Astronomy and Astrophysics University of Chicago ChicagoIL United States NSF Graduate Research Fellow United States Department of Astronomy University of Maryland College ParkMD United States Center for Computational Astrophysics Flatiron Institute New YorkNY United States Space Telescope Science Institute BaltimoreMD United States Université Côte d’Azur Observatoire de la Côte d’Azur CNRS Laboratoire Lagrange France NASA Goddard Space Flight Center GreenbeltMD United States NASA Postdoctoral Program Fellow United States Tsung-Dao Lee Institute Shanghai Jiao Tong University Shanghai China School of Physics and Astronomy Shanghai Jiao Tong University Shanghai China Atmospheric Oceanic and Planetary Physics Department of Physics University of Oxford Oxford United Kingdom Department of Mathematics and Statistics Faculty of Environment Science and Economy University of Exeter Exeter United Kingdom Center for Space and Habitability University of Bern Bern Switzerland Anton Pannekoek Institute for Astronomy University of Amsterdam Amsterdam Netherlands Department of Physics & Astronomy University of Kansas LawrenceKS United States Department of Earth Atmospheric and Planetary Sciences Massachusetts Institute of Technology CambridgeMA United States Kavli Institute for Astrophysics and Space Research Massachusetts Institute of Technology CambridgeMA United States 51 Pegasi b Fellow France School of

Close-in giant exoplanets with temperatures greater than 2,000 K ("ultra-hot Jupiters") have been the subject of extensive efforts to determine their atmospheric properties using thermal emission measurements from the Hubble and Spitzer Space Telescopes1;2;3. However, previous studies have yielded inconsistent results because the small sizes of the spectral features and the limited information content of the data resulted in high sensitivity to the varying assumptions made in the treatment of instrument systematics and the atmospheric retrieval analysis3;4;5;6;7;8;9;10;11;12. Here we present a dayside thermal emission spectrum of the ultrahot Jupiter WASP-18b obtained with the NIRISS13 instrument on JWST. The data span 0.85 to 2.85 µm in wavelength at an average resolving power of 400 and exhibit minimal systematics. The spectrum shows three water emission features (at >6σ confidence) and evidence for optical opacity, possibly due to H−, TiO, and VO (combined significance of 3.8σ). Models that fit the data require a thermal inversion, molecular dissociation as predicted by chemical equilibrium, a solar heavy element abundance ("metallicity", M/H = 1.03+1.11−0.51 × solar), and a carbon-to-oxygen (C/O) ratio less than unity. The data also yield a dayside brightness temperature map, which shows a peak in temperature near the sub-stellar point that decreases steeply and symmetrically with longitude toward the terminators. © 2023, CC BY.

关键词： Molecular oxygen

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