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Research and Development of High Performance Dr yer for Producing High Quality Dried Foods

Japan Journal of Food engineering 2023年第1期24卷 11-18页

作者： Kihara, Yasuhiro Kihara, Toshimasa Kihara, Koichiro Arima, Hideyuki Yamamoto, Shuichi KIHARA WORKS CO. LTD 3106-1 Aio-nishi Yamaguchi Yamaguchi-City754-1102 Japan Yamaguchi Prefectural Industrial Technology Institute 4-1-1 Asutopia Yamaguchi Ube-City755-0195 Japan Graduate School of Science and Innovation and Biomedical Engineering Center Yamaguchi University 2-16-1 Tokiwadai Yamaguchi Ube-City755-8611 Japan

Drying is important for producing long shelf life food products such as vegetables, fruits and liquid foods. A batch hot air tray dr yer is widely used for food dr ying as the equipment is simple and easy to use. The problem of the food dr ying process by such tray dr yers is that it is dif ficult to determine the optimum dr ying program such as air temperature and humidity. A trial and error approach is commonly employed for determining the dr ying program, which is labor intensi ve and time-consuming. Another approach is to use mechanistic or hybrid models along with various monitoring devices, some of which can work as soft sensors. We have developed a laborator y dr ying setup, equipped with non-invasive temperature sensors, humidity sensors, a digital camera and an electronic balance. The weight of the sample, the air temperature, the air humidity, the sample temperature and the sample image can be recorded on-line by PC. A proto-type tray dr yer having above-mentioned devices was also developed. As for the model, a water dif fusion equation along with a heat balance equation considering the mass transfer through the interface was used. It is practically dif ficult to determine the optimum dr ying program (temperature step change) experimentally because a single dr ying experiment takes at least a few hours as high air temperatures cannot be used in order to avoid the quality loss of the food product. It is therefore best to use the model simulation for determining the optimum conditions with the data obtained by the dr yer with various sensing devices. We have demonstrated that the dr yer developed in this study was able to monitor the color change of the model food samples continuously, which might be related to the loss of free amino acid concentrations during the late stage of dr ying. © 2023 Japan Society for Food engineering.

关键词： Drying

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Improving research through mentor and mentee training

Improving research through mentor and mentee training

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2020 ASEE Research Leadership Institute, RLI 2020

作者： Brace, Chris College of Engineering Departments of Radiology and Biomedical Engineering Program

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Implementation of a Fall Prediction System Using Neural Network Algorithms on a Microcontroller

Implementation of a Fall Prediction System Using Neural Netw...

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Consumer Technology (ICCT-Pacific), International Conference on

作者： Yue-Ru Chuang Yu-His Li Wen-Hui Chen En-Ting Kuo Yu-Chieh Lin Jinn-Yuan Lay Department of Electrical Engineering Fu Jen Catholic University New Taipei City Taiwan Department of Electrical Engineering Graduate Institute of Biomedical Engineering National Taiwan University of Science and Technology Taipei City Taiwan WUSA Smart Inc. Taipei City Taiwan

ISBN: (数字)9798331504120

ISBN: (纸本)9798331504137

Based on the needs of hospital rehabilitation centers, this study focuses on posture detection for patients undergoing rehabilitation in hospitals, especially the elderly. The goal is to ensure that nearby medical staff receive alerts as soon as possible when a potential fall is detected, allowing them to intervene before an incident occurs. This paper proposes a fall prediction system that uses sensor fusion and a Feedforward Neural Network (FNN). The system consists of a Bluetooth-enabled microcontroller unit (MCU) integrated with a 6-axis Inertial Measurement Unit (IMU), which is placed on the patient's collar. In this study, the potential movements performed by patients during rehabilitation are classified into nine categories: standing, stomping, stair climbing, stretching, waist twisting, bending over, squatting, walking, and running. Motion data from the IMU is processed using an FNN and k-means clustering for movement classification and abnormal motion detection. If a potential fall is detected, an alarm is sent via Bluetooth to notify nearby medical staff. Finally, the proposed fall prediction system will be implemented on a Bluetooth-enabled MCU module.

关键词： Performance evaluation Microcontrollers Hospitals Sensor fusion Stairs Predictive models Prediction algorithms Real-time systems Feedforward neural networks Wearable devices

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Immigrants’ Experience of Navigating eHealthcare Tools in Canada: A Scoping Review

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Journal of Immigrant and Minority Health 2025年 1-11页

作者： Asbaghi, Yasamin Goertzen, Sonya Houldsworth, Anastasia Monnin, Caroline Choukou, Mohamed-Amine Department of Occupational Therapy University of Manitoba Winnipeg Canada Neil John Maclean Library University of Manitoba Winnipeg Canada Department of Occupational Therapy College of Rehabilitation Sciences Biomedical Engineering Program University of Manitoba Winnipeg Canada

Access to healthcare in Canada is evolving alongside eHealth tools. Despite a growing immigrant population, there’s limited research on their usage of eHealthcare. Occupational therapists in Canada are increasingly involved in supporting and advocating for the accessibility of immigrants to the eHealthcare *** provide an overview of services, barriers, and facilitators within the eHealth navigation experience by immigrants to Canada from the available published literature. A scoping review was conducted to gather academically published and grey literature, available between 2013 and 2024, that pertains to immigrants’ use of eHealth in Canada. An initial search took place in 2023 and was updated in 2024, yielding 296 articles. Thirteen (13) manuscripts were included in the scoping review. Analysis of the results revealed three themes within the literature addressing immigrants’ navigation of eHealth tools: the impact of COVID-19 on mental health, social determinants of eHealth, and online information-seeking behaviours. The analysis of the outcomes from the included studies revealed critical gaps in Canada’s health system that challenge immigrants’ access to eHealth services and recommendations to address these gaps. Collaboration among stakeholders is essential to develop tailored interventions and policies, with occupational therapists positioned to play a crucial role in helping to achieve equitable access to eHealth for immigrants in Canada. More research is needed to inform the creation and integration of culturally sensitive and linguistically accessible eHealth tools in Canada, tailored to meet the needs of immigrants in terms of their cultural background, context, and language.

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Optimized Photonic Integrated Circuit Components for Optical Coherence Tomography at 1060 nm

Optimized Photonic Integrated Circuit Components for Optical...

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Conference on Lasers and Electro-Optics (CLEO)

作者： Senyue Hao Aaron J Adkins Yitian Zhang Chao Zhou Department of Electrical & Systems Engineering Washington University in Saint Louis USA Imaging Science PhD Program Washington University in Saint Louis USA Department of Biomedical Engineering Washington University in Saint Louis USA

To implement optical coherence tomography on photonic chips, we developed optimized and experimentally validated silicon nitride-based components for photonic integrated circuits in order to achieve high sensitivity a... 详细信息

ISBN: (纸本)9798350369311

关键词： Sensitivity Optical coherence tomography Photonic integrated circuits Silicon Electro-optical waveguides Photonics

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Development of a pendulum machine for measuring contact lens friction

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Biosurface and Biotribology 2021年第3期7卷 154-161页

作者： Kiyoshi Mabuchi Hiroko Iwashita Rina Sakai Masanobu Ujihira Yuichi Hori Department of Biomedical Engineering Kitasato University1-15-1KitasatoSagamiharaJapan Graduate School of Medicine Toho University5-21-16OmorinishiOta-kuTokyoJapan

The lubrication ability of a contact lens is one of its most essential properties because high friction on an eyelid causes discomfort during *** measurements allow assessment of lubrication *** far,several apparatuses have been developed to measure contact lens ***,thus far,ocular physiological conditions including sliding speed and area have been imperfectly ***,a pendulum-type friction tester was developed for the assessment of contact lenses under physiological conditions.A high sliding speed of 90 mm/s was achieved thanks to the short oscillation period of the small ***,the sliding surface on a contact lens was realised at the fulcrum of the *** coefficient of friction for the interaction between a contact lens and plastic hemisphere was directly calculated from the decay in potential energy during the free libration of the *** coefficient of a commercially available contact lens in saline solution,0.1%and 0.3%HA solutions were 0.036,0.039 and 0.050,*** results were reliable because they ranged within the low levels reported by previous *** was shown that the present pendulum machine represents a major advancement in the realisation of physiologically realistic contact lens friction measurement.

关键词： linking apparatus oscillation

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Continuous Zif-8 Film Formation Through Consecutive Seed Layer Overlaying

SSRN

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SSRN 2023年

作者： Yoo, Hoyeon Shin, Naechul Program in Biomedical Science and Engineering Inha University Incheon22212 Korea Republic of Program in Smart Digital Engineering Inha University Incheon22212 Korea Republic of Department of Chemical Engineering Inha University Incheon22212 Korea Republic of

The fabrication of pinhole-free and well-intergrown metal-organic frameworks (MOFs) in film morphology is crucial for various applications such as gas separation and sensing, as it necessitates uniform and controlled mass transport and sorption at the internal pore surfaces. In this work, we report the growth of continuous zeolitic imidazolate framework-8 (ZIF-8) thin films via a secondary growth method using a consecutive ZnO seed layer overlaying approach. The primary growth of ZIF-8 crystals on planar substrates occurs through heterogeneous nucleation, followed by overlaying ZnO seed layers via radio frequency (RF) sputtering for secondary growth. We systematically investigate the morphology, crystallinity, and surface properties of the resulting ZIF-8 films. Our results confirm that the seed layer overlaying induces core-shell-like epitaxial growth on the primary ZIF-8 crystals, promoting conformal growth and interconnection between isolated islands. These findings demonstrate a promising method for synthesizing continuous, pinhole-free MOF films with various compositions and porosities for numerous applications. © 2023, The Authors. All rights reserved.

关键词： Zinc oxide

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Global distortions from local rewards: neural coding strategies in path-integrating neural systems 24

Global distortions from local rewards: neural coding strateg...

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Proceedings of the 38th International Conference on Neural Information Processing Systems

作者： Francisco Acosta Fatih Dinc William T. Redman Manu Madhav David Klindt Nina Miolane Department of Physics UC Santa Barbara CNC Program Stanford University Applied Physics Laboratory Johns Hopkins University Biomedical Engineering University of British Columbia NeuroAI CSHL Electrical & Computer Engineering UC Santa Barbara

ISBN: (纸本)9798331314385

Grid cells in the mammalian brain are fundamental to spatial navigation, and therefore crucial to how animals perceive and interact with their environment. Traditionally, grid cells are thought support path integration through highly symmetric hexagonal lattice firing patterns. However, recent findings show that their firing patterns become distorted in the presence of significant spatial landmarks such as rewarded locations. This introduces a novel perspective of dynamic, subjective, and action-relevant interactions between spatial representations and environmental cues. Here, we propose a practical and theoretical framework to quantify and explain these interactions. To this end, we train path-integrating recurrent neural networks (piRNNs) on a spatial navigation task, whose goal is to predict the agent's position with a special focus on rewarded locations. Grid-like neurons naturally emerge from the training of piRNNs, which allows us to investigate how the two aspects of the task, space and reward, are integrated in their firing patterns. We find that geometry, but not topology, of the grid cell population code becomes distorted. Surprisingly, these distortions are global in the firing patterns of the grid cells despite local changes in the reward. Our results indicate that after training with location-specific reward information, the preserved representational topology supports successful path integration, whereas the emergent heterogeneity in individual responses due to global distortions may encode dynamically changing environmental cues. By bridging the gap between computational models and the biological reality of spatial navigation under reward information, we offer new insights into how neural systems prioritize environmental landmarks in their spatial navigation code.

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Direct Interaction between the Transmembrane Helices Stabilize Cytochrome P450 2b4 and Cytochrome B5 Redox Complex

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SSRN 2023年

作者： Ramamoorthy, Ayyalusamy Sahoo, Bikash R. Biophysics Program Department of Chemistry Macromolecular Science and Engineering Biomedical Engineering Michigan Neuroscience Institute The University of Michigan Ann ArborMI48109-1055 United States

The catalytic activity of cytochrome P450 2B4 (CYP2B4) is moderated by its cognate redox partner cytochrome b5 (Cyt-b5). The endoplasmic reticulum (ER) membrane and intermolecular transmembrane (TM) interaction between CYP2B4 and Cyt-b5 regulate the substrate catalysis and the reaction rate. This emphasizes the significance of elucidating the molecular basis of CYP2B4 and Cyt-b5 complexation in a membrane environment to better understand the enzymatic activity of CYP2B4. Our previous solid-state NMR studies revealed the membrane topology of the transmembrane domains of these proteins in the free and complex forms. Here, we show the cross-angle complex formation by the single-pass TM domains of CYP2B4 and Cyt-b5, which is mainly driven by several salt-bridges (E2-R128, R21-D104 and K25-D104), using a multimicrosecond molecular dynamic simulation. Additionally, the leucine-zipper residues (L8, L12, L15, L18 and L19 from CYP2B4) and π-stacking between H23 and F20 residues of CYP2B4 and W110 of Cyt-b5 are identified to stabilize the TM-TM complex in the ER membrane. The simulated tilts of the helices in the free and in the complex are in excellent agreement with solid-state NMR results. The TM-TM packing influences a higher order structural stability when compared to the complex formed by the truncated soluble domains of these two proteins. MM/PBSA based binding free energy estimates nearly 100-fold higher binding affinity (ΔG=-2810.68±696.44 kJ/mol) between the soluble domains of the full-length CYP2B4 and Cyt-b5 when embedded in lipid membrane as compared to the TM-domain-truncated soluble domains (ΔG=-27.406±10.32 kJ/mol). The high-resolution full-length CYP2B4-Cyt-b5 complex structure and its dynamics in a native ER membrane environment reported here could aid in the development of approaches to effectively modulate the drug-metabolism activity of CYP2B4. © 2023, The Authors. All rights reserved.

关键词： Lipid bilayers

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Z-Laminating Assembly of Graphene Nanoflakes for Super-Strong Membranes and Functional Coatings

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ACS Applied Nano Materials 2024年第13期7卷 14957-14963页

作者： Santos, Ian Daniell Tjarks, Patrick Muthu, Jeyavelan Lin, You-Chen Yen, Zhi-Long Chand, Pradyumna Kumar Raman, Radha Nguyen, Dinh Tuan Rouhani, Mehdi Jeng, Yeau-Ren Hsieh, Ya-Ping Hofmann, Mario Department of Physics National Taiwan University Taipei 106 Taiwan Nano Science and Technology Program Taiwan International Graduate Program Academia Sinica and National Taiwan University Taipei 106 Taiwan J. Heyrovsky Institute of Physical Chemistry of the Czech Academy of Sciences Prague 18200 Czech Republic Institute of Atomic and Molecular Sciences Academia Sinica Taipei 106 Taiwan Department of Chemistry National Taiwan University Taipei 106 Taiwan Department of Physics National Central University Taoyuan 320 Taiwan Molecular Science and Technology Program Taiwan International Graduate Program Academia Sinica and National Central University Taipei 106 Taiwan Department of Biomedical Engineering National Cheng Kung University 1 University Road Tainan 70101 Taiwan Department of Materials Science and Engineering National Cheng Kung University Tainan 70101 Taiwan Academy of Innovative Semiconductor and Sustainable Manufacturing National Cheng-Kung University (NCKU) Tainan 70101 Taiwan

We demonstrate the strengthening of graphene, an atomically thin carbon allotrope, by out-of-plane folding. Through lateral confinement of graphene at the water-air interface, nanoscale buckling was induced in suspended flakes, leading to an unexpected folding transition beyond a critical surface pressure. The emergence of folding was confirmed by in situ Brewster angle reflectivity and ex situ microscopy, showing a unique “z-laminated” nanostructure. Molecular dynamics simulations indicate that z-lamination yields an enhanced adhesion between neighboring flakes compared to lateral sliding, which was confirmed by a surface pressure hysteresis during the folding process. Mechanical testing reveals superior Young’s modulus and yield strength when compared to conventional graphene assemblies and even compared to composites. We demonstrate the potential of the z-lamination approach for applications in graphene-based structural materials, tribological layers, and functional electrochemical coatings. Finally, the complete recyclability of z-laminated graphene opens up new routes toward sustainable nanostructured materials. © 2024 The Authors. Published by American Chemical Society

关键词： 2D materials composites laminated graphene membranes recyclable

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