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TrinityMag:A novel magnetically actuated miniature robot manipulating system with a human-scale workspace

Science China(Technological Sciences) 2024年第11期67卷 3546-3558页

作者： LI Dong CHEN BinHan HUANG ChenYang XU Sheng WU XinYu XU TianTian Guangdong Provincial Key Laboratory of Robotics and Intelligent System Shenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Key Laboratory of Biomedical Imaging Science and System Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

The development of the magnetic manipulating system is essential for applications of magnetically actuated miniature robots in biomedical practice,such as targeted therapy and precise ***,the workspaces of existing magnetic manipulating systems for miniature robots are mostly insufficient to manipulate miniature robots inside human *** present study proposes an innovative electromagnets-based manipulating system,TrinityMag,which can produce dynamic three-dimensional(3D)magnetic fields in a human-scale spherical workspace with a 2.6 m *** magnetic field of a single electromagnet is simulated,and a new calibration technic is designed based on deep learning ***,the arrangement of three electromagnets is optimized to produce maximal 3D arbitrary magnetic fields with limited ***,a target-tracking algorithm is developed so that the TrinityMag can track the miniature robot in real ***,the TrinityMag is validated in experiments to manipulate a soft millirobot to move in human-scale tortuous tracks with two types of *** maximum speed of the soft millirobot reaches 11.05 body length/*** work contributes to a significant increment in the workspace of the electromagnets-based manipulating system for miniature *** further expect that the TrinityMag could push the applications of miniature robots from laboratory to clinical practice.

关键词： magnetic manipulating system human-scale workspace magnetically actuated miniature robots

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Assistive robots for Beijing Winter Paralympic torch relay: Accessible technologies to restore human functionality

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The Innovation 2024年第1期5卷 19-20页

作者： Bi Zhang Mei Shuai Bicheng Han Shuo Li Lianqing Liu Xingang Zhao State Key Laboratory of Robotics Shenyang Institute of AutomationCASShenyang 110016China Institutes for Robotics and Intelligent Manufacturing CASShenyang 110169China Department of Biomedical Engineering Beihang UniversityBeijing 100191China Beijing AI-Robotics Technology Co. Ltd.Beijing 100176China Zhejiang BrainCo Technology Co. Ltd.Hangzhou 311121China

The success of the Beijing Winter Olympics and Paralympics epitomized the vision of a community with a shared future for *** robots and artificial intelligence technologies were used in various games and events,such as assisting in parades,logistics,and security *** integration of unmanned robotic systems into torch relays was one of the highlights of the Winter Olympics.

关键词： Winter Access artificial

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Thermal and Magnetic Dual-Responsive Catheter-Assisted Shape Memory Microrobots for Multistage Vascular Embolization

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Research 2024年第3期2024卷 529-543页

作者： Qianbi Peng Shu Wang Jianguo Han Chenyang Huang Hengyuan Yu Dong Li Ming Qiu Si Cheng Chong Wu Mingxue Cai Shixiong Fu Binghan Chen Xinyu Wu Shiwei Du Tiantian Xu Guangdong Provincial Key Lab of Robotics and Intelligent Systems Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenChina University of Chinese Academy of Sciences BeijingChina Department of Neurosurgery South China HospitalMedical SchoolShenzhen University.ShenzhenChina The Key Laboratory of Biomedical Imaging Science and System Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenChina.

Catheters navigating through complex vessels,such as sharp turns or multiple U-turns,remain challenging for vascular ***,we propose a novel multistage vascular embolization strategy for hard-to-reach vessels that releases untethered swimming shape-memory magnetic microrobots(SMMs)from the prior catheter to the vessel ***,made of organo-gel with magnetic particles,ensure biocompatibility,radiopacity,thrombosis,and fast thermal and magnetic *** SMM is initially a linear shape with a 0.5-mm diameter at 20°C inserted in a *** transforms into a predetermined helix within 2 s at 38°C blood temperature after being pushed out of the catheter into the *** enable agile swimming in confined and tortuous vessels and can swim upstream using helical propulsion with rotating magnetic ***,we validated this multistage vascular embolization in living rabbits,completing 100-cm travel and renal artery embolization in 2 *** 4 weeks,the SMMs maintained the embolic position,and the kidney volume decreased by 36%.

关键词： turns maintained travel

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Acoustic black hole effect enhanced micromanipulator

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Microsystems & Nanoengineering 2024年第5期10卷 345-352页

作者： Qiu Yin Haoyong Song Zhaolong Wang Zhichao Ma Wenming Zhang State Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong UniversityShanghaiChina institute of Medical Robotics School of Biomedical EngineeringShanghai Jiao Tong UniversityShanghaiChina College of Mechanical and Vehicle Engineering Hunan UniversityChangshaChina School of Energy Science and Engineering Harbin Institute of TechnologyHarbinP.R.China

Microparticle manipulation is a critical concern across various felds including microfabrication,flexible electronics and tissue ***-activated sharp structures have been designed as simple and flexible tools to manipulate microparticles with their good compatibility,fast response,and broad ***,there still lacks rational acoustic-structure design for effective energy concentration at the acoustic-activated sharp structures for microparticle ***,we present the acoustic black hole(ABH)effect as enhancement for the acoustic *** provides great reliability,simplicity and ease of use,supporting custom design of high-throughput patterning ***,compared to commonly used configurations,such as cylindrical or conical microneedles,those microneedles with ABH profle exhibit superior acoustic energy focusing at the tip and induce stronger acoustofluidic *** average acoustic flow velocity induced by the ABH microneedle is 154 times greater than that of the conical one and 45 times greater than that of the cylindrical ***,the average acoustic radiation force(ARF)produced by the ABH microneedle against acrylic microparticles is about 319 times greater than that of the cylindrical one and 16 times greater than that of the conical *** results indicate that ABH design significantly enhances microparticle *** demonstrate this concept with ABH effect enhanced microparticle manipulation and study the parameters influencing its performance including operating frequency,operating voltage and particle ***,considering the flexibility of this system,we employ it for various patterning and high-throughput microparticle *** work paves the way for controllable microparticle manipulation,holding great potential for applications in microfabrication and biomedicine.

关键词： cylindrical Acoustic simplicity

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Quantifying Joint Movement Variability in Healthy and Hemiplegic Gait using OpenSim 2

Quantifying Joint Movement Variability in Healthy and Hemipl...

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2nd IEEE International Conference on Interdisciplinary Approaches in technology and Management for Social Innovation, IATMSI 2024

作者： Rafiq, Tabassum Younis, Sadia Narayan, Jyotindra Institute of Information Management and Technology Department of Biotechnology Uttar Pradesh Aligarh202001 India Government College of Engineering and Technology Department of Biomedical Engineering Jammu and Kashmir Ganderbal193504 India Indian Institute of Technology Guwahati Mechatronics and Robotics Laboratory Department of Mechanical Engineering Assam Guwahati781039 India

ISBN: (纸本)9798350360523

This study delves into the scaling capabilities of OpenSim, a biomechanical modeling tool, to scrutinize musculoskeletal alterations accompanying the hemiplegic condition compared to a healthy model. Contralateral hemiplegia (CH), characterized by unilateral paralysis, induces profound changes in bone size and significantly influences an individual's gait. Motivated by understanding the biomechanical repercussions of CH on human movement, we conducted a comprehensive investigation involving ten patients with CH, with a median age of 46 years (range: 39 to 52.0 years and height: 1.75 0.6 m). Ten healthy controls with similar body attributes were±also recruited. We assessed musculoskeletal changes post-CH using bone length data from MRI reports obtained from a hospital. Inverse kinematics in OpenSim are facilitated for a detailed comparison of joint angles between unhealthy and healthy individuals. The gait data is visualized and analyzed using statistical metrics such as mean absolute deviation, box plots, and a two-sample t-test. The results revealed significant differences in hip and ankle joint angles between healthy and hemiplegic individuals, underscored by low p-values. Interestingly, no significant difference was observed in knee joint angles (p-value = 0.9126). These findings contribute to a valuable understanding of hemiplegia-related musculoskeletal changes, offering potential avenues for tailored interventions to improve mobility and quality of life. © 2024 IEEE.

关键词： Inverse kinematics

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Electrochemical Monitoring of Intracellular Reactive Oxygen Species Based on Automated Nanoprobe Platform

Electrochemical Monitoring of Intracellular Reactive Oxygen ...

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2023 Annual IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2023

作者： Ma, Yanmei Hu, Weikang Ruan, Muyang Zhan, Zhen Zhang, Yi Hu, Chengzhi Southern University of Science and Technology Shenzhen Key Laboratory of Biomimetic Robotics and Intelligent Systems Department of Mechanical and Energy Engineering Shenzhen China City University of HongKong Department of Biomedical Engineering Hong Kong

ISBN: (纸本)9798350344486

The electrochemical detection of endogenous molecules from a single cell is a crucial technique for understanding fundamental cellular processes at the subcellular level and uncovering cellular heterogeneity. However, high throughput intracellular detection has posed significant challenges. This paper proposes a simple method for fabricating a nanoprobe for the electrochemical monitoring of intracellular reactive oxygen species (ROS), which are important signaling molecules that play a key role in a wide range of cellular processes, including apoptosis, proliferation, and differentiation. Combined with the automated nanoprobe platform, the study successfully achieved minimally invasive and efficient intracellular ROS detection in living cells. Moreover, the results reveal that the average ROS concentration in the cytoplasm and nucleus is uneven, which has important implications for the understanding of cellular redox signaling. © 2023 IEEE.

关键词： Nanoprobes

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Research on optical properties of human hepatoma cells using terahertz time-domain spectroscopy

Research on optical properties of human hepatoma cells using...

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2023 International Symposium on Ultrafast Phenomena and Terahertz Waves, ISUPTW 2023

作者： Guan, Hanxiao Qiu, Weihang Ma, Yehao Tian, Liangfei Cao, Yuqi Zhang, Guangxin College of Control Science and Engineering Zhejiang University State Key Laboratory of Industrial Control Technology Hangzhou China Zhejiang University College of Biomedical Engineering and Instrument Science Hangzhou China Ningbo University of Technology Robotics Institute Ningbo China

ISBN: (纸本)9798350317473

Terahertz technology is a non-invasive and label-free inspection method, promising for applications in various fields, especially in biomedical diagnosis. Terahertz radiation is capable for cell physiological and pathological status recognition due to its sensitivity to cell composition and structural information of biomacromolecular. In this paper, the transmission properties of glass, polymethyl methacrylate and polypropylene in THz regime were compared and polypropylene was selected as the petri dish material for cell adhesion due to its high transmission of terahertz wave. The time-domain and frequency-domain spectra, refractive index and absorption coefficient of hepatoma cell line Huh7 and normal cell line MIHA were analyzed. The experimental results showed significant distinction between the terahertz characteristic spectra of hepatoma cells and normal cells. This work can be helpful for applying terahertz technology in cancer detection at the cellular level. © 2023 IEEE.

关键词： Terahertz waves

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Suppression of thermal transport in bent boron arsenide nanoribbons

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Physical Review Applied 2024年第5期22卷 054019页

作者： Guanbo Jiao Shuo Qiao Jun Lyu Yi Tao Lin Yang Department of Advanced Manufacturing and Robotics College of Engineering School of Mechanical Engineering and Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments National Key Laboratory of Advanced Micro and Nano Manufacture Technology

Boron arsenide (BAs) has emerged as a strong contender for next-generation functional materials, boasting desirable attributes such as high thermal conductivity and ambipolar mobility. However, a critical yet underexplored challenge lies in understanding its heat conduction capabilities under inhomogeneous strain, which is pivotal across various functional devices and operational conditions. Here, through modeling thermal transport in bent BAs and Si nanoribbons, a striking difference is revealed. Namely, the BAs nanoribbons exhibit nearly twice the reduction in thermal conductivity compared with Si under identical bending conditions. This significant disparity is driven by two key factors: the pronounced effect of phonon-spectra broadening under strain and the inhomogeneous strain-induced narrowing of the acoustic and optical (ao) gap. Together, these factors relax the originally restricted phonon scattering phase space and fundamentally alter phonon scattering dynamics. Our findings not only offer a new perspective on how heat transfer can be dynamically modulated in BAs, but also provide crucial insights into enhancing thermal performance in BAs-based functional devices.

关键词： Anharmonic lattice dynamics Bending Heat transfer Phonons Strain Thermal conductivity Nanoribbon Molecular dynamics

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High-precision Calibration of Camera and IMU on Manipulator for Bio-inspired Robotic System

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Journal of Bionic Engineering 2022年第2期19卷 299-313页

作者： Yinlong Zhang Wei Liang Sichao Zhang Xudong Yuan Xiaofang Xia Jindong Tan Zhibo Pang State Key Laboratory of Robotics Shenyang Institute of AutomationChinese Academy of SciencesShenyang 110016China Key Laboratory of Networked Control Systems Chinese Academy of SciencesShenyang 110016China Institutes for Robotics and Intelligent Manufacturing Chinese Academy of SciencesShenyang 110169China The School of Computer Science and Technology Xidian UniversityXi’an 710071China Department of Mechanical Aerospace and Biomedical EngineeringUniversity of TennesseeKonxville 37996USA Department of Automation Technology ABB Corporate Research Sweden72178 VästerasSweden

Inspired by box jellyfish that has distributed and complementary perceptive system,we seek to equip manipulator with a camera and an Inertial Measurement Unit(IMU)to perceive ego motion and surrounding unstructured *** robot perception,a reliable and high-precision calibration between camera,IMU and manipulator is a critical *** paper introduces a novel calibration ***,we seek to correlate the spatial relationship between the sensing units and manipulator in a joint ***,the manipulator moving trajectory is elaborately designed in a spiral pattern that enables full excitations on yaw-pitch-roll rotations and x-y-z translations in a repeatable and consistent *** calibration has been evaluated on our collected visual inertial-manipulator *** systematic comparisons and analysis indicate the consistency,precision and effectiveness of our proposed calibration method.

关键词： Bio-inspired robotic system Monocular camera IMU Manipulator Calibration

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Fin-Wave-Inspired Wireless Small-Scale Soft Robot for Adaptive Amphibious Locomotion Under Single-Mode Magnetic Field

Fin-Wave-Inspired Wireless Small-Scale Soft Robot for Adapti...

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International Conference on Manipulation, Automation and robotics at Small Scales (MARSS)

作者： Chen Wang Sarthak Misra Venkatasubramanian Kalpathy Venkiteswaran Department of Biomaterials and Biomedical Technology Surgical Robotics Laboratory University of Groningen and University Medical Centre Groningen Groningen The Netherlands Department of Biomechanical Engineering Surgical Robotics Laboratory University of Twente Enschede The Netherlands

ISBN: (数字)9798350376807

ISBN: (纸本)9798350376814

Magnetic soft robots are capable of generating programmable deformation based on variable magnetization profiles, with the added potential advantages of easy fabrication and miniaturization. However, achieving efficient locomotion and maneuverability in complex and variable environments often requires intricate modulation of external magnetic field which limits their applications. Inspired by the undulating fin-wave often seen in aquatic organisms, this paper demonstrates a small-scale soft robot capable of adaptive amphibious locomotion under a rotating magnetic field, allowing the robot to efficiently move on the solid surface (dry) and in liquids (wet). The robot comprises of a combination of multiple soft rod-shaped legs (6 × 1 ×1 mm) with different magnetization directions capable of generating undulating waves. Simulation of the undulating wave is conducted based on Cosserat rod theory to aid in the design and arrangement of the legs. The maneuverability and capability of steering and transitioning from dry to wet surfaces as well as sinking and floating in hybrid environments are demonstrated. The robot's ability to move with and against the flow of liquid in pipes of variable diameter is studied and characterized. The results demonstrate the potential to use as a small-sized wireless robot in applications, such as navigating within human blood vessels for clinical interventions.

关键词： Legged locomotion Wireless communication Surface waves Magnetization Magnetic liquids Soft robotics Solids

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