检索结果-内蒙古大学图书馆

IEEE Conference on Decision and Control

作者： Brenner S. Rego Guilherme V. Raffo Marco H. Terra Joseph K. Scott Department of Chemical and Biomolecular Engineering Georgia Institute of Technology 311 Ferst Dr. Atlanta GA USA Department of Electrical and Computer Engineering University of Säo Paulo Säo Carlos SP Brazil Department of Electronics Engineering and the Graduate Program in Electrical Engineering Federal University of Minas Gerais Belo Horizonte MG Brazil

ISBN: (数字)9798350316339

ISBN: (纸本)9798350316346

This paper presents a novel algorithm for reachability analysis of nonlinear discrete-time systems. The proposed method combines constrained zonotopes (CZs) with polyhedral relaxations of factorable representations of nonlinear functions to propagate CZs through nonlinear functions, which is normally done using conservative linearization techniques. The new propagation method provides better approximations than those resulting from linearization procedures, leading to significant improvements in the computation of reachable sets in comparison to other CZ methods from the literature. Numerical examples highlight the advantages of the proposed algorithm.

关键词： Discrete-time systems Linearization techniques Approximation algorithms Complexity theory Reachability analysis

来源：评论

学校读者我要写书评

暂无评论

Efficient Separation of Carbon Dioxide and Methane in High-Pressure and Wet Gas Mixtures Using Zr-Mof-808

SSRN

引用

SSRN 2024年

作者： Menezes, Tamires R. Santos, Kátilla M.C. Mao, Haiyan Santos, Klebson De Conto, Juliana F. Reimer, Jeffrey A. Dariva, Silvia M.E. Santana, Cesar C. Laboratory of Materials Synthesis and Chromatography Institute of Technology and Research SE Aracaju49032-490 Brazil Graduate Program in Process Engineering Tiradentes University SE Aracaju49032-490 Brazil Department of Chemical and Biomolecular Engineering University of California Berkeley BerkeleyCA94720 United States

Due to global warming, the capture and separation of CO2 has been the focus of a plethora of research in order to mitigate its emissions and contribute to global development. Given that CO2 is commonly found in natural gas currents, there have been efforts to seek more efficient materials to separate gaseous mixtures such as CO2/CH4. However, there are only a few reports in regards to adsorption processes within pressurized systems. In the offshore scenario, natural gas currents still exhibit high moisture content, necessitating a greater understanding of processes in moist systems. In this article, a metal-organic framework synthesis based on zirconium (MOF-808) was carried out through a conventional solvothermal method and autoclave for the adsorption of CO2 and CH4 under different temperatures (45 °C to 65 °C) and pressures ranging from 50 to 100 bar. Furthermore, the adsorption of humid CO2 was evaluated using thermal analyses. The MOF-808 synthesized in autoclave showed a high surface area (1502 m2 g-1 per BET) and a high porosity volume (0.63 cm3 g-1 per DFT). As for the MOF-808 conventionally synthesized, though presenting a high crystallinity, it showed a lesser superficial area (1323 m2 g-1 per BET) and a lower volume of pores (0.51 cm3 g-1 per DFT) in relation to the one synthesized in the autoclave. Also, the MOF-808 synthesized in the autoclave showed a high capacity for CO2 adsorption at 50 bar and 45°C and had a low selectivity to capture CH4 molecules. It also exhibited a fine stability after five cycles of CO2 adsorption and desorption at 50 bar and 45 °C - as confirmed by structural post-adsorption analyses while maintaining its adsorption capacity and crystallinity. Furthermore, it can be observed that the adsorption capacity increased in a humid environment, and the adsorbent remained stable after adsorption cycles in the presence of moisture. Finally, it was possible to confirm the occurrence of physisorption processes through NMR analyses, valid

关键词： Carbon dioxide

来源：评论

学校读者我要写书评

暂无评论

Structural evaluation of Poly(lactic acid) degradation at standardized composting temperature of 58 degrees

引用

Chemosphere 2024年 354卷 141729页

作者： Oh, Jiwon Park, Sung Bae Cha, Chaenyung Hwang, Dong Ki Park, Seul-A Park, Jeyoung Oh, Dongyeop X. Jeon, Hyeonyeol Koo, Jun Mo Ulsan44429 Korea Republic of Ulsan44919 Korea Republic of Pohang37673 Korea Republic of Department of Chemical and Biomolecular Engineering Sogang University Seoul04107 Korea Republic of Department of Polymer Science and Engineering and Program in Environmental and Polymer Engineering Inha University Incheon22212 Korea Republic of Daejeon34113 Korea Republic of Department of Organic Materials Engineering Chungnam National University Daejeon34134 Korea Republic of

The accumulation of petroleum-based plastics on our planet is causing serious environmental pollution. Biodegradable plastics, promoted as eco-friendly solutions, hold the potential to address this issue. However, their impact on the environment and the mechanisms of their natural degradation remain inadequately understood. Furthermore, the specific conditions set forth in international standards for evaluating the biodegradability of biodegradable plastics have led to misconceptions about their real-world behavior. To properly elucidate the relationship between their degradability and structure, this study mimics the thermal effect on poly(lactic acid) (PLA) under standardized composting temperature. The higher the crystallinity of PLA, the lower the degradation rate, which suggests that crystallinity is a key factor in determining degradation. The composting temperature of 58 °C induces crystallization by having a structural effect on the polymer, which in turn reduces the degradation rate of PLA. Therefore, control over temperature and crystallization during the processing and degradation of PLA is crucial, as it not only determines the biodegradability but also enhances the utility. © 2024

关键词： Biodegradability

来源：评论

学校读者我要写书评

暂无评论

pH/GSH dual responsive nanosystem for nitric oxide generation enhanced type I photodynamic therapy

引用

Bioactive Materials 2024年第4期34卷 414-421页

作者： Jianhua Zou Zheng Li Yang Zhu Yucen Tao Qing You Fangfang Cao Qinghe Wu Min Wu Junjie Cheng Jianwei Zhu Xiaoyuan Chen Departments of Diagnostic Radiology SurgeryChemical and Biomolecular Engineeringand Biomedical EngineeringYong Loo Lin School of Medicine and College of Design and EngineeringNational University of SingaporeSingapore119074Singapore Nanomedicine Translational Research Program NUS Center for NanomedicineYong Loo Lin School of MedicineNational University of SingaporeSingapore117597Singapore Clinical Imaging Research Centre Centre for Translational MedicineYong Loo Lin School of MedicineNational University of SingaporeSingapore117599Singapore Institute of Molecular and Cell Biology Agency for ScienceTechnologyand Research(A*STAR)61 Biopolis DriveProteosSingapore138673Singapore Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai Jiaotong UniversityShanghai200011PR China Department of Chemistry Center for Bioanalytical Chemistry University of Science and Technology of ChinaHefei230026PR China College of Life Science Nanjing Normal University1 Wenyuan RoadNanjing210023PR China

Tumor hypoxia diminishes the effectiveness of traditional type II photodynamic therapy(PDT)due to oxygen *** I PDT,which can operate independently of oxygen,is a viable option for treating hypoxic *** this study,we have designed and synthesized JSK@PEG-IR820 NPs that are responsive to the tumor microenvironment(TME)to enhance type I PDT through glutathione(GSH)*** approach aims to expand the sources of therapeutic benefits by promoting the generation of superoxide radicals(O_(2)^(-).)while minimizing their *** diisopropyl group within PEG-IR820 serves a dual purpose:it functions as a pH sensor for the disassembly of the NPs to release JSK and enhances intermolecular electron transfer to IR820,facilitating efficient O_(2)^(-).***,the release of JSK leads to GSH depletion,resulting in the generation of nitric oxide(NO).This,in turn,contributes to the formation of highly cytotoxic peroxynitrite(ONOO^(-).),thereby enhancing the therapeutic efficacy of these ***-II fluorescence imaging guided therapy has achieved successful tumor eradication with the assistance of laser therapy.

关键词： TME responsive NO gas therapy NIR-II imaging Type I PDT

来源：评论

学校读者我要写书评

暂无评论

Importance of Standardizing Analytical Characterization Methodology for Improved Reliability of the Nanomedicine Literature

引用

Nano-Micro Letters 2022年第11期14卷 18-32页

作者： Shahriar Sharifi Nouf N.Mahmoud Elizabeth Voke Markita P.Landry Morteza Mahmoudi Department of Radiology and Precision Health Program Michigan State UniversityEast LansingMIUSA Faculty of Pharmacy Al-Zaytoonah University of JordanAmman 11733Jordan Department of Biomedical Sciences College of Health SciencesQU HealthQatar University2713 DohaQatar Department of Chemical and Biomolecular Engineering University of CaliforniaBerkeleyBerkeleyCAUSA Innovative Genomics Institute BerkeleyCAUSA California Institute for Quantitative Biosciences University of CaliforniaBerkeleyCAUSA Chan Zuckerberg Biohub San FranciscoCAUSA

Understanding the interaction between biological structures and nanoscale technologies,dubbed the nano-bio interface,is required for successful development of safe and efficient nanomedicine *** lack of a universal reporting system and decentralized methodologies for nanomaterial characterization have resulted in a low degree of reliability and reproducibility in the nanomedicine *** such,there is a strong need to establish a characterization system to support the reproducibility of nanoscience data particularly for studies seeking clinical ***,we discuss the existing key standards for addressing robust characterization of nanomaterials based on their intended use in medical devices or as *** also discuss the challenges surrounding implementation of such standard protocols and their implication for translation of nanotechnology into clinical ***,however,emphasize that practical implementation of standard protocols in experimental laboratories requires long-term planning through integration of stakeholders including institutions and funding agencies.

关键词： Characterization Nanomedicine Standard protocols Reproducibility Nanomedicine devices

来源：评论

学校读者我要写书评

暂无评论

Anti-Termite Activity of Azadirachta excelsa Seed Kernel and Its Isolated Compound against Coptotermes curvignathus

Journal of the Korean Wood Science and Technology

引用

Journal of the Korean Wood Science and Technology 2023年第3期51卷 157-172页

作者： Adfa, Morina Wiradimafan, Khafit Pratama, Ricky Febri Sanjaya, Angga Triawan, Deni Agus Yudha S., Salprima Ninomiya, Masayuki Rafi, Mohamad Koketsu, Mamoru Department of Chemistry Faculty of Mathematics and Natural Sciences University of Bengkulu Bengkulu38371 Indonesia Research Center of Sumatera Natural Product and Functional Materials University of Bengkulu Bengkulu38371 Indonesia Master of Chemistry Study Program Faculty of Mathematics and Natural Sciences University of Bengkulu Bengkulu38371 Indonesia Department of Chemistry and Biomolecular Science Faculty of Engineering Gifu University Gifu5011193 Japan Department of Chemistry Faculty of Mathematics and Natural Sciences IPB University Bogor16128 Indonesia Tropical Biopharmaca Research Center-Institute of Research and Community Services IPB University Bogor16128 Indonesia

Azadirachta excelsa, is a plant belonging to the same genus as Indian neem (Azadirachta indica), and its use as a pesticide is reported by few studies. Despite being a different species, it is expected to have the same biopesticide potential as A. indica. Therefore, this study aims to investigate the anti-termite activity of n-hexane and methanol extracts of A. excelsa seed kernel at various concentrations against Coptotermes curvignathus. The methanol extract demonstrated greater termicidal activity than n-hexane at doses test of 2%, 4%, and 8%. It also showed 100% termite mortality on the third day of administering the 8% dose. According to the gas chromatography with mass spectrometry data, the putative main components of the n-hexane extract were hexadecanoic acid, ethyl ester (18.99%), 9,12-octadecadienoic acid (Z,Z)-(16.31%), and 9-octadecenal (16.23%). In contrast, the principal constituents of methanol extract were patchouli alcohol (28.1%), delta-guaiene (15.15%), and alpha-guaiene (11.93%). Furthermore, limonoids profiling of A. excelsa methanol extract was determined using Ultrahigh-performance liquid chromatography coupled with quadrupole-Orbitrap high-resolution mass spectrometry. The number of limonoids identified tentatively was fifteen, such as 6-deacetylnimbin, nimbolidin C, nimbolide, 6-acetylnimbandiol, 6-deacetyl-nimbinene, salannol, 28-deoxonimbolide, gedunin, nimbandiol, epoxyazadiradione, azadirone, 2',3'-dihydrosalannin, marrangin, nimbocinol, and azadirachtin. They were the same as those reported in the seed and leaves of A. indica, but its largest component in A. excelsa was 6-deacetylnimbin. As a result, the presence of these compounds may be responsible for the anti-termite activity of A. excelsa seed kernel extract. Additionally, column chromatography of methanol extract yielded 6-deacetylnimbin, which was found to be antifeedant and termiticide against C. curvignathus. © 2023 The Korean Society of Wood Science & Technology.

关键词： Mass spectrometry

来源：评论

学校读者我要写书评

暂无评论

Advances in AAV capsid engineering: Integrating rational design, directed evolution and machine learning

引用

Molecular Therapy 2025年第5期33卷 1937-1945页

作者： Nisanov, Alan M. Rivera de Jesús, Julio A. Schaffer, David V. Department of Chemistry University of California Berkeley Berkeley 94720 CA United States Department of Chemical and Biomolecular Engineering University of California Berkeley Berkeley 94720 CA United States Department of Bioengineering University of California Berkeley Berkeley 94720 CA United States Graduate Program in Bioengineering University of California Berkeley San Francisco and University of California Berkeley 94720 CA United States Department of Neurological Surgery University of California San Francisco 94143 CA United States Department of Molecular and Cell Biology University of California Berkeley Berkeley 94720 CA United States

Adeno-associated virus (AAV) has emerged as a highly promising vector for human gene therapy due to its favorable safety profile, versatility, and ability to transduce a wide range of tissues. However, natural AAV serotypes have shortcomings, including suboptimal transduction efficiency, pre-existing immunity, and a lack of tissue specificity, that hinder their therapeutic potential. To address these challenges, significant efforts are being applied to engineer novel AAV capsids. Rational design leverages structural insights to enhance capsid properties, directed evolution enables unbiased selection of superior variants, and machine learning accelerates discovery by computational analysis of high-throughput screening results to enable predictive algorithms. These strategies have yielded novel capsids with improved transduction efficiency, reduced immunogenicity, and enhanced tissue targeting. Future advances that continue to integrate such multi-disciplinary approaches will further drive the clinical translation of AAV-based therapies. © 2025 The Authors

关键词： AAV directed evolution gene therapy high-throughput screening machine learning next generation sequencing NGS rational design

来源：评论

学校读者我要写书评

暂无评论

Challenges in Developing MOF-Based Membranes for Gas Separation

引用

Langmuir 2023年第8期39卷 2871-2880页

作者： Kang, Dun-Yen Lee, Jong Suk Department of Chemical Engineering National Taiwan University No. 1 Sec. 4 Roosevelt Road Taipei10617 Taiwan International Graduate Program of Molecular Science and Technology National Taiwan University No. 1 Sec. 4 Roosevelt Road Taipei10617 Taiwan Center of Atomic Initiative for New Materials National Taiwan University No. 1 Sec. 4 Roosevelt Road Taipei10617 Taiwan Department of Chemical and Biomolecular Engineering Sogang University Baekbeom-ro 35 Seoul4107 Korea Republic of Institute of Emergent Materials Sogang University 35 Baekbeom-ro Seoul4107 Korea Republic of

Metal-organic frameworks (MOFs) are promising candidates for membrane gas separation. MOF-based membranes include pure MOF membranes and MOF-based mixed matrix membranes (MMMs). This Perspective discusses the challenges for the next stage of the development of MOF-based membranes based on research conducted in the past decade. We focused on three major issues associated with pure MOF membranes. First, some MOF compounds have been overstudied, despite the availability of numerous MOFs. Second, gas adsorption and diffusion in MOFs are often independently investigated. The correlation between adsorption and diffusion has seldom been discussed. Third, we identify the importance of characterizing the gas distribution in MOFs to understand the structure-property relationships for gas adsorption and diffusion in MOF membranes. For MOF-based MMMs, engineering the MOF-polymer interface is essential for achieving the desired separation performance. Various approaches to modify the MOF surface or polymer molecular structure have been proposed to improve the MOF-polymer interface. Herein, we present defect engineering as a facile and efficient approach for engineering the MOF-polymer interfacial morphology and its extended application for various gas separations. © 2023 American Chemical Society.

关键词： Organometallics

来源：评论

学校读者我要写书评

暂无评论

High Pressure Rheology of Gas Hydrate in Multiphase Flow Systems 5th

High Pressure Rheology of Gas Hydrate in Multiphase Flow Sys...

引用

5th International Conference in Ocean engineering, ICOE 2019

作者： Pandey, Gaurav Sangwai, Jitendra S. Department of Petroleum Engineering and Earth Sciences University of Petroleum and Energy Studies Dehradun248007 India Gas Hydrate and Flow Assurance Laboratory Petroleum Engineering Program Department of Ocean Engineering Indian Institute of Technology Madras Chennai600036 India Department of Chemical and Biomolecular Engineering National University of Singapore Singapore117585 Singapore

ISBN: (纸本)9789811585050

The measurement of the rheological properties of gas hydrate slurries necessitates the high pressure rheometer that can provide a proper mixing inside the pressure cell during hydrate formation from two multiphase fluids, water and gas. However, the hydrate formation is highly challenging in conventional cup and bob geometry due to its plane surface. To overcome this, the present work focuses on the study of high pressure rheology for hydrate slurries formed from water-heptane (C7H16) system using a high pressure cell in Anton-Paar® (MCR-52) rheometer and a modified Couette geometry which enables the measurement of rheological studies of multiphase hydrate system. It was observed that the hydrate slurries exhibit shear thinning behavior. The present study provides an important information about the rheology of methane hydrate slurries formed from multiphase systems for flow assurance applications. © 2021, Springer Nature Singapore Pte Ltd.

关键词： Gas hydrates

来源：评论

学校读者我要写书评

暂无评论

Comment on: “Development of a CLDN18.2-targeting immuno-PET probe for non-invasive imaging in gastrointestinal tumors”

引用

Journal of Pharmaceutical Analysis 2023年第9期13卷 958-959页

作者： Cuicui Li Xiaoyuan Chen Jingjing Zhang Department of Diagnostic Radiology Yong Loo Lin School of MedicineNational University of SingaporeSingapore119074Singapore Clinical Imaging Research Centre Centre for Translational MedicineYong Loo Lin School of MedicineNational University of SingaporeSingapore117599Singapore Department of Nuclear Medicine Beijing Friendship Hospital Affiliated to Capital Medical UniversityBeijing100050China Nanomedicine Translational Research Program Yong Loo Lin School of MedicineNational University of SingaporeSingapore117597Singapore Departments of Surgery Chemical and Biomolecular Engineeringand Biomedical EngineeringYong Loo Lin School of Medicine and College of Design and EngineeringNational University of SingaporeSingapore119074Singapore Institute of Molecular and Cell Biology Agency for ScienceTechnologyand Research(A*STAR)61 Biopolis DriveProteosSingapore138673Singapore

In the ever-evolving landscape of cancer research and treatment,the quest for novel and non-invasive imaging techniques has become crucial for accurate diagnosis and effective *** study[1]successfully developed a good manufacturing practices(GMP)grade ^(89)Zr-labeled anti-Claudin18.2(CLDN18.2)recombinant humanized antibody TST001.^(89)Zr-DFO-TST001 exhibited high radiochemical purity(>99%)and specific activity(24.15±1.34 GBq/mmol).It demonstrated good specificity and rapid tumor accumulation in vivo and in *** immuno-PET imaging,it enables non-invasive visualization and quantification of CLDN18.2 expression level in CLDN18.2-positive gastrointestinal tumor models.

关键词： CLDN1 gastrointestinal diagnosis

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：